Ausgewählte Publikationen der Charité
Die Wissenschaftlerinnen und Wissenschaftler der Charité veröffentlichen mehr als 4.000 Fachpublikationen im Jahr.
Hier stellen wir Ihnen pro Monat zehn ausgewählte Publikationen vor.
Sie befinden sich hier:
Open Access bedeutet offener Zugang zu wissenschaftlichen Forschungsergebnissen: Wissenschaftliche Publikationen sind weltweit öffentlich und kostenfrei im Internet zugänglich und können von jedermann im Rahmen der guten wissenschaftlichen Praxis gelesen, kopiert, gedruckt, verbreitet und elektronisch durchsucht werden. (Weitere Informationen der Medizinischen Bibliothek)
Open Code markiert Publikationen mit offen geteilter Analysesoftware. Voraussetzung ist nach den Kriterien des BIH Quest Centers ein selbst geschriebener oder individuell angepasster Code, auf den in der Publikation verwiesen wird und der kostenlos und ohne Auflagen zugänglich ist.
Open Data markiert Publikationen mit offen geteilten Daten. Voraussetzungen für Open Data sind die freie Verfügbarkeit der Originaldaten, maschinenlesbares Format und ein eindeutiger Verweis auf Open Data im Volltext nach den Kriterien des BIH Quest Centers.
Publikationen 2020
Dezember 2020
Autoren:Veenvliet JV et al.
Titel:Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites.
Zeitschrift (Journal):Science. 2020 Dec 11;370(6522):eaba4937. :Seiten (Pages):
Aus der Charité: Herrmann BG.
Autoren:Trump S et al.
Titel:Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19.
Zeitschrift (Journal):Nat Biotechnol. 2020 Dec 24. doi: 10.1038/s41587-020-00796-1. :Seiten (Pages):
Aus der Charité: Trump S, Lukassen S, Anker MS, Chua RL, Liebig J, Thürmann L, Corman VM, Loske J, Krieger T, Hennig BP, Messingschlager M, Pott F, Kazmierski J, Twardziok S, Albrecht JP, Eils J, Hadzibegovic S, Lena A, Heidecker B, Bürgel T, Steinfeldt J, Goffinet C, Kurth F, Witzenrath M, Ishaque N, Sander LE, Drosten C, Eils R, Conrad C, Landmesser U, Lehmann I.Autoren:Abraham WT et al.
Titel:Effect of empagliflozin on exercise ability and symptoms in heart failure patients with reduced and preserved ejection fraction, with and without type 2 diabetes.
Zeitschrift (Journal):Eur Heart J. 2020 Dec 22:ehaa943. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Meinhardt J et al.
Titel:Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.
Zeitschrift (Journal):Nat Neurosci. 2020 Nov 30. doi: 10.1038/s41593-020-00758-5. :Seiten (Pages):
Aus der Charité: Meinhardt J, Radke J, Dittmayer C, Mothes R, Schneider J, Brünink S, Greuel S, Lehmann M, Hassan O, Aschman T, Schumann E, Chua RL, Conrad C, Eils R, Stenzel W, Windgassen M, Rößler L, Goebel HH, Martin H, Scheibe F, Körtvélyessy P, Siegmund B, Kühl AA, Elezkurtaj S, Horst D, Oesterhelweg L, Tsokos M, Drosten C, Corman VM, Radbruch H, Heppner FL.Autoren:Kraushar ML et al.
Titel:Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.
Zeitschrift (Journal):Mol Cell. 2020 Dec 17:S1097-2765(20)30837-6. :Seiten (Pages):
Aus der Charité: Kraushar ML, Krupp F, Turko P, Ambrozkiewicz MC, Sprink T, Schaub T, Münster-Wandowski A, Bürger J, Yamamoto H, Tarabykin V, Vida I, Spahn CMT.
Autoren:Piepoli MF et al.
Titel:OUTSTEP-HF: randomised controlled trial comparing short-term effects of sacubitril/valsartan versus enalapril on daily physical activity in patients with chronic heart failure with reduced ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Dec 13. doi: 10.1002/ejhf.2076. :Seiten (Pages):
Aus der Charité: Edelmann F.Autoren:Anker SD et al.
Titel:Baseline Characteristics of Patients with Heart Failure with Preserved Ejection Fraction in the EMPEROR-Preserved Trial.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Nov 29. doi: 10.1002/ejhf.2064. :Seiten (Pages):
Aus der Charité: Anker SD.
Autoren:Grinat J et al.
Titel:The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Zeitschrift (Journal):Nat Commun. 2020 Dec 21;11(1):6422. :Seiten (Pages):
Aus der Charité: Heuberger J.
Autoren:Pietzner M et al.
Titel:Genetic architecture of host proteins involved in SARS-CoV-2 infection.
Zeitschrift (Journal):Nat Commun. 2020 Dec 16;11(1):6397. :Seiten (Pages):
Aus der Charité: Ralser M, Langenberg C.Autoren:Loyal L et al.
Titel:SLAMF7 and IL-6R define distinct cytotoxic versus helper memory CD8+ T cells.
Zeitschrift (Journal):Nat Commun. 2020 Dec 11;11(1):6357. :Seiten (Pages):
Aus der Charité: Loyal L, Warth S, Jürchott K, Nikolaou C, Nienen M, Durlanik S, Kruse B, Frentsch M, Sabat R, Wolk K, Thiel A.
November 2020
Autoren:Clément K et al.
Titel:Setmelanotide POMC and LEPR Phase 3 Trial Investigators. Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.
Zeitschrift (Journal):Lancet Diabetes Endocrinol. 2020 Dec;8(12):960-970. :Seiten (Pages):
Aus der Charité: Puder L, Kühnen P.Autoren:Anker SD et al.
Titel:EMPEROR-Reduced Trial Committees and Investigators. Effect of Empagliflozin on Cardiovascular and Renal Outcomes in Patients With Heart Failure by Baseline Diabetes Status - Results from the EMPEROR-Reduced Trial.
Zeitschrift (Journal):Circulation. 2020 Nov 11. doi: 10.1161/CIRCULATIONAHA.120.051824. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Guendel F et al.
Titel:Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues.
Zeitschrift (Journal):Immunity. 2020 Nov 17;53(5):1015-1032.e8. :Seiten (Pages):
Aus der Charité: Guendel F, Kofoed-Branzk M, Gronke K, Tizian C, Witkowski M, Brachs S, Mashreghi MF, Diefenbach A.Autoren:Tosti L et al.
Titel:Single nucleus and in situ RNA sequencing reveals cell topographies in the human pancreas.
Zeitschrift (Journal):Gastroenterology. 2020 Nov 16:S0016-5085(20)35399-3. :Seiten (Pages):
Aus der Charité: Tosti L, Debnath O, Tiesmeyer S, Trefzer T, Ten FW, Lukassen S, Kühl AA, Spieckermann S, Ishaque N, Eils R, Conrad C.Autoren:McVey MJ et al.
Titel:Platelet Extracellular Vesicles mediate Transfusion-related Acute Lung Injury by imbalancing the Sphingolipid Rheostat.
