Ausgewählte Publikationen der Charité
Die Wissenschaftlerinnen und Wissenschaftler der Charité veröffentlichen mehr als 4.000 Fachpublikationen im Jahr.
Hier stellen wir Ihnen pro Monat zehn ausgewählte Publikationen vor.
Sie befinden sich hier:
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Publikationen 2022
Dezember 2022
Autoren:Anker SD et al.
Titel:Efficacy of empagliflozin in heart failure with preserved versus mid-range ejection fraction: a pre-specified analysis of EMPEROR-Preserved.
Zeitschrift (Journal):Nat Med. 2022 Dec;28(12):2512-2520. :Seiten (Pages):
Aus der Charité: Anker SD.
Autoren:Brevini T et al.
Titel:FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.
Zeitschrift (Journal):Nature. 2022 Dec 5. doi: 10.1038/s41586-022-05594-0. :Seiten (Pages):
Aus der Charité: Vallier L.
Autoren:Roediger J et al.
Titel:Automated deep brain stimulation programming based on electrode location: a randomised, crossover trial using a data-driven algorithm.
Zeitschrift (Journal):Lancet Digit Health. 2022 Dec 15:S2589-7500(22)00214-X. :Seiten (Pages):
Aus der Charité: Roediger J, Achtzehn J, Busch JL, Krämer AP, Faust K, Schneider GH, Krause P, Horn A, Kühn AA.Autoren:Felten M et al.
Titel:Ventilator-induced Lung Injury Is Modulated by the Circadian Clock.
Zeitschrift (Journal):Am J Respir Crit Care Med. 2022 Dec 8. doi: 10.1164/rccm.202202-0320OC. :Seiten (Pages):
Aus der Charité: Felten M, Ferencik S, Teixeira Alves LG, Lienau J, Müller-Redetzky HC, Michalick L, Kuebler WM, Ananthasubramaniam B, Maier B, Kramer A, Witzenrath M.Autoren:Erfinanda L et al.
Titel:Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation.
Zeitschrift (Journal):Sci Transl Med. 2022 Dec 7;14(674):eabg8577. :Seiten (Pages):
Aus der Charité: Erfinanda L, Zou L, Gutbier B, Kneller L, Weidenfeld S, Michalick L, Lei D, Reppe K, Teixeira Alves LG, Schneider B, Zhang Q, Li C, Fatykhova D, Hocke A, Hippenstiel S, Suttorp N, Mall MA, Witzenrath M, Kuebler WM.Autoren:Harnett D et al.
Titel:A critical period of translational control during brain development at codon resolution.
Zeitschrift (Journal):Nat Struct Mol Biol. 2022 Dec;29(12):1277-1290. :Seiten (Pages):
Aus der Charité: Ambrozkiewicz MC, Dannenberg R, Münster-Wandowski A, Spahn CMT, Tarabykin V.
Autoren:Bonczarowska JH et al.
Titel:Pathogen genomics study of an early medieval community in Germany reveals extensive co-infections.
Zeitschrift (Journal):Genome Biol. 2022 Dec 13;23(1):250. :Seiten (Pages):
Aus der Charité: Mühlemann B, Jones TC.Autoren:Sauer K et al.
Titel:Primary radiation damage in bone evolves via collagen destruction by photoelectrons and secondary emission self-absorption.
Zeitschrift (Journal):Nat Commun. 2022 Dec 20;13(1):7829. :Seiten (Pages):
Aus der Charité: Sauer K, Zaslansky P.Autoren:Ríos AS et al.
Titel:Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer's disease.
Zeitschrift (Journal):Nat Commun. 2022 Dec 14;13(1):7707. :Seiten (Pages):
Aus der Charité: Ríos AS, Oxenford S, Neudorfer C, Butenko K, Li N, Rajamani N, Horn A.Autoren:Bader JM et al.
Titel:Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status.
Zeitschrift (Journal):Cell Rep Med. 2023 Jan 17;4(1):100877. :Seiten (Pages):
Aus der Charité: Misch M, Koch A.
November 2022
Autoren:Carrasco-Zanini J et al.
Titel:Proteomic signatures for identification of impaired glucose tolerance.
Zeitschrift (Journal):Nat Med. 2022 Nov;28(11):2293-2300. :Seiten (Pages):
Aus der Charité: Pietzner M, Langenberg C.
Autoren:Surendran P et al.
Titel:Rare and common genetic determinants of metabolic individuality and their effects on human health.
Zeitschrift (Journal):Nat Med. 2022 Nov;28(11):2321-2332. :Seiten (Pages):
Aus der Charité: Pietzner M, Langenberg C.Autoren:Jarick KJ et al.
Titel:Non-redundant functions of group 2 innate lymphoid cells.
Zeitschrift (Journal):Nature. 2022 Nov;611(7937):794-800. :Seiten (Pages):
Aus der Charité: Jarick KJ, Topczewska PM, Jakob MO, Gao X, Boulekou S, Stokic-Trtica V, Leclère PS, Preußer A, Rompe ZA, Stamm A, Ivanov A, Beule D, Helfrich S, Duerr CU, Kühl AA, Stehle C, Romagnani C, Diefenbach A, Klose CSN.
Autoren:Arends CM et al.
Titel:Associations of clonal haematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Zeitschrift (Journal):Blood. 2022 Nov 28. doi: 10.1182/blood.2022017661. :Seiten (Pages):
Aus der Charité: Arends CM, Strzelecka PM, Kufner A, Löwe P, Huo S, Stein CM, Piper SK, Tilgner M, Sperber PS, Dimitriou S, Hablesreiter R, Harms C, Bullinger L, Weber JE, Endres M, Damm F.Autoren:Gallo K et al.
Titel:SuperNatural 3.0-a database of natural products and natural product-based derivatives.
Zeitschrift (Journal):Nucleic Acids Res. 2022 Nov 18. doi: 10.1093/nar/gkac1008. :Seiten (Pages):
Aus der Charité: Gallo K, Kemmler E, Goede A, Becker F, Dunkel M, Preissner R, Banerjee P.Autoren:Anker SD et al.
Titel:Weight change and clinical outcomes in heart failure with reduced ejection fraction: insights from EMPEROR-Reduced.
Zeitschrift (Journal):Eur J Heart Fail. 2022 Nov 2. doi: 10.1002/ejhf.2728. :Seiten (Pages):
Aus der Charité: Anker SD, Doehner W.Autoren:Jurmeister P et al.
Titel:DNA methylation-based classification of sinonasal tumors.
Zeitschrift (Journal):Nat Commun. 2022 Nov 28;13(1):7148 :Seiten (Pages):
Aus der Charité: Jurmeister P, Glöß S, Roller R, Leitheiser M, Schmid S, Fritz R, Dittmayer C, Friedrich C, Thieme A, Keyl P, Jarosch A, Schallenberg S, Hoffmann I, Vollbrecht C, Lehmann A, Hummel M, Heim D, Bockmayr M, Koch A, Heppner F, Capper D.Autoren:Fernández Zapata C et al.
Titel:Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer's disease.
Zeitschrift (Journal):Nat Commun. 2022 Nov 23;13(1):7210. :Seiten (Pages):
Aus der Charité: Fernández Zapata C, Spruth EJ, Gallaccio G, Dehlinger A, Dames C, Leman JKH, Meisel A, Schlickeiser S, Kunkel D, Paul F, Priller J, Böttcher C.Autoren:Vierock J et al.
Titel:WiChR, a highly potassium-selective channelrhodopsin for low-light one- and two-photon inhibition of excitable cells.
Zeitschrift (Journal):Sci Adv. 2022 Dec 9;8(49):eadd7729. :Seiten (Pages):
Aus der Charité: Vierock J, Tillert L.Autoren:Terhorst-Molawi D et al.
Titel:Anti-KIT antibody, barzolvolimab, reduces skin mast cells and disease activity in chronic inducible urticaria.
Zeitschrift (Journal):Allergy. 2022 Nov 16. doi: 10.1111/all.15585. :Seiten (Pages):
Aus der Charité: Terhorst-Molawi D, Grekowitz E, Kiefer L, Metz M, Maurer M.
Oktober 2022
Autoren:Ringel AR et al.
Titel:Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes.
Zeitschrift (Journal):Cell. 2022 Sep 29;185(20):3689-3704.e21. :Seiten (Pages):
Aus der Charité: Ringel AR, Schöpflin R, Phan MHQ, Ibrahim DM, Mundlos S, Robson MI.Autoren:Ercu M et al.
Titel:Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage.
Zeitschrift (Journal):Circulation. 2022 Oct 19. doi: 10.1161/CIRCULATIONAHA.122.060210. :Seiten (Pages):
Aus der Charité: Mücke MB, Markó L, Sholokh A, Esmati Y, Gong M, Batolomaeus TUP, Forslund SK, Müller DN, Bähring S, Hübner N, Bader M.Autoren:Rückert T et al.
Titel:Clonal expansion and epigenetic inheritance of long-lasting NK cell memory.
Zeitschrift (Journal):Nat Immunol. 2022 Nov;23(11):1551-1563. :Seiten (Pages):
Aus der Charité: Ludwig LS, Romagnani C.Autoren:Schöpflin R et al.
Titel:Integration of Hi-C with short and long-read genome sequencing reveals the structure of germline rearranged genomes.
Zeitschrift (Journal):Nat Commun. 2022 Oct 29;13(1):6470. :Seiten (Pages):
Aus der Charité: Schöpflin R, Melo US, Hertzberg J, Holtgrewe M, Klever MK, Jungnitsch J, Türkmen S, Horn D, Mundlos S.Autoren:Immisch L et al.
Titel:H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma.
Zeitschrift (Journal):J Immunother Cancer. 2022 Oct;10(10):e005535. :Seiten (Pages):
Aus der Charité: Immisch L, Papafotiou G, Willimsky G.Autoren:Schweizer U et al.
Titel:Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice.
Zeitschrift (Journal):Redox Biol. 2022 Sep 24;57:102490. :Seiten (Pages):
Aus der Charité: Wirth EK, Köhrle J, Schomburg L.Autoren:Haber AC et al.
Titel:Open tools for quantitative anonymization of tabular phenotype data: literature review.
Zeitschrift (Journal):Brief Bioinform. 2022 Oct 10:bbac440. :Seiten (Pages):
Aus der Charité: Haber AC, Prasser F.Autoren:Rohmann JL et al.
Titel:Effect of mobile stroke unit dispatch in all patients with acute stroke or TIA.
Zeitschrift (Journal):Ann Neurol. 2022 Oct 30. doi: 10.1002/ana.26541. Epub ahead of print. :Seiten (Pages):
Aus der Charité: Rohmann JL, Piccininni M, Ebinger M, Weber JE, Geisler F, Freitag E, Harmel P, Lorenz-Meyer I, Rohrpasser-Napierkowski I, Nolte CH, Endres M, Audebert HJ.Autoren:Kleefeld F et al.
Titel:Morphologic and Molecular Patterns of Polymyositis With Mitochondrial Pathology and Inclusion Body Myositis.
Zeitschrift (Journal):Neurology. 2022 Nov 15;99(20):e2212-e2222. :Seiten (Pages):
Aus der Charité: Kleefeld F, Schneider U, Goebel HH, Schuelke M, Hahn K, Preusse C, Stenzel W.Autoren:Correll CU et al.
Titel:Reduction in Multiple Cardiometabolic Risk Factors With Combined Olanzapine/Samidorphan Compared With Olanzapine: Post Hoc Analyses From a 24-Week Phase 3 Study.
Zeitschrift (Journal):Schizophr Bull. 2022 Oct 28:sbac144. :Seiten (Pages):
Aus der Charité: Correll CU.
September 2022
Autoren:Buergel T et al.
Titel:Metabolomic profiles predict individual multidisease outcomes.
Zeitschrift (Journal):Nat Med. 2022 Sep 22. doi: 10.1038/s41591-022-01980-3. :Seiten (Pages):
Aus der Charité: -Buergel T, Steinfeldt J, Ruyoga G, Pietzner M, Upmeier Zu Belzen J, Loock L, Kittner P, Christmann L, Hollmann N, Strangalies H, Braunger JM, Wild B, Spranger J, Klostermann F, Langenberg C, Eils R, Landmesser U.
Autoren:Ostendorf BN et al.
Titel:Common human genetic variants of APOE impact murine COVID-19 mortality.
Zeitschrift (Journal):Nature. 2022 Sep 21. doi: 10.1038/s41586-022-05344-2. :Seiten (Pages):
Aus der Charité: Ostendorf BN.Autoren:Lange JT et al.
Titel:The evolutionary dynamics of extrachromosomal DNA in human cancers.
Zeitschrift (Journal):Nat Genet. 2022 Oct;54(10):1527-1533. :Seiten (Pages):
Aus der Charité: Chen CY, Henssen AG.Autoren:Butler J et al.
Titel:Effects of Empagliflozin in Women and Men With Heart Failure and Preserved Ejection Fraction.
Zeitschrift (Journal):Circulation. 2022 Oct 4;146(14):1046-1055. :Seiten (Pages):
Aus der Charité: Rauch-Kröhnert U, Anker SD.Autoren:Haber PK et al.
Titel:Molecular Markers of Response to Anti-PD1 Therapy in Advanced Hepatocellular Carcinoma.
Zeitschrift (Journal):Gastroenterology. 2022 Sep 12:S0016-5085(22)01039-3. :Seiten (Pages):
Aus der Charité: Haber PK, Özdirik B, Müller T, Schmelzle M, Llovet JM.Autoren:Knorr J et al.
Titel:Interleukin-18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis.
Zeitschrift (Journal):Hepatology. 2022 Sep 4. doi: 10.1002/hep.32776. :Seiten (Pages):
Aus der Charité: Knorr J, Holtmann TM, Geisler L, Hundertmark J, Kohlhepp MS, Demir M, Tacke F, Wree A.Autoren:Böhm M et al.
Titel:Heart failure outcomes according to heart rate and effects of empagliflozin in patients of the EMPEROR-Preserved trial.
Zeitschrift (Journal):Eur J Heart Fail. 2022 Sep 10. doi: 10.1002/ejhf.2677. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Sibille J et al.
Titel:High-density electrode recordings reveal strong and specific connections between retinal ganglion cells and midbrain neurons.
Zeitschrift (Journal):Nat Commun. 2022 Sep 5;13(1):5218. :Seiten (Pages):
Aus der Charité: Sibille J, Gehr C, Balasubramanian H, Teh KL, Lupashina T, Kremkow J.Autoren:Ebert MJ et al.
Titel:Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.
Zeitschrift (Journal):J Clin Invest. 2022 Sep 20:e160089. :Seiten (Pages):
Aus der Charité: Ebert MJ, Jerke U, Eulenberg-Gustavus C, Kling L, Kirchner M, Mertins P, Eckardt KU, Schreiber A, Kettritz R.Autoren:Fischer AS et al.
Titel:R-spondin-YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.
