Ausgewählte Publikationen der Charité
Die Wissenschaftlerinnen und Wissenschaftler der Charité veröffentlichen mehr als 4.000 Fachpublikationen im Jahr.
Hier stellen wir Ihnen pro Monat zehn ausgewählte Publikationen vor.
Sie befinden sich hier:
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Open Data markiert Publikationen mit offen geteilten Daten. Voraussetzungen für Open Data sind die freie Verfügbarkeit der Originaldaten, maschinenlesbares Format und ein eindeutiger Verweis auf Open Data im Volltext nach den Kriterien des BIH Quest Centers.
Publikationen 2021
Juni 2021
Autoren:von Schwartzenberg RJ et al.
Titel:Caloric restriction disrupts the microbiota and colonization resistance.
Zeitschrift (Journal):Nature. 2021 Jun 23. doi: 10.1038/s41586-021-03663-4. :Seiten (Pages):
Aus der Charité: von Schwartzenberg RJ, Dickmann S, Friedrich M, Mai K, Spranger J.
Autoren:Mimitou EP et al.
Titel:Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.
Zeitschrift (Journal):Nat Biotechnol. 2021 Jun 3. doi: 10.1038/s41587-021-00927-2. :Seiten (Pages):
Aus der Charité: Ludwig LS.
Autoren:Ghadjar P et al.
Titel:Dose-intensified Versus Conventional-dose Salvage Radiotherapy for Biochemically Recurrent Prostate Cancer After Prostatectomy: The SAKK 09/10 Randomized Phase 3 Trial.
Zeitschrift (Journal):Eur Urol. 2021 Jun 14:S0302-2838(21)01802-9. :Seiten (Pages):
Aus der Charité: Ghadjar P, Wust P.Autoren:Aschman T et al.
Titel:Association Between SARS-CoV-2 Infection and Immune-Mediated Myopathy in Patients Who Have Died.
Zeitschrift (Journal):JAMA Neurol. 2021 Jun 11. doi: 10.1001/jamaneurol.2021.2004. :Seiten (Pages):
Aus der Charité: Aschman T, Schneider J, Greuel S, Meinhardt J, Streit S, Goebel HH, Büttnerova I, Elezkurtaj S, Scheibe F, Radke J, Meisel C, Drosten C, Radbruch H, Heppner FL, Corman VM, Stenzel W.Autoren:Rincon-Arevalo H et al.
Titel:Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients.
Zeitschrift (Journal):Sci Immunol. 2021 Jun 15;6(60):eabj1031. :Seiten (Pages):
Aus der Charité: Rincon-Arevalo H, Choi M, Stefanski AL, Halleck F, Weber U, Szelinski F, Sattler A, Kotsch K, Chen Y, Burmester GR, Eckardt KU, Budde K, Mashreghi MF, Schrezenmeier E, Dörner T.
Autoren:Peng Y et al.
Titel:Spatially structured inhibition defined by polarized parvalbumin interneuron axons promotes head direction tuning.
Zeitschrift (Journal):Sci Adv. 2021 Jun 16;7(25):eabg4693. :Seiten (Pages):
Aus der Charité: Peng Y, Barreda Tomas FJ, Vida I, Geiger JRP.
Autoren:Gassen NC et al.
Titel:SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Zeitschrift (Journal):Nat Commun. 2021 Jun 21;12(1):3818. :Seiten (Pages):
Aus der Charité: Papies J, Emanuel J, Chua RL, Heinemann N, Weege F, Hönzke K, Aschman T, Schroeder S, Richter A, Niemeyer D, Hoffmann K, Heppner FL, Corman VM, Hocke AC, Morkel M, Conrad C, Eils R, Radbruch H, Drosten C, Müller MA.Autoren:Gabriel CH et al.
Titel:Live-cell imaging of circadian clock protein dynamics in CRISPR-generated knock-in cells.
Zeitschrift (Journal):Nat Commun. 2021 Jun 18;12(1):3796. :Seiten (Pages):
Aus der Charité: Gabriel CH, Del Olmo M, Jäger M, Reischl S, van Dijk H, Ulbricht C, Koller B, Grudziecki A, Maier B, Zemojtel T, Granada AE, Herzel H, Kramer A.Autoren:Friedrich C et al.
Titel:Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories.
Zeitschrift (Journal):Nat Commun. 2021 Jun 11;12(1):3576. :Seiten (Pages):
Aus der Charité: Friedrich C, Schallenberg S, Kirchner M, Ziehm M, Niquet S, Neudecker J, Klauschen F, Mertins P.Autoren:Dahlet T et al.
Titel:E2F6 initiates stable epigenetic silencing of germline genes during embryonic development.
Zeitschrift (Journal):Nat Commun. 2021 Jun 11;12(1):3582. :Seiten (Pages):
Aus der Charité: Truss M, Frede U, Kottnik S, Hansen P, Luz U, Alvarez G, Hecht J, Robinson PN, Hagemeier C.
Mai 2021
Autoren:Jones TC et al.
Titel:Estimating infectiousness throughout SARS-CoV-2 infection course.
Zeitschrift (Journal):Science. 2021 May 25:eabi5273. :Seiten (Pages):
Aus der Charité: Jones TC, Mühlemann B, Veith T, Schneider J, Beheim-Schwarzbach J, Bleicker T, Tesch J, Schmidt ML, Sander LE, Kurth F, Menzel P, Schwarzer R, Zuchowski M, Hofmann J, Stein A, Edelmann A, Corman VM, Drosten C.
Autoren:Correll CU et al.
Titel:Efficacy and acceptability of pharmacological, psychosocial, and brain stimulation interventions in children and adolescents with mental disorders: an umbrella review.
Zeitschrift (Journal):World Psychiatry. 2021 Jun;20(2):244-275. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Haeusler KG et al.
Titel:Systematic monitoring for detection of atrial fibrillation in patients with acute ischaemic stroke (MonDAFIS): a randomised, open-label, multicentre study.
Zeitschrift (Journal):Lancet Neurol. 2021 Jun;20(6):426-436. :Seiten (Pages):
Aus der Charité: Haeusler KG, Kunze C, Tütüncü S, Olma MC, Endres M.Autoren:Filippatos G et al.
Titel:Finerenone Reduces Onset of Atrial Fibrillation in Patients with Chronic Kidney Disease and Type 2 Diabetes.
Zeitschrift (Journal):J Am Coll Cardiol. 2021 May 4:S0735-1097(21)04966-4. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Højlund M et al.
Titel:Standard versus reduced dose of antipsychotics for relapse prevention in multi-episode schizophrenia: a systematic review and meta-analysis of randomised controlled trials.
Zeitschrift (Journal):Lancet Psychiatry. 2021 Jun;8(6):471-486. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Diekhoff T et al.
Titel:Choose wisely: imaging for diagnosis of axial spondyloarthritis.
Zeitschrift (Journal):Ann Rheum Dis. 2021 May 28:annrheumdis-2021-220136. :Seiten (Pages):
Aus der Charité: Diekhoff T, Radny F, Ziegeler K, Proft F, Greese J, Deppe D, Biesen R, Hermann KG, Poddubnyy D.Autoren:Kennedy KM et al.
Titel:Fetal meconium does not have a detectable microbiota before birth.
Zeitschrift (Journal):Nat Microbiol. 2021 May 10. doi: 10.1038/s41564-021-00904-0. :Seiten (Pages):
Aus der Charité: Gerlach MJ, Adam T, Heimesaat MM, Braun T.Autoren:Brandt AU et al.
Titel:Association of a Marker of N-Acetylglucosamine With Progressive Multiple Sclerosis and Neurodegeneration.
Zeitschrift (Journal):JAMA Neurol. 2021 May 10:e211116. :Seiten (Pages):
Aus der Charité: Brandt AU, Bellmann-Strobl J, Zimmermann HG, Chien C, Dörr J, Wuerfel JT, Paul F.Autoren:Patzke C et al.
Titel:Cannabinoid receptor activation acutely increases synaptic vesicle numbers by activating synapsins in human synapses.