Zeitschrift (Journal):Blood. 2020 Nov 24:blood.2020005985. :Seiten (Pages):
Aus der Charité: Weidenfeld S, Tabuchi A, Simmons S, Kuebler W.Autoren:Reimann M et al.
Titel:Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Zeitschrift (Journal):Blood. 2020 Nov 24:blood.2020005244. :Seiten (Pages):
Aus der Charité: Reimann M, Schrezenmeier JF, Richter-Pechanska P, Dolnik A, Hick TP, Schleich K, Cai X, Fan DNY, Masswig S, Denker S, Busse A, Gätjens-Sanchez AM, Bullinger L.Autoren:Dejaco C et al.
Titel:Influence of COVID-19 pandemic on decisions for the management of people with inflammatory rheumatic and musculoskeletal diseases: a survey among EULAR countries.
Zeitschrift (Journal):Ann Rheum Dis. 2020 Nov 6:annrheumdis-2020-218697. :Seiten (Pages):
Aus der Charité: Buttgereit F.Autoren:Holstein J et al.
Titel:Immunophenotyping in pemphigus reveals a Th17/Tfh17-dominated immune response promoting desmoglein1/3-specific autoantibody production.
Zeitschrift (Journal):J Allergy Clin Immunol. 2020 Nov 19:S0091-6749(20)31624-9. :Seiten (Pages):
Aus der Charité: Solimani F, Meier K, Ghoreschi K.Autoren:Anker MS et al.
Titel:Ventricular tachycardia, premature ventricular contractions, and mortality in unselected patients with lung, colon, or pancreatic cancer: a prospective study.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Nov 22. doi: 10.1002/ejhf.2059. :Seiten (Pages):
Aus der Charité: Anker MS, Riess H, Eucker J, Haverkamp W, Landmesser U, Anker SD.Autoren:Lebenheim L et al.
Titel:A novel giant non-cholinergic striatal interneuron restricted to the ventrolateral striatum coexpresses Kv3.3 potassium channel, parvalbumin, and the vesicular GABA transporter.
Zeitschrift (Journal):Mol Psychiatry. 2020 Nov 14. doi: 10.1038/s41380-020-00948-4. :Seiten (Pages):
Aus der Charité: Lebenheim L, Booker SA, Derst C, Weiss T, Wagner F, Gruber C, Vida I, Veh RW.
Oktober 2020
Autoren:M Real F et al.
Titel:The mole genome reveals regulatory rearrangements associated with adaptive intersexuality.
Zeitschrift (Journal):Science. 2020 Oct 9;370(6513):208-214. :Seiten (Pages):
Aus der Charité: M Real F, Schöpflin R, Schindler M, Mundlos S, Lupiáñez DG.Autoren:Kreye J et al.
Titel:A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Zeitschrift (Journal):Cell. 2020 Sep 23:S0092-8674(20)31246-0. :Seiten (Pages):
Aus der Charité: Kreye J, Reincke SM, Kornau HC, Sánchez-Sendin E, Corman VM, Höltje M, Stöffler L, von Wardenburg N, van Hoof S, Homeyer MA, Hoffmann J, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Müller MA, Drosten C, Wendisch D, Sander LE, Prüss H.
Autoren:Roemhild A et al.
Titel:Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial.
Zeitschrift (Journal):BMJ. 2020 Oct 21;371:m3734. :Seiten (Pages):
Aus der Charité: Roemhild A, Otto NM, Moll G, Abou-El-Enein M, Kaiser D, Bold G, Schachtner T, Choi M, Oellinger R, Landwehr-Kenzel S, Juerchott K, Sawitzki B, Giesler C, Sefrin A, Beier C, Wagner DL, Schlickeiser S, Streitz M, Schmueck-Henneresse M, Amini L, Babel N, Volk HD, Reinke P.Autoren:Leistner DM et al.
Titel:Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study.
Zeitschrift (Journal):Eur Heart J. 2020 Oct 1;41(37):3549-3560. :Seiten (Pages):
Aus der Charité: Leistner DM, Kränkel N, Meteva D, Abdelwahed YS, Seppelt C, Stähli BE, Skurk C, Lauten A, Mochmann HC, Fröhlich G, Rauch-Kröhnert U, Flores E, Riedel M, Sieronski L, Kia S, Strässler E, Haghikia A, Dirks F, Steiner JK, Mueller DN, Volk HD, Klotsche J, Landmesser U.Autoren:Fujikura K et al.
Titel:Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic KLF4 mutations predominantly in low-grade regions.
Zeitschrift (Journal):Gut. 2020 Oct 7:gutjnl-2020-321217. :Seiten (Pages):
Aus der Charité: Felsenstein M.Autoren:Schoon J et al.
Titel:Metal-Specific Biomaterial Accumulation in Human Peri-Implant Bone and Bone Marrow.
Zeitschrift (Journal):Adv Sci (Weinh). 2020 Aug 3;7(20):2000412. :Seiten (Pages):
Aus der Charité: Schoon J, Rakow A, Ort MJ, Jacobi D, Reinke S, Perka C, Duda GN, Geissler S.Autoren:Cohen SB et al.
Titel:Safety profile of upadacitinib in rheumatoid arthritis: integrated analysis from the SELECT phase III clinical programme.
Zeitschrift (Journal):Ann Rheum Dis. 2020 Oct 28:annrheumdis-2020-218510. :Seiten (Pages):
Aus der Charité: Burmester GR.Autoren:Zuraw B et al.
Titel:Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: a randomized, double-blind, placebo-controlled phase 3 trial.
Zeitschrift (Journal):J Allergy Clin Immunol. 2020 Oct 21:S0091-6749(20)31484-6. :Seiten (Pages):
Aus der Charité: Maurer M.Autoren:Koehler J et al.
Titel:Telemonitoring in patients with chronic heart failure and moderate depressed symptoms: results of the Telemedical Interventional Monitoring in Heart Failure (TIM-HF) study.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Oct 15. doi: 10.1002/ejhf.2025. :Seiten (Pages):
Aus der Charité: Koehler J, Stengel A, Hofmann T, Koehler K, Rose M, Deckwart O, Anker SD, Koehler F.Autoren:Ballhausen A et al.
Titel:Phase I study of everolimus, letrozole, and trastuzumab in patients with hormone receptor-positive metastatic breast cancer or other solid tumors.
Zeitschrift (Journal):Clin Cancer Res. 2020 Oct 28:clincanres.2878.2020. :Seiten (Pages):
Aus der Charité: Ballhausen A.
September 2020
Autoren:Ostendorf L et al.
Titel:Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus.
Zeitschrift (Journal):N Engl J Med. 2020 Sep 17;383(12):1149-1155. :Seiten (Pages):
Aus der Charité: Ostendorf L, Burns M, Durek P, Heinz GA, Heinrich F, Garantziotis P, Enghard P, Richter U, Biesen R, Schneider U, Knebel F, Burmester G, Radbruch A, Mei HE, Mashreghi MF, Hiepe F, Alexander T.Autoren:Schweizer L et al.
Titel:Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity.