Zeitschrift (Journal):J Clin Invest. 2022 Sep 13:e151363. :Seiten (Pages):
Aus der Charité: Fischer AS, Müllerke S, Arnold A, Heuberger J, Berger H, Lin M, Wizenty J, Horst D, Tacke F, Sigal M.
August 2022
Autoren:Broto M et al.
Titel:Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs.
Zeitschrift (Journal):Nat Nanotechnol. 2022 Aug 4. doi: 10.1038/s41565-022-01179-0. :Seiten (Pages):
Aus der Charité: Kaminski MM, Greensmith R, Schubert AJ.Autoren:Zhai Y et al.
Titel:Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.
Zeitschrift (Journal):Mol Cancer. 2022 Aug 19;21(1):166. doi: 10.1186/s12943-022-01635-4. :Seiten (Pages):
Aus der Charité: Dolnik A, Bullinger L.Autoren:Proft F et al.
Titel:Early identification of axial psoriatic arthritis among patients with psoriasis: a prospective multicentre study.
Zeitschrift (Journal):Ann Rheum Dis. 2022 Aug 3:annrheumdis-2022-222562. :Seiten (Pages):
Aus der Charité: Proft F, Lüders S, Rios Rodriguez V, Protopopov M, Poddubnyy D.Autoren:Solmi M et al.
Titel:Efficacy and acceptability of psychosocial interventions in schizophrenia: systematic overview and quality appraisal of the meta-analytic evidence.
Zeitschrift (Journal):Mol Psychiatry. 2022 Aug 23. doi: 10.1038/s41380-022-01727-z. :Seiten (Pages):
Aus der Charité: Solmi M, Correll CU.Autoren:Pietzner M et al.
Titel:ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19.
Zeitschrift (Journal):Nat Commun. 2022 Aug 15;13(1):4484. :Seiten (Pages):
Aus der Charité: Pietzner M, Chua RL, Jechow K, Radbruch H, Trump S, Heidecker B, Heppner FL, Eils R, Mall MA, Sander LE, Lehmann I, Lukassen S, Conrad C, Langenberg C.Autoren:Wang Z et al.
Titel:Humoral immunity to SARS-CoV-2 elicited by combination COVID-19 vaccination regimens.
Zeitschrift (Journal):J Exp Med. 2022 Oct 3;219(10):e20220826. :Seiten (Pages):
Aus der Charité: Muenn F, Tober-Lau P, Hillus D, Kurth F, Sander LE, Gaebler C.Autoren:Letizia M et al.
Titel:Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Zeitschrift (Journal):EMBO Mol Med. 2022 Sep 7;14(9):e15687. :Seiten (Pages):
Aus der Charité: Letizia M, Gerbeth L, Sand A, Brunkhorst M, Weidner P, Ziegler JF, Böttcher C, Schlickeiser S, Fernández C, Kunkel D, Sanders A, Siegmund B, Weidinger C.Autoren:Kazmierski J et al.
Titel:Nonproductive exposure of PBMCs to SARS-CoV-2 induces cell-intrinsic innate immune responses.
Zeitschrift (Journal):Mol Syst Biol. 2022 Aug;18(8):e10961. :Seiten (Pages):
Aus der Charité: Kazmierski J, Friedmann K, Postmus D, Emanuel J, Jansen J, Richter A, Bosquillon de Jarcy L, Schüler C, Drosten C, Sander LE, Müller MA, Niemeyer D, Goffinet C.Autoren:Lebedin M.
Titel:Different classes of genomic inserts contribute to human antibody diversity.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2205470119. :Seiten (Pages):
Aus der Charité: Lebedin M, Vázquez García C, de la Rosa K.Autoren:Bressem KK et al.
Titel:Deep Learning Detects Changes Indicative of Axial Spondyloarthritis at MRI of Sacroiliac Joints.
Zeitschrift (Journal):Radiology. 2022 Aug 9:212526. :Seiten (Pages):
Aus der Charité: Bressem KK, Adams LC, Proft F, Hermann KGA, Diekhoff T, Spiller L, Niehues SM, Hamm B, Protopopov M, Rios Rodriguez V, Haibel H, Rademacher J, Torgutalp M, Vahldiek JL, Poddubnyy D.
Juli 2022
Autoren:Derks J et al.
Titel:Increasing the throughput of sensitive proteomics by plexDIA.
Zeitschrift (Journal):Nat Biotechnol. 2022 Jul 14. doi: 10.1038/s41587-022-01389-w. :Seiten (Pages):
Aus der Charité: Ralser M, Demichev V.Autoren:Noviello CM et al.
Titel:Structural mechanisms of GABAA receptor autoimmune encephalitis.
Zeitschrift (Journal):Cell. 2022 Jul 7;185(14):2469-2477.e13. :Seiten (Pages):
Aus der Charité: Kreye J, Prüss H.Autoren:Butler J et al.
Titel:Patiromer for the management of hyperkalemia in heart failure with reduced ejection fraction: the DIAMOND trial.
Zeitschrift (Journal):Eur Heart J. 2022 Jul 28:ehac401. doi: 10.1093/eurheartj/ehac401. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Doehner W et al.
Titel:Uric acid and sodium-glucose cotransporter-2 inhibition with empagliflozin in heart failure with reduced ejection fraction: the EMPEROR-reduced trial.
Zeitschrift (Journal):Eur Heart J. 2022 Jul 5:ehac320. :Seiten (Pages):
Aus der Charité: Doehner W, Anker SD.Autoren:Böhm M et al.
Titel:Empagliflozin Improves Outcomes in Patients With Heart Failure and Preserved Ejection Fraction Irrespective of Age.
Zeitschrift (Journal):J Am Coll Cardiol. 2022 Jul 5;80(1):1-18. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Mall MA et al.
Titel:Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3B, Randomized, Placebo-Controlled Study.
Zeitschrift (Journal):Am J Respir Crit Care Med. 2022 Jul 11. doi: 10.1164/rccm.202202-0392OC. :Seiten (Pages):
Aus der Charité: Mall MA.Autoren:Imoto Y et al.
Titel:Dynamin is primed at endocytic sites for ultrafast endocytosis.
Zeitschrift (Journal):Neuron. 2022 Jul 1:S0896-6273(22)00548-7. doi: 10.1016/j.neuron.2022.06.010. Epub ahead of print. :Seiten (Pages):
Aus der Charité: Fenske P, Mamer L, Zarebidaki F, Söhl-Kielczynski B, Trimbuch T, Rosenmund C.Autoren:Linde C et al.
Titel:Cardiac contractility modulation therapy improves health status in patients with heart failure with preserved ejection fraction: a pilot study (CCM-HFpEF).
Zeitschrift (Journal):Eur J Heart Fail. 2022 Jul 20. doi: 10.1002/ejhf.2619. :Seiten (Pages):
Aus der Charité: Tschöpe C.Autoren:Pocock SJ et al.
Titel:Biomarker-driven prognostic models in chronic heart failure with preserved ejection fraction: the EMPEROR-Preserved trial.
Zeitschrift (Journal):Eur J Heart Fail. 2022 Jul 7. doi: 10.1002/ejhf.2607. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Dorado García H et al.
Titel:Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Zeitschrift (Journal):Nat Commun. 2022 Jul 25;13(1):4297. :Seiten (Pages):
Aus der Charité: Dorado García H, Pusch F, Bei Y, von Stebut J, Helmsauer K, Meyer-Liesener S, Timme N, Bardinet V, Chamorro González R, MacArthur IC, Chen CY, Schulz J, Furth C, Lala B, Eggert A, Seifert G, Hundsoerfer P, Lissat A, Dubois F, Horst D, Schulte JH, Spuler S, Haase K, Scheer M, Henssen AG.Autoren:Demichev V et al.
Titel:dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts.
Zeitschrift (Journal):Nat Commun. 2022 Jul 8;13(1):3944. :Seiten (Pages):
Aus der Charité: Demichev V, Szyrwiel L, Niewienda A, Ludwig D, Mülleder M, Ralser M.
Juni 2022
Autoren:Hilal T et al.
Titel:Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Zeitschrift (Journal):Science. 2022 Jun 17;376(6599):1338-1343. :Seiten (Pages):
Aus der Charité: Hilal T, Loerke J, Bürger J, Spahn CMT.Autoren:Filippatos G et al.
Titel:Empagliflozin for Heart Failure With Preserved Left Ventricular Ejection Fraction With and Without Diabetes.
Zeitschrift (Journal):Circulation. 2022 Jun 28. doi: 10.1161/CIRCULATIONAHA.122.059785. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Berlak M et al.
Titel:Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Zeitschrift (Journal):Mol Cancer. 2022 Jun 10;21(1):126. :Seiten (Pages):
Aus der Charité: Berlak M, Dorel M, Winkler A, McGearey A, Rodriguez-Fos E, Dorado-Garcia H, Lang P, Deubzer HE, Künkele A, Eggert A, Henssen AG, Hertwig F, Blüthgen N, Schulte JH.Autoren:Ostuzzi G et al.
Titel:Continuing, reducing, switching, or stopping antipsychotics in individuals with schizophrenia-spectrum disorders who are clinically stable: a systematic review and network meta-analysis.
Zeitschrift (Journal):Lancet Psychiatry. 2022 Aug;9(8):614-624. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Torgutalp M et al.
Titel:Treatment with tumour necrosis factor inhibitors is associated with a time-shifted retardation of radiographic spinal progression in patients with axial spondyloarthritis.
Zeitschrift (Journal):Ann Rheum Dis. 2022 Jun 13. doi: 10.1136/annrheumdis-2022-222324. :Seiten (Pages):
Aus der Charité: Torgutalp M, Rios Rodriguez V, Proft F, Protopopov M, Verba M, Rademacher J, Haibel H, Sieper J, Poddubnyy D.Autoren:Wiebe E et al.
Titel:Optimising both disease control and glucocorticoid dosing is essential for bone protection in patients with rheumatic disease.
Zeitschrift (Journal):Ann Rheum Dis. 2022 Jun 9. doi: 10.1136/annrheumdis-2022-222339. :Seiten (Pages):
Aus der Charité: Wiebe E, Huscher D, Schaumburg D, Palmowski A, Hermann S, Buttgereit T, Biesen R, Burmester GR, Palmowski Y, Buttgereit F.Autoren:Steinhaus R et al.
Titel:FABIAN-variant: predicting the effects of DNA variants on transcription factor binding.
Zeitschrift (Journal):Nucleic Acids Res. 2022 May 26;50(W1):W322–9. :Seiten (Pages):
Aus der Charité: Steinhaus R, Seelow D.Autoren:Hönzke K et al.
Titel:Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Zeitschrift (Journal):Eur Respir J. 2022 Jun 21:2102725. :Seiten (Pages):
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Titel:Cross-sectional seroprevalence surveys of SARS-CoV-2 antibodies in children in Germany, June 2020 to May 2021.
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Titel:A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth.
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Mai 2022
Autoren:Correll CU et al.
Titel:Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors.
Zeitschrift (Journal):World Psychiatry. 2022 Jun;21(2):248-271. :Seiten (Pages):
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Titel:Oral and long-acting antipsychotics for relapse prevention in schizophrenia-spectrum disorders: a network meta-analysis of 92 randomized trials including 22,645 participants.
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Titel:Effect of Denosumab Added to 2 Different nab-Paclitaxel Regimens as Neoadjuvant Therapy in Patients With Primary Breast Cancer: The GeparX 2 × 2 Randomized Clinical Trial.
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Titel:Brain simulation augments machine-learning-based classification of dementia.
Zeitschrift (Journal):Alzheimers Dement (N Y). 2022 May 15;8(1):e12303. :Seiten (Pages):
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Titel:Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Lung Clearance Index and Magnetic Resonance Imaging in Patients with Cystic Fibrosis and One or Two F508del Alleles.
Zeitschrift (Journal):Am J Respir Crit Care Med. 2022 May 10. doi: 10.1164/rccm.202201-0219OC. :Seiten (Pages):
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Titel:Mechanism of action of baricitinib and identification of biomarkers and key immune pathways in patients with active systemic lupus erythematosus.
Zeitschrift (Journal):Ann Rheum Dis. 2022 May 24:annrheumdis-2022-222335. :Seiten (Pages):
Aus der Charité: Dörner T.Autoren:Preuße C et al.
Titel:Skeletal muscle provides the immunological micro-milieu for specific plasma cells in anti-synthetase syndrome-associated myositis.
Zeitschrift (Journal):Acta Neuropathol. 2022 May 25. doi: 10.1007/s00401-022-02438-z. :Seiten (Pages):
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Titel:Mycobacterium tuberculosis-specific CD4 T-cell scoring discriminates tuberculosis infection from disease.
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Titel:Outcomes with empagliflozin in heart failure with preserved ejection fraction using DELIVER-like endpoint definitions.
Zeitschrift (Journal):Eur J Heart Fail. 2022 May 23. doi: 10.1002/ejhf.2558. :Seiten (Pages):
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Titel:ADAMTS4-specific MR probe to assess aortic aneurysms in vivo using synthetic peptide libraries.
Zeitschrift (Journal):Nat Commun. 2022 May 23;13(1):2867. :Seiten (Pages):
Aus der Charité: Kaufmann JO, Brangsch J, Kader A, Mangarova DB, Adams LC, Möckel J, Taupitz M, Hamm B, Makowski MR.Autoren:Radke J et al.
Titel:The genomic and transcriptional landscape of primary central nervous system lymphoma.
Zeitschrift (Journal):Nat Commun. 2022 May 10;13(1):2558. :Seiten (Pages):
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April 2022
Autoren:Trubetskoy V et al.
Titel:Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Zeitschrift (Journal):Nature. 2022 Apr;604(7906):502-508. :Seiten (Pages):
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Titel:Efficacy of Augmentation of Cognitive Behavioral Therapy With Transcranial Direct Current Stimulation for Depression: A Randomized Clinical Trial.
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Titel:Safety of ixekizumab in patients with psoriatic arthritis: data from four clinical trials with over 2000 patient-years of exposure.
Zeitschrift (Journal):Ann Rheum Dis. 2022 Apr 7:annrheumdis-2021-222027. :Seiten (Pages):
Aus der Charité: Burmester GR.Autoren:Jiang T et al.
Titel:Stimulation of the EP3 receptor causes lung edema by activation of TRPC6 in pulmonary endothelial cells.
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Titel:Psychosocial functioning in the balance between autism and psychosis: evidence from three populations.
Zeitschrift (Journal):Mol Psychiatry. 2022 Apr 14. doi: 10.1038/s41380-022-01543-5. :Seiten (Pages):
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Titel:Effects of caloric restriction on the gut microbiome are linked with immune senescence.
Zeitschrift (Journal):Microbiome. 2022 Apr 4;10(1):57. :Seiten (Pages):
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Titel:Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study.
Zeitschrift (Journal):Brain. 2022 Apr 12:awab457. :Seiten (Pages):
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Titel:Molecular reactivity profiling upon immunotherapy with a 300 IR sublingual house dust mite tablet reveals marked humoral changes towards major allergens.