Zeitschrift (Journal):Mol Psychiatry. 2021 Apr 30. doi: 10.1038/s41380-021-01095-0. :Seiten (Pages):
Aus der Charité: Brockmann MM, Fenske P, Rosenmund C.Autoren:Hobohm L et al.
Titel:Role of angiopoietin-2 in venous thrombus resolution and chronic thromboembolic disease.
Zeitschrift (Journal):Eur Respir J. 2021 May 13:2004196. :Seiten (Pages):
Aus der Charité: Lankeit M.
April 2021
Autoren:Eckardt KU et al.
Titel:Safety and Efficacy of Vadadustat for Anemia in Patients Undergoing Dialysis.
Zeitschrift (Journal):N Engl J Med. 2021 Apr 29;384(17):1601-1612. :Seiten (Pages):
Aus der Charité: Eckardt KU.Autoren:Chertow GM et al.
Titel:Vadadustat in Patients with Anemia and Non-Dialysis-Dependent CKD.
Zeitschrift (Journal):N Engl J Med. 2021 Apr 29;384(17):1589-1600. :Seiten (Pages):
Aus der Charité: Eckardt KU.Autoren:Andrade J et al.
Titel:Control of endothelial quiescence by FOXO-regulated metabolites.
Zeitschrift (Journal):Nat Cell Biol. 2021 Apr;23(4):413-423. :Seiten (Pages):
Aus der Charité: Potente M.Autoren:Kishimoto T, Hagi K, Kurokawa S, Kane JM, Correll CU.
Titel:Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised, cohort, and pre-post studies.
Zeitschrift (Journal):Lancet Psychiatry. 2021 May;8(5):387-404. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Siegert E et al.
Titel:Systemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology.
Zeitschrift (Journal):Acta Neuropathol. 2021 Apr 17. doi: 10.1007/s00401-021-02305-3. :Seiten (Pages):
Aus der Charité: Siegert E, Uruha A, Goebel HH, Preuße C, Casteleyn V, Kleefeld F, Burmester GR, Schneider U, Höppner J, Hahn K, Dittmayer C, Stenzel W.Autoren:Ferreira-Gomes M et al.
Titel:SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself.
Zeitschrift (Journal):Nat Commun. 2021 Mar 30;12(1):1961. :Seiten (Pages):
Aus der Charité: Tizian C, Pascual-Reguant A, Mothes R, Frischbutter S, Matz M, Ostendorf L, Maurer M, Schönrich G, Raftery M, Kallinich T, Mall MA, Angermair S, Treskatsch S, Dörner T, Corman VM, Diefenbach A, Volk HD, Elezkurtaj S, Hauser AE, Radbruch H, Witkowski M, Mashreghi MF.Autoren:Maifeld A et al.
Titel:Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients.
Zeitschrift (Journal):Nat Commun. 2021 Mar 30;12(1):1970. :Seiten (Pages):
Aus der Charité: Maifeld A, Bartolomaeus H, Löber U, Avery EG, Steckhan N, Markó L, Wilck N, Šušnjar U, Mähler A, Chen CY, Dechend R, Michalsen A, Müller DN, Forslund SK.
Autoren:Qi S et al.
Titel:Reward Processing in Novelty Seekers: A Transdiagnostic Psychiatric Imaging Biomarker.
Zeitschrift (Journal):Biol Psychiatry. 2021 Jan 30:S0006-3223(21)00078-0. :Seiten (Pages):
Aus der Charité: Schumann G, Chu C, Quinlan EB, Desrivières S, Heinz A, Walter H.Autoren:Fritz F et al.
Titel:VirtualTaste: a web server for the prediction of organoleptic properties of chemical compounds.
Zeitschrift (Journal):Nucleic Acids Res. 2021 Apr 27:gkab292. :Seiten (Pages):
Aus der Charité: Fritz F, Preissner R, Banerjee P.Autoren:Steinhaus R et al.
Titel:MutationTaster2021.
Zeitschrift (Journal):Nucleic Acids Res. 2021 Apr 24:gkab266. :Seiten (Pages):
Aus der Charité: Steinhaus R, Proft S, Schuelke M, Schwarz JM, Seelow D.
März 2021
Autoren:Locatelli F et al.
Titel:Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial.
Zeitschrift (Journal):JAMA. 2021 Mar 2;325(9):843-854. :Seiten (Pages):
Aus der Charité: Eckert C, von Stackelberg A.Autoren:Messner CB et al.
Titel:Ultra-fast proteomics with Scanning SWATH.
Zeitschrift (Journal):Nat Biotechnol. 2021 Mar 25. doi: 10.1038/s41587-021-00860-4. :Seiten (Pages):
Aus der Charité: Messner CB, Demichev V, Freiwald A, Jürgens L, Suttorp N, Sander LE, Kurth F, Mülleder M, Ralser M.Autoren:Guigay J et al.
Titel:Cetuximab, docetaxel, and cisplatin versus platinum, fluorouracil, and cetuximab as first-line treatment in patients with recurrent or metastatic head and neck squamous-cell carcinoma (GORTEC 2014-01 TPExtreme): a multicentre, open-label, randomised, phase 2 trial.
Zeitschrift (Journal):Lancet Oncol. 2021 Apr;22(4):463-475. :Seiten (Pages):
Aus der Charité: Keilholz U.Autoren:Hagi K et al.
Titel:Association Between Cardiovascular Risk Factors and Cognitive Impairment in People With Schizophrenia: A Systematic Review and Meta-analysis.
Zeitschrift (Journal):JAMA Psychiatry. 2021 Mar 3:e210015. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Thomas C et al.
Titel:TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma.
Zeitschrift (Journal):Acta Neuropathol. 2021 Mar 23. doi: 10.1007/s00401-021-02300-8. :Seiten (Pages):
Aus der Charité: Träger M, Förster A, Geiler C, Onken J, Vajkoczy P, Heppner FL, Capper D, Koch A, Kaul D, Schweizer L.Autoren:Inak G et al.
Titel:Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Zeitschrift (Journal):Nat Commun. 2021 Mar 26;12(1):1929. :Seiten (Pages):
Aus der Charité: Secker C, Zink A, Henke MT, Priller J, Stenzel W, Schuelke M.Autoren:Pascual-Reguant A et al.
Titel:Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells.
Zeitschrift (Journal):Nat Commun. 2021 Mar 19;12(1):1737. :Seiten (Pages):
Aus der Charité: Pascual-Reguant A, Mothes R, Uecker R, Kotsch K, Romagnani C, Hauser AE.Autoren:Schiweck J et al.
Titel:Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking.
Zeitschrift (Journal):Nat Commun. 2021 Mar 5;12(1):1490. :Seiten (Pages):
Aus der Charité: Schiweck J, Murk K, Ledderose J, Münster-Wandowski A, Ornaghi M, Vida I, Eickholt BJ.Autoren:Brisson NM et al.
Titel:Association of machine learning based predictions of medial knee contact force with cartilage loss over 2.5 years in knee osteoarthritis.
Zeitschrift (Journal):Arthritis Rheumatol. 2021 Mar 24. doi: 10.1002/art.41735. :Seiten (Pages):
Aus der Charité: Brisson NM, Damm P, Duda GN.Autoren:Rasche A et al.
Titel:A hepatitis B virus causes chronic infections in equids worldwide.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2013982118. :Seiten (Pages):
Aus der Charité: Rasche A, Goldmann N, Moreira-Soto A, de Oliveira Carneiro I, Drexler JF.Autoren:Waterstraat G et al.
Titel:Noninvasive neuromagnetic single-trial analysis of human neocortical population spikes.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2017401118. :Seiten (Pages):
Aus der Charité: Waterstraat G, Curio G.
Febuar 2021
Autoren:Ebinger M et al.
Titel:Association Between Dispatch of Mobile Stroke Units and Functional Outcomes Among Patients With Acute Ischemic Stroke in Berlin.