Zeitschrift (Journal):Acta Neuropathol. 2020 Sep 14. doi: 10.1007/s00401-020-02218-7. :Seiten (Pages):
Aus der Charité: Schweizer L, Thierfelder F, Wessels L, Misch M, Kim HY, Jödicke R, Teichmann D, Kaul D, Kahn J, Bockmayr M, Vajkoczy P, Heppner FL, Capper D, Schöler A, Koch A.Autoren:Verner G et al.
Titel:Maternal Psychological Resilience During Pregnancy and Newborn Telomere Length: A Prospective Study.
Zeitschrift (Journal):Am J Psychiatry. 2020 Sep 11:appiajp202019101003. :Seiten (Pages):
Aus der Charité: Verner G, Buss C, Entringer S.Autoren:Bogdanow B et al.
Titel:Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis.
Zeitschrift (Journal):Nat Commun. 2020 Sep 24;11(1):4845. :Seiten (Pages):
Aus der Charité: Schmidt M, Weisbach H, Gruska I, Vetter B, Selbach M, Hagemeier C, Wiebusch L.Autoren:Amini L et al.
Titel:CRISPR-Cas9-Edited Tacrolimus-Resistant Antiviral T Cells for Advanced Adoptive Immunotherapy in Transplant Recipients.
Zeitschrift (Journal):Mol Ther. 2020 Sep 8:S1525-0016(20)30468-8. :Seiten (Pages):
Aus der Charité: Amini L, Wagner DL, Rössler U, Zarrinrad G, Wagner LF, Vollmer T, Wendering DJ, Kornak U, Volk HD, Reinke P, Schmueck-Henneresse M.Autoren:Klotz-Noack K et al.
Titel:SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells.
Zeitschrift (Journal):Cell Rep. 2020 Sep 22;32(12):108184. :Seiten (Pages):
Aus der Charité:Klotz-Noack K, Klinger B, Bublitz N, Uhlitz F, Riemer P, Lüthen M, Sell T, Kasack K, Gastl B, Ispasanie SSS, Simon T, Horst D, Blüthgen N, Schäfer R, Morkel M, Sers C.Autoren:Wang Y et al.
Titel:Selenium deficiency is linearly associated with hypoglycemia in healthy adults.
Zeitschrift (Journal):Redox Biol. 2020 Sep 1;37:101709. :Seiten (Pages):
Aus der Charité: Rijntjes E, Schomburg L.Autoren:Knaak C et al.
Titel:Treatment and Mortality of Hemophagocytic Lymphohistiocytosis in Adult Critically Ill Patients: A Systematic Review With Pooled Analysis.
Zeitschrift (Journal):Crit Care Med. 2020 Nov;48(11):e1137-e1146. :Seiten (Pages):
Aus der Charité: Knaak C, Schuster FS, Nyvlt P, Spies C, Keh D, Lachmann G.Autoren:Puthucheary ZA et al.
Titel:Implications for post critical illness trial design: sub-phenotyping trajectories of functional recovery among sepsis survivors.
Zeitschrift (Journal):Crit Care. 2020 Sep 25;24(1):577. :Seiten (Pages):
Aus der Charité: Heintze C, Neumann K, Wollersheim T, Schmidt KFR.Autoren:Scholz J et al.
Titel:Vitamin A controls the allergic response through T follicular helper cell as well as plasmablast differentiation.
Zeitschrift (Journal):Allergy. 2020 Sep 7. doi: 10.1111/all.14581. :Seiten (Pages):
Aus der Charité: Scholz J, Worm M, Heine G.
August 2020
Autoren:Sadik A et al.
Titel:IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Zeitschrift (Journal):Cell. 2020 Sep 3;182(5):1252-1270.e34. :Seiten (Pages):
Aus der Charité: Ishaque N, Trump S.Autoren:Schulte-Schrepping J et al.
Titel:Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
Zeitschrift (Journal):Cell. 2020 Aug 5:S0092-8674(20)30992-2. :Seiten (Pages):
Aus der Charité: Paclik D, Schlickeiser S, Brumhard S, Wendisch D, Conrad C, Kunkel D, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, Müller-Redetzky H, Heim KM, Machleidt F, Uhrig A, Bosquillon de Jarcy L, Jürgens L, Stegemann M, Glösenkamp CR, Volk HD, Goffinet C, Georg P, Schneider M, Dang-Heine C, Neuwinger N, Kappert K, Tauber R, Corman V, Meisel C, Witzenrath M, Drosten C, Suttorp N, von Kalle C, Kurth F, Sawitzki B, Sander LE.Autoren:Grünwald V et al.
Titel:Randomized Comparison of Pazopanib and Doxorubicin as First-Line Treatment in Patients With Metastatic Soft Tissue Sarcoma Age 60 Years or Older: Results of a German Intergroup Study.
Zeitschrift (Journal):J Clin Oncol. 2020 Aug 24:JCO2000714. :Seiten (Pages):
Aus der Charité: Kunitz A.Autoren:Kresoja KP et al.
Titel:Transcatheter tricuspid valve repair in the setting of heart failure with preserved or reduced left ventricular ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Aug 2. doi: 10.1002/ejhf.1975. :Seiten (Pages):
Aus der Charité: Lauten A, Alushi B, Stangl K, Landmesser U.Autoren:Correll CU et al.
Titel:Effects of Olanzapine Combined With Samidorphan on Weight Gain in Schizophrenia: A 24-Week Phase 3 Study.
Zeitschrift (Journal):Am J Psychiatry. 2020 Aug 14:appiajp202019121279. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Sattler A et al.
Titel:SARS-CoV-2 specific T-cell responses and correlations with COVID-19 patient predisposition.
Zeitschrift (Journal):J Clin Invest. 2020 Aug 24:140965. :Seiten (Pages):
Aus der Charité: Sattler A, Angermair S, Stockmann H, Heim KM, Khadzhynov D, Treskatsch S, Halleck F, Kreis ME, Kotsch K.Autoren:Erfinanda L et al.
Titel:Estrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation.
Zeitschrift (Journal):Eur Respir J. 2020 Aug 6:2000921. :Seiten (Pages):
Aus der Charité: Erfinanda L, Kohse F, Gallo K, Preissner R, Kuebler WM.Autoren:von Haehling S et al.
Titel:Muscle wasting as an independent predictor of survival in patients with chronic heart failure.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2020 Aug 6. doi: 10.1002/jcsm.12603. :Seiten (Pages):
Aus der Charité: Anker MS, Doehner W, Anker SD.Autoren:Daneshgar A et al.
Titel:The human liver matrisome - Proteomic analysis of native and fibrotic human liver extracellular matrices for organ engineering approaches.
Zeitschrift (Journal):Biomaterials. 2020 Oct;257:120247. :Seiten (Pages):
Aus der Charité: Daneshgar A, Tang P, Arnold A, Pohl J, Moosburner S, Raschzok N, Bahra M, Pratschke J, Sauer IM, Hillebrandt KH.Autoren:Krenzien F et al.
Titel:The ILLS Laparoscopic Liver Surgery Fellow Skills Curriculum.