Zeitschrift (Journal):Allergy. 2022 Apr 26. doi: 10.1111/all.15327. :Seiten (Pages):
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Titel:Idiopathic mast cell activation syndrome is more often suspected than diagnosed-A prospective real-life study.
Zeitschrift (Journal):Allergy. 2022 Apr 1. doi: 10.1111/all.15304. :Seiten (Pages):
Aus der Charité: Buttgereit T, Gu S, Gutsche A, Maurer M, Siebenhaar F.Autoren:Lemoine M et al.
Titel:Screening HIV patients at risk for NAFLD using MRI-PDFF and transient elastography: a European multicenter prospective study.
Zeitschrift (Journal):Clin Gastroenterol Hepatol. 2022 Apr 15:S1542-3565(22)00390-1. :Seiten (Pages):
Aus der Charité: Post G, Ingiliz P.
März 2022
Autoren:DISCHARGE Trial Group et al.
Titel:CT or Invasive Coronary Angiography in Stable Chest Pain.
Zeitschrift (Journal):N Engl J Med. 2022 Mar 4. doi: 10.1056/NEJMoa2200963. :Seiten (Pages):
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Titel:Mineralocorticoid Receptor Antagonists and Empagliflozin in Patients With Heart Failure and Preserved Ejection Fraction.
Zeitschrift (Journal):J Am Coll Cardiol. 2022 Mar 29;79(12):1129-1137. :Seiten (Pages):
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Titel:Pausing methotrexate improves immunogenicity of COVID-19 vaccination in elderly patients with rheumatic diseases.
Zeitschrift (Journal):Ann Rheum Dis. 2022 Mar 14:annrheumdis-2021-221876. :Seiten (Pages):
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Titel:Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance.
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Titel:Responder analysis for improvement in six-minute walk test with ferric carboxymaltose in patients with heart failure with reduced ejection fraction and iron deficiency.
Zeitschrift (Journal):Eur J Heart Fail. 2022 Mar 25. doi: 10.1002/ejhf.2491. :Seiten (Pages):
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Titel:Finerenone in patients with CKD and T2D with and without heart failure: A prespecified subgroup analysis of the FIDELIO-DKD trial.
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Titel:BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
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Titel:Biodegradable magnesium fixation screw for barrier membranes used in guided bone regeneration.
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Titel:Biodegradable magnesium barrier membrane used for guided bone regeneration in dental surgery.
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Titel:TADA-a machine learning tool for functional annotation-based prioritisation of pathogenic CNVs.
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Februar 2022
Autoren:Brandt L et al.
Titel:Adverse events after antipsychotic discontinuation: an individual participant data meta-analysis.
Zeitschrift (Journal):Lancet Psychiatry. 2022 Mar;9(3):232-242. :Seiten (Pages):
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Titel:Comparison of Mobile Stroke Unit With Usual Care for Acute Ischemic Stroke Management: A Systematic Review and Meta-analysis.
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Titel:Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
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Titel:Iron deficiency is related to low functional outcome in patients at early rehabilitation after acute stroke.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2022 Feb 14. doi: 10.1002/jcsm.12927. :Seiten (Pages):
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Titel:Humoral immune response to COVID-19 mRNA vaccination in relation to selenium status.
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Titel:NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
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Titel:Personalizing deep brain stimulation using advanced imaging sequences.
Zeitschrift (Journal):Ann Neurol. 2022 Feb 14. doi: 10.1002/ana.26326. :Seiten (Pages):
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Titel:Effect of Sunitinib Treatment on Skin Sodium Accumulation in Patients With Renal Cancer: a Pilot Study.
Zeitschrift (Journal):Hypertension. 2022 Feb 22:HYPERTENSIONAHA12219079. :Seiten (Pages):
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Titel:The role of cell-free hemoglobin and haptoglobin in acute kidney injury in critically ill adults with ARDS and therapy with VV ECMO.
Zeitschrift (Journal):Crit Care. 2022 Feb 22;26(1):50. :Seiten (Pages):
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Titel:A framework to score the effects of structural variants in health and disease.
Zeitschrift (Journal):Genome Res. 2022 Feb 23:gr.275995.121. :Seiten (Pages):
Aus der Charité: Kleinert P, Kircher M.
Januar 2022
Autoren:Gruell H et al.
Titel:mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant.
Zeitschrift (Journal):Nat Med. 2022 Jan 19:1–4. :Seiten (Pages):
Aus der Charité: Tober-Lau P, Hillus D, Kurth F, Sander LE.Autoren:Reincke SM et al.
Titel:SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Zeitschrift (Journal):Science. 2022 Jan 25:eabm5835. :Seiten (Pages):
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Titel:Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Zeitschrift (Journal):Cell. 2021 Dec 28:S0092-8674(21)01562-2. :Seiten (Pages):
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Titel:Neural network-based integration of polygenic and clinical information: development and validation of a prediction model for 10-year risk of major adverse cardiac events in the UK Biobank cohort.
Zeitschrift (Journal):Lancet Digit Health. 2022 Feb;4(2):e84-e94. :Seiten (Pages):
Aus der Charité: Steinfeldt J, Buergel T, Loock L, Kittner P, Ruyoga G, Zu Belzen JU, Sasse S, Strangalies H, Christmann L, Hollmann N, Wolf B, Landmesser U, Eils R.Autoren:Schick M et al.
Titel:Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.
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Titel:Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment.
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Aus der Charité: Jahn D, Appelt J, Albrecht KK, Otto E, Köhli P, Fuchs M, Tsitsilonis S, Keller J.Autoren:Ganos C et al.
Titel:A neural network for tics: insights from causal brain lesions and deep brain stimulation.
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Titel:Impact of protocol-based physiotherapy on insulin sensitivity and peripheral glucose metabolism in critically ill patients.
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Titel:Intramuscular and intratendinous placenta-derived mesenchymal stromal-like cell treatment of a chronic quadriceps tendon rupture.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2022 Jan 5. doi: 10.1002/jcsm.12894. :Seiten (Pages):
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Titel:Claudin-10a Deficiency Shifts Proximal Tubular Cl- Permeability to Cation Selectivity via Claudin-2 Redistribution.
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Publikationen 2021
Dezember 2021
Autoren:Forslund SK et al.
Titel:Combinatorial, additive and dose-dependent drug-microbiome associations.
Zeitschrift (Journal):Nature. 2021 Dec;600(7889):500-505. :Seiten (Pages):
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Titel:SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.
Zeitschrift (Journal):Cell. 2021 Dec 22;184(26):6243-6261.e27. :Seiten (Pages):
Aus der Charité: Wendisch D, Mittermaier M, Chua RL, Timm S, Brumhard S, Hiller AL, Pascual-Reguant A, Mothes R, Pott F, Kazmierski J, Radke J, Pergantis P, Conrad C, Sawitzki B, Horst D, Hippenstiel S, Hocke A, Heppner FL, Uhrig A, Garcia C, Machleidt F, Elezkurtaj S, Thibeault C, Witzenrath M, Suttorp N, Drosten C, Goffinet C, Kurth F, Radbruch H, Ochs M, Eils R, Müller-Redetzky H, Hauser AE, Conrad C, Selbach M, Sander LE.Autoren:Fleseriu M et al.
Titel:Maintenance of response to oral octreotide compared with injectable somatostatin receptor ligands in patients with acromegaly: a phase 3, multicentre, randomised controlled trial.
Zeitschrift (Journal):Lancet Diabetes Endocrinol. 2021 Dec 22:S2213-8587(21)00296-5. :Seiten (Pages):
Aus der Charité: Strasburger CJ.Autoren:Sutharsan S et al.
Titel:Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial.
Zeitschrift (Journal):Lancet Respir Med. 2021 Dec 20:S2213-2600(21)00454-9. :Seiten (Pages):
Aus der Charité: Mall MA.Autoren:Butler J et al.
Titel:Effect of empagliflozin in patients with heart failure across the spectrum of left ventricular ejection fraction.
Zeitschrift (Journal):Eur Heart J. 2021 Dec 8:ehab798. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Demir M et al.
Titel:The fecal mycobiome in non-alcoholic fatty liver disease.
Zeitschrift (Journal):J Hepatol. 2021 Dec 10:S0168-8278(21)02238-8. :Seiten (Pages):
Aus der Charité: Demir M, Roderburg C, Tacke F.Autoren:Arends CM et al.
Titel:Clonal hematopoiesis associates with improved survival in metastatic colorectal cancer patients from the FIRE-3 trial.
Zeitschrift (Journal):Blood. 2021 Dec 21:blood.2021014108. :Seiten (Pages):
Aus der Charité: Arends CM, Stahler A, Hablesreiter R, Strzelecka PM, Stein CM, Tilgner M, Bullinger L, Modest DP, Stintzing S, Damm F.Autoren:Graeber SY et al.
Titel:Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on CFTR Function in Patients with Cystic Fibrosis and One or Two F508del Alleles.
Zeitschrift (Journal):Am J Respir Crit Care Med. 2021 Dec 22. doi: 10.1164/rccm.202110-2249OC. :Seiten (Pages):
Aus der Charité: Graeber SY, Vitzthum C, Stahl M, Rohrbach A, Drescher M, Mall MA.Autoren:Radke MH et al.
Titel:Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue.
Zeitschrift (Journal):Sci Transl Med. 2021 Dec;13(622):eabe8952. :Seiten (Pages):
Aus der Charité: Parakkat P, Carballo JL, Gotthardt M.Autoren:Altrichter S et al.
Titel:An open-label, proof-of-concept study of lirentelimab for antihistamine-resistant chronic spontaneous and inducible urticaria.
Zeitschrift (Journal):J Allergy Clin Immunol. 2021 Dec 23:S0091-6749(21)02682-8. :Seiten (Pages):
Aus der Charité: Altrichter S, Siebenhaar F, Maurer M.
November 2021
Autoren:Pieske B et al.
Titel:Effect of Sacubitril/Valsartan vs Standard Medical Therapies on Plasma NT-proBNP Concentration and Submaximal Exercise Capacity in Patients With Heart Failure and Preserved Ejection Fraction: The PARALLAX Randomized Clinical Trial.
Zeitschrift (Journal):JAMA. 2021 Nov 16;326(19):1919-1929. :Seiten (Pages):
Aus der Charité: Pieske B.Autoren:Lam BYH et al.
Titel:MC3R links nutritional state to childhood growth and the timing of puberty.
Zeitschrift (Journal):Nature. 2021 Nov;599(7885):436-441. :Seiten (Pages):
Aus der Charité: Langenberg C.Autoren:Metz M et al.
Titel:Fenebrutinib in H1 antihistamine-refractory chronic spontaneous urticaria: a randomized phase 2 trial.
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Aus der Charité: Metz M, Maurer M.Autoren:Fischer M et al.
Titel:Ceritinib in paediatric patients with anaplastic lymphoma kinase-positive malignancies: an open-label, multicentre, phase 1, dose-escalation and dose-expansion study.
Zeitschrift (Journal):Lancet Oncol. 2021 Dec;22(12):1764-1776. :Seiten (Pages):
Aus der Charité: Schulte JH.Autoren:Butler J et al.
Titel:Empagliflozin, Health Status, and Quality of Life in Patients with Heart Failure and Preserved Ejection Fraction: The EMPEROR-Preserved Trial.
Zeitschrift (Journal):Circulation. 2021 Nov 15. doi: 10.1161/CIRCULATIONAHA.121.057812. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Berndt N et al.
Titel:CARDIOKIN1: Computational Assessment of Myocardial Metabolic Capability in Healthy Controls and Patients With Valve Diseases.
Zeitschrift (Journal):Circulation. 2021 Nov 11. doi: 10.1161/CIRCULATIONAHA.121.055646. :Seiten (Pages):
Aus der Charité: Berndt N, Eckstein J, Wallach I, Nordmeyer S, Kelm M, Goubergrits L, Schafstedde M, Hennemuth A, Kuehne T, Holzhütter HG.Autoren:Triana S et al.
Titel:Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states.
Zeitschrift (Journal):Nat Immunol. 2021 Dec;22(12):1577-1589. :Seiten (Pages):
Aus der Charité: Jopp-Saile L, Haas S.Autoren:Pietzner M et al.
Titel:Synergistic insights into human health from aptamer- and antibody-based proteomic profiling.
Zeitschrift (Journal):Nat Commun. 2021 Nov 24;12(1):6822. :Seiten (Pages):
Aus der Charité: Pietzner M, Langenberg C.Autoren:Schmelz K et al.
Titel:Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Zeitschrift (Journal):Nat Commun. 2021 Nov 23;12(1):6804. :Seiten (Pages):
Aus der Charité: Schmelz K, Toedling J, Cwikla MC, Kruetzfeldt LM, Proba J, Boral S, Lodrini M, Chen CY, Szymansky A, Astrahantseff K, Kuenkele A, Haase K, Deubzer HE, Hertwig F, Hundsdoerfer P, Henssen AG, Schulte JH, Eggert A.Autoren:Hey J et al.
Titel:Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease.
Zeitschrift (Journal):Nat Commun. 2021 Nov 11;12(1):6520. :Seiten (Pages):
Aus der Charité: Mall MA.Autoren:Nabi D et al.
Titel:CENP-V is required for proper chromosome segregation through interaction with spindle microtubules in mouse oocytes.
Zeitschrift (Journal):Nat Commun. 2021 Nov 11;12(1):6547. :Seiten (Pages):
Aus der Charité: Nabi D.
Oktober 2021
Autoren:Witkowski M et al.
Titel:Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells.
Zeitschrift (Journal):Nature. 2021 Oct 25. doi: 10.1038/s41586-021-04142-6. :Seiten (Pages):
Aus der Charité: Witkowski M, Tizian C, Niemeyer D, Jones TC, Frischbutter S, Angermair S, Hohnstein T, Mattiola I, Nawrath P, Mc Ewen S, Zocche S, Viviano E, Maurer M, Kölsch U, Chua RL, Aschman T, Meisel C, Radke J, Sawitzki B, Roehmel J, Allers K, Moos V, Schneider T, Hanitsch L, Mall MA, Conrad C, Radbruch H, Duerr CU, Corman VM, Kurth F, Sander LE, Drosten C, Treskatsch S, Diefenbach A.Autoren:Pietzner M et al.
Titel:Mapping the proteo-genomic convergence of human diseases.
Zeitschrift (Journal):Science. 2021 Oct 14:eabj1541. :Seiten (Pages):
Aus der Charité: Pietzner M, Langenberg C.Autoren:Tober-Lau P et al.
Titel:Long-term immunogenicity of BNT162b2 vaccination in older people and younger health-care workers.
Zeitschrift (Journal):Lancet Respir Med. 2021 Nov;9(11):e104-e105. :Seiten (Pages):
Aus der Charité: Tober-Lau P, Schwarz T, Hillus D, Suttorp N, Kappert K, Seybold J, Drosten C, Kurth F, Sander LE, Corman VM.Autoren:Haghikia A et al.
