Recent publications from SFB 665 projects


A2


Wulczyn FG, Cuevas E, Franzoni E, Rybak A. miRNAs Need a Trim : Regulation of miRNA Activity by Trim-NHL Proteins. Adv Exp Med Biol. 2011;700:85-105.
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A4


Scharff C, Petri J. Evo-devo, deep homology and FoxP2: implications for the evolution of speech and language. Philos Trans R Soc Lond B Biol Sci. 2011 Jul 27;366(1574):2124-40.
Abstract


Tokarev K, Tiunova A, Scharff C, Anokhin K. Food for song: expression of c-Fos and ZENK in the zebra finch song nuclei during food aversion learning. PLoS One. 2011;6(6):e21157.
Abstract


Schulz SB, Haesler S, Scharff C, Rochefort C. Knockdown of FoxP2 alters spine density in Area X of the zebra finch. Genes Brain Behav. 2010 Jun 2.
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A7


Braun D, Kim TD, le Coutre P, Köhrle J, Hershman JM, Schweizer U. Tyrosine Kinase Inhibitors Noncompetitively Inhibit MCT8-Mediated Iodothyronine Transport. J Clin Endocrinol Metab. 2011 Oct 26.
Abstract


Wirth EK, Sheu SY, Chiu-Ugalde J, Sapin R, Klein MO, Mossbrugger I, Quintanilla-Martinez L, de Angelis MH, Krude H, Riebel T, Rothe K, Köhrle J, Schmid KW, Schweizer U, Grüters A. Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy. Eur J Endocrinol. 2011 Oct;165(4):555-61.
Abstract


Braun D, Wirth EK, Schweizer U. Thyroid hormone transporters in the brain. Rev Neurosci. 2010;21(3):173-86.
Abstract


Kinne A, Kleinau G, Hoefig CS, Grüters A, Köhrle J, Krause G, Schweizer U. Essential molecular determinants for thyroid hormone transport and first structural implications for monocarboxylate transporter 8. J Biol Chem. 2010 Sep 3;285(36):28054-63.
Abstract


Roth S, Kinne A, Schweizer U. The tricyclic antidepressant desipramine inhibits T3 import into primary neurons. Neurosci Lett. 2010 Jun 30;478(1):5-8. Epub 2010 May 6.
Abstract


A8


Christ A, Christa A, Kur E, Lioubinski O, Bachmann S, Willnow TE, Hammes A. LRP2 Is an Auxiliary SHH Receptor Required to Condition the Forebrain Ventral Midline for Inductive Signals. Dev Cell. 2012 Feb 14;22(2):268-78.
Abstract


Kur E, Christa A, Veth KN, Gajera CR, Andrade-Navarro MA, Zhang J, Willer JR, Gregg RG, Abdelilah-Seyfried S, Bachmann S, Link BA, Hammes A, Willnow TE. Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development. Dev Dyn. 2011 Mar 31.
Abstract


Christ A, Terryn S, Schmidt V, Christensen EI, Huska MR, Andrade-Navarro MA, Hübner N, Devuyst O, Hammes A, Willnow TE. The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo. Kidney Int. 2010 Sep;78(5):473-7.
Abstract


Gajera CR, Emich H, Lioubinski O, Christ A, Beckervordersandforth-Bonk R, Yoshikawa K, Bachmann S, Christensen EI, Götz M, Kempermann G, Peterson AS, Willnow TE, Hammes A. LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche. J Cell Sci. 2010 Jun 1;123(Pt 11):1922-30.
Abstract


A9


Czeh M, Gressens P, Kaindl AM. The yin and yang of microglia. Dev Neurosci. 2011;33(3-4):199-209.
Abstract


Kraemer N, Issa L, Hauck SC, Mani S, Ninnemann O, Kaindl AM. What's the hype about CDK5RAP2? Cell Mol Life Sci. 2011 May;68(10):1719-36.
Abstract


Ikonomidou C, Kaindl AM. Neuronal death and oxidative stress in the developing brain. Antioxid Redox Signal. 2010 Oct 4.
Abstract


A10


Boppana S, Scheglov A, Geffers R, Tarabykin V. Cellular retinaldehyde-binding protein (CRALBP) is a direct downstream target of transcription factor Pax6. Biochim Biophys Acta. 2011 Oct 4.
Abstract


Yamagishi S, Hampel F, Hata K, Del Toro D, Schwark M, Kvachnina E, Bastmeyer M, Yamashita T, Tarabykin V, Klein R, Egea J. FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons. EMBO J. 2011 Jun 14;30(14):2920-33.
Abstract


Karalay O, Doberauer K, Vadodaria KC, Knobloch M, Berti L, Miquelajauregui A, Schwark M, Jagasia R, Taketo MM, Tarabykin V, Lie DC, Jessberger S. Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5807-12.
Abstract


Moldrich RX, Gobius I, Pollak T, Zhang J, Ren T, Brown L, Mori S, De Juan Romero C, Britanova O, Tarabykin V, Richards LJ. Molecular regulation of the developing commissural plate. J Comp Neurol. 2010 Sep 15;518(18):3645-61.
Abstract