Zeitschrift (Journal):Ann Surg. 2020 Aug 21. doi: 10.1097/SLA.0000000000004175. :Seiten (Pages):
Aus der Charité: Krenzien F, Schöning W, Brunnbauer P, Benzing C, Öllinger R, Biebl M, Bahra M, Raschzok N, Schmelzle M, Pratschke J.
Juli 2020
Autoren:Burmester GR et al.
Titel:Continuing versus tapering glucocorticoids after achievement of low disease activity or remission in rheumatoid arthritis (SEMIRA): a double-blind, multicentre, randomised controlled trial.
Zeitschrift (Journal):Lancet. 2020 Jul 25;396(10246):267-276. :Seiten (Pages):
Aus der Charité: Burmester GR, Buttgereit F.Autoren:Braun J et al.
Titel:SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19.
Zeitschrift (Journal):Nature. 2020 Jul 29. doi: 10.1038/s41586-020-2598-9. :Seiten (Pages):
Aus der Charité: Braun J, Loyal L, Frentsch M, Wendisch D, Georg P, Kurth F, Hippenstiel S, Dingeldey M, Kruse B, Fauchere F, Baysal E, Mangold M, Henze L, Lauster R, Mall MA, Beyer K, Röhmel J, Demuth I, Müller MA, Hocke A, Witzenrath M, Suttorp N, Drosten C, Corman VM, Sander LE, Thiel A.Autoren:Mühlemann B at al.
Titel:Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age.
Zeitschrift (Journal):Science. 2020 Jul 24;369(6502):eaaw8977. :Seiten (Pages):
Aus der Charité: Mühlemann B, Drosten C, Jones TC.Autoren:Lang S et al.
Titel:Intestinal Virome Signature Associated With Severity of Nonalcoholic Fatty Liver Disease.
Zeitschrift (Journal):Gastroenterology. 2020 Jul 8:S0016-5085(20)34923-4. :Seiten (Pages):
Aus der Charité: Demir M, Roderburg C, Tacke F.Autoren:Fan Y et al.
Titel:TWIST1 Drives Smooth Muscle Cell Proliferation in Pulmonary Hypertension via Loss of GATA-6 and BMPR2.
Zeitschrift (Journal):Am J Respir Crit Care Med. 2020 Jul 21. doi: 10.1164/rccm.201909-1884OC. :Seiten (Pages):
Aus der Charité: Solymosi P, Kuebler WM.Autoren:Graeber SY et al.
Titel:Comparison of Organoid Swelling and in vivo Biomarkers of CFTR Function to Determine Effects of Lumacaftor-ivacaftor in Patients with Cystic Fibrosis Homozygous for the F508del Mutation.
Zeitschrift (Journal):Am J Respir Crit Care Med. 2020 Jul 20. doi: 10.1164/rccm.202004-1200LE. :Seiten (Pages):
Aus der Charité: Graeber SY, Mall MA.Autoren:Papadopoulos IN et al.
Titel:Dynamic conjugate F-SHARP microscopy.
Zeitschrift (Journal):Light Sci Appl. 2020 Jun 30;9:110. :Seiten (Pages):
Aus der Charité: Papadopoulos IN, Judkewitz B.Autoren:Endisch C et al.
Titel:Hypoxic-Ischemic Encephalopathy Evaluated by Brain Autopsy and Neuroprognostication After Cardiac Arrest.
Zeitschrift (Journal):JAMA Neurol. 2020 Jul 20:e202340. :Seiten (Pages):
Aus der Charité: Endisch C, Kenda M, Streitberger KJ, Stenzel W, Storm C, Ploner CJ, Leithner C.Autoren:Schleich K et al.
Titel:H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients.
Zeitschrift (Journal):Nat Commun. 2020 Jul 20;11(1):3651. :Seiten (Pages):
Aus der Charité: Schleich K, Kase J, Dörr JR, Bhattacharya A, Wailes EM, Fan DNY, Milanovic M, Lau A, Lenze D, Hummel M, Reimann M, Lee S, Schmitt CA.Autoren:Li N et al.
Titel:A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder.
Zeitschrift (Journal):Nat Commun. 2020 Jul 3;11(1):3364. :Seiten (Pages):
Aus der Charité: Li N, Al-Fatly B, Kühn AA, Horn A.
Juni 2020
Autoren:Kurth T et al.
Titel:Association of Migraine With Aura and Other Risk Factors With Incident Cardiovascular Disease in Women.
Zeitschrift (Journal):JAMA. 2020 Jun 9;323(22):2281-2289. :Seiten (Pages):
Aus der Charité: Kurth T.Autoren:Chua RL et al.
Titel:COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis.
Zeitschrift (Journal):Nat Biotechnol. 2020 Jun 26. doi: 10.1038/s41587-020-0602-4. :Seiten (Pages):
Aus der Charité: Chua RL, Lukassen S, Trump S, Hennig BP, Wendisch D, Pott F, Debnath O, Thürmann L, Kurth F, Kazmierski J, Twardziok S, Schneider S, Machleidt F, Müller-Redetzky H, Krannich A, Schmidt S, Balzer F, Liebig J, Loske J, Suttorp N, Eils J, Ishaque N, von Kalle C, Hocke A, Witzenrath M, Goffinet C, Drosten C, Lehmann I, Conrad C, Sander LE, Eils R.Autoren:Ercu M et al.
Titel:Phosphodiesterase 3A and Arterial Hypertension.
Zeitschrift (Journal):Circulation. 2020 Jul 14;142(2):133-149. :Seiten (Pages):
Aus der Charité: Markó L, Schächterle C, Tsvetkov D, Cui Y, Bartolomaeus TUP, Hübner N, Illas RM, Anistan YM, Forslund SK, Kamer I, Müller DN, Gollasch M, Bähring S, Luft FC.Autoren:Jenning M et al.
Titel:Bacterial citrullinated epitopes generated by Porphyromonas gingivalis infection-a missing link for ACPA production.
Zeitschrift (Journal):Ann Rheum Dis. 2020 Jun 12:annrheumdis-2019-216919. :Seiten (Pages):
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Titel:Phenotype and risk factors of venom-induced anaphylaxis: a case-control study of the European Anaphylaxis Registry.
Zeitschrift (Journal):J Allergy Clin Immunol. 2020 Jun 22:S0091-6749(20)30838-1. :Seiten (Pages):
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Titel:Drug allergy to CFTR modulator therapy associated with lumacaftor-specific CD4+ T lymphocytes.
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Titel:Clozapine modulates retinoid homeostasis in human brain and normalizes serum retinoic acid deficit in patients with schizophrenia.
Zeitschrift (Journal):Mol Psychiatry. 2020 Jun 2. doi: 10.1038/s41380-020-0791-8. :Seiten (Pages):
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Titel:Epilepsy-causing STX1B mutations translate altered protein functions into distinct phenotypes in mouse neurons.
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Titel:GFR in Healthy Aging: an Individual Participant Data Meta-Analysis of Iohexol Clearance in European Population-Based Cohorts.
Zeitschrift (Journal):J Am Soc Nephrol. 2020 Jul;31(7):1602-1615. :Seiten (Pages):
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Titel:Neutrophil Gelatinase-Associated Lipocalin Protects from ANCA-Induced GN by Inhibiting TH17 Immunity.