Titel:Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism.
Zeitschrift (Journal):Eur Heart J. 2021 Oct 1:ehab644. :Seiten (Pages):
Aus der Charité: Haghikia A, Zimmermann F, Schumann P, Jasina A, Roessler J, Schmidt D, Heinze P, Nageswaran V, Aigner A, Cineus R, Hegazy AN, Kränkel N, Leistner DM, Heimesaat MM, Bereswill S, Rauch G, Seeland U, Müller DN, Landmesser U.Autoren:Dahlmann M et al.
Titel:Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Zeitschrift (Journal):Mol Cancer. 2021 Oct 21;20(1):129. :Seiten (Pages):
Aus der Charité: Dahlmann M, Gambara G, Pachmayr E, Mokritzkij M, Gül-Klein S, Brandl A, Schweiger-Eisbacher C, Keilholz U, Walther W, Rau B, Stein U.Autoren:Schmid S et al.
Titel:Genetic and epigenetic characterization of posterior pituitary tumors.
Zeitschrift (Journal):Acta Neuropathol. 2021 Dec;142(6):1025-1043. :Seiten (Pages):
Aus der Charité: Schmid S, Perez E, Thieme A, Dittmayer C, Koch A, Capper D.Autoren:Krieger TG et al.
Titel:Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy.
Zeitschrift (Journal):Nat Commun. 2021 Oct 5;12(1):5826. :Seiten (Pages):
Aus der Charité: Krieger TG, Ten FW, Ishaque N, Jechow K, Debnath O, Eils R, Conrad C.Autoren:Budde K et al.
Titel:Conversion from Calcineurin Inhibitor to Belatacept-based Maintenance Immunosuppression in Renal Transplant Recipients: a Randomized Phase 3b Trial.
Zeitschrift (Journal):J Am Soc Nephrol. 2021 Oct 27:ASN.2021050628. :Seiten (Pages):
Aus der Charité: Budde K.Autoren:Schrezenmeier E et al.
Titel:B and T Cell Responses after a Third Dose of SARS-CoV-2 Vaccine in Kidney Transplant Recipients.
Zeitschrift (Journal):J Am Soc Nephrol. 2021 Oct 19:ASN.2021070966. :Seiten (Pages):
Aus der Charité: Schrezenmeier E, Rincon-Arevalo H, Stefanski AL, Staub-Hohenbleicher H, Choi M, Bachmann F, Pross V, Hammett C, Eckardt KU, Kotsch K, Döerner T, Budde K, Sattler A, Halleck F.Autoren:Heine J et al.
Titel:Long-Term Cognitive Outcome in Anti-N-Methyl-D-Aspartate Receptor Encephalitis.
Zeitschrift (Journal):Ann Neurol. 2021 Sep 30. doi: 10.1002/ana.26241. :Seiten (Pages):
Aus der Charité: Heine J, Kopp UA, Klag J, Ploner CJ, Prüss H, Finke C.
September 2021
Autoren:Lee S et al.
Titel:Virus-induced senescence is driver and therapeutic target in COVID-19.
Zeitschrift (Journal):Nature. 2021 Sep 13. doi: 10.1038/s41586-021-03995-1. :Seiten (Pages):
Aus der Charité: Lee S, Richter-Pechanska P, Belenki D, Kausche L, Niemeyer D, Mülleder M, Michaelis EG, Lau A, Schönlein M, Drosten C, Ralser M, Eils R, Reimann M, Fan DNY, Schmitt CA.Autoren:Loyal L et al.
Titel:Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination.
Zeitschrift (Journal):Science. 2021 Aug 31:eabh1823. :Seiten (Pages):
Aus der Charité: Loyal L, Braun J, Henze L, Kruse B, Dingeldey M, Reimer U, Kern F, Schwarz T, Mangold M, Unger C, Dörfler F, Kadler S, Rosowski J, Gürcan K, Uyar-Aydin Z, Frentsch M, Kurth F, Schnatbaum K, Eckey M, Hippenstiel S, Hocke A, Müller MA, Sawitzki B, Miltenyi S, Paul F, Mall MA, Wenschuh H, Voigt S, Drosten C, Lauster R, Lachman N, Sander LE, Corman VM, Röhmel J, Meyer-Arndt L, Thiel A, Giesecke-Thiel C.Autoren:Modest DP et al.
Titel:Panitumumab Plus Fluorouracil and Folinic Acid Versus Fluorouracil and Folinic Acid Alone as Maintenance Therapy in RAS Wild-Type Metastatic Colorectal Cancer: The Randomized PANAMA Trial (AIO KRK 0212).
Zeitschrift (Journal):J Clin Oncol. 2021 Sep 17:JCO2101332. :Seiten (Pages):
Aus der Charité: Modest DP, Kurreck A, Stahler A, Held S, Jarosch A, Horst D, Stintzing S.Autoren:Katsoulis M et al.
Titel:Identifying adults at high-risk for change in weight and BMI in England: a longitudinal, large-scale, population-based cohort study using electronic health records.
Zeitschrift (Journal):Lancet Diabetes Endocrinol. 2021 Oct;9(10):681-694. :Seiten (Pages):
Aus der Charité: Langenberg C.Autoren:Heyder NA et al.
Titel:Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide.
Zeitschrift (Journal):Cell Res. 2021 Sep 24. doi: 10.1038/s41422-021-00569-8. :Seiten (Pages):
Aus der Charité: Heyder NA, Kleinau G, Speck D, Schmidt A, Paisdzior S, Szczepek M, Bauer B, Koch A, Gallandi M, Kwiatkowski D, Bürger J, Hildebrand PW, Spahn CMT, Schacherl M, Biebermann H, Kühnen P, Kobilka BK, Scheerer P.Autoren:Bojarski C et al.
Titel:Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome.
Zeitschrift (Journal):Gut. 2021 Sep 20:gutjnl-2021-325181. :Seiten (Pages):
Aus der Charité: Bojarski C, Tangermann P, Barmeyer C, Buchkremer J, Roehle R, Daum S, Siegmund B, Schumann M, Ullrich R.Autoren:Steger M et al.
Titel:Time-resolved in vivo ubiquitinome profiling by DIA-MS reveals USP7 targets on a proteome-wide scale.
Zeitschrift (Journal):Nat Commun. 2021 Sep 13;12(1):5399. :Seiten (Pages):
Aus der Charité: Demichev V, Ralser M.Autoren:Schroeder S et al.
Titel:Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5.
Zeitschrift (Journal):Nat Commun. 2021 Sep 7;12(1):5324. :Seiten (Pages):
Aus der Charité: Schroeder S, Corman VM, Muth D, Richter A, Fatykhova D, Hocke A, Hippenstiel S, Müller MA, Drosten C.Autoren:Kreye J et al.
Titel:Encephalitis patient-derived monoclonal GABAA receptor antibodies cause epileptic seizures.
Zeitschrift (Journal):J Exp Med. 2021 Nov 1;218(11):e20210012. :Seiten (Pages):
Aus der Charité: Kreye J, Stöffler L, Machule ML, Reincke SM, Nikolaus M, van Hoof S, Sanchez-Sendin E, Homeyer MA, Cordero Gómez C, Kornau HC, Schmitz D, Kaindl AM, Boehm-Sturm P, Mueller S, Turko P, Vida I, Prüss H.Autoren:Demircan K et al.
Titel:Serum selenium, selenoprotein P and glutathione peroxidase 3 as predictors of mortality and recurrence following breast cancer diagnosis: A multicentre cohort study.
Zeitschrift (Journal):Redox Biol. 2021 Sep 21;47:102145. :Seiten (Pages):
Aus der Charité: Demircan K, Sun Q, Rijntjes E, Schomburg L.
August 2021
Autoren:Anker SD et al.
Titel:EMPEROR-Preserved Trial Investigators. Empagliflozin in Heart Failure with a Preserved Ejection Fraction.
Zeitschrift (Journal):N Engl J Med. 2021 Aug 27. doi: 10.1056/NEJMoa2107038 :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Barry PJ et al.
Titel:Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.
Zeitschrift (Journal):N Engl J Med. 2021 Aug 26;385(9):815-825 :Seiten (Pages):
Aus der Charité: Mall MA.Autoren:Loske J et al.
Titel:Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children.
Zeitschrift (Journal):Nat Biotechnol. 2021 Aug 18. doi: 10.1038/s41587-021-01037-9 :Seiten (Pages):
Aus der Charité: Loske J, Röhmel J, Lukassen S, Stricker S, Liebig J, Chua RL, Thürmann L, Messingschlager M, Seegebarth A, Ralser M, Sawitzki B, Sander LE, Corman VM, Conrad C, Trump S, Eils R, Mall MA, Lehmann I.Autoren:van Tilburg CM et al.
Titel:The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets.
Zeitschrift (Journal):Cancer Discov. 2021 Aug 9:candisc.0094.2021 :Seiten (Pages):
Aus der Charité: von Stackelberg A, Lissat A, Eggert A, Scheer M, Capper D.Autoren:Hillus D et al.
Titel:Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort study.
Zeitschrift (Journal):Lancet Respir Med. 2021 Aug 12:S2213-2600(21)00357-X :Seiten (Pages):
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Titel:Effect of Empagliflozin on Worsening Heart Failure Events in Patients with Heart Failure and a Preserved Ejection Fraction: The EMPEROR-Preserved Trial.
Zeitschrift (Journal):Circulation. 2021 Aug 29. doi: 10.1161/CIRCULATIONAHA.121.056824 :Seiten (Pages):
Aus der Charité: Doehner W, Anker SD.Autoren:Hernández DC et al.
Titel:An in vitro platform supports generation of human innate lymphoid cells from CD34+ hematopoietic progenitors that recapitulate ex vivo identity.
Zeitschrift (Journal):Immunity. 2021 Aug 24:S1074-7613(21)00307-1 :Seiten (Pages):
Aus der Charité: Hernández DC, Romagnani C.Autoren:Engelmann C et al.
Titel:Granulocyte-Colony Stimulating Factor (G-CSF) to treat acute-on-chronic liver failure, a multicenter randomized trial (GRAFT study).
Zeitschrift (Journal):J Hepatol. 2021 Aug 5:S0168-8278(21)01963-2 :Seiten (Pages):
Aus der Charité: Engelmann C, Mueller T, Schmelzle M, Splith K.Autoren:Goss CH et al.
Titel:Efficacy and safety of inhaled ENaC inhibitor BI 1265162 in patients with cystic fibrosis: BALANCE-CF™ 1 - a randomised, Phase II study.
Zeitschrift (Journal):Eur Respir J. 2021 Aug 12:2100746 :Seiten (Pages):
Aus der Charité: Mall MA.Autoren:Nouailles G et al.
Titel:Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19.
Zeitschrift (Journal):Nat Commun. 2021 Aug 11;12(1):4869 :Seiten (Pages):
Aus der Charité: Nouailles G, Pennitz P, Postmus D, Kazmierski J, Pott F, Muelleder M, Farztdinov V, Obermayer B, Wienhold SM, Sawitzki B, Drosten C, Sander LE, Suttorp N, Ralser M, Beule D, Goffinet C, Witzenrath M.
Juli 2021
Autoren:Bartels F et al.
Titel:Association Between Neuronal Autoantibodies and Cognitive Impairment in Patients With Lung Cancer.
Zeitschrift (Journal):JAMA Oncol. 2021 Jul 1:e212049. :Seiten (Pages):
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Titel:Magnetic Resonance Imaging Detects Progression of Lung Disease and Impact of Newborn Screening in Preschool Children with Cystic Fibrosis.
Zeitschrift (Journal):Am J Respir Crit Care Med. 2021 Jul 20. doi: 10.1164/rccm.202102-0278OC. :Seiten (Pages):
Aus der Charité: Stahl M, Steinke E, Graeber SY, Mall MA.Autoren:Karagiannidis C et al.
Titel:High In-Hospital Mortality in COVID Patients Receiving ECMO in Germany - A Critical Analysis.
Zeitschrift (Journal):Am J Respir Crit Care Med. 2021 Jul 20. doi: 10.1164/rccm.202105-1145LE. :Seiten (Pages):
Aus der Charité: Weber-Carstens S.Autoren:Kunz D et al.
Titel:Treatment of isolated REM-sleep behavior disorder using melatonin as a chronobiotic.
Zeitschrift (Journal):J Pineal Res. 2021 Jul 26:e12759. :Seiten (Pages):
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Titel:Disparities in Screening and Treatment of Cardiovascular Diseases in Patients With Mental Disorders Across the World: Systematic Review and Meta-Analysis of 47 Observational Studies.
Zeitschrift (Journal):Am J Psychiatry. 2021 Jul 14:appiajp202121010031. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Papadopoulos IN et al.
Titel:Dynamic conjugate F-SHARP microscopy.
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Aus der Charité: Papadopoulos IN, Judkewitz B.Autoren:Finger AM et al.
Titel:Intercellular coupling between peripheral circadian oscillators by TGF-β signaling.
Zeitschrift (Journal):Sci Adv. 2021 Jul 23;7(30):eabg5174. :Seiten (Pages):
Aus der Charité: Finger AM, Jäschke S, Del Olmo M, Granada AE, Herzel H, Kramer A.Autoren:Epifanova E et al.
Titel:Adhesion dynamics in the neocortex determine the start of migration and the post-migratory orientation of neurons.
Zeitschrift (Journal):Sci Adv. 2021 Jul 2;7(27):eabf1973. :Seiten (Pages):
Aus der Charité: Epifanova E, Salina V, Lajkó D, Textoris-Taube K, Naumann T, Bormuth O, Bormuth I, Horan S, Schaub T, Borisova E, Ambrozkiewicz MC, Tarabykin V, Rosário M.Autoren:Zirngibl F et al.
Titel:GD2-directed bispecific trifunctional antibody outperforms dinutuximab beta in a murine model for aggressive metastasized neuroblastoma.
Zeitschrift (Journal):J Immunother Cancer. 2021 Jul;9(7):e002923. :Seiten (Pages):
Aus der Charité: Zirngibl F, Ivasko SM, Grunewald L, Klaus A, Schwiebert S, Astrahantseff K, Andersch L, Schulte JH, Eggert A, Anders K, Hundsdoerfer P, Künkele A.Autoren:Chatchatee P et al.
Titel:Tolerance development in cow's milk-allergic infants receiving amino acid-based formula: A randomized controlled trial.
Zeitschrift (Journal):J Allergy Clin Immunol. 2021 Jul 2:S0091-6749(21)01053-8. :Seiten (Pages):
Aus der Charité: Trendelenburg V, Beyer K.
Juni 2021
Autoren:von Schwartzenberg RJ et al.
Titel:Caloric restriction disrupts the microbiota and colonization resistance.
Zeitschrift (Journal):Nature. 2021 Jun 23. doi: 10.1038/s41586-021-03663-4. :Seiten (Pages):
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Titel:Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.