B1


Wende H, Lechner SG, Cheret C, Bourane S, Kolanczyk ME, Pattyn A, Reuter K, Munier FL, Carroll P, Lewin GR, Birchmeier C.The transcription factor c-Maf controls touch receptor development and function. Science. 2012 Mar 16;335(6074):1373-6. (with Project B6)
Abstract


Fricker FR, Lago N, Balarajah S, Tsantoulas C, Tanna S, Zhu N, Fageiry SK, Jenkins M, Garratt AN, Birchmeier C, Bennett DL. Axonally derived Neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood. J Neurosci. 2011 Mar 2;31(9):3225-33.
Abstract


Newbern J, Birchmeier C. Nrg1/ErbB signaling networks in Schwann cell development and myelination. Semin Cell Dev Biol. 2010 Sep 9.
Abstract


B2


Schmidt H, Rathjen FG. DiI-labeling of DRG neurons to study axonal branching in a whole mount preparation of mouse embryonic spinal cord. J Vis Exp. 2011 Dec 13;(58).
Abstract


Schmidt H, Rathjen FG. Signalling mechanisms regulating axonal branching in vivo. Bioessays. 2010 Sep 8.
Abstract


B5


Ibañez-Tallon I, Nitabach MN. Tethering toxins and peptide ligands for modulation of neuronal function. Curr Opin Neurobiol. 2011 Nov 24.
Abstract


Santos-Torres J, Limak MA, Auer S, Ibañez-Tallon I. Cross-reactivity of acid-sensing ion channel and Na+-H+ exchanger antagonists with nicotinic acetylcholine receptors. J Physiol. 2011 Nov 1;589(Pt 21):5109-23.
Abstract


Frahm S, Slimak MA, Ferrarese L, Santos-Torres J, Antolin-Fontes B, Auer S, Filkin S, Pons S, Fontaine JF, Tsetlin V, Maskos U, Ibañez-Tallon I.Aversion to Nicotine Is Regulated by the Balanced Activity of β4 and α5 Nicotinic Receptor Subunits in the Medial Habenula. Neuron. 2011 May 12;70(3):522-35.
Abstract


Lechner SG, Markworth S, Poole K, Smith ES, Lapatsina L, Frahm S, May M, Pischke S, Suzuki M, Ibañez-Tallon I, Luft FC, Jordan J, Lewin GR. The molecular and cellular identity of peripheral osmoreceptors. Neuron. 2011 Jan 27;69(2):332-44. (with Project B6)
Abstract


Auer S, Ibañez-Tallon I. "The King is dead": Checkmating ion channels with tethered toxins. Toxicon. 2010 Oct 7.
Abstract


B6


Smith ES, Omerbašić D, Lechner SG, Anirudhan G, Lapatsina L, Lewin GR.The molecular basis of acid insensitivity in the African naked mole-rat.Science. 2011 Dec 16;334(6062):1557-60.
Abstract


Wende H, Lechner SG, Cheret C, Bourane S, Kolanczyk ME, Pattyn A, Reuter K, Munier FL, Carroll P, Lewin GR, Birchmeier C.The transcription factor c-Maf controls touch receptor development and function. Science. 2012 Mar 16;335(6074):1373-6. (with Project B1)
Abstract


Heidenreich M, Lechner SG, Vardanyan V, Wetzel C, Cremers CW, De Leenheer EM, Aránguez G, Moreno-Pelayo MA, Jentsch TJ, Lewin GR. KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man. Nat Neurosci. 2011 Nov 20.
Abstract


Tappe-Theodor A, Constantin CE, Tegeder I, Lechner SG, Langeslag M, Lepcynzsky P, Wirotanseng RI, Kurejova M, Agarwal N, Nagy G, Todd A, Wettschureck N, Offermanns S, Kress M, Lewin GR, Kuner R. Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization. Pain. 2011 Nov 7.
Abstract


Stürzebecher AS, Hu J, Smith ES, Frahm S, Santos-Torres J, Kampfrath B, Auer S, Lewin GR, Ibañez-Tallon I. An in vivo tethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors. J Physiol. 2010 May 15;588(Pt 10):1695-707. (with Project B5)
Abstract


Lechner SG, Markworth S, Poole K, Smith ES, Lapatsina L, Frahm S, May M, Pischke S, Suzuki M, Ibañez-Tallon I, Luft FC, Jordan J, Lewin GR. The molecular and cellular identity of peripheral osmoreceptors. Neuron. 2011 Jan 27;69(2):332-44. (with Project B5)
Abstract


B8


Maier N, Tejero-Cantero A, Dorrn AL, Winterer J, Beed PS, Morris G, Kempter R, Poulet JF, Leibold C, Schmitz D. Coherent phasic excitation during hippocampal ripples. Neuron. 2011 Oct 6;72(1):137-52.
Abstract


Schuchmann S, Hauck S, Henning S, Grüters-Kieslich A, Vanhatalo S, Schmitz D, Kaila K. Respiratory alkalosis in children with febrile seizures. Epilepsia. 2011 Nov;52(11):1949-55.
Abstract