Zeitschrift (Journal):JAMA. 2021 Feb 2;325(5):454-466. :Seiten (Pages):
Aus der Charité:Ebinger M, Siegerink B, Kunz A, Weber JE, Geisler F, Freitag E, Lange J, Behrens J, Erdur H, Ganeshan R, Liman T, Scheitz JF, Schlemm L, Harmel P, Lorenz-Meyer I, Napierkowski I, Waldschmidt C, Nolte CH, Grittner U, Wiener E, Bohner G, Rohmann JL, Endres M, Audebert HJ.Autoren:Allou L et al.
Titel:Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator.
Zeitschrift (Journal):Nature. 2021 Feb 10. doi: 10.1038/s41586-021-03208-9. :Seiten (Pages):
Aus der Charité: Allou L, Magg A, Schöpflin R, Chan WL, Spielmann M, Cova G, Mundlos S.Autoren:Schmalbrock LK et al.
Titel:Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Zeitschrift (Journal):Blood. 2021 Feb 17:blood.2020007626. :Seiten (Pages):
Aus der Charité: Dolnik A, Sträng E, Bullinger L.Autoren:Nikolay R et al.
Titel:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Zeitschrift (Journal):Mol Cell. 2021 Feb 23:S1097-2765(21)00092-7. :Seiten (Pages):
Aus der Charité: Nikolay R, Hilal T, Qin B, Schwefel D, Bürger J, Loerke J, Flügel T, Selbach M, Spahn CMT.Autoren:Salomon JJ et al.
Titel:Chronic Rhinosinusitis with Nasal Polyps is Associated with Impaired TMEM16A-mediated Epithelial Chloride Secretion.
Zeitschrift (Journal):J Allergy Clin Immunol. 2021 Feb 17:S0091-6749(21)00224-4. :Seiten (Pages):
Aus der Charité: Graeber SY, Mall MA.Autoren:Agostini F et al.
Titel:Multiomics Analysis Provides Insight into the Laboratory Evolution of Escherichia coli toward the Metabolic Usage of Fluorinated Indoles.
Zeitschrift (Journal):ACS Cent Sci. 2021 Jan 27;7(1):81-92. :Seiten (Pages):
Aus der Charité: Agostini F.Autoren:Mencacci NE et al.
Titel:Bi-allelic variants in TSPOAP1, encoding the active zone protein RIMBP1, cause autosomal recessive dystonia.
Zeitschrift (Journal):J Clin Invest. 2021 Feb 4:140625. :Seiten (Pages):
Aus der Charité: Brockmann MM, Rosenmund C.Autoren:Dong P et al.
Titel:A Dual Fluorescence-Spin Label Probe for Visualization and Quantification of Target Molecules in Tissue by Multiplexed FLIM - EPR Spectroscopy.
Zeitschrift (Journal):Angew Chem Int Ed Engl. 2021 Feb 5. doi: 10.1002/anie.202012852. :Seiten (Pages):
Aus der Charité: Dong P, Lohan SB, Patzelt A, Meinke MC.Autoren:Iftekhar A et al.
Titel:Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
Zeitschrift (Journal):Nat Commun. 2021 Feb 12;12(1):1003. :Seiten (Pages):
Aus der Charité: Berger H, Heuberger J, Sigal M.Autoren:Niehus S et al.
Titel:PopDel identifies medium-size deletions simultaneously in tens of thousands of genomes.
Zeitschrift (Journal):Nat Commun. 2021 Feb 1;12(1):730. :Seiten (Pages):
Aus der Charité: Niehus S, Sulem P, Kehr B.
Januar 2021
Autoren:Lotta LA et al.
Titel:A cross-platform approach identifies genetic regulators of human metabolism and health.
Zeitschrift (Journal):Nat Genet. 2021 Jan;53(1):54-64. :Seiten (Pages):
Aus der Charité: Langenberg C.Autoren:Vollmer T et al.
Titel:The intratumoral CXCR3 chemokine system is predictive of chemotherapy response in human bladder cancer.
Zeitschrift (Journal):Sci Transl Med. 2021 Jan 13;13(576):eabb3735. :Seiten (Pages):
Aus der Charité: Vollmer T, Schlickeiser S, Amini L, Schulenberg S, Wendering DJ, Jurisch A, Noster R, Kunkel D, Brindle NR, Savidis I, Akyüz L, Roch T, Babel N, Reinke P, Volk HD, Schmueck-Henneresse M.Autoren:Westhovens R et al.
Titel:Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial.
Zeitschrift (Journal):Ann Rheum Dis. 2021 Jan 15:annrheumdis-2020-219213. :Seiten (Pages):
Aus der Charité: Burmester GR .Autoren:Deshpande D et al.
Titel:Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy.
Zeitschrift (Journal):Nat Commun. 2021 Jan 18;12(1):426. :Seiten (Pages):
Aus der Charité: Deshpande D, Klose CSN.Autoren:Rodríguez de Los Santos M et al.
Titel:A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):e2014481118. :Seiten (Pages):
Aus der Charité: Rodríguez de Los Santos M, Rivalan M, Stumpf A, Velasquez LM, Voigt A, Long M, Vogt G, Fischer-Zirnsak B, Horn D, Mundlos S, Kornak U, Schmitz D, Winter Y.Autoren:Horn D et al.
Titel:Biallelic truncating variants in MAPKAPK5 cause a new developmental disorder involving neurological, cardiac, and facial anomalies combined with synpolydactyly.
Zeitschrift (Journal):Genet Med. 2021 Jan 13. doi: 10.1038/s41436-020-01052-2. :Seiten (Pages):
Aus der Charité: Horn D, Schwartzmann S, Ehmke N, Boschann F.Autoren:Cheret C et al.
Titel:Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Zeitschrift (Journal):Cell Rep. 2021 Jan 12;34(2):108623. :Seiten (Pages):
Aus der Charité: Cheret C, Ahnert-Hilger G.Autoren:Lipp T et al.
Titel:Heterogeneity of Pollen Food Allergy Syndrome in Seven Southern European Countries: the @IT.2020 Multicenter Study.
Zeitschrift (Journal):Allergy. 2021 Jan 25. doi: 10.1111/all.14742. :Seiten (Pages):
Aus der Charité: Lipp T, Hoffmann TM, Potapova E, Matricardi PM, Dramburg S.Autoren:Simsek C et al.
Titel:At Least Seven Distinct Rotavirus Genotype Constellations in Bats with Evidence of Reassortment and Zoonotic Transmissions.
Zeitschrift (Journal):mBio. 2021 Jan 19;12(1):e02755-20. :Seiten (Pages):
Aus der Charité: Corman VM, Rasche A, Drosten C, Drexler JF, Matthijnssens J.Autoren:Wolk K et al.
Titel:Activity and components of the G-CSF pathway in hidradenitis suppurativa.
Zeitschrift (Journal):Br J Dermatol. 2021 Jan 5. doi: 10.1111/bjd.19795. :Seiten (Pages):
Aus der Charité: Wolk K, Brembach TC, Cucinotta S, Pokrywka A, Irmer ML, Triebus J, Witte-Händel E, Volk HD, Ghoreschi K, Sabat R.
Publikationen 2020
Dezember 2020
Autoren:Veenvliet JV et al.
Titel:Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites.
Zeitschrift (Journal):Science. 2020 Dec 11;370(6522):eaba4937. :Seiten (Pages):
Aus der Charité: Herrmann BG.Autoren:Trump S et al.
Titel:Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19.
Zeitschrift (Journal):Nat Biotechnol. 2020 Dec 24. doi: 10.1038/s41587-020-00796-1. :Seiten (Pages):
Aus der Charité: Trump S, Lukassen S, Anker MS, Chua RL, Liebig J, Thürmann L, Corman VM, Loske J, Krieger T, Hennig BP, Messingschlager M, Pott F, Kazmierski J, Twardziok S, Albrecht JP, Eils J, Hadzibegovic S, Lena A, Heidecker B, Bürgel T, Steinfeldt J, Goffinet C, Kurth F, Witzenrath M, Ishaque N, Sander LE, Drosten C, Eils R, Conrad C, Landmesser U, Lehmann I.Autoren:Abraham WT et al.