Zeitschrift (Journal):Nat Biotechnol. 2021 Jun 3. doi: 10.1038/s41587-021-00927-2. :Seiten (Pages):
Aus der Charité: Ludwig LS.Autoren:Ghadjar P et al.
Titel:Dose-intensified Versus Conventional-dose Salvage Radiotherapy for Biochemically Recurrent Prostate Cancer After Prostatectomy: The SAKK 09/10 Randomized Phase 3 Trial.
Zeitschrift (Journal):Eur Urol. 2021 Jun 14:S0302-2838(21)01802-9. :Seiten (Pages):
Aus der Charité: Ghadjar P, Wust P.Autoren:Aschman T et al.
Titel:Association Between SARS-CoV-2 Infection and Immune-Mediated Myopathy in Patients Who Have Died.
Zeitschrift (Journal):JAMA Neurol. 2021 Jun 11. doi: 10.1001/jamaneurol.2021.2004. :Seiten (Pages):
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Titel:Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients.
Zeitschrift (Journal):Sci Immunol. 2021 Jun 15;6(60):eabj1031. :Seiten (Pages):
Aus der Charité: Rincon-Arevalo H, Choi M, Stefanski AL, Halleck F, Weber U, Szelinski F, Sattler A, Kotsch K, Chen Y, Burmester GR, Eckardt KU, Budde K, Mashreghi MF, Schrezenmeier E, Dörner T.Autoren:Peng Y et al.
Titel:Spatially structured inhibition defined by polarized parvalbumin interneuron axons promotes head direction tuning.
Zeitschrift (Journal):Sci Adv. 2021 Jun 16;7(25):eabg4693. :Seiten (Pages):
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Titel:SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Zeitschrift (Journal):Nat Commun. 2021 Jun 21;12(1):3818. :Seiten (Pages):
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Titel:Live-cell imaging of circadian clock protein dynamics in CRISPR-generated knock-in cells.
Zeitschrift (Journal):Nat Commun. 2021 Jun 18;12(1):3796. :Seiten (Pages):
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Titel:Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories.
Zeitschrift (Journal):Nat Commun. 2021 Jun 11;12(1):3576. :Seiten (Pages):
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Titel:E2F6 initiates stable epigenetic silencing of germline genes during embryonic development.
Zeitschrift (Journal):Nat Commun. 2021 Jun 11;12(1):3582. :Seiten (Pages):
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Mai 2021
Autoren:Jones TC et al.
Titel:Estimating infectiousness throughout SARS-CoV-2 infection course.
Zeitschrift (Journal):Science. 2021 May 25:eabi5273. :Seiten (Pages):
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Titel:Efficacy and acceptability of pharmacological, psychosocial, and brain stimulation interventions in children and adolescents with mental disorders: an umbrella review.
Zeitschrift (Journal):World Psychiatry. 2021 Jun;20(2):244-275. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Haeusler KG et al.
Titel:Systematic monitoring for detection of atrial fibrillation in patients with acute ischaemic stroke (MonDAFIS): a randomised, open-label, multicentre study.
Zeitschrift (Journal):Lancet Neurol. 2021 Jun;20(6):426-436. :Seiten (Pages):
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Titel:Finerenone Reduces Onset of Atrial Fibrillation in Patients with Chronic Kidney Disease and Type 2 Diabetes.
Zeitschrift (Journal):J Am Coll Cardiol. 2021 May 4:S0735-1097(21)04966-4. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Højlund M et al.
Titel:Standard versus reduced dose of antipsychotics for relapse prevention in multi-episode schizophrenia: a systematic review and meta-analysis of randomised controlled trials.
Zeitschrift (Journal):Lancet Psychiatry. 2021 Jun;8(6):471-486. :Seiten (Pages):
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Titel:Choose wisely: imaging for diagnosis of axial spondyloarthritis.
Zeitschrift (Journal):Ann Rheum Dis. 2021 May 28:annrheumdis-2021-220136. :Seiten (Pages):
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Titel:Fetal meconium does not have a detectable microbiota before birth.
Zeitschrift (Journal):Nat Microbiol. 2021 May 10. doi: 10.1038/s41564-021-00904-0. :Seiten (Pages):
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Titel:Association of a Marker of N-Acetylglucosamine With Progressive Multiple Sclerosis and Neurodegeneration.
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Titel:Cannabinoid receptor activation acutely increases synaptic vesicle numbers by activating synapsins in human synapses.
Zeitschrift (Journal):Mol Psychiatry. 2021 Apr 30. doi: 10.1038/s41380-021-01095-0. :Seiten (Pages):
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Titel:Role of angiopoietin-2 in venous thrombus resolution and chronic thromboembolic disease.
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April 2021
Autoren:Eckardt KU et al.
Titel:Safety and Efficacy of Vadadustat for Anemia in Patients Undergoing Dialysis.
Zeitschrift (Journal):N Engl J Med. 2021 Apr 29;384(17):1601-1612. :Seiten (Pages):
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Titel:Vadadustat in Patients with Anemia and Non-Dialysis-Dependent CKD.
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Titel:Control of endothelial quiescence by FOXO-regulated metabolites.
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Titel:Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised, cohort, and pre-post studies.
Zeitschrift (Journal):Lancet Psychiatry. 2021 May;8(5):387-404. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Siegert E et al.
Titel:Systemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology.
Zeitschrift (Journal):Acta Neuropathol. 2021 Apr 17. doi: 10.1007/s00401-021-02305-3. :Seiten (Pages):
Aus der Charité: Siegert E, Uruha A, Goebel HH, Preuße C, Casteleyn V, Kleefeld F, Burmester GR, Schneider U, Höppner J, Hahn K, Dittmayer C, Stenzel W.Autoren:Ferreira-Gomes M et al.
Titel:SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself.
Zeitschrift (Journal):Nat Commun. 2021 Mar 30;12(1):1961. :Seiten (Pages):
Aus der Charité: Tizian C, Pascual-Reguant A, Mothes R, Frischbutter S, Matz M, Ostendorf L, Maurer M, Schönrich G, Raftery M, Kallinich T, Mall MA, Angermair S, Treskatsch S, Dörner T, Corman VM, Diefenbach A, Volk HD, Elezkurtaj S, Hauser AE, Radbruch H, Witkowski M, Mashreghi MF.Autoren:Maifeld A et al.
Titel:Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients.
Zeitschrift (Journal):Nat Commun. 2021 Mar 30;12(1):1970. :Seiten (Pages):
Aus der Charité: Maifeld A, Bartolomaeus H, Löber U, Avery EG, Steckhan N, Markó L, Wilck N, Šušnjar U, Mähler A, Chen CY, Dechend R, Michalsen A, Müller DN, Forslund SK.Autoren:Qi S et al.
Titel:Reward Processing in Novelty Seekers: A Transdiagnostic Psychiatric Imaging Biomarker.
Zeitschrift (Journal):Biol Psychiatry. 2021 Jan 30:S0006-3223(21)00078-0. :Seiten (Pages):
Aus der Charité: Schumann G, Chu C, Quinlan EB, Desrivières S, Heinz A, Walter H.Autoren:Fritz F et al.
Titel:VirtualTaste: a web server for the prediction of organoleptic properties of chemical compounds.
Zeitschrift (Journal):Nucleic Acids Res. 2021 Apr 27:gkab292. :Seiten (Pages):
Aus der Charité: Fritz F, Preissner R, Banerjee P.Autoren:Steinhaus R et al.
Titel:MutationTaster2021.
Zeitschrift (Journal):Nucleic Acids Res. 2021 Apr 24:gkab266. :Seiten (Pages):
Aus der Charité: Steinhaus R, Proft S, Schuelke M, Schwarz JM, Seelow D.
März 2021
Autoren:Locatelli F et al.
Titel:Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial.
Zeitschrift (Journal):JAMA. 2021 Mar 2;325(9):843-854. :Seiten (Pages):
Aus der Charité: Eckert C, von Stackelberg A.Autoren:Messner CB et al.
Titel:Ultra-fast proteomics with Scanning SWATH.
Zeitschrift (Journal):Nat Biotechnol. 2021 Mar 25. doi: 10.1038/s41587-021-00860-4. :Seiten (Pages):
Aus der Charité: Messner CB, Demichev V, Freiwald A, Jürgens L, Suttorp N, Sander LE, Kurth F, Mülleder M, Ralser M.Autoren:Guigay J et al.
Titel:Cetuximab, docetaxel, and cisplatin versus platinum, fluorouracil, and cetuximab as first-line treatment in patients with recurrent or metastatic head and neck squamous-cell carcinoma (GORTEC 2014-01 TPExtreme): a multicentre, open-label, randomised, phase 2 trial.
Zeitschrift (Journal):Lancet Oncol. 2021 Apr;22(4):463-475. :Seiten (Pages):
Aus der Charité: Keilholz U.Autoren:Hagi K et al.
Titel:Association Between Cardiovascular Risk Factors and Cognitive Impairment in People With Schizophrenia: A Systematic Review and Meta-analysis.
Zeitschrift (Journal):JAMA Psychiatry. 2021 Mar 3:e210015. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Thomas C et al.
Titel:TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma.
Zeitschrift (Journal):Acta Neuropathol. 2021 Mar 23. doi: 10.1007/s00401-021-02300-8. :Seiten (Pages):
Aus der Charité: Träger M, Förster A, Geiler C, Onken J, Vajkoczy P, Heppner FL, Capper D, Koch A, Kaul D, Schweizer L.Autoren:Inak G et al.
Titel:Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Zeitschrift (Journal):Nat Commun. 2021 Mar 26;12(1):1929. :Seiten (Pages):
Aus der Charité: Secker C, Zink A, Henke MT, Priller J, Stenzel W, Schuelke M.Autoren:Pascual-Reguant A et al.
Titel:Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells.
Zeitschrift (Journal):Nat Commun. 2021 Mar 19;12(1):1737. :Seiten (Pages):
Aus der Charité: Pascual-Reguant A, Mothes R, Uecker R, Kotsch K, Romagnani C, Hauser AE.Autoren:Schiweck J et al.
Titel:Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking.
Zeitschrift (Journal):Nat Commun. 2021 Mar 5;12(1):1490. :Seiten (Pages):
Aus der Charité: Schiweck J, Murk K, Ledderose J, Münster-Wandowski A, Ornaghi M, Vida I, Eickholt BJ.Autoren:Brisson NM et al.
Titel:Association of machine learning based predictions of medial knee contact force with cartilage loss over 2.5 years in knee osteoarthritis.
Zeitschrift (Journal):Arthritis Rheumatol. 2021 Mar 24. doi: 10.1002/art.41735. :Seiten (Pages):
Aus der Charité: Brisson NM, Damm P, Duda GN.Autoren:Rasche A et al.
Titel:A hepatitis B virus causes chronic infections in equids worldwide.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2013982118. :Seiten (Pages):
Aus der Charité: Rasche A, Goldmann N, Moreira-Soto A, de Oliveira Carneiro I, Drexler JF.Autoren:Waterstraat G et al.
Titel:Noninvasive neuromagnetic single-trial analysis of human neocortical population spikes.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2017401118. :Seiten (Pages):
Aus der Charité: Waterstraat G, Curio G.
Febuar 2021
Autoren:Ebinger M et al.
Titel:Association Between Dispatch of Mobile Stroke Units and Functional Outcomes Among Patients With Acute Ischemic Stroke in Berlin.
Zeitschrift (Journal):JAMA. 2021 Feb 2;325(5):454-466. :Seiten (Pages):
Aus der Charité:Ebinger M, Siegerink B, Kunz A, Weber JE, Geisler F, Freitag E, Lange J, Behrens J, Erdur H, Ganeshan R, Liman T, Scheitz JF, Schlemm L, Harmel P, Lorenz-Meyer I, Napierkowski I, Waldschmidt C, Nolte CH, Grittner U, Wiener E, Bohner G, Rohmann JL, Endres M, Audebert HJ.Autoren:Allou L et al.
Titel:Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator.
Zeitschrift (Journal):Nature. 2021 Feb 10. doi: 10.1038/s41586-021-03208-9. :Seiten (Pages):
Aus der Charité: Allou L, Magg A, Schöpflin R, Chan WL, Spielmann M, Cova G, Mundlos S.Autoren:Schmalbrock LK et al.
Titel:Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Zeitschrift (Journal):Blood. 2021 Feb 17:blood.2020007626. :Seiten (Pages):
Aus der Charité: Dolnik A, Sträng E, Bullinger L.Autoren:Nikolay R et al.
Titel:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Zeitschrift (Journal):Mol Cell. 2021 Feb 23:S1097-2765(21)00092-7. :Seiten (Pages):
Aus der Charité: Nikolay R, Hilal T, Qin B, Schwefel D, Bürger J, Loerke J, Flügel T, Selbach M, Spahn CMT.Autoren:Salomon JJ et al.
Titel:Chronic Rhinosinusitis with Nasal Polyps is Associated with Impaired TMEM16A-mediated Epithelial Chloride Secretion.
Zeitschrift (Journal):J Allergy Clin Immunol. 2021 Feb 17:S0091-6749(21)00224-4. :Seiten (Pages):
Aus der Charité: Graeber SY, Mall MA.Autoren:Agostini F et al.
Titel:Multiomics Analysis Provides Insight into the Laboratory Evolution of Escherichia coli toward the Metabolic Usage of Fluorinated Indoles.
Zeitschrift (Journal):ACS Cent Sci. 2021 Jan 27;7(1):81-92. :Seiten (Pages):
Aus der Charité: Agostini F.Autoren:Mencacci NE et al.
Titel:Bi-allelic variants in TSPOAP1, encoding the active zone protein RIMBP1, cause autosomal recessive dystonia.
Zeitschrift (Journal):J Clin Invest. 2021 Feb 4:140625. :Seiten (Pages):
Aus der Charité: Brockmann MM, Rosenmund C.Autoren:Dong P et al.
Titel:A Dual Fluorescence-Spin Label Probe for Visualization and Quantification of Target Molecules in Tissue by Multiplexed FLIM - EPR Spectroscopy.
Zeitschrift (Journal):Angew Chem Int Ed Engl. 2021 Feb 5. doi: 10.1002/anie.202012852. :Seiten (Pages):
Aus der Charité: Dong P, Lohan SB, Patzelt A, Meinke MC.Autoren:Iftekhar A et al.
Titel:Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
Zeitschrift (Journal):Nat Commun. 2021 Feb 12;12(1):1003. :Seiten (Pages):
Aus der Charité: Berger H, Heuberger J, Sigal M.Autoren:Niehus S et al.
Titel:PopDel identifies medium-size deletions simultaneously in tens of thousands of genomes.
Zeitschrift (Journal):Nat Commun. 2021 Feb 1;12(1):730. :Seiten (Pages):
Aus der Charité: Niehus S, Sulem P, Kehr B.
Januar 2021
Autoren:Lotta LA et al.
Titel:A cross-platform approach identifies genetic regulators of human metabolism and health.
