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Dr. Kristian Rother
Structural Bioinformatics Laboratory krother |
genesilico.pl
Research Interests
- Columba - Data integration on protein structures
- Systematic classification of metabolic reactions
- Packing analysis of protein structures
- PyMOL - Molecular Visualization
Academic degrees and positions
- 7/2002 - 2/2006 Graduate student at the Protein Structure Theory Group/Prof. C. Frömmel, Charité - Universitätsmedizin Berlin
- 10/1996 - 3/2002 Diploma of Biochemistry at the Freie Universität Berlin. Diploma thesis: Packungsdichte und Packungsdefekte in Proteinstrukturen
- 06/1996 Abitur at the 8.OG (Gymnasium Steglitz) Berlin
Publications
Gille C, Bölling C, Hoppe A, Bulik S, Hoffmann S, Hübner K, Karlstädt A, Ganeshan R, König M, Rother K, Weidlich M, Behre J, Holzhütter HG. (2010) HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology. Mol Syst Biol., 6:411. [PubMed]
Rother K, Hoffmann S, Bulik S, Hoppe A, Gasteiger J, Holzhütter HG. (2010) IGERS: Inferring Gibbs energy changes of biochemical reactions from reaction similarities. Biophys J., 98(11):2478-86. [PubMed]
Günther S, Rother K, Frömmel C.
Molecular flexibility in protein-DNA interactions. Biosystems. 2006 Feb 16; [Epub ahead of print].
Rother K, Dunkel M, Michalsky E, Trissl S, Goede A, Leser U, Preißner R.
A structural keystone for drug design. Journal of Integrative Bioinformatics. 2006 Jan 19;0019. Online Journal.
Rother K, Michalsky E, Leser U.
How well are protein structures annotated in secondary databases? Proteins. 2005 Sep 1;60(4):571-576.
Trissl S, Rother K, Müller H, Steinke T, Koch I, Preißner R, Frömmel C, Leser U.
Columba: an integrated database of proteins, structures, and annotations. BMC Bioinformatics. 2005 Mar 31;6(1):81.
Hildebrand PW, Rother K, Goede A, Preißner R, Frömmel C.
Molecular packing and packing defects in helical membrane proteins. Biophys J. 2005 Mar;88(3):1970-1977.
Rother K, Müller H, Trissl S, Koch I, Steinke T, Preißner R, Frömmel C, Leser, U.
Columba: Multidimensional Data Integration of Protein Annotations. Lecture Notes in Computer Science, 2994 , 156-171. Springer, 2004.
Rother K, Preißner R, Goede A, Frömmel C.
Inhomogeneous molecular density: reference packing densities and distribution of cavities within proteins.
Bioinformatics. 2003 Nov 1;19(16):2112-2121.
Preißner R, Goede A, Rother K, Osterkamp F, Koert U, Frömmel C.
Matching organic libraries with protein-substructures. J Comput Aided Mol Des. 2001 Sep;15(9):811-817.
Gille C, Goede A, Preißner R, Rother K, Frömmel C.
Conservation of substructures in proteins: interfaces of secondary structural elements in proteasomal subunits. J Mol Biol. 2000 Jun 16;299(4):1147-1154.
Exhibitions
- Proteinstrukturkalligraphie, Lise-Meitner-Hörsaal, FU Berlin (2006)
- Missing Link: Art Meets Biomedicine, The Rubelle & Norman Schafler Gallery, Brookly, N.Y. (2006)
- arts & science in vitro - Der seltsame Tanz der sozialen Amöbe, public act at the Institute of Biochemistry, Charite Berlin (2006)
- Missing Link - Communication in Arts and Science, BMM Charite Berlin (2005)