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Aus der Charité: Schreiber A, Rousselle A, Klocke J, Bachmann S, Popovic S, Bontscho J, Schmidt-Ott KM, Siffrin V, Jerke U, Ashraf MI, Kettritz R.
Mai 2020
Autoren:Sawitzki B et al.
Titel:Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
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Titel:Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells.
Zeitschrift (Journal):Cell. 2020 May 28;181(5):1080-1096.e19. :Seiten (Pages):
Aus der Charité: Schaupp L, Rogell L, Kofoed-Branzk M, Guendel F, Diefenbach A.Autoren:Solmi M et al.
Titel:Safety of 80 antidepressants, antipsychotics, anti-attention-deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta-review of 78 adverse effects.
Zeitschrift (Journal):World Psychiatry. 2020 Jun;19(2):214-232. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Piccininni M et al.
Titel:Use of all cause mortality to quantify the consequences of covid-19 in Nembro, Lombardy: descriptive study.
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Titel:Investigation of a COVID-19 outbreak in Germany resulting from a single travel-associated primary case: a case series.
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Titel:Obesity and weight loss are inversely related to mortality and cardiovascular outcome in prediabetes and type 2 diabetes: data from the ORIGIN trial.
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Titel:Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages.
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Titel:Canakinumab for Treatment of Adult-Onset Still's Disease to Achieve Reduction of Arthritic Manifestation (CONSIDER): phase II, randomised, double-blind, placebo-controlled, multicentre, investigator-initiated trial.
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Titel:PGE₂ deficiency predisposes to anaphylaxis by causing mast cell hyper-responsiveness.
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Titel:Rationale and Study Design of OUTSTEP-HF: A Randomized Controlled Study to Assess the Effect of Sacubitril/Valsartan and Enalapril on Physical Activity measured by Accelerometry in Patients with Heart Failure with Reduced Ejection Fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2020 May 28. doi: 10.1002/ejhf.1919. :Seiten (Pages):
Aus der Charité: Edelmann F.
April 2020
Autoren:Wölfel R et al.
Titel:Virological assessment of hospitalized patients with COVID-2019.
Zeitschrift (Journal):Nature. 2020 Apr 1. doi: 10.1038/s41586-020-2196-x. :Seiten (Pages):
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Titel:A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection.
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Titel:Functional consequences of metabolic zonation in murine livers: New insights for an old story.
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Titel:Minimal clinically important difference in quality of life scores for patients with heart failure and reduced ejection fraction.
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Titel:RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
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Titel:The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc.
Zeitschrift (Journal):Mol Psychiatry. 2020 Apr 6. doi: 10.1038/s41380-020-0714-8. :Seiten (Pages):
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Titel:Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.
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Titel:Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway.
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Aus der Charité: Nitzan N, Beed P, Oldani S, Tukker JJ, Schmitz D.Autoren:Basu Roy R et al.
Titel:Performance of immune-based and microbiological tests in children with TB meningitis in Europe - a multi-center Paediatric Tuberculosis Network European Trials Group (ptbnet) study.
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Titel:SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells.
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März 2020
Autoren:Bockstahler M et al.
Titel:Heart-Specific Immune Responses in an Animal Model of AutoimmuneRelated Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation.
Zeitschrift (Journal):Circulation. 2020 Mar 12. doi: 10.1161/CIRCULATIONAHA.119.043171. :Seiten (Pages):
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Titel:Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity.
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Titel:Complement deposition at the neuromuscular junction in seronegative myasthenia gravis.
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Titel:Association of Magnetoencephalographically Measured High-Frequency Oscillations in Visual Cortex With Circuit Dysfunctions in Local and Large-scale Networks During Emerging Psychosis.
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Aus der Charité: Grent-'t-Jong T, Uhlhaas PJ.Autoren:Ullah I et al.
Titel:Adult Tissue Extracellular Matrix Determines Tissue Specification of Human iPSC-Derived Embryonic Stage Mesodermal Precursor Cells.
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Titel:Evaluation of high-sensitivity C-reactive protein and uric acid in vericiguat-treated patients with heart failure with reduced ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Mar 25. doi: 10.1002/ejhf.1787. :Seiten (Pages):
Aus der Charité: Pieske B.Autoren:Anker MS et al.
Titel:Increased resting heart rate and prognosis in treatment-naïve unselected cancer patients: results from a prospective observational study.
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Titel:Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming.
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Titel:New method for rapid and dynamic quantification of elastase activity on sputum neutrophils from patients with cystic fibrosis using flow cytometry.
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Titel:SuperCYPsPred-a web server for the prediction of cytochrome activity.
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Februar 2020
Autoren:Maechler F et al.
Titel:Contact isolation versus standard precautions to decrease acquisition of extended-spectrum β-lactamase-producing Enterobacterales in non-critical care wards: a cluster-randomised crossover trial.
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Titel:SUMO pathway inhibition targets an aggressive pancreatic cancer subtype.
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Titel:MT-102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2020 Feb 17. doi: 10.1002/jcsm.12537. :Seiten (Pages):
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Titel:Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.
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Titel:Plasma carotenoids, tocopherols and retinol - Association with age in the Berlin Aging Study II.
Zeitschrift (Journal):Redox Biol. 2020 Feb 13;32:101461. :Seiten (Pages):
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Titel:Presynaptic GABAB receptors functionally uncouple somatostatin interneurons from the active hippocampal network.
Zeitschrift (Journal):Elife. 2020 Feb 19;9:e51156. :Seiten (Pages):
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Titel:c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells.
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Aus der Charité: Tizian C, Hölsken O, Cosovanu C, Kofoed-Branzk M, Diefenbach A, Neumann C.Autoren:Hotter B et al.
Titel:Inflammatory and stress markers predicting pneumonia, outcome, and etiology in patients with stroke: Biomarkers for predicting pneumonia, functional outcome, and death after stroke.
Zeitschrift (Journal):Neurol Neuroimmunol Neuroinflamm. 2020 Feb 25;7(3):e692. :Seiten (Pages):
Aus der Charité: Hotter B, Hoffmann S, Ulm L, Meisel C, Meisel A.Autoren:Weilnhammer V et al.
Titel:Psychotic Experiences in Schizophrenia and Sensitivity to Sensory Evidence.
Zeitschrift (Journal):Schizophr Bull. 2020 Feb 24:sbaa003. :Seiten (Pages):
Aus der Charité: Weilnhammer V, Röd L, Eckert AL, Stuke H, Heinz A, Sterzer P.Autoren:Roßberg S et al.
Titel:Orally applied bacterial lysate in infants at risk for atopy does not prevent atopic dermatitis, allergic rhinitis, asthma or allergic sensitization at school age: follow-up of a randomized trial.
Zeitschrift (Journal):Allergy. 2020 Feb 22. doi: 10.1111/all.14247. :Seiten (Pages):
Aus der Charité: Roßberg S, Keller T, Icke K, Keil T, Lau S.
Januar 2020
Autoren:Gidon A et al.
Titel:Dendritic action potentials and computation in human layer 2/3 cortical neurons.
