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Dr. Carola Huthmacher
Computational Systems Biochemistry Group
carola.huthmacher |
charite.de
Research Interests
- Functional Relevance of Protein-Protein Interactions in Metabolic Networks
Education and Training
- Oct 2000 - July 2006: Studies in Bioinformatics at Eberhard-Karls University (Tübingen, Germany)
- Sep 2003 - June 2004: Studies in Computer Science & Biology at Oregon State University (Corvallis, OR, USA)
- Aug 2005 - April 2006: Diploma thesis at Max-Planck-Institute for Informatics (Saarbrücken, Germany)
- Sep 2006 - June 2010: PhD student in the Computational Systems Biochemistry Group at the Charité (Berlin, Germany)
Publications
Huthmacher C, Hoppe A, Bulik S, Holzhutter HG. (2010) Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. BMC Syst Biol., 4(1):120. [Epub ahead of print] [PubMed]
Bulik S, Grimbs S, Huthmacher C, Selbig J, Holzhütter HG. (2009) Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws: A promising method for speeding up the kinetic modelling of complex metabolic networks. FEBS Journal, 276:410-424 [PubMed]
Huthmacher C, Gille C, Holzhütter HG. (2008) A computational analysis of protein interactions in metabolic networks reveals novel enzyme pairs potentially involved in metabolic channeling. J Theor Biol., 252(3):456-64. [PubMed]
Huthmacher C, Gille C, Holzhütter HG. (2007) Computational analysis of protein-protein interactions in metabolic networks of Escherichia coli and yeast. Genome Inform., 18:162-72. [PubMed]
Schlicker A, Huthmacher C, Ramírez F, Lengauer T, Albrecht M. (2007) Functional evaluation of domain-domain interactions and human protein interaction networks. Bioinformatics., 23(7):859-65. [PubMed]
Albrecht M, Huthmacher C, Tosatto SC, Lengauer T. (2005) Decomposing protein networks into domain-domain interactions. Bioinformatics., 21 Suppl 2:ii220-1. [PubMed]