Wiegand HF, Beed P, Bendels MH, Leibold C, Schmitz D, Johenning FW. Complementary sensory and associative microcircuitry in primary olfactory cortex. J Neurosci. 2011 Aug 24;31(34):12149-58.
Abstract


Beed P, Bendels MH, Wiegand HF, Leibold C, Johenning FW, Schmitz D. Analysis of excitatory microcircuitry in the medial entorhinal cortex reveals cell-type-specific differences. Neuron. 2010 Dec 22;68(6):1059-66.
Abstract


Rost BR, Breustedt J, Schoenherr A, Grosse G, Ahnert-Hilger G, Schmitz D. Autaptic cultures of single hippocampal granule cells of mice and rats. Eur J Neurosci. 2010 Sep;32(6):939-47.
Abstract


Maier N, Morris G, Schuchmann S, Korotkova T, Ponomarenko A, Böhm C, Wozny C, Schmitz D. Cannabinoids disrupt hippocampal sharp wave-ripples via inhibition of glutamate release. Hippocampus. 2011 Aug 18.
Abstract


Rost BR, Nicholson P, Ahnert-Hilger G, Rummel A, Rosenmund C, Breustedt J, Schmitz D. Activation of metabotropic GABA receptors increases the energy barrier for vesicle fusion. J Cell Sci. 2011 Sep 15;124(Pt 18):3066-73. (with Project B11)
Abstract


Bähner F, Weiss EK, Birke G, Maier N, Schmitz D, Rudolph U, Frotscher M, Traub RD, Both M, Draguhn A. Cellular correlate of assembly formation in oscillating hippocampal networks in vitro. Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):E607-16.
Abstract


Winterer J, Stempel AV, Dugladze T, Földy C, Maziashvili N, Zivkovic AR, Priller J, Soltesz I, Gloveli T, Schmitz D. Cell-type-specific modulation of feedback inhibition by serotonin in the hippocampus. J Neurosci. 2011 Jun 8;31(23):8464-75.
Abstract


B9


Banovic D, Khorramshahi O, Owald D, Wichmann C, Riedt T, Fouquet W, Tian R, Sigrist SJ, Aberle H. Drosophila neuroligin 1 promotes growth and postsynaptic differentiation at glutamatergic neuromuscular junctions. Neuron. 2010 Jun 10;66(5):724-38.
Abstract


B10


Munz M, Brecht M, Wolfe J. Active touch during shrew prey capture. Front Behav Neurosci. 2010 Dec 29;4:191.
Abstract


C4


Knierim E, Lucke B, Schwarz JM, Schuelke M, Seelow D. Systematic comparison of three methods for fragmentation of long-range PCR products for next generation sequencing. PLoS One. 2011;6(11):e28240. Epub 2011 Nov 30.
Abstract


Logan CV, Lucke B, Pottinger C, Abdelhamed ZA, Parry DA, Szymanska K, Diggle CP, Riesen A, Morgan JE, Markham G, Ellis I, Manzur AY, Markham AF, Shires M, Helliwell T, Scoto M, Hübner C, Bonthron DT, Taylor GR, Sheridan E, Muntoni F, Carr IM, Schuelke M, Johnson CA. Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD). Nat Genet. 2011 Nov 20;43(12):1189-92.
Abstract


Wirtz S and Schuelke M. Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development. PLoS One. 2011 Apr 27;6(4):e18897.
Abstract


Knierim E, Leisle L, Wagner C, Weschke B, Lucke B, Bohner G, Dreier JP, Schuelke M. Recurrent stroke due to a novel voltage sensor mutation in Cav2.1 responds to verapamil. Stroke. 2011 Feb;42(2):e14-7.
Abstract


Kann O, Huchzermeyer C, Kovács R, Wirtz S, Schuelke M. Gamma oscillations in the hippocampus require high complex I gene expression and strong functional performance of mitochondria. Brain. 2011 Feb;134(Pt 2):345-58.
Abstract


Brinckmann A, Weiss C, Wilbert F, von Moers A, Zwirner A, Stoltenburg-Didinger G, Wilichowski E, Schuelke M. Regionalized Pathology Correlates with Augmentation of mtDNA Copy Numbers in a Patient with Myoclonic Epilepsy with Ragged-Red Fibers (MERRF-Syndrome). PLoS One. 2010 Oct 20;5(10):e13513.
Abstract


Krawitz PM, Schweiger MR, Rödelsperger C, Marcelis C, Kölsch U, Meisel C, Stephani F, Kinoshita T, Murakami Y, Bauer S, Isau M, Fischer A, Dahl A, Kerick M, Hecht J, Köhler S, Jäger M, Grünhagen J, de Condor BJ, Doelken S, Brunner HG, Meinecke P, Passarge E, Thompson MD, Cole DE, Horn D, Roscioli T, Mundlos S, Robinson PN. Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome. Nat Genet. 2010 Oct;42(10):827-9.
Abstract


Schwarz JM, Rödelsperger C, Schuelke M, Seelow D. MutationTaster evaluates disease-causing potential of sequence alterations. Nat Methods. 2010 Aug;7(8):575-6.
Abstract


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