Zeitschrift (Journal):Science. 2020 Jan 3;367(6473):83-87. :Seiten (Pages):
Aus der Charité: Fidzinski P, Bolduan F, Holtkamp M, Vida I, Larkum ME.Autoren:Correll CU et al.
Titel:Metformin add-on vs. antipsychotic switch vs. continued antipsychotic treatment plus healthy lifestyle education in overweight or obese youth with severe mental illness: results from the IMPACT trial.
Zeitschrift (Journal):World Psychiatry. 2020 Feb;19(1):69-80. :Seiten (Pages):
Aus der Charité: Correll CU, Kapoor S.Autoren:Barz MJ et al.
Titel:Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia.
Zeitschrift (Journal):Blood. 2020 Jan 22. doi: 10.1182/blood.2019002499. :Seiten (Pages):
Aus der Charité: Barz MJ, Hof J, Groeneveld-Krentz S, Astrahantseff K, von Stackelberg A.Autoren:Correll CU et al.
Titel:Efficacy and Safety of Lumateperone for Treatment of Schizophrenia: A Randomized Clinical Trial.
Zeitschrift (Journal):Blood. 2020 Jan 22. doi: 10.1182/blood.2019002499. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Ratziu V et al.
Titel:Cenicriviroc Treatment for Adults with Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study.
Zeitschrift (Journal):Hepatology. 2020 Jan 13:10.1002/hep.31108. :Seiten (Pages):
Aus der Charité: Tacke F.Autoren:Schürmann D et al.
Titel:Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial.
Zeitschrift (Journal):Lancet HIV. 2020;S2352-3018(19)30372-8. :Seiten (Pages):
Aus der Charité: Schürmann D, Keicher C, Huser A, Hofmann J.Autoren:Bartels F et al.
Titel:Neuronal autoantibodies associated with cognitive impairment in melanoma patients.
Zeitschrift (Journal):Ann Oncol. 2019 May 1;30(5):823-829. :Seiten (Pages):
Aus der Charité: Bartels F, Stronisch T, Farmer K, Kiecker F, Finke C.Autoren:Stintzing S et al.
Titel:Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial.
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Aus der Charité: Stintzing S.Autoren:Petutschnigg J et al.
Titel:Body fat phenotypes and treatment response to spironolactone in ambulatory patients with heart failure and preserved ejection fraction: a post-hoc analysis of the Aldo-DHF trial.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Jan 7:10.1002/ejhf.1723. :Seiten (Pages):
Aus der Charité: Petutschnigg J, Trippel TD, Hashemi D, Pieske B, Edelmann F.Autoren:Scheffel J et al.
Titel:Cold-induced urticarial autoinflammatory syndrome related to factor XII activation.
Zeitschrift (Journal):Nat Commun. 2020 Jan 10;11(1):179. :Seiten (Pages):
Aus der Charité: Scheffel J, Mahnke NA, Wu J, Bonnekoh H, Church MK, Maurer M, Krause K.
Publikationen 2019
Dezember 2019
Autoren:Stahn AC et al.
Titel:Brain Changes in Response to Long Antarctic Expeditions.
Zeitschrift (Journal):N Engl J Med. 2019 Dec 5;381(23):2273-2275. :Seiten (Pages):
Aus der Charité: Stahn AC, Gunga HC.Autoren:Deodhar A et al.
Titel:Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial.
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Aus der Charité: Poddubnyy D, Sieper J.Autoren:Koche RP et al.
Titel:Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Zeitschrift (Journal):Nat Genet. 2019 Dec 16;10.1038/s41588-019-0547-z. :Seiten (Pages):
Aus der Charité: Helmsauer K, MacArthur IC, Chamorro R, Munoz-Perez N, Dorado Garcia H, Bei Y, Röefzaad C, Bardinet V, Szymansky A, Winkler A, Thole T, Timme N, Fuchs S, Klironomos F, Schmelz K, Künkele A, Hundsdörfer P, Deubzer H, Toedling J, Hertwig F, Eggert A, Schulte JH, Henssen AG.Autoren:Solmi M et al.
Titel:Disparities in cancer screening in people with mental illness across the world versus the general population: prevalence and comparative meta-analysis including 4,717,839 people.
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Aus der Charité: Correll CU.Autoren:Stintzing S et al.
Titel:Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial.
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Aus der Charité: Stintzing S.Autoren:Möckel M et al.
Titel:Improve Management of acute heart failure with ProcAlCiTonin in EUrope: results of the randomized clinical trial IMPACT EU Biomarkers in Cardiology (BIC) 18.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Dec 12. doi: 10.1002/ejhf.1667. :Seiten (Pages):
Aus der Charité: Möckel M, Slagman AC.Autoren:Pieske B et al.
Titel:Baseline features of the VICTORIA (Vericiguat Global Study in Subjects with Heart Failure with Reduced Ejection Fraction) trial.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Dec;21(12):1596-1604. :Seiten (Pages):
Aus der Charité: Pieske B et al..Autoren:Marg A et al.
Titel:Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
Zeitschrift (Journal):Nat Commun. 2019 Dec 18;10(1):5776. :Seiten (Pages):
Aus der Charité: Marg A, Escobar H, Grunwald SA, Metzler E, Kieshauer J, Pasemann D, Schneider J, Schülke M, Spuler S.Autoren:Ziegler JF et al.
Titel:Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease.
Zeitschrift (Journal):Nat Commun. 2019 Dec 10;10(1):5629. :Seiten (Pages):
Aus der Charité: Ziegler JF, Böttcher C, Letizia M, Yerinde C, Wu H, Freise I, Rodriguez-Sillke Y, Stoyanova AK, Kreis ME, Asbach P, Kunkel D, Priller J, Anagnostopoulos I, Kühl AA, Bojarski C, Glauben R, Siegmund B, Weidinger C.Autoren:Gusic M et al.
Titel:Bi-Allelic UQCRFS1 Variants Are Associated with Mitochondrial Complex III Deficiency, Cardiomyopathy, and Alopecia Totalis.
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Aus der Charité: Schottmann G, Lee CY, Morales-Gonzalez S, Schuelke M.
November 2019
Autoren:Middleton PG et al.
Titel:Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.
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Titel:Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial.
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Titel:A support programme for secondary prevention in patients with transient ischaemic attack and minor stroke (INSPiRE-TMS): an open-label, randomised controlled trial.
Zeitschrift (Journal):Lancet Neurol. 2019 Nov 7. doi: 10.1016/S1474-4422(19)30369-2. :Seiten (Pages):
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Titel:Mapping microglia states in the human brain through the integration of high-dimensional techniques.
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Titel:Long-term effects of Na+ /Ca2+ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction.
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Titel:Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation.
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Titel:Niche-mimicking interactions in peptide-functionalized 3D hydrogels amplify mesenchymal stromal cell paracrine effects.
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Titel:Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington's disease.
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Titel:The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches.
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Oktober 2019
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Titel:Ligelizumab for Chronic Spontaneous Urticaria.
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Titel:Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses.
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Titel:Improving Stratification for Children With Late Bone Marrow B-Cell Acute Lymphoblastic Leukemia Relapses With Refined Response Classification and Integration of Genetics.