Titel:Effect of empagliflozin on exercise ability and symptoms in heart failure patients with reduced and preserved ejection fraction, with and without type 2 diabetes.
Zeitschrift (Journal):Eur Heart J. 2020 Dec 22:ehaa943. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Meinhardt J et al.
Titel:Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.
Zeitschrift (Journal):Nat Neurosci. 2020 Nov 30. doi: 10.1038/s41593-020-00758-5. :Seiten (Pages):
Aus der Charité: Meinhardt J, Radke J, Dittmayer C, Mothes R, Schneider J, Brünink S, Greuel S, Lehmann M, Hassan O, Aschman T, Schumann E, Chua RL, Conrad C, Eils R, Stenzel W, Windgassen M, Rößler L, Goebel HH, Martin H, Scheibe F, Körtvélyessy P, Siegmund B, Kühl AA, Elezkurtaj S, Horst D, Oesterhelweg L, Tsokos M, Drosten C, Corman VM, Radbruch H, Heppner FL.Autoren:Kraushar ML et al.
Titel:Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.
Zeitschrift (Journal):Mol Cell. 2020 Dec 17:S1097-2765(20)30837-6. :Seiten (Pages):
Aus der Charité: Kraushar ML, Krupp F, Turko P, Ambrozkiewicz MC, Sprink T, Schaub T, Münster-Wandowski A, Bürger J, Yamamoto H, Tarabykin V, Vida I, Spahn CMT.Autoren:Piepoli MF et al.
Titel:OUTSTEP-HF: randomised controlled trial comparing short-term effects of sacubitril/valsartan versus enalapril on daily physical activity in patients with chronic heart failure with reduced ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Dec 13. doi: 10.1002/ejhf.2076. :Seiten (Pages):
Aus der Charité: Edelmann F.Autoren:Anker SD et al.
Titel:Baseline Characteristics of Patients with Heart Failure with Preserved Ejection Fraction in the EMPEROR-Preserved Trial.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Nov 29. doi: 10.1002/ejhf.2064. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Grinat J et al.
Titel:The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Zeitschrift (Journal):Nat Commun. 2020 Dec 21;11(1):6422. :Seiten (Pages):
Aus der Charité: Heuberger J.Autoren:Pietzner M et al.
Titel:Genetic architecture of host proteins involved in SARS-CoV-2 infection.
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Titel:SLAMF7 and IL-6R define distinct cytotoxic versus helper memory CD8+ T cells.
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November 2020
Autoren:Clément K et al.
Titel:Setmelanotide POMC and LEPR Phase 3 Trial Investigators. Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.
Zeitschrift (Journal):Lancet Diabetes Endocrinol. 2020 Dec;8(12):960-970. :Seiten (Pages):
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Titel:EMPEROR-Reduced Trial Committees and Investigators. Effect of Empagliflozin on Cardiovascular and Renal Outcomes in Patients With Heart Failure by Baseline Diabetes Status - Results from the EMPEROR-Reduced Trial.
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Titel:Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues.
Zeitschrift (Journal):Immunity. 2020 Nov 17;53(5):1015-1032.e8. :Seiten (Pages):
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Titel:Single nucleus and in situ RNA sequencing reveals cell topographies in the human pancreas.
Zeitschrift (Journal):Gastroenterology. 2020 Nov 16:S0016-5085(20)35399-3. :Seiten (Pages):
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Titel:Platelet Extracellular Vesicles mediate Transfusion-related Acute Lung Injury by imbalancing the Sphingolipid Rheostat.
Zeitschrift (Journal):Blood. 2020 Nov 24:blood.2020005985. :Seiten (Pages):
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Titel:Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
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Titel:Influence of COVID-19 pandemic on decisions for the management of people with inflammatory rheumatic and musculoskeletal diseases: a survey among EULAR countries.
Zeitschrift (Journal):Ann Rheum Dis. 2020 Nov 6:annrheumdis-2020-218697. :Seiten (Pages):
Aus der Charité: Buttgereit F.Autoren:Holstein J et al.
Titel:Immunophenotyping in pemphigus reveals a Th17/Tfh17-dominated immune response promoting desmoglein1/3-specific autoantibody production.
Zeitschrift (Journal):J Allergy Clin Immunol. 2020 Nov 19:S0091-6749(20)31624-9. :Seiten (Pages):
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Titel:Ventricular tachycardia, premature ventricular contractions, and mortality in unselected patients with lung, colon, or pancreatic cancer: a prospective study.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Nov 22. doi: 10.1002/ejhf.2059. :Seiten (Pages):
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Titel:A novel giant non-cholinergic striatal interneuron restricted to the ventrolateral striatum coexpresses Kv3.3 potassium channel, parvalbumin, and the vesicular GABA transporter.
Zeitschrift (Journal):Mol Psychiatry. 2020 Nov 14. doi: 10.1038/s41380-020-00948-4. :Seiten (Pages):
Aus der Charité: Lebenheim L, Booker SA, Derst C, Weiss T, Wagner F, Gruber C, Vida I, Veh RW.
Oktober 2020
Autoren:M Real F et al.
Titel:The mole genome reveals regulatory rearrangements associated with adaptive intersexuality.
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Titel:A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
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Titel:Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial.
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Titel:Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study.
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Titel:Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic KLF4 mutations predominantly in low-grade regions.
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Titel:Metal-Specific Biomaterial Accumulation in Human Peri-Implant Bone and Bone Marrow.
Zeitschrift (Journal):Adv Sci (Weinh). 2020 Aug 3;7(20):2000412. :Seiten (Pages):
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Titel:Safety profile of upadacitinib in rheumatoid arthritis: integrated analysis from the SELECT phase III clinical programme.
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Titel:Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: a randomized, double-blind, placebo-controlled phase 3 trial.
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Titel:Telemonitoring in patients with chronic heart failure and moderate depressed symptoms: results of the Telemedical Interventional Monitoring in Heart Failure (TIM-HF) study.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Oct 15. doi: 10.1002/ejhf.2025. :Seiten (Pages):
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Titel:Phase I study of everolimus, letrozole, and trastuzumab in patients with hormone receptor-positive metastatic breast cancer or other solid tumors.
Zeitschrift (Journal):Clin Cancer Res. 2020 Oct 28:clincanres.2878.2020. :Seiten (Pages):
Aus der Charité: Ballhausen A.
September 2020
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Titel:Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus.
Zeitschrift (Journal):N Engl J Med. 2020 Sep 17;383(12):1149-1155. :Seiten (Pages):
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Titel:Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity.
Zeitschrift (Journal):Acta Neuropathol. 2020 Sep 14. doi: 10.1007/s00401-020-02218-7. :Seiten (Pages):
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Titel:Maternal Psychological Resilience During Pregnancy and Newborn Telomere Length: A Prospective Study.
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Titel:Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis.
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Titel:CRISPR-Cas9-Edited Tacrolimus-Resistant Antiviral T Cells for Advanced Adoptive Immunotherapy in Transplant Recipients.
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Titel:SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells.
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Titel:Selenium deficiency is linearly associated with hypoglycemia in healthy adults.
Zeitschrift (Journal):Redox Biol. 2020 Sep 1;37:101709. :Seiten (Pages):
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Titel:Treatment and Mortality of Hemophagocytic Lymphohistiocytosis in Adult Critically Ill Patients: A Systematic Review With Pooled Analysis.
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Titel:Implications for post critical illness trial design: sub-phenotyping trajectories of functional recovery among sepsis survivors.
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Titel:Vitamin A controls the allergic response through T follicular helper cell as well as plasmablast differentiation.
Zeitschrift (Journal):Allergy. 2020 Sep 7. doi: 10.1111/all.14581. :Seiten (Pages):
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August 2020
Autoren:Sadik A et al.
Titel:IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Zeitschrift (Journal):Cell. 2020 Sep 3;182(5):1252-1270.e34. :Seiten (Pages):
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Titel:Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
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Titel:Randomized Comparison of Pazopanib and Doxorubicin as First-Line Treatment in Patients With Metastatic Soft Tissue Sarcoma Age 60 Years or Older: Results of a German Intergroup Study.
