Project (code) |
Title |
Research area |
Principal investigator, institute, location |
Project Area A: Innate immunity - attack and defense |
|||
| The role of innate immune receptors in neurodegeneration | Neurology, Immunology |
Seija Lehnardt Department of Neurology, Berlin |
|
| Role of inflammation for long-term post-stroke outcome | Neurology, Brain Ischemia, Stroke |
Matthias Endres Department of Neurology, Berlin Ulrich Dirnagl Experimental Neurology, Berlin |
|
| Control of microglial function by activation of neurotransmitter and neurohormone receptors | Neuroscience | Helmut Kettenmann, Susanne Wolf MDC for Molecular Medicine, Berlin |
|
| Phenotypic diversity of microglia | Neurobiology, Neuroimmunology, Glia | Uwe-Karsten Hanisch Department of Neuropathology, Göttingen |
|
| Dissecting mechanisms of immune actions in Alzheimer’s disease | Neuroimmunology, Neurodegeneration, Experimental Neuropathology, Transgenic murine mice models | Frank Heppner Department of Neuropathology, Berlin |
|
| Differential roles of resident microglia and myeloid cells in neuroinflammatory conditions | Neurology, Psychiatry, Neuroimmunology | Josef Priller Department of Neuropsychiatry, Berlin |
|
| Activation of the Inflammasome in Amyotrophic Lateral Sclerosis | Neuroimmunology, Neuropathology |
Arturo Zychlinsky MPI for Infection Biology, Berlin |
|
| Connecting myelin membrane turnover with antigen presenting cells and autoimmunity | Neurology, Cell Biology, Neurobiology |
Mikael Simons Department of Neurology, MPI for Experimental Medicine, Göttingen |
|
Project Area B: Adaptive immunity - trafficking and damage |
|||
| Role of CNS antigen-specific T cell responses for regeration and functional outcome after stroke and impact of post-stroke infections | Neurology, Stroke, Immunology |
Andreas Meisel Department of Neurology, Berlin Christian Meisel Institute of Medical Immunology, Berlin |
|
| Secondary neuroinflammation in the CNS white matter and its modulation by erythropoietin | Molecular and Cellular Neurobiology, Mouse models of disease | Klaus-Armin Nave Department of Neurogenetics, MPI of experimental Medicine, Göttingen |
|
| The role of immunoproteasomes and the ubiquitin system in inflammatory processes in mouse models of Alzheimer's and Parkinson's disease | Neuroimmunology, Neurology | Peter-Michael Kloetzel, Elke Krüger Institute of Biochemistry, Berlin Frank Heppner Department of Neuropathology, Berlin |
|
| Axonal and neuronal damage as pathological substrates of disease progression in MS | Neuropathology, Neuroimmunology | Christine Stadelmann-Nessler, Wolfgang Brück Department of Neuropathology, Göttingen |
|
| Encephalitogenic T cells during preclinical EAE: migratory behavior and functional analysis of fluorescent GFP-transduced T cells | Neuroimmunology | Francesca Odoardi Institute for MS Research, Göttingen Alexander Flügel Department of Neuroimmunology, Göttingen |
|
| Intravital analyses of T cell priming and effector phases during active and spontaneous EAE | Neuroimmunology | Alexander Flügel Department of Neuroimmunology, Göttingen Fred Lühder Institute for MS Research, Göttingen |
|
| Cerebral Spreading Inflammation (CSI) after Acute Subarachnoid Hemorrhage (aSAH) - An Intraparenchymal Reaction to