Zeitschrift (Journal):Nat Genet. 2021 Jan;53(1):54-64. :Seiten (Pages):
Aus der Charité: Langenberg C.Autoren:Vollmer T et al.
Titel:The intratumoral CXCR3 chemokine system is predictive of chemotherapy response in human bladder cancer.
Zeitschrift (Journal):Sci Transl Med. 2021 Jan 13;13(576):eabb3735. :Seiten (Pages):
Aus der Charité: Vollmer T, Schlickeiser S, Amini L, Schulenberg S, Wendering DJ, Jurisch A, Noster R, Kunkel D, Brindle NR, Savidis I, Akyüz L, Roch T, Babel N, Reinke P, Volk HD, Schmueck-Henneresse M.Autoren:Westhovens R et al.
Titel:Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial.
Zeitschrift (Journal):Ann Rheum Dis. 2021 Jan 15:annrheumdis-2020-219213. :Seiten (Pages):
Aus der Charité: Burmester GR .Autoren:Deshpande D et al.
Titel:Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy.
Zeitschrift (Journal):Nat Commun. 2021 Jan 18;12(1):426. :Seiten (Pages):
Aus der Charité: Deshpande D, Klose CSN.Autoren:Rodríguez de Los Santos M et al.
Titel:A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):e2014481118. :Seiten (Pages):
Aus der Charité: Rodríguez de Los Santos M, Rivalan M, Stumpf A, Velasquez LM, Voigt A, Long M, Vogt G, Fischer-Zirnsak B, Horn D, Mundlos S, Kornak U, Schmitz D, Winter Y.Autoren:Horn D et al.
Titel:Biallelic truncating variants in MAPKAPK5 cause a new developmental disorder involving neurological, cardiac, and facial anomalies combined with synpolydactyly.
Zeitschrift (Journal):Genet Med. 2021 Jan 13. doi: 10.1038/s41436-020-01052-2. :Seiten (Pages):
Aus der Charité: Horn D, Schwartzmann S, Ehmke N, Boschann F.Autoren:Cheret C et al.
Titel:Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.
Zeitschrift (Journal):Cell Rep. 2021 Jan 12;34(2):108623. :Seiten (Pages):
Aus der Charité: Cheret C, Ahnert-Hilger G.Autoren:Lipp T et al.
Titel:Heterogeneity of Pollen Food Allergy Syndrome in Seven Southern European Countries: the @IT.2020 Multicenter Study.
Zeitschrift (Journal):Allergy. 2021 Jan 25. doi: 10.1111/all.14742. :Seiten (Pages):
Aus der Charité: Lipp T, Hoffmann TM, Potapova E, Matricardi PM, Dramburg S.Autoren:Simsek C et al.
Titel:At Least Seven Distinct Rotavirus Genotype Constellations in Bats with Evidence of Reassortment and Zoonotic Transmissions.
Zeitschrift (Journal):mBio. 2021 Jan 19;12(1):e02755-20. :Seiten (Pages):
Aus der Charité: Corman VM, Rasche A, Drosten C, Drexler JF, Matthijnssens J.Autoren:Wolk K et al.
Titel:Activity and components of the G-CSF pathway in hidradenitis suppurativa.
Zeitschrift (Journal):Br J Dermatol. 2021 Jan 5. doi: 10.1111/bjd.19795. :Seiten (Pages):
Aus der Charité: Wolk K, Brembach TC, Cucinotta S, Pokrywka A, Irmer ML, Triebus J, Witte-Händel E, Volk HD, Ghoreschi K, Sabat R.
Publikationen 2020
Dezember 2020
Autoren:Veenvliet JV et al.
Titel:Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites.
Zeitschrift (Journal):Science. 2020 Dec 11;370(6522):eaba4937. :Seiten (Pages):
Aus der Charité: Herrmann BG.Autoren:Trump S et al.
Titel:Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19.
Zeitschrift (Journal):Nat Biotechnol. 2020 Dec 24. doi: 10.1038/s41587-020-00796-1. :Seiten (Pages):
Aus der Charité: Trump S, Lukassen S, Anker MS, Chua RL, Liebig J, Thürmann L, Corman VM, Loske J, Krieger T, Hennig BP, Messingschlager M, Pott F, Kazmierski J, Twardziok S, Albrecht JP, Eils J, Hadzibegovic S, Lena A, Heidecker B, Bürgel T, Steinfeldt J, Goffinet C, Kurth F, Witzenrath M, Ishaque N, Sander LE, Drosten C, Eils R, Conrad C, Landmesser U, Lehmann I.Autoren:Abraham WT et al.
Titel:Effect of empagliflozin on exercise ability and symptoms in heart failure patients with reduced and preserved ejection fraction, with and without type 2 diabetes.
Zeitschrift (Journal):Eur Heart J. 2020 Dec 22:ehaa943. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Meinhardt J et al.
Titel:Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.
Zeitschrift (Journal):Nat Neurosci. 2020 Nov 30. doi: 10.1038/s41593-020-00758-5. :Seiten (Pages):
Aus der Charité: Meinhardt J, Radke J, Dittmayer C, Mothes R, Schneider J, Brünink S, Greuel S, Lehmann M, Hassan O, Aschman T, Schumann E, Chua RL, Conrad C, Eils R, Stenzel W, Windgassen M, Rößler L, Goebel HH, Martin H, Scheibe F, Körtvélyessy P, Siegmund B, Kühl AA, Elezkurtaj S, Horst D, Oesterhelweg L, Tsokos M, Drosten C, Corman VM, Radbruch H, Heppner FL.Autoren:Kraushar ML et al.
Titel:Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.
Zeitschrift (Journal):Mol Cell. 2020 Dec 17:S1097-2765(20)30837-6. :Seiten (Pages):
Aus der Charité: Kraushar ML, Krupp F, Turko P, Ambrozkiewicz MC, Sprink T, Schaub T, Münster-Wandowski A, Bürger J, Yamamoto H, Tarabykin V, Vida I, Spahn CMT.Autoren:Piepoli MF et al.
Titel:OUTSTEP-HF: randomised controlled trial comparing short-term effects of sacubitril/valsartan versus enalapril on daily physical activity in patients with chronic heart failure with reduced ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Dec 13. doi: 10.1002/ejhf.2076. :Seiten (Pages):
Aus der Charité: Edelmann F.Autoren:Anker SD et al.
Titel:Baseline Characteristics of Patients with Heart Failure with Preserved Ejection Fraction in the EMPEROR-Preserved Trial.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Nov 29. doi: 10.1002/ejhf.2064. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Grinat J et al.
Titel:The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Zeitschrift (Journal):Nat Commun. 2020 Dec 21;11(1):6422. :Seiten (Pages):
Aus der Charité: Heuberger J.Autoren:Pietzner M et al.
Titel:Genetic architecture of host proteins involved in SARS-CoV-2 infection.
Zeitschrift (Journal):Nat Commun. 2020 Dec 16;11(1):6397. :Seiten (Pages):
Aus der Charité: Ralser M, Langenberg C.Autoren:Loyal L et al.
Titel:SLAMF7 and IL-6R define distinct cytotoxic versus helper memory CD8+ T cells.
Zeitschrift (Journal):Nat Commun. 2020 Dec 11;11(1):6357. :Seiten (Pages):
Aus der Charité: Loyal L, Warth S, Jürchott K, Nikolaou C, Nienen M, Durlanik S, Kruse B, Frentsch M, Sabat R, Wolk K, Thiel A.
November 2020
Autoren:Clément K et al.
Titel:Setmelanotide POMC and LEPR Phase 3 Trial Investigators. Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.
Zeitschrift (Journal):Lancet Diabetes Endocrinol. 2020 Dec;8(12):960-970. :Seiten (Pages):
Aus der Charité: Puder L, Kühnen P.Autoren:Anker SD et al.
Titel:EMPEROR-Reduced Trial Committees and Investigators. Effect of Empagliflozin on Cardiovascular and Renal Outcomes in Patients With Heart Failure by Baseline Diabetes Status - Results from the EMPEROR-Reduced Trial.
Zeitschrift (Journal):Circulation. 2020 Nov 11. doi: 10.1161/CIRCULATIONAHA.120.051824. :Seiten (Pages):
Aus der Charité: Anker SD.Autoren:Guendel F et al.
Titel:Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues.
Zeitschrift (Journal):Immunity. 2020 Nov 17;53(5):1015-1032.e8. :Seiten (Pages):
Aus der Charité: Guendel F, Kofoed-Branzk M, Gronke K, Tizian C, Witkowski M, Brachs S, Mashreghi MF, Diefenbach A.Autoren:Tosti L et al.
Titel:Single nucleus and in situ RNA sequencing reveals cell topographies in the human pancreas.
Zeitschrift (Journal):Gastroenterology. 2020 Nov 16:S0016-5085(20)35399-3. :Seiten (Pages):
Aus der Charité: Tosti L, Debnath O, Tiesmeyer S, Trefzer T, Ten FW, Lukassen S, Kühl AA, Spieckermann S, Ishaque N, Eils R, Conrad C.Autoren:McVey MJ et al.
Titel:Platelet Extracellular Vesicles mediate Transfusion-related Acute Lung Injury by imbalancing the Sphingolipid Rheostat.
Zeitschrift (Journal):Blood. 2020 Nov 24:blood.2020005985. :Seiten (Pages):
Aus der Charité: Weidenfeld S, Tabuchi A, Simmons S, Kuebler W.Autoren:Reimann M et al.
Titel:Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Zeitschrift (Journal):Blood. 2020 Nov 24:blood.2020005244. :Seiten (Pages):
Aus der Charité: Reimann M, Schrezenmeier JF, Richter-Pechanska P, Dolnik A, Hick TP, Schleich K, Cai X, Fan DNY, Masswig S, Denker S, Busse A, Gätjens-Sanchez AM, Bullinger L.Autoren:Dejaco C et al.
Titel:Influence of COVID-19 pandemic on decisions for the management of people with inflammatory rheumatic and musculoskeletal diseases: a survey among EULAR countries.
Zeitschrift (Journal):Ann Rheum Dis. 2020 Nov 6:annrheumdis-2020-218697. :Seiten (Pages):
Aus der Charité: Buttgereit F.Autoren:Holstein J et al.
Titel:Immunophenotyping in pemphigus reveals a Th17/Tfh17-dominated immune response promoting desmoglein1/3-specific autoantibody production.
Zeitschrift (Journal):J Allergy Clin Immunol. 2020 Nov 19:S0091-6749(20)31624-9. :Seiten (Pages):
Aus der Charité: Solimani F, Meier K, Ghoreschi K.Autoren:Anker MS et al.
Titel:Ventricular tachycardia, premature ventricular contractions, and mortality in unselected patients with lung, colon, or pancreatic cancer: a prospective study.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Nov 22. doi: 10.1002/ejhf.2059. :Seiten (Pages):
Aus der Charité: Anker MS, Riess H, Eucker J, Haverkamp W, Landmesser U, Anker SD.Autoren:Lebenheim L et al.
Titel:A novel giant non-cholinergic striatal interneuron restricted to the ventrolateral striatum coexpresses Kv3.3 potassium channel, parvalbumin, and the vesicular GABA transporter.
Zeitschrift (Journal):Mol Psychiatry. 2020 Nov 14. doi: 10.1038/s41380-020-00948-4. :Seiten (Pages):
Aus der Charité: Lebenheim L, Booker SA, Derst C, Weiss T, Wagner F, Gruber C, Vida I, Veh RW.
Oktober 2020
Autoren:M Real F et al.
Titel:The mole genome reveals regulatory rearrangements associated with adaptive intersexuality.
Zeitschrift (Journal):Science. 2020 Oct 9;370(6513):208-214. :Seiten (Pages):
Aus der Charité: M Real F, Schöpflin R, Schindler M, Mundlos S, Lupiáñez DG.Autoren:Kreye J et al.
Titel:A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Zeitschrift (Journal):Cell. 2020 Sep 23:S0092-8674(20)31246-0. :Seiten (Pages):
Aus der Charité: Kreye J, Reincke SM, Kornau HC, Sánchez-Sendin E, Corman VM, Höltje M, Stöffler L, von Wardenburg N, van Hoof S, Homeyer MA, Hoffmann J, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Müller MA, Drosten C, Wendisch D, Sander LE, Prüss H.Autoren:Roemhild A et al.
Titel:Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial.
Zeitschrift (Journal):BMJ. 2020 Oct 21;371:m3734. :Seiten (Pages):
Aus der Charité: Roemhild A, Otto NM, Moll G, Abou-El-Enein M, Kaiser D, Bold G, Schachtner T, Choi M, Oellinger R, Landwehr-Kenzel S, Juerchott K, Sawitzki B, Giesler C, Sefrin A, Beier C, Wagner DL, Schlickeiser S, Streitz M, Schmueck-Henneresse M, Amini L, Babel N, Volk HD, Reinke P.Autoren:Leistner DM et al.
Titel:Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study.
Zeitschrift (Journal):Eur Heart J. 2020 Oct 1;41(37):3549-3560. :Seiten (Pages):
Aus der Charité: Leistner DM, Kränkel N, Meteva D, Abdelwahed YS, Seppelt C, Stähli BE, Skurk C, Lauten A, Mochmann HC, Fröhlich G, Rauch-Kröhnert U, Flores E, Riedel M, Sieronski L, Kia S, Strässler E, Haghikia A, Dirks F, Steiner JK, Mueller DN, Volk HD, Klotsche J, Landmesser U.Autoren:Fujikura K et al.
Titel:Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic KLF4 mutations predominantly in low-grade regions.
Zeitschrift (Journal):Gut. 2020 Oct 7:gutjnl-2020-321217. :Seiten (Pages):
Aus der Charité: Felsenstein M.Autoren:Schoon J et al.
Titel:Metal-Specific Biomaterial Accumulation in Human Peri-Implant Bone and Bone Marrow.
Zeitschrift (Journal):Adv Sci (Weinh). 2020 Aug 3;7(20):2000412. :Seiten (Pages):
Aus der Charité: Schoon J, Rakow A, Ort MJ, Jacobi D, Reinke S, Perka C, Duda GN, Geissler S.Autoren:Cohen SB et al.
Titel:Safety profile of upadacitinib in rheumatoid arthritis: integrated analysis from the SELECT phase III clinical programme.
Zeitschrift (Journal):Ann Rheum Dis. 2020 Oct 28:annrheumdis-2020-218510. :Seiten (Pages):
Aus der Charité: Burmester GR.Autoren:Zuraw B et al.
Titel:Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: a randomized, double-blind, placebo-controlled phase 3 trial.
Zeitschrift (Journal):J Allergy Clin Immunol. 2020 Oct 21:S0091-6749(20)31484-6. :Seiten (Pages):
Aus der Charité: Maurer M.Autoren:Koehler J et al.