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Titel:Transcatheter tricuspid valve repair in the setting of heart failure with preserved or reduced left ventricular ejection fraction.
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Titel:Effects of Olanzapine Combined With Samidorphan on Weight Gain in Schizophrenia: A 24-Week Phase 3 Study.
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Titel:SARS-CoV-2 specific T-cell responses and correlations with COVID-19 patient predisposition.
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Titel:Estrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation.
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Titel:Muscle wasting as an independent predictor of survival in patients with chronic heart failure.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2020 Aug 6. doi: 10.1002/jcsm.12603. :Seiten (Pages):
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Titel:The human liver matrisome - Proteomic analysis of native and fibrotic human liver extracellular matrices for organ engineering approaches.
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Titel:The ILLS Laparoscopic Liver Surgery Fellow Skills Curriculum.
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Juli 2020
Autoren:Burmester GR et al.
Titel:Continuing versus tapering glucocorticoids after achievement of low disease activity or remission in rheumatoid arthritis (SEMIRA): a double-blind, multicentre, randomised controlled trial.
Zeitschrift (Journal):Lancet. 2020 Jul 25;396(10246):267-276. :Seiten (Pages):
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Titel:SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19.
Zeitschrift (Journal):Nature. 2020 Jul 29. doi: 10.1038/s41586-020-2598-9. :Seiten (Pages):
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Titel:Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age.
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Titel:Intestinal Virome Signature Associated With Severity of Nonalcoholic Fatty Liver Disease.
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Titel:TWIST1 Drives Smooth Muscle Cell Proliferation in Pulmonary Hypertension via Loss of GATA-6 and BMPR2.
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Titel:Comparison of Organoid Swelling and in vivo Biomarkers of CFTR Function to Determine Effects of Lumacaftor-ivacaftor in Patients with Cystic Fibrosis Homozygous for the F508del Mutation.
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Titel:Dynamic conjugate F-SHARP microscopy.
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Titel:Hypoxic-Ischemic Encephalopathy Evaluated by Brain Autopsy and Neuroprognostication After Cardiac Arrest.
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Titel:H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients.
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Titel:A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder.
Zeitschrift (Journal):Nat Commun. 2020 Jul 3;11(1):3364. :Seiten (Pages):
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Juni 2020
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Titel:Association of Migraine With Aura and Other Risk Factors With Incident Cardiovascular Disease in Women.
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Titel:COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis.
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Titel:Phosphodiesterase 3A and Arterial Hypertension.
Zeitschrift (Journal):Circulation. 2020 Jul 14;142(2):133-149. :Seiten (Pages):
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Titel:Bacterial citrullinated epitopes generated by Porphyromonas gingivalis infection-a missing link for ACPA production.
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Titel:Phenotype and risk factors of venom-induced anaphylaxis: a case-control study of the European Anaphylaxis Registry.
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Titel:Drug allergy to CFTR modulator therapy associated with lumacaftor-specific CD4+ T lymphocytes.
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Titel:Clozapine modulates retinoid homeostasis in human brain and normalizes serum retinoic acid deficit in patients with schizophrenia.
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Titel:Epilepsy-causing STX1B mutations translate altered protein functions into distinct phenotypes in mouse neurons.
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Titel:GFR in Healthy Aging: an Individual Participant Data Meta-Analysis of Iohexol Clearance in European Population-Based Cohorts.
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Titel:Neutrophil Gelatinase-Associated Lipocalin Protects from ANCA-Induced GN by Inhibiting TH17 Immunity.
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Mai 2020
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Titel:Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
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Titel:Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells.
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Titel:Safety of 80 antidepressants, antipsychotics, anti-attention-deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta-review of 78 adverse effects.
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Titel:Use of all cause mortality to quantify the consequences of covid-19 in Nembro, Lombardy: descriptive study.
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Titel:Investigation of a COVID-19 outbreak in Germany resulting from a single travel-associated primary case: a case series.
Zeitschrift (Journal):Lancet Infect Dis. 2020 May 15:S1473-3099(20)30314-5. :Seiten (Pages):
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Titel:Obesity and weight loss are inversely related to mortality and cardiovascular outcome in prediabetes and type 2 diabetes: data from the ORIGIN trial.
Zeitschrift (Journal):Eur Heart J. 2020 May 13:ehaa293. :Seiten (Pages):
Aus der Charité: Doehner W, Anker SD.Autoren:Lefere S et al.
Titel:Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages.
Zeitschrift (Journal):J Hepatol. 2020 Apr 29:S0168-8278(20)30269-5. :Seiten (Pages):
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Titel:Canakinumab for Treatment of Adult-Onset Still's Disease to Achieve Reduction of Arthritic Manifestation (CONSIDER): phase II, randomised, double-blind, placebo-controlled, multicentre, investigator-initiated trial.
Zeitschrift (Journal):Ann Rheum Dis. 2020 May 13:annrheumdis-2020-217155. :Seiten (Pages):
Aus der Charité: Kedor C, Zernicke J, Feist E.Autoren:Rastogi S et al.
Titel:PGE₂ deficiency predisposes to anaphylaxis by causing mast cell hyper-responsiveness.
Zeitschrift (Journal):J Allergy Clin Immunol. 2020 May 11:S0091-6749(20)30639-4. :Seiten (Pages):
Aus der Charité: Rastogi S, Willmes DM, Nassiri M, Babina M, Worm M.Autoren:Edelmann F et al.
Titel:Rationale and Study Design of OUTSTEP-HF: A Randomized Controlled Study to Assess the Effect of Sacubitril/Valsartan and Enalapril on Physical Activity measured by Accelerometry in Patients with Heart Failure with Reduced Ejection Fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2020 May 28. doi: 10.1002/ejhf.1919. :Seiten (Pages):
Aus der Charité: Edelmann F.
April 2020
Autoren:Wölfel R et al.
Titel:Virological assessment of hospitalized patients with COVID-2019.
Zeitschrift (Journal):Nature. 2020 Apr 1. doi: 10.1038/s41586-020-2196-x. :Seiten (Pages):
Aus der Charité: Corman VM, Müller MA, Niemeyer D, Jones TC, Bleicker T, Brünink S, Schneider J, Drosten C.Autoren:Kaminski MM et al.
Titel:A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection.
Zeitschrift (Journal):Nat Biomed Eng. 2020 Apr 13. doi: 10.1038/s41551-020-0546-5. :Seiten (Pages):
Aus der Charité: Kaminski MM, Greensmith R.
Autoren:Berndt N et al.
Titel:Functional consequences of metabolic zonation in murine livers: New insights for an old story.
Zeitschrift (Journal):Hepatology. 2020 Apr 14. doi: 10.1002/hep.31274. :Seiten (Pages):
Aus der Charité: Berndt N, Eckstein J, Holzhütter HG.Autoren:Butler J et al.
Titel:Minimal clinically important difference in quality of life scores for patients with heart failure and reduced ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Apr 2. doi: 10.1002/ejhf.1810. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Haase N et al.
Titel:RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Zeitschrift (Journal):J Clin Invest. 2020 Apr 27:99417. :Seiten (Pages):
Aus der Charité: Haase N, Golic M, Herse F, Kräker K, Müller DN, Dechend R.Autoren:Ambrozkiewicz MC et al.
Titel:The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc.
Zeitschrift (Journal):Mol Psychiatry. 2020 Apr 6. doi: 10.1038/s41380-020-0714-8. :Seiten (Pages):
Aus der Charité:Ambrozkiewicz MC, Schaub T, Smorodchenko A, Weber AI, Mueller S, Horan ST, Rosário M, Boehm-Sturm P, Tarabykin V.Autoren:Duerr J et al.
Titel:Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.
Zeitschrift (Journal):Nat Commun. 2020 Apr 24;11(1):2012. :Seiten (Pages):
Aus der Charité: Duerr J, Leitz DHW, Ochs M, Mall MA.Autoren:Nitzan N et al.