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Titel:Lipid droplet-dependent fatty acid metabolism controls the immune suppressive phenotype of tumor-associated macrophages.
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Titel:Reduction of Postoperative Wound Infections by Antiseptica (RECIPE)?: A Randomized Controlled Trial.
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Titel:Network-Specific Synchronization of Electrical Slow-Wave Oscillations Regulates Sleep Drive in Drosophila.
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Titel:CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer.
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Titel:Decision-Analytic Modeling for Time-Effectiveness of the Sequence of Induction Treatments for Moderate to Severe Plaque Psoriasis.
Zeitschrift (Journal):JAMA Dermatol. 2019 Oct 16. doi: 10.1001/jamadermatol.2019.2941. :Seiten (Pages):
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Titel:Association of uric acid levels before start of conditioning with mortality after alloSCT: a prospective, non-interventional study of the EBMT Transplant Complication Working Party.
Zeitschrift (Journal):Haematologica. 2019 Oct 10. doi: 10.3324/haematol.2019.228668. :Seiten (Pages):
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Titel:Clonal hematopoiesis in patients with ANCA-associated vasculitis.
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September 2019
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Titel:Physical Fitness Training in Patients with Subacute Stroke (PHYS-STROKE): multicentre, randomised controlled, endpoint blinded trial.
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Titel:How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).
Zeitschrift (Journal):Eur Heart J. 2019 Oct 21;40(40):3297-3317. :Seiten (Pages):
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Titel:Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.
Zeitschrift (Journal):Acta Neuropathol. 2019 Sep 28. doi: 10.1007/s00401-019-02078-w. :Seiten (Pages):
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Titel:Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases.
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Titel:Immunosuppression in inflammatory cardiomyopathy and parvovirus B19 persistence.
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Titel:R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
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Titel:Association of Cortical Glutamate and Working Memory Activation in Patients With Schizophrenia: A Multimodal Proton Magnetic Resonance Spectroscopy and Functional Magnetic Resonance Imaging Study. Biol Psychiatry. 2019 Jul 26. doi: 10.1016/j.biopsych.2019.07.011.
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Titel:Mast cells are critical for controlling the bacterial burden and the healing of infected wounds.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20500-20504. :Seiten (Pages):
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Titel:Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis.
Zeitschrift (Journal):Neurology. 2019 Oct 8;93(15):e1439-e1451. :Seiten (Pages):
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Titel:Tomoelastography distinguishes non-invasively between benign and malignant liver lesions.
Zeitschrift (Journal):Cancer Res. 2019 Sep 24. doi: 10.1158/0008-5472.CAN-19-2150. :Seiten (Pages):
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August 2019
Autoren:Olin-Sandoval V et al.
Titel:Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism.
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Titel:Risk of Psychosis Among Refugees: A Systematic Review and Meta-analysis.
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Titel:Association With Hospitalization and All-Cause Discontinuation Among Patients With Schizophrenia on Clozapine vs Other Oral Second-Generation Antipsychotics: A Systematic Review and Meta-analysis of Cohort Studies.
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Titel:Detection of KIT D816V mutation in patients with severe anaphylaxis and normal basal tryptase-first data from the Anaphylaxis Registry (NORA).
Zeitschrift (Journal):J Allergy Clin Immunol. 2019 Aug 12. doi: 10.1016/j.jaci.2019.07.037. :Seiten (Pages):
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Titel:Prevalence, 12-Month Prognosis, and Clinical Management Need of Depression in Coronary Heart Disease Patients: A Prospective Cohort Study.
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Titel:Deep brain stimulation induced normalization of the human functional connectome in Parkinson's disease.
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Titel:Connectivity profile of thalamic deep brain stimulation to effectively treat essential tremor.
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Titel:Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2019 Aug 23. doi: 10.1002/jcsm.12491. :Seiten (Pages):
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Titel:Highly diversified shrew hepatitis B viruses corroborate ancient origins and divergent infection patterns of mammalian hepadnaviruses.
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Juli 2019
Autoren:Despang A et al.
Titel:Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture.
Zeitschrift (Journal):Nat Genet. 2019 Aug;51(8):1263-1271. :Seiten (Pages):
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Titel:The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis.
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Titel:Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium.
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Titel:Enzymatically-degradable alginate hydrogels promote cell spreading and in vivo tissue infiltration.
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Titel:Haploinsufficiency of the Notch Ligand DLL1 Causes Variable Neurodevelopmental Disorders.
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Titel:High-resolution diffusion-weighted imaging identifies ischemic lesions in a majority of transient ischemic attack patients.
Zeitschrift (Journal):Ann Neurol. 2019 Jul 12. doi: 10.1002/ana.25551. :Seiten (Pages):
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Titel:Immunologic Profiling of Mutational and Transcriptional Subgroups in Pediatric and Adult High-Grade Gliomas.
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Titel:US Time-Harmonic Elastography for the Early Detection of Glomerulonephritis.
Zeitschrift (Journal):Radiology. 2019 Jul 9:182574. :Seiten (Pages):
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Titel:Kidney Injury after Intravenous versus Intra-arterial Contrast Agent in Patients Suspected of Having Coronary Artery Disease: A Randomized Trial.
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Titel:IgA autoantibodies against native myelin basic protein in a patient with MS.
Zeitschrift (Journal):Neurol Neuroimmunol Neuroinflamm. 2019 May 1;6(4):e569. :Seiten (Pages):
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Juni 2019
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Titel:Diagnosis of obstructive coronary artery disease using computed tomography angiography in patients with stable chest pain depending on clinical probability and in clinically important subgroups: meta-analysis of individual patient data.
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Titel:Dipeptidyl Peptidase-4 Inhibitors and the Risk of Bullous Pemphigoid Among Patients With Type 2 Diabetes.
Zeitschrift (Journal):Diabetes Care. 2019 Jun 10. doi: 10.2337/dc19-0409. :Seiten (Pages):
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Titel:Rationale and design of the EMPERIAL-Preserved and EMPERIAL-Reduced trials of empagliflozin in patients with chronic heart failure.
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Titel:VEGF - Supplemented extracellular matrix is sufficient to induce endothelial differentiation of human iPSC.
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Titel:Outcome heterogeneity and bias in acute experimental spinal cord injury: A meta-analysis.
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Titel:PEDIA: prioritization of exome data by image analysis.
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Titel:Image-guided Irreversible Electroporation of Localized Prostate Cancer: Functional and Oncologic Outcomes.
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Mai 2019
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Titel:Effect of ultra-short-term treatment of patients with iron deficiency or anaemia undergoing cardiac surgery: a prospective randomised trial.
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Titel:Early discharge and home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban: an international multicenter single-arm clinical trial.
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Titel:Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis.
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Titel:Collagen Fibrils Mechanically Contribute to Tissue Contraction in an In Vitro Wound Healing Scenario.
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Titel:Killer-like receptors and GPR56 progressive expression defines cytokine production of human CD4(+) memory T cells.
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Titel:Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis.
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Titel:RegulationSpotter: annotation and interpretation of extratranscriptic DNA variants.
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Titel:MutationDistiller: user-driven identification of pathogenic DNA variants.