Titel:Telemonitoring in patients with chronic heart failure and moderate depressed symptoms: results of the Telemedical Interventional Monitoring in Heart Failure (TIM-HF) study.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Oct 15. doi: 10.1002/ejhf.2025. :Seiten (Pages):
Aus der Charité: Koehler J, Stengel A, Hofmann T, Koehler K, Rose M, Deckwart O, Anker SD, Koehler F.Autoren:Ballhausen A et al.
Titel:Phase I study of everolimus, letrozole, and trastuzumab in patients with hormone receptor-positive metastatic breast cancer or other solid tumors.
Zeitschrift (Journal):Clin Cancer Res. 2020 Oct 28:clincanres.2878.2020. :Seiten (Pages):
Aus der Charité: Ballhausen A.
September 2020
Autoren:Ostendorf L et al.
Titel:Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus.
Zeitschrift (Journal):N Engl J Med. 2020 Sep 17;383(12):1149-1155. :Seiten (Pages):
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Titel:Vitamin A controls the allergic response through T follicular helper cell as well as plasmablast differentiation.
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August 2020
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Titel:IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
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Titel:Randomized Comparison of Pazopanib and Doxorubicin as First-Line Treatment in Patients With Metastatic Soft Tissue Sarcoma Age 60 Years or Older: Results of a German Intergroup Study.
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Titel:Effects of Olanzapine Combined With Samidorphan on Weight Gain in Schizophrenia: A 24-Week Phase 3 Study.
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Titel:The human liver matrisome - Proteomic analysis of native and fibrotic human liver extracellular matrices for organ engineering approaches.
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Juli 2020
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Titel:Continuing versus tapering glucocorticoids after achievement of low disease activity or remission in rheumatoid arthritis (SEMIRA): a double-blind, multicentre, randomised controlled trial.
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Titel:Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age.
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Titel:TWIST1 Drives Smooth Muscle Cell Proliferation in Pulmonary Hypertension via Loss of GATA-6 and BMPR2.
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Titel:Comparison of Organoid Swelling and in vivo Biomarkers of CFTR Function to Determine Effects of Lumacaftor-ivacaftor in Patients with Cystic Fibrosis Homozygous for the F508del Mutation.
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Titel:Hypoxic-Ischemic Encephalopathy Evaluated by Brain Autopsy and Neuroprognostication After Cardiac Arrest.
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Titel:Association of Migraine With Aura and Other Risk Factors With Incident Cardiovascular Disease in Women.
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Titel:GFR in Healthy Aging: an Individual Participant Data Meta-Analysis of Iohexol Clearance in European Population-Based Cohorts.
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Mai 2020
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Titel:Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
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Titel:Virological assessment of hospitalized patients with COVID-2019.
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Titel:Functional consequences of metabolic zonation in murine livers: New insights for an old story.
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Titel:Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.
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Titel:Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway.
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Titel:Performance of immune-based and microbiological tests in children with TB meningitis in Europe - a multi-center Paediatric Tuberculosis Network European Trials Group (ptbnet) study.
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März 2020
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Titel:Heart-Specific Immune Responses in an Animal Model of AutoimmuneRelated Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation.
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Titel:Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity.
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Titel:Complement deposition at the neuromuscular junction in seronegative myasthenia gravis.
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Titel:Association of Magnetoencephalographically Measured High-Frequency Oscillations in Visual Cortex With Circuit Dysfunctions in Local and Large-scale Networks During Emerging Psychosis.
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Titel:MT-102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2020 Feb 17. doi: 10.1002/jcsm.12537. :Seiten (Pages):
Aus der Charité: Ishida J, Palus S, Tschirner A, Döhner W, Anker SD, Springer J.Autoren:Eede P et al.
Titel:Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.
Zeitschrift (Journal):EMBO Rep. 2020 Mar 4;21(3). doi: 10.15252/embr.201948530. :Seiten (Pages):
Aus der Charité: Eede P, Obst J, Benke E, Yvon-Durocher G, Richard BC, Gimber N, Schmoranzer J, Prokop S, Heppner FL.Autoren:Weber D et al.
Titel:Plasma carotenoids, tocopherols and retinol - Association with age in the Berlin Aging Study II.
Zeitschrift (Journal):Redox Biol. 2020 Feb 13;32:101461. :Seiten (Pages):
Aus der Charité: Demuth I, Steinhagen-Thiessen E, Norman K.Autoren:Booker SA et al.
Titel:Presynaptic GABAB receptors functionally uncouple somatostatin interneurons from the active hippocampal network.
Zeitschrift (Journal):Elife. 2020 Feb 19;9:e51156. :Seiten (Pages):
Aus der Charité: Booker SA, Vida I.Autoren:Tizian C et al.
Titel:c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells.
Zeitschrift (Journal):Elife. 2020 Feb 10;9:e52549. :Seiten (Pages):
Aus der Charité: Tizian C, Hölsken O, Cosovanu C, Kofoed-Branzk M, Diefenbach A, Neumann C.Autoren:Hotter B et al.
Titel:Inflammatory and stress markers predicting pneumonia, outcome, and etiology in patients with stroke: Biomarkers for predicting pneumonia, functional outcome, and death after stroke.
Zeitschrift (Journal):Neurol Neuroimmunol Neuroinflamm. 2020 Feb 25;7(3):e692. :Seiten (Pages):
Aus der Charité: Hotter B, Hoffmann S, Ulm L, Meisel C, Meisel A.Autoren:Weilnhammer V et al.
Titel:Psychotic Experiences in Schizophrenia and Sensitivity to Sensory Evidence.
Zeitschrift (Journal):Schizophr Bull. 2020 Feb 24:sbaa003. :Seiten (Pages):
Aus der Charité: Weilnhammer V, Röd L, Eckert AL, Stuke H, Heinz A, Sterzer P.Autoren:Roßberg S et al.
Titel:Orally applied bacterial lysate in infants at risk for atopy does not prevent atopic dermatitis, allergic rhinitis, asthma or allergic sensitization at school age: follow-up of a randomized trial.
Zeitschrift (Journal):Allergy. 2020 Feb 22. doi: 10.1111/all.14247. :Seiten (Pages):
Aus der Charité: Roßberg S, Keller T, Icke K, Keil T, Lau S.
Januar 2020
Autoren:Gidon A et al.
Titel:Dendritic action potentials and computation in human layer 2/3 cortical neurons.
Zeitschrift (Journal):Science. 2020 Jan 3;367(6473):83-87. :Seiten (Pages):
Aus der Charité: Fidzinski P, Bolduan F, Holtkamp M, Vida I, Larkum ME.Autoren:Correll CU et al.
Titel:Metformin add-on vs. antipsychotic switch vs. continued antipsychotic treatment plus healthy lifestyle education in overweight or obese youth with severe mental illness: results from the IMPACT trial.
Zeitschrift (Journal):World Psychiatry. 2020 Feb;19(1):69-80. :Seiten (Pages):
Aus der Charité: Correll CU, Kapoor S.Autoren:Barz MJ et al.
Titel:Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia.
Zeitschrift (Journal):Blood. 2020 Jan 22. doi: 10.1182/blood.2019002499. :Seiten (Pages):
Aus der Charité: Barz MJ, Hof J, Groeneveld-Krentz S, Astrahantseff K, von Stackelberg A.Autoren:Correll CU et al.
Titel:Efficacy and Safety of Lumateperone for Treatment of Schizophrenia: A Randomized Clinical Trial.
Zeitschrift (Journal):Blood. 2020 Jan 22. doi: 10.1182/blood.2019002499. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Ratziu V et al.
Titel:Cenicriviroc Treatment for Adults with Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study.
Zeitschrift (Journal):Hepatology. 2020 Jan 13:10.1002/hep.31108. :Seiten (Pages):
Aus der Charité: Tacke F.Autoren:Schürmann D et al.
Titel:Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial.
Zeitschrift (Journal):Lancet HIV. 2020;S2352-3018(19)30372-8. :Seiten (Pages):
Aus der Charité: Schürmann D, Keicher C, Huser A, Hofmann J.Autoren:Bartels F et al.
Titel:Neuronal autoantibodies associated with cognitive impairment in melanoma patients.
Zeitschrift (Journal):Ann Oncol. 2019 May 1;30(5):823-829. :Seiten (Pages):
Aus der Charité: Bartels F, Stronisch T, Farmer K, Kiecker F, Finke C.Autoren:Stintzing S et al.
Titel:Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial.
Zeitschrift (Journal):Ann Oncol. 2019 Nov 1;30(11):1796-1803. :Seiten (Pages):
Aus der Charité: Stintzing S.Autoren:Petutschnigg J et al.
Titel:Body fat phenotypes and treatment response to spironolactone in ambulatory patients with heart failure and preserved ejection fraction: a post-hoc analysis of the Aldo-DHF trial.
Zeitschrift (Journal):Eur J Heart Fail. 2020 Jan 7:10.1002/ejhf.1723. :Seiten (Pages):
Aus der Charité: Petutschnigg J, Trippel TD, Hashemi D, Pieske B, Edelmann F.Autoren:Scheffel J et al.
Titel:Cold-induced urticarial autoinflammatory syndrome related to factor XII activation.
Zeitschrift (Journal):Nat Commun. 2020 Jan 10;11(1):179. :Seiten (Pages):
Aus der Charité: Scheffel J, Mahnke NA, Wu J, Bonnekoh H, Church MK, Maurer M, Krause K.
Publikationen 2019
Dezember 2019
Autoren:Stahn AC et al.
Titel:Brain Changes in Response to Long Antarctic Expeditions.
Zeitschrift (Journal):N Engl J Med. 2019 Dec 5;381(23):2273-2275. :Seiten (Pages):
Aus der Charité: Stahn AC, Gunga HC.Autoren:Deodhar A et al.
Titel:Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial.
Zeitschrift (Journal):Lancet. 2020 Jan 4;395(10217):53-64. :Seiten (Pages):
Aus der Charité: Poddubnyy D, Sieper J.Autoren:Koche RP et al.
Titel:Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Zeitschrift (Journal):Nat Genet. 2019 Dec 16;10.1038/s41588-019-0547-z. :Seiten (Pages):
Aus der Charité: Helmsauer K, MacArthur IC, Chamorro R, Munoz-Perez N, Dorado Garcia H, Bei Y, Röefzaad C, Bardinet V, Szymansky A, Winkler A, Thole T, Timme N, Fuchs S, Klironomos F, Schmelz K, Künkele A, Hundsdörfer P, Deubzer H, Toedling J, Hertwig F, Eggert A, Schulte JH, Henssen AG.Autoren:Solmi M et al.
Titel:Disparities in cancer screening in people with mental illness across the world versus the general population: prevalence and comparative meta-analysis including 4,717,839 people.
Zeitschrift (Journal):Lancet Psychiatry. 2020 Jan;7(1):52-63. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Stintzing S et al.
Titel:Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial.
Zeitschrift (Journal):Ann Oncol. 2019 Nov 1;30(11):1796-1803. :Seiten (Pages):
Aus der Charité: Stintzing S.Autoren:Möckel M et al.
Titel:Improve Management of acute heart failure with ProcAlCiTonin in EUrope: results of the randomized clinical trial IMPACT EU Biomarkers in Cardiology (BIC) 18.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Dec 12. doi: 10.1002/ejhf.1667. :Seiten (Pages):
Aus der Charité: Möckel M, Slagman AC.Autoren:Pieske B et al.
Titel:Baseline features of the VICTORIA (Vericiguat Global Study in Subjects with Heart Failure with Reduced Ejection Fraction) trial.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Dec;21(12):1596-1604. :Seiten (Pages):
Aus der Charité: Pieske B et al..Autoren:Marg A et al.
Titel:Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
Zeitschrift (Journal):Nat Commun. 2019 Dec 18;10(1):5776. :Seiten (Pages):
Aus der Charité: Marg A, Escobar H, Grunwald SA, Metzler E, Kieshauer J, Pasemann D, Schneider J, Schülke M, Spuler S.Autoren:Ziegler JF et al.
Titel:Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease.
Zeitschrift (Journal):Nat Commun. 2019 Dec 10;10(1):5629. :Seiten (Pages):
Aus der Charité: Ziegler JF, Böttcher C, Letizia M, Yerinde C, Wu H, Freise I, Rodriguez-Sillke Y, Stoyanova AK, Kreis ME, Asbach P, Kunkel D, Priller J, Anagnostopoulos I, Kühl AA, Bojarski C, Glauben R, Siegmund B, Weidinger C.Autoren:Gusic M et al.
Titel:Bi-Allelic UQCRFS1 Variants Are Associated with Mitochondrial Complex III Deficiency, Cardiomyopathy, and Alopecia Totalis.
Zeitschrift (Journal):Am J Hum Genet. 2020 Jan 2;106(1):102-111. :Seiten (Pages):
Aus der Charité: Schottmann G, Lee CY, Morales-Gonzalez S, Schuelke M.
November 2019
Autoren:Middleton PG et al.
Titel:Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.
Zeitschrift (Journal):N Engl J Med. 2019 Nov 7;381(19):1809-1819. :Seiten (Pages):
Aus der Charité: Mall MA.Autoren:van der Heijde D et al.
Titel:Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial.
Zeitschrift (Journal):Lancet. 2019 Dec 7;394(10214):2108-2117. :Seiten (Pages):
Aus der Charité: Sieper J.Autoren:Ahmadi M et al.
Titel:A support programme for secondary prevention in patients with transient ischaemic attack and minor stroke (INSPiRE-TMS): an open-label, randomised controlled trial.
Zeitschrift (Journal):Lancet Neurol. 2019 Nov 7. doi: 10.1016/S1474-4422(19)30369-2. :Seiten (Pages):
Aus der Charité: Ahmadi M, Laumeier I, Ihl T, Steinicke M, Ferse C, Endres M, Schoene M, Kandil FI, Weber JE, Köhler F, Marx P, Audebert HJ.Autoren:Demichev V et al.
Titel:DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput.
Zeitschrift (Journal):Nat Methods. 2019 Nov 25. doi: 10.1038/s41592-019-0638-x. :Seiten (Pages):
Aus der Charité: Ralser M.Autoren:Sankowski R et al.
Titel:Mapping microglia states in the human brain through the integration of high-dimensional techniques.
Zeitschrift (Journal):Nat Neurosci. 2019 Dec;22(12):2098-2110. :Seiten (Pages):
Aus der Charité: Böttcher C, Priller J.Autoren:Primessnig U et al.
Titel:Long-term effects of Na+ /Ca2+ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Nov 24. doi: 10.1002/ejhf.1619. :Seiten (Pages):
Aus der Charité: Primessnig U, Pieske B, Heinzel FR.Autoren:Schewe J et al.
Titel:Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation.
Zeitschrift (Journal):Nat Commun. 2019 Nov 14;10(1):5155. :Seiten (Pages):
Aus der Charité: Schewe J, Seidel E, Forslund S, Marko L, Muller DN, Stölting G, Scholl U.Autoren:Qazi TH et al.
Titel:Niche-mimicking interactions in peptide-functionalized 3D hydrogels amplify mesenchymal stromal cell paracrine effects.