Titel:Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway.
Zeitschrift (Journal):Nat Commun. 2020 Apr 23;11(1):1947. :Seiten (Pages):
Aus der Charité: Nitzan N, Beed P, Oldani S, Tukker JJ, Schmitz D.Autoren:Basu Roy R et al.
Titel:Performance of immune-based and microbiological tests in children with TB meningitis in Europe - a multi-center Paediatric Tuberculosis Network European Trials Group (ptbnet) study.
Zeitschrift (Journal):Eur Respir J. 2020 Apr 16:1902004. :Seiten (Pages):
Aus der Charité: Thee S, Krüger R.Autoren:Lukassen S et al.
Titel:SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells.
Zeitschrift (Journal):EMBO J. 2020 Apr 4:e105114. :Seiten (Pages):
Aus der Charité: Lukassen S, Chua RL, Trefzer T, Hennig BP, Conrad C, Eils R.
März 2020
Autoren:Bockstahler M et al.
Titel:Heart-Specific Immune Responses in an Animal Model of AutoimmuneRelated Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation.
Zeitschrift (Journal):Circulation. 2020 Mar 12. doi: 10.1161/CIRCULATIONAHA.119.043171. :Seiten (Pages):
Aus der Charité: Goetzke CC, Neumaier HL, Kespohl M, Landmesser U, Kratzer A, Beling A.Autoren:Flamar AL et al.
Titel:Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity.
Zeitschrift (Journal):Immunity. 2020 Apr 14;52(4):606-619.e6. :Seiten (Pages):
Aus der Charité: Klose CSN, Stokic-Trtica V.Autoren:Hoffmann S et al.
Titel:Complement deposition at the neuromuscular junction in seronegative myasthenia gravis.
Zeitschrift (Journal):Acta Neuropathol. 2020 Mar 10. doi: 10.1007/s00401-020-02147-5. :Seiten (Pages):
Aus der Charité: Hoffmann S, Harms L, Schuelke M, Rückert JC, Goebel HH, Stenzel W, Meisel A.Autoren:Grent-'t-Jong T et al.
Titel:Association of Magnetoencephalographically Measured High-Frequency Oscillations in Visual Cortex With Circuit Dysfunctions in Local and Large-scale Networks During Emerging Psychosis.
Zeitschrift (Journal):JAMA Psychiatry. 2020 Mar 25:e200284. :Seiten (Pages):
Aus der Charité: Grent-'t-Jong T, Uhlhaas PJ.Autoren:Ullah I et al.
Titel:Adult Tissue Extracellular Matrix Determines Tissue Specification of Human iPSC-Derived Embryonic Stage Mesodermal Precursor Cells.
Zeitschrift (Journal):Adv Sci (Weinh). 2020 Jan 21;7(5):1901198. :Seiten (Pages):
Aus der Charité: Ullah I, Busch JF, Rabien A, Ergün B, Stamm C, Hippenstiel S, Reinke P, Kurtz A.Autoren:Kramer F et al.
Titel:Evaluation of high-sensitivity C-reactive protein and uric acid in vericiguat-treated patients with heart failure with reduced ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Mar 25. doi: 10.1002/ejhf.1787. :Seiten (Pages):
Aus der Charité: Pieske B.Autoren:Anker MS et al.
Titel:Increased resting heart rate and prognosis in treatment-naïve unselected cancer patients: results from a prospective observational study.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Mar 23. doi: 10.1002/ejhf.1782. :Seiten (Pages):
Aus der Charité: Anker MS.Autoren:Kespohl M et al.
Titel:Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming.
Zeitschrift (Journal):Sci Adv. 2020 Mar 11;6(11):eaay1109. :Seiten (Pages):
Aus der Charité: Kespohl M, Bredow C, Voß M, Paeschke A, Zickler M, Poller W, Eckstein J, Spranger J, Fähling M, Wirth EK, Berndt N, Beling A.Autoren:Hagner M et al.
Titel:New method for rapid and dynamic quantification of elastase activity on sputum neutrophils from patients with cystic fibrosis using flow cytometry.
Zeitschrift (Journal):Eur Respir J. 2020 Mar 5:1902355. :Seiten (Pages):
Aus der Charité: Mall MA.Autoren:Banerjee P et al.
Titel:SuperCYPsPred-a web server for the prediction of cytochrome activity.
Zeitschrift (Journal):Nucleic Acids Res. 2020 Mar 17:gkaa166. :Seiten (Pages):
Aus der Charité: Banerjee P, Dunkel M, Kemmler E, Preissner R.
Februar 2020
Autoren:Maechler F et al.
Titel:Contact isolation versus standard precautions to decrease acquisition of extended-spectrum β-lactamase-producing Enterobacterales in non-critical care wards: a cluster-randomised crossover trial.
Zeitschrift (Journal):Lancet Infect Dis. 2020 Feb 19:S1473-3099(19)30626-7. :Seiten (Pages):
Aus der Charité: Maechler F, Schwab F, Hansen S, Behnke M, Golembus J, Kola A, Gastmeier P.Autoren:Biederstädt et al.
Titel:SUMO pathway inhibition targets an aggressive pancreatic cancer subtype.
Zeitschrift (Journal):Gut. 2020 Jan 30. doi: 10.1136/gutjnl-2018-317856. :Seiten (Pages):
Aus der Charité: Schick M, Wirth M, Schneider G, Keller U.
Autoren:Pötsch MS et al.
Titel:MT-102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2020 Feb 17. doi: 10.1002/jcsm.12537. :Seiten (Pages):
Aus der Charité: Ishida J, Palus S, Tschirner A, Döhner W, Anker SD, Springer J.Autoren:Eede P et al.
Titel:Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.
Zeitschrift (Journal):EMBO Rep. 2020 Mar 4;21(3). doi: 10.15252/embr.201948530. :Seiten (Pages):
Aus der Charité: Eede P, Obst J, Benke E, Yvon-Durocher G, Richard BC, Gimber N, Schmoranzer J, Prokop S, Heppner FL.Autoren:Weber D et al.
Titel:Plasma carotenoids, tocopherols and retinol - Association with age in the Berlin Aging Study II.
Zeitschrift (Journal):Redox Biol. 2020 Feb 13;32:101461. :Seiten (Pages):
Aus der Charité: Demuth I, Steinhagen-Thiessen E, Norman K.Autoren:Booker SA et al.
Titel:Presynaptic GABAB receptors functionally uncouple somatostatin interneurons from the active hippocampal network.
Zeitschrift (Journal):Elife. 2020 Feb 19;9:e51156. :Seiten (Pages):
Aus der Charité: Booker SA, Vida I.Autoren:Tizian C et al.
Titel:c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells.
Zeitschrift (Journal):Elife. 2020 Feb 10;9:e52549. :Seiten (Pages):
Aus der Charité: Tizian C, Hölsken O, Cosovanu C, Kofoed-Branzk M, Diefenbach A, Neumann C.Autoren:Hotter B et al.
Titel:Inflammatory and stress markers predicting pneumonia, outcome, and etiology in patients with stroke: Biomarkers for predicting pneumonia, functional outcome, and death after stroke.
Zeitschrift (Journal):Neurol Neuroimmunol Neuroinflamm. 2020 Feb 25;7(3):e692. :Seiten (Pages):
Aus der Charité: Hotter B, Hoffmann S, Ulm L, Meisel C, Meisel A.Autoren:Weilnhammer V et al.
Titel:Psychotic Experiences in Schizophrenia and Sensitivity to Sensory Evidence.
Zeitschrift (Journal):Schizophr Bull. 2020 Feb 24:sbaa003. :Seiten (Pages):
Aus der Charité: Weilnhammer V, Röd L, Eckert AL, Stuke H, Heinz A, Sterzer P.Autoren:Roßberg S et al.
Titel:Orally applied bacterial lysate in infants at risk for atopy does not prevent atopic dermatitis, allergic rhinitis, asthma or allergic sensitization at school age: follow-up of a randomized trial.
