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Dr. Jan Saam
Theoretical and Computational Biophysics Group
phone +1 217-244-1928 |
Research Interests
Education and Training
- 1996-1998 studied biology (Grundstudium) at University of Konstanz, Germany.
- 1998-2001 studied biophysics (Hauptstudium) at Humboldt University Berlin, Germany.
- May 2001-April 2002 visiting scholar at the Theoretical and Computational Biophysics Group, University of Illinois.
- Oct. 2002 - Nov 2007 PhD studies in biophysics at Charité Campus Mitte, Berlin.
Publications
Saam J, Ivanov I, Walther M, Holzhütter H, and Kuhn H. (2007) Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channels. Proc. Natl. Acad. Sci., 104(33), 13319-13324 [PubMed]
Ivanov I, Saam J, Kühn H, Holzhütter H. (2005)
Dual role of oxygen during lipoxygenase reactions.
FEBS Journal 272, 2523-2535 [pdf]
Kühn, H, Saam J, Eibach S, Holzhütter H, Ivanov I, Walther M. (2005)
Structural biology of mammalian lipoxygenases: Enzymatic
consequences of targeted alterations of the protein structure
Biochem. Biophys. Res. Commun. 338, 93-101 [pdf]
Saam J, Tajkhorshid E, Hayashi S, and Schulten K. (2002)
Molecular Dynamics Investigation of Primary Photoinduced Events in the Activation of Rhodopsin.
Biophys. J. 83, 3097-3112 [pdf,
PubMed]
Ernsting NP, Kovalenko SA, Senyushkina T, Saam J and Farztdinov V. (2001)
Wave-packet-assisted decomposition of femtosecond transient ultraviolet-visible absorption spectra: Application to excited-state intramolecular proton
transfer in solution.
J. Phys. Chem. A 105, 3443-3453
[journal]
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