Zeitschrift (Journal):Biomaterials. 2019 Nov 20:119639. :Seiten (Pages):
Aus der Charité: Qazi TH, Duda GN, Geissler S.Autoren:Yildirim F et al.
Titel:Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington's disease.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2019 Dec3;116(49):24840-24851. :Seiten (Pages):
Aus der Charité: Yildirim F.Autoren:Brosig A et al.
Titel:The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches.
Zeitschrift (Journal):Cell Rep. 2019 Nov 12;29(7):2028-2040.e8. :Seiten (Pages):
Aus der Charité: Brosig A, Fuchs J, Ipek F, Kroon C, Schrötter S, Vadhvani M, Ledderose J, Holzhütter HG, Trimbuch T, Gimber N, Schmoranzer J, Rosenmund C, Spahn C, Scheerer P, Szczepek M, Eickholt BJ.
Oktober 2019
Autoren:Maurer M et al.
Titel:Ligelizumab for Chronic Spontaneous Urticaria.
Zeitschrift (Journal):N Engl J Med. 2019 Oct 3;381(14):1321-1332. :Seiten (Pages):
Aus der Charité: Maurer M, Metz M.Autoren:Patzke C et al.
Titel:Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses.
Zeitschrift (Journal):Cell. 2019 Oct 3;179(2):498-513.e22. :Seiten (Pages):
Aus der Charité: Brockmann MM, Grauel MK, Fenske P, Rosenmund C.Autoren:Eckert C et al.
Titel:Improving Stratification for Children With Late Bone Marrow B-Cell Acute Lymphoblastic Leukemia Relapses With Refined Response Classification and Integration of Genetics.
Zeitschrift (Journal):J Clin Oncol. 2019 Oct 23:JCO1901694. doi: 10.1200/JCO.19.01694. :Seiten (Pages):
Aus der Charité: Eckert C, Groeneveld-Krentz S, Kirschner-Schwabe R, Hagedorn N, Chen-Santel C, Astrahantseff K, Eggert A, Henze G, von Stackelberg A.Autoren:Wu H et al.
Titel:Lipid droplet-dependent fatty acid metabolism controls the immune suppressive phenotype of tumor-associated macrophages.
Zeitschrift (Journal):EMBO Mol Med. 2019 Nov 7;11(11):e10698. :Seiten (Pages):
Aus der Charité: Wu H, Rodriguez Sillke Y, Siddiqui S, Treese C, Schmidt F, Friedrich M, Keye J, Kühl AA, Siegmund B, Glauben R.Autoren:Strobel RM et al.
Titel:Reduction of Postoperative Wound Infections by Antiseptica (RECIPE)?: A Randomized Controlled Trial.
Zeitschrift (Journal):Ann Surg. 2019 Oct 9. doi: 10.1097/SLA.0000000000003645. :Seiten (Pages):
Aus der Charité: Strobel RM, Krochmann A, Neumann K, Speichinger F, Hartmann L, Lee LD, Beyer K, Daum S, Kreis ME, Lauscher JC.Autoren:Raccuglia D et al.
Titel:Network-Specific Synchronization of Electrical Slow-Wave Oscillations Regulates Sleep Drive in Drosophila.
Zeitschrift (Journal):Curr Biol. 2019 Nov 4;29(21):3611-3621.e3. :Seiten (Pages):
Aus der Charité: Raccuglia D, Ender A, Heim MM, Laber D, Suárez-Grimalt R, Liotta A, Sigrist SJ, Geiger JRP, Owald D.Autoren:Erdmann S et al.
Titel:CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer.
Zeitschrift (Journal):Theranostics. 2019 Sep 19;9(22):6719-6733. :Seiten (Pages):
Aus der Charité: Erdmann S, Niederstadt L, Koziolek EJ, Gómez JDC, Prasad S, Wagener A, von Hacht JL, Reinicke S, Exner S, Bandholtz S, Beindorff N, Brenner W, Grötzinger C.Autoren:Zidane M et al.
Titel:Decision-Analytic Modeling for Time-Effectiveness of the Sequence of Induction Treatments for Moderate to Severe Plaque Psoriasis.
Zeitschrift (Journal):JAMA Dermatol. 2019 Oct 16. doi: 10.1001/jamadermatol.2019.2941. :Seiten (Pages):
Aus der Charité: Zidane M, Dressler C, Gaskins M, Nast A.Autoren:Penack O et al.
Titel:Association of uric acid levels before start of conditioning with mortality after alloSCT: a prospective, non-interventional study of the EBMT Transplant Complication Working Party.
Zeitschrift (Journal):Haematologica. 2019 Oct 10. doi: 10.3324/haematol.2019.228668. :Seiten (Pages):
Aus der Charité: Penack O, Blau IW.Autoren:Arends CM et al.
Titel:Clonal hematopoiesis in patients with ANCA-associated vasculitis.
Zeitschrift (Journal):Haematologica. 2019 Oct 3. doi: 10.3324/haematol.2019.223305. :Seiten (Pages):
Aus der Charité: Arends CM, Weiss M, Christen F, Eulenberg-Gustavus C, Rousselle A, Kettritz R, Eckardt KU, Chan W, Hoyer K, Frick M, Bullinger L, Schreiber A, Damm F.
September 2019
Autoren:Nave AH et al.
Titel:Physical Fitness Training in Patients with Subacute Stroke (PHYS-STROKE): multicentre, randomised controlled, endpoint blinded trial.
Zeitschrift (Journal):BMJ. 2019 Sep 18;366:l5101. :Seiten (Pages):
Aus der Charité: Nave AH, Rackoll T, Grittner U, Audebert HJ, Klostermann F, Meisel A, Endres M, Ebinger M, Flöel A.Autoren:Pieske B et al.
Titel:How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).
Zeitschrift (Journal):Eur Heart J. 2019 Oct 21;40(40):3297-3317. :Seiten (Pages):
Aus der Charité: Pieske B, Tschöpe C, Anker SD, Edelmann F, Morris DA, Pieske-Kraigher E.Autoren:Wefers AK, et al.
Titel:Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.
Zeitschrift (Journal):Acta Neuropathol. 2019 Sep 28. doi: 10.1007/s00401-019-02078-w. :Seiten (Pages):
Aus der Charité: Capper D.Autoren:Jurmeister P et al.
Titel:Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases.
Zeitschrift (Journal):Sci Transl Med. 2019 Sep 11;11(509). :Seiten (Pages):
Aus der Charité: Jurmeister P, Bockmayr M, Bockmayr T, Treue D, Vollbrecht C, Arnold A, Teichmann D, Bressem K, von Laffert M, Capper D, Klauschen F.Autoren:Tschöpe C et al.
Titel:Immunosuppression in inflammatory cardiomyopathy and parvovirus B19 persistence.
Zeitschrift (Journal):Eur J Heart Fail. 2019 Sep 2. doi: 10.1002/ejhf.1560. :Seiten (Pages):
Aus der Charité: Tschöpe C, Elsanhoury A, Schlieker S, Van Linthout S, Kühl U.Autoren:Harnack C et al.
Titel:R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Zeitschrift (Journal):Nat Commun. 2019 Sep 25;10(1):4368. :Seiten (Pages):
Aus der Charité: Harnack C, Sigal M.Autoren:Kaminski J et al.
Titel:Association of Cortical Glutamate and Working Memory Activation in Patients With Schizophrenia: A Multimodal Proton Magnetic Resonance Spectroscopy and Functional Magnetic Resonance Imaging Study. Biol Psychiatry. 2019 Jul 26. doi: 10.1016/j.biopsych.2019.07.011.
Zeitschrift (Journal):Biol Psychiatry. 2019 Jul 26. doi: 10.1016/j.biopsych.2019.07.011. :Seiten (Pages):
Aus der Charité: Kaminski J, Gleich T, Fukuda Y, Katthagen T, Heinz A, Schlagenhauf F.Autoren:Zimmermann C et al.
Titel:Mast cells are critical for controlling the bacterial burden and the healing of infected wounds.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20500-20504. :Seiten (Pages):
Aus der Charité: Zimmermann C, Troeltzsch D, Giménez-Rivera VA, Metz M, Maurer M, Siebenhaar F.Autoren:Pfuhl C et al.
Titel:Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis.
Zeitschrift (Journal):Neurology. 2019 Oct 8;93(15):e1439-e1451. :Seiten (Pages):
Aus der Charité: Pfuhl C, Grittner U, Gieß RM, Scheel M, Behrens JR, Rasche L, Pache FC, Wenzel R, Brandt AU, Bellmann-Strobl J, Paul F, Ruprecht K.Autoren:Shahryari M et al.
Titel:Tomoelastography distinguishes non-invasively between benign and malignant liver lesions.
Zeitschrift (Journal):Cancer Res. 2019 Sep 24. doi: 10.1158/0008-5472.CAN-19-2150. :Seiten (Pages):
Aus der Charité: Shahryari M, Tzschätzsch H, Guo J, Marticorena Garcia SR, Böning G, Fehrenbach U, Stencel L, Asbach P, Hamm B, Braun J, Sack I.
August 2019
Autoren:Olin-Sandoval V et al.
Titel:Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism.
Zeitschrift (Journal):Nature. 2019 Aug;572(7768):249-253. :Seiten (Pages):
Aus der Charité: Mülleder M, Ralser M.Autoren:Brandt L et al.
Titel:Risk of Psychosis Among Refugees: A Systematic Review and Meta-analysis.
Zeitschrift (Journal):JAMA Psychiatry. 2019 Aug 14. doi: 10.1001/jamapsychiatry.2019.1937. :Seiten (Pages):
Aus der Charité: Brandt L, Henssler J, Wall S, Gabel D, Heinz A.Autoren:Masuda T et al.
Titel:Association With Hospitalization and All-Cause Discontinuation Among Patients With Schizophrenia on Clozapine vs Other Oral Second-Generation Antipsychotics: A Systematic Review and Meta-analysis of Cohort Studies.
Zeitschrift (Journal):JAMA Psychiatry. 2019 Jul 31. doi: 10.1001/jamapsychiatry.2019.1702. :Seiten (Pages):
Aus der Charité: Correll CU.Autoren:Dölle-Bierke S et al.
Titel:Detection of KIT D816V mutation in patients with severe anaphylaxis and normal basal tryptase-first data from the Anaphylaxis Registry (NORA).
Zeitschrift (Journal):J Allergy Clin Immunol. 2019 Aug 12. doi: 10.1016/j.jaci.2019.07.037. :Seiten (Pages):
Aus der Charité: Dölle-Bierke S, Siebenhaar F, Burmeister T, Worm M.Autoren:Kuhlmann SL et al.
Titel:Prevalence, 12-Month Prognosis, and Clinical Management Need of Depression in Coronary Heart Disease Patients: A Prospective Cohort Study.
Zeitschrift (Journal):Psychother Psychosom. 2019 Aug 26:1-12. doi: 10.1159/000501502. :Seiten (Pages):
Aus der Charité: Kuhlmann SL, Haverkamp W, Ströhle A, Rieckmann N, Müller-Nordhorn J.Autoren:Tzilivaki A et al.
Titel:Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators.
Zeitschrift (Journal):Nat Commun. 2019 Aug 14;10(1):3664. :Seiten (Pages):
Aus der Charité: Tzilivaki A.Autoren:Horn A et al.
Titel:Deep brain stimulation induced normalization of the human functional connectome in Parkinson's disease.
Zeitschrift (Journal):Brain. 2019 Aug 14. doi: 10.1093/brain/awz239. :Seiten (Pages):
Aus der Charité: Horn A, Wenzel G, Irmen F, Huebl J, Li N, Neumann WJ, Krause P, Bohner G, Scheel M, Kühn AA.Autoren:Al-Fatly B et al.
Titel:Connectivity profile of thalamic deep brain stimulation to effectively treat essential tremor.
Zeitschrift (Journal):Brain. 2019 Aug 3. doi: 10.1093/brain/awz236. :Seiten (Pages):
Aus der Charité: Al-Fatly B, Ewert S, Kübler D, Kroneberg D, Horn A, Kühn AA.Autoren:Hahn A et al.
Titel:Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Zeitschrift (Journal):J Cachexia Sarcopenia Muscle. 2019 Aug 23. doi: 10.1002/jcsm.12491. :Seiten (Pages):
Aus der Charité: Hahn A, Kny M, Pablo-Tortola C, Schmidt S, Nowak M, Weber-Carstens S, Luft FC, Fielitz J.Autoren:Rasche A et al.
Titel:Highly diversified shrew hepatitis B viruses corroborate ancient origins and divergent infection patterns of mammalian hepadnaviruses.
Zeitschrift (Journal):Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):17007-17012. :Seiten (Pages):
Aus der Charité: Rasche A, Corman VM, Moreira-Soto A, Sander AL, Drosten C, Drexler JF.
Juli 2019
Autoren:Despang A et al.
Titel:Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture.
Zeitschrift (Journal):Nat Genet. 2019 Aug;51(8):1263-1271. :Seiten (Pages):
Aus der Charité: Despang A, Schöpflin R, Ali S, Jerković I, Paliou C, Chan WL, Mundlos S, Ibrahim DM.Autoren:Mattiola I et al.
Titel:The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis.
Zeitschrift (Journal):Nat Immunol. 2019 Aug;20(8):1012-1022. :Seiten (Pages):
Aus der Charité: Mattiola I.Autoren:Brandt R et al.
Titel:Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium.
Zeitschrift (Journal):Nat Commun. 2019 Jul 2;10(1):2919. :Seiten (Pages):
Aus der Charité: Brandt R, Sell T, Lüthen M, Uhlitz F, Klinger B, Riemer P, Schulze S, El-Shimy IA, Kunkel D, Herrmann BG, Sers C, Blüthgen N, Morkel M.Autoren:Lueckgen A et al.
Titel:Enzymatically-degradable alginate hydrogels promote cell spreading and in vivo tissue infiltration.
Zeitschrift (Journal):Biomaterials. 2019 Oct;217:119294. :Seiten (Pages):
Aus der Charité: Lueckgen A, Garske DS, Ellinghaus A, Duda GN, Cipitria A.Autoren:Fischer-Zirnsak B et al.
Titel:Haploinsufficiency of the Notch Ligand DLL1 Causes Variable Neurodevelopmental Disorders.
Zeitschrift (Journal):Am J Hum Genet. 2019 Jul 19. doi: 10.1016/j.ajhg.2019.07.002 :Seiten (Pages):
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Juni 2019
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Titel:PEDIA: prioritization of exome data by image analysis.
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Titel:Mutational Diversity and Therapy Response in Breast Cancer: A Sequencing Analysis in the Neoadjuvant GeparSepto Trial.
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Titel:Confirmation of the prognostic value of pretherapeutic tumor SUR and MTV in patients with esophageal squamous cell carcinoma.
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Titel:2018 EULAR recommendations for a core data set to support observational research and clinical care in giant cell arteritis.
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