Zeitschrift (Journal):Allergy. 2020 Feb 22. doi: 10.1111/all.14247. :Seiten (Pages):
Aus der Charité: Roßberg S, Keller T, Icke K, Keil T, Lau S.
Januar 2020
Autoren:Gidon A et al.
Titel:Dendritic action potentials and computation in human layer 2/3 cortical neurons.
Zeitschrift (Journal):Science. 2020 Jan 3;367(6473):83-87. :Seiten (Pages):
Aus der Charité: Fidzinski P, Bolduan F, Holtkamp M, Vida I, Larkum ME.Autoren:Correll CU et al.
Titel:Metformin add-on vs. antipsychotic switch vs. continued antipsychotic treatment plus healthy lifestyle education in overweight or obese youth with severe mental illness: results from the IMPACT trial.
Zeitschrift (Journal):World Psychiatry. 2020 Feb;19(1):69-80. :Seiten (Pages):
Aus der Charité: Correll CU, Kapoor S.Autoren:Barz MJ et al.
Titel:Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia.
Zeitschrift (Journal):Blood. 2020 Jan 22. doi: 10.1182/blood.2019002499. :Seiten (Pages):
Aus der Charité: Barz MJ, Hof J, Groeneveld-Krentz S, Astrahantseff K, von Stackelberg A.Autoren:Correll CU et al.
Titel:Efficacy and Safety of Lumateperone for Treatment of Schizophrenia: A Randomized Clinical Trial.
Zeitschrift (Journal):Blood. 2020 Jan 22. doi: 10.1182/blood.2019002499. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Ratziu V et al.
Titel:Cenicriviroc Treatment for Adults with Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study.
Zeitschrift (Journal):Hepatology. 2020 Jan 13:10.1002/hep.31108. :Seiten (Pages):
Aus der Charité: Tacke F.Autoren:Schürmann D et al.
Titel:Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial.
Zeitschrift (Journal):Lancet HIV. 2020;S2352-3018(19)30372-8. :Seiten (Pages):
Aus der Charité: Schürmann D, Keicher C, Huser A, Hofmann J.Autoren:Bartels F et al.
Titel:Neuronal autoantibodies associated with cognitive impairment in melanoma patients.
Zeitschrift (Journal):Ann Oncol. 2019 May 1;30(5):823-829. :Seiten (Pages):
Aus der Charité: Bartels F, Stronisch T, Farmer K, Kiecker F, Finke C.Autoren:Stintzing S et al.
Titel:Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial.
Zeitschrift (Journal):Ann Oncol. 2019 Nov 1;30(11):1796-1803. :Seiten (Pages):
Aus der Charité: Stintzing S.Autoren:Petutschnigg J et al.
Titel:Body fat phenotypes and treatment response to spironolactone in ambulatory patients with heart failure and preserved ejection fraction: a post-hoc analysis of the Aldo-DHF trial.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Jan 7:10.1002/ejhf.1723. :Seiten (Pages):
Aus der Charité: Petutschnigg J, Trippel TD, Hashemi D, Pieske B, Edelmann F.Autoren:Scheffel J et al.
Titel:Cold-induced urticarial autoinflammatory syndrome related to factor XII activation.
Zeitschrift (Journal):Nat Commun. 2020 Jan 10;11(1):179. :Seiten (Pages):
Aus der Charité: Scheffel J, Mahnke NA, Wu J, Bonnekoh H, Church MK, Maurer M, Krause K.
Publikationen 2019
Dezember 2019
Autoren:Stahn AC et al.
Titel:Brain Changes in Response to Long Antarctic Expeditions.
Zeitschrift (Journal):N Engl J Med. 2019 Dec 5;381(23):2273-2275. :Seiten (Pages):
Aus der Charité: Stahn AC, Gunga HC.Autoren:Deodhar A et al.
Titel:Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial.
Zeitschrift (Journal):Lancet. 2020 Jan 4;395(10217):53-64. :Seiten (Pages):
Aus der Charité: Poddubnyy D, Sieper J.Autoren:Koche RP et al.
Titel:Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Zeitschrift (Journal):Nat Genet. 2019 Dec 16;10.1038/s41588-019-0547-z. :Seiten (Pages):
Aus der Charité: Helmsauer K, MacArthur IC, Chamorro R, Munoz-Perez N, Dorado Garcia H, Bei Y, Röefzaad C, Bardinet V, Szymansky A, Winkler A, Thole T, Timme N, Fuchs S, Klironomos F, Schmelz K, Künkele A, Hundsdörfer P, Deubzer H, Toedling J, Hertwig F, Eggert A, Schulte JH, Henssen AG.Autoren:Solmi M et al.
Titel:Disparities in cancer screening in people with mental illness across the world versus the general population: prevalence and comparative meta-analysis including 4,717,839 people.
Zeitschrift (Journal):Lancet Psychiatry. 2020 Jan;7(1):52-63. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Stintzing S et al.
Titel:Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial.
Zeitschrift (Journal):Ann Oncol. 2019 Nov 1;30(11):1796-1803. :Seiten (Pages):
Aus der Charité: Stintzing S.Autoren:Möckel M et al.
Titel:Improve Management of acute heart failure with ProcAlCiTonin in EUrope: results of the randomized clinical trial IMPACT EU Biomarkers in Cardiology (BIC) 18.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Dec 12. doi: 10.1002/ejhf.1667. :Seiten (Pages):
Aus der Charité: Möckel M, Slagman AC.Autoren:Pieske B et al.
Titel:Baseline features of the VICTORIA (Vericiguat Global Study in Subjects with Heart Failure with Reduced Ejection Fraction) trial.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Dec;21(12):1596-1604. :Seiten (Pages):
Aus der Charité: Pieske B et al..Autoren:Marg A et al.
Titel:Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
Zeitschrift (Journal):Nat Commun. 2019 Dec 18;10(1):5776. :Seiten (Pages):
Aus der Charité: Marg A, Escobar H, Grunwald SA, Metzler E, Kieshauer J, Pasemann D, Schneider J, Schülke M, Spuler S.Autoren:Ziegler JF et al.
Titel:Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease.
Zeitschrift (Journal):Nat Commun. 2019 Dec 10;10(1):5629. :Seiten (Pages):
Aus der Charité: Ziegler JF, Böttcher C, Letizia M, Yerinde C, Wu H, Freise I, Rodriguez-Sillke Y, Stoyanova AK, Kreis ME, Asbach P, Kunkel D, Priller J, Anagnostopoulos I, Kühl AA, Bojarski C, Glauben R, Siegmund B, Weidinger C.Autoren:Gusic M et al.
Titel:Bi-Allelic UQCRFS1 Variants Are Associated with Mitochondrial Complex III Deficiency, Cardiomyopathy, and Alopecia Totalis.
Zeitschrift (Journal):Am J Hum Genet. 2020 Jan 2;106(1):102-111. :Seiten (Pages):
Aus der Charité: Schottmann G, Lee CY, Morales-Gonzalez S, Schuelke M.
November 2019
Autoren:Middleton PG et al.
Titel:Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.
Zeitschrift (Journal):N Engl J Med. 2019 Nov 7;381(19):1809-1819. :Seiten (Pages):
Aus der Charité: Mall MA.Autoren:van der Heijde D et al.
Titel:Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial.
Zeitschrift (Journal):Lancet. 2019 Dec 7;394(10214):2108-2117. :Seiten (Pages):
Aus der Charité: Sieper J.Autoren:Ahmadi M et al.
Titel:A support programme for secondary prevention in patients with transient ischaemic attack and minor stroke (INSPiRE-TMS): an open-label, randomised controlled trial.
Zeitschrift (Journal):Lancet Neurol. 2019 Nov 7. doi: 10.1016/S1474-4422(19)30369-2. :Seiten (Pages):
Aus der Charité: Ahmadi M, Laumeier I, Ihl T, Steinicke M, Ferse C, Endres M, Schoene M, Kandil FI, Weber JE, Köhler F, Marx P, Audebert HJ.Autoren:Demichev V et al.
Titel:DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput.
