|
Dr. Bernd Binder
Computational Systems Biochemistry Group
phone +49 30 450528-197 |
charite.de
Research Interests
- Investigation of the design properties of signal transduction networks. Methods: system theory, graph theory, evolutionary algorithms.
- Mathematical modeling of the vesicle transport
Education and Training
- Diploma thesis in nuclear physics at Max-Planck-Institut for Nuclear Physics, Heidelberg
- Analysis of gene expressing data at German Cancer Research Center, Heidelberg
- PhD in theoretical Biophysics at Humboldt-University Berlin (supervisor: Reinhart Heinrich)
Publications
Binder B, Goede A, Berndt N, Holzhütter HG. (2009) A conceptual mathematical model of the dynamic self-organisation of distinct cellular organelles. PLoS One, 4(12):e8295. [PubMed]
Binder B, Ebenhöh O, Hashimoto K, Heinrich R. (2006)
Expansion of signal transduction networks.
Syst Biol (Stevenage), 153(5):364-8.
[PubMed]
Binder B, Heinrich R. (2005)
Structural and dynamical analyses of the kinase network derived from the transpath database.
Genome Inform., 16(1):164-73.
[PubMed]
Hornberg JJ, Binder B, Bruggeman FJ, Schoeberl B, Heinrich R, Westerhoff HV. (2005)
Control of MAPK signalling: from complexity to what really matters.
Oncogene., 24(36):5533-42.
[PubMed]
Hornberg JJ, Bruggeman FJ, Binder B, Geest CR, de Vaate AJ, Lankelma J, Heinrich R, Westerhoff HV. (2005)
Principles behind the multifarious control of signal transduction. ERK phosphorylation and kinase/phosphatase control.
FEBS J., 272(1):244-58.
[PubMed]
Binder, B. (2005).
Design principles and control mechanisms of signal transduction networks. PhD thesis, Humboldt University Berlin.
[pdf]
Binder B, Heinrich R. (2004)
Interrelations between dynamical properties and structural characteristics of signal transduction networks.
Genome Inform., 15(1):13-23.
[PubMed]
Binder B, Heinrich R. (2002)
Dynamic stability of signal transduction networks depending on downstream and upstream specificity of protein kinases.
Molecular biology reports, 29, 51-55.
[Abstract]