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April 2019
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Titel:Acute and midterm outcomes of the post-approval MELODY Registry: a multicentre registry of transcatheter pulmonary valve implantation.
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Titel:Mutational Diversity and Therapy Response in Breast Cancer: A Sequencing Analysis in the Neoadjuvant GeparSepto Trial.
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Titel:Confirmation of the prognostic value of pretherapeutic tumor SUR and MTV in patients with esophageal squamous cell carcinoma.
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Titel:Damage of the lateral geniculate nucleus in MS: Assessing the missing node of the visual pathway.
Zeitschrift (Journal):Neurology. 2019 May 7;92(19):e2240-e2249 :Seiten (Pages):
Aus der Charité: Papadopoulou A, Brandt AU.
März 2019
Autoren:Spillmann F et al.
Titel:Mode-of-action of the PROPELLA concept in fulminant myocarditis.
Zeitschrift (Journal):Eur Heart J. 2019 Mar 19. doi: 10.1093/eurheartj/ehz124
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Titel:Neuronal Autoantibodies Associated with Cognitive Impairment in Melanoma Patients.
Zeitschrift (Journal):Ann Oncol. 2019 Mar 6. doi: 10.1093/annonc/mdz083
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Titel:Orphan disease status of cancer cachexia in the USA and in the European Union: a systematic re-view.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):22-34
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Titel:2018 EULAR recommendations for a core data set to support observational research and clinical care in giant cell arteritis.
Zeitschrift (Journal):Ann Rheum Dis. 2019 Mar 21. doi: 10.1136/annrheumdis-2018-214755
Autoren:Dörner T et al.
Titel:Treatment of primary Sjögren's syndrome with ianalumab (VAY736) targeting B cells by BAFF re-ceptor blockade coupled with enhanced, antibody-dependent cellular cytotoxicity.
Zeitschrift (Journal):Ann Rheum Dis. 2019 Mar 2. doi: 10.1136/annrheumdis-2018-214720
Autoren:Bobenko A et al.
Titel:Exercise training in patients with a left ventricular assist device (Ex-VAD): rationale and design of a multicentre, prospective, assessor-blinded, randomized, controlled trial.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Mar 28. doi: 10.1002/ejhf.1431
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Titel:N-Methyl-D-Aspartate Receptor Dysfunction by Unmutated Human Antibodies Against the NR1 Subunit.
Zeitschrift (Journal):Ann Neurol. 2019 Mar 6. doi: 10.1002/ana.25460
Autoren:Bastian L et al.
Titel:PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.
Zeitschrift (Journal):Leukemia. 2019 Mar 6. doi: 10.1038/s41375-019-0430-z
Autoren:Stefanski AL, Wiedemann A, Reiter K, Hiepe F, Lino AC, Dörner T.
Titel:Enhanced PD-1 and diminished PD-L1 upregulation capacity mark post-activated lupus B cells.
Zeitschrift (Journal):Arthritis Rheumatol. 2019 Mar 27. doi: 10.1002/art.40897
Autoren:Schulz A et al.
Titel:Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage.
Zeitschrift (Journal):Elife. 2019 Mar 22;8
Februar 2019
Autoren:Gronke K et al.
Titel:Interleukin-22 protects intestinal stem cells against genotoxic stress.
Zeitschrift (Journal):Nature. 2019 Feb;566(7743):249-253
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Titel:Control of blood pressure and risk of mortality in a cohort of older adults: the Berlin Initiative Study.
Zeitschrift (Journal):Eur Heart J. 2019 Feb 25. doi: 10.1093/eurheartj/ehz071
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Titel:c-Maf-dependent T(reg) cell control of intestinal T(H)17 cells and IgA establishes host-microbiota homeostasis.
Zeitschrift (Journal):Nat Immunol. 2019 Feb 18. doi: 10.1038/s41590-019-0316-2
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Titel:Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations.
Zeitschrift (Journal):Nat Cell Biol. 2019 Mar;21(3):305-310
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Titel:Tick-Tock Hedgehog-Mutual crosstalk with liver circadian clock promotes liver steatosis.
Zeitschrift (Journal):J Hepatol. 2019 Jan 31. doi: 10.1016/j.jhep.2019.01.022
Autoren:Krupp F et al.
Titel:Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor.
Zeitschrift (Journal):Mol Cell. 2019 Feb 12. doi: 10.1016/j.molcel.2019.01.016
Autoren:Kulthanan K et al.
Titel:Treatments of Cold Urticaria: A Systematic Review.
Zeitschrift (Journal):J Allergy Clin Immunol. 2019 Feb 15. doi: 10.1016/j.jaci.2019.02.005
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Titel:ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans.
Zeitschrift (Journal):Nat Commun. 2019 Jan 30;10(1):486
Autoren:Lakin E, Church MK, Maurer M, Schmetzer O.
Titel:On the Lipophilic Nature of Autoreactive IgE in Chronic Spontaneous Urticaria.
Zeitschrift (Journal):Theranostics. 2019 Jan 25;9(3):829-836
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Titel:Widespread microglial activation in multiple system atrophy.
Zeitschrift (Journal):Mov Disord. 2019 Feb 6. doi: 10.1002/mds.27620
Januar 2019
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Titel:Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.
Zeitschrift (Journal):Blood. 2019 Jan 4. doi: 10.1182/blood-2018-05-852822
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Titel:Body weight changes and incidence of cachexia after stroke. J Cachexia Sarcopenia Muscle.
Zeitschrift (Journal):2019 Jan 24. doi: 10.1002/jcsm.12400
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Titel:Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Zeitschrift (Journal):Nat Commun. 2019 Jan 15;10(1):217
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Titel:Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats.
Zeitschrift (Journal):Mol Psychiatry. 2019 Jan 28. doi: 10.1038/s41380-019-0356-x
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Titel:Bio-Orthogonal Chemistry and Reloadable Biomaterial Enable Local Activation of Antibiotic Prodrugs and Enhance Treatments against Staphylococcus aureus Infections.
Zeitschrift (Journal):ACS Cent Sci. 2018 Dec 26;4(12):1624-1632
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Titel:Cardiac contractility modulation improves long-term survival and hospitalizations in heart failure with reduced ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Jan 16. doi: 10.1002/ejhf.1374
Autoren:Houtman J, Freitag K, Gimber N, Schmoranzer J, Heppner FL, Jendrach M.
Titel:Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3.
Zeitschrift (Journal):EMBO J. 2019 Feb 15;38(4)
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Titel:Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies.
Zeitschrift (Journal):Leukemia. 2019 Jan 3. doi: 10.1038/s41375-018-0330-7
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Titel:Use of a Repositionable and Fully Retrievable Aortic Valve in Routine Clinical Practice: The RESPOND Study and RESPOND Extension Cohort.
Zeitschrift (Journal):JACC Cardiovasc Interv. 2019 Jan 14;12(1):38-49
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Titel:Avelumab in patients with previously treated metastatic melanoma: phase 1b results from the JAVELIN Solid Tumor trial.
Zeitschrift (Journal):J Immunother Cancer. 2019 Jan 16;7(1):12