Zeitschrift (Journal):Nat Methods. 2019 Nov 25. doi: 10.1038/s41592-019-0638-x. :Seiten (Pages):
Aus der Charité: Ralser M.Autoren:Sankowski R et al.
Titel:Mapping microglia states in the human brain through the integration of high-dimensional techniques.
Zeitschrift (Journal):Nat Neurosci. 2019 Dec;22(12):2098-2110. :Seiten (Pages):
Aus der Charité: Böttcher C, Priller J.Autoren:Primessnig U et al.
Titel:Long-term effects of Na+ /Ca2+ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Nov 24. doi: 10.1002/ejhf.1619. :Seiten (Pages):
Aus der Charité: Primessnig U, Pieske B, Heinzel FR.Autoren:Schewe J et al.
Titel:Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation.
Zeitschrift (Journal):Nat Commun. 2019 Nov 14;10(1):5155. :Seiten (Pages):
Aus der Charité: Schewe J, Seidel E, Forslund S, Marko L, Muller DN, Stölting G, Scholl U.Autoren:Qazi TH et al.
Titel:Niche-mimicking interactions in peptide-functionalized 3D hydrogels amplify mesenchymal stromal cell paracrine effects.
Zeitschrift (Journal):Biomaterials. 2019 Nov 20:119639. :Seiten (Pages):
Aus der Charité: Qazi TH, Duda GN, Geissler S.Autoren:Yildirim F et al.
Titel:Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington's disease.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2019 Dec3;116(49):24840-24851. :Seiten (Pages):
Aus der Charité: Yildirim F.Autoren:Brosig A et al.
Titel:The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches.
Zeitschrift (Journal):Cell Rep. 2019 Nov 12;29(7):2028-2040.e8. :Seiten (Pages):
Aus der Charité: Brosig A, Fuchs J, Ipek F, Kroon C, Schrötter S, Vadhvani M, Ledderose J, Holzhütter HG, Trimbuch T, Gimber N, Schmoranzer J, Rosenmund C, Spahn C, Scheerer P, Szczepek M, Eickholt BJ.
Oktober 2019
Autoren:Maurer M et al.
Titel:Ligelizumab for Chronic Spontaneous Urticaria.
Zeitschrift (Journal):N Engl J Med. 2019 Oct 3;381(14):1321-1332. :Seiten (Pages):
Aus der Charité: Maurer M, Metz M.Autoren:Patzke C et al.
Titel:Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses.
Zeitschrift (Journal):Cell. 2019 Oct 3;179(2):498-513.e22. :Seiten (Pages):
Aus der Charité: Brockmann MM, Grauel MK, Fenske P, Rosenmund C.Autoren:Eckert C et al.
Titel:Improving Stratification for Children With Late Bone Marrow B-Cell Acute Lymphoblastic Leukemia Relapses With Refined Response Classification and Integration of Genetics.
Zeitschrift (Journal):J Clin Oncol. 2019 Oct 23:JCO1901694. doi: 10.1200/JCO.19.01694. :Seiten (Pages):
Aus der Charité: Eckert C, Groeneveld-Krentz S, Kirschner-Schwabe R, Hagedorn N, Chen-Santel C, Astrahantseff K, Eggert A, Henze G, von Stackelberg A.Autoren:Wu H et al.
Titel:Lipid droplet-dependent fatty acid metabolism controls the immune suppressive phenotype of tumor-associated macrophages.
Zeitschrift (Journal):EMBO Mol Med. 2019 Nov 7;11(11):e10698. :Seiten (Pages):
Aus der Charité: Wu H, Rodriguez Sillke Y, Siddiqui S, Treese C, Schmidt F, Friedrich M, Keye J, Kühl AA, Siegmund B, Glauben R.Autoren:Strobel RM et al.
Titel:Reduction of Postoperative Wound Infections by Antiseptica (RECIPE)?: A Randomized Controlled Trial.
Zeitschrift (Journal):Ann Surg. 2019 Oct 9. doi: 10.1097/SLA.0000000000003645. :Seiten (Pages):
Aus der Charité: Strobel RM, Krochmann A, Neumann K, Speichinger F, Hartmann L, Lee LD, Beyer K, Daum S, Kreis ME, Lauscher JC.Autoren:Raccuglia D et al.
Titel:Network-Specific Synchronization of Electrical Slow-Wave Oscillations Regulates Sleep Drive in Drosophila.
Zeitschrift (Journal):Curr Biol. 2019 Nov 4;29(21):3611-3621.e3. :Seiten (Pages):
Aus der Charité: Raccuglia D, Ender A, Heim MM, Laber D, Suárez-Grimalt R, Liotta A, Sigrist SJ, Geiger JRP, Owald D.Autoren:Erdmann S et al.
Titel:CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer.
Zeitschrift (Journal):Theranostics. 2019 Sep 19;9(22):6719-6733. :Seiten (Pages):
Aus der Charité: Erdmann S, Niederstadt L, Koziolek EJ, Gómez JDC, Prasad S, Wagener A, von Hacht JL, Reinicke S, Exner S, Bandholtz S, Beindorff N, Brenner W, Grötzinger C.Autoren:Zidane M et al.
Titel:Decision-Analytic Modeling for Time-Effectiveness of the Sequence of Induction Treatments for Moderate to Severe Plaque Psoriasis.
Zeitschrift (Journal):JAMA Dermatol. 2019 Oct 16. doi: 10.1001/jamadermatol.2019.2941. :Seiten (Pages):
Aus der Charité: Zidane M, Dressler C, Gaskins M, Nast A.Autoren:Penack O et al.
Titel:Association of uric acid levels before start of conditioning with mortality after alloSCT: a prospective, non-interventional study of the EBMT Transplant Complication Working Party.
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Aus der Charité: Penack O, Blau IW.Autoren:Arends CM et al.
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Juli 2019
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Zeitschrift (Journal):Theranostics. 2019 Jan 25;9(3):829-836
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Titel:Widespread microglial activation in multiple system atrophy.
Zeitschrift (Journal):Mov Disord. 2019 Feb 6. doi: 10.1002/mds.27620
Januar 2019
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Titel:Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.
Zeitschrift (Journal):Blood. 2019 Jan 4. doi: 10.1182/blood-2018-05-852822
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Titel:Body weight changes and incidence of cachexia after stroke. J Cachexia Sarcopenia Muscle.
Zeitschrift (Journal):2019 Jan 24. doi: 10.1002/jcsm.12400
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Titel:Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Zeitschrift (Journal):Nat Commun. 2019 Jan 15;10(1):217
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Titel:Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats.
Zeitschrift (Journal):Mol Psychiatry. 2019 Jan 28. doi: 10.1038/s41380-019-0356-x
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Titel:Bio-Orthogonal Chemistry and Reloadable Biomaterial Enable Local Activation of Antibiotic Prodrugs and Enhance Treatments against Staphylococcus aureus Infections.
Zeitschrift (Journal):ACS Cent Sci. 2018 Dec 26;4(12):1624-1632
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Titel:Cardiac contractility modulation improves long-term survival and hospitalizations in heart failure with reduced ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Jan 16. doi: 10.1002/ejhf.1374
Autoren:Houtman J, Freitag K, Gimber N, Schmoranzer J, Heppner FL, Jendrach M.
Titel:Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3.
Zeitschrift (Journal):EMBO J. 2019 Feb 15;38(4)
Autoren:Çakmak-Görür N et al.
Titel:Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies.
Zeitschrift (Journal):Leukemia. 2019 Jan 3. doi: 10.1038/s41375-018-0330-7
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Titel:Use of a Repositionable and Fully Retrievable Aortic Valve in Routine Clinical Practice: The RESPOND Study and RESPOND Extension Cohort.
Zeitschrift (Journal):JACC Cardiovasc Interv. 2019 Jan 14;12(1):38-49
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Titel:Avelumab in patients with previously treated metastatic melanoma: phase 1b results from the JAVELIN Solid Tumor trial.
Zeitschrift (Journal):J Immunother Cancer. 2019 Jan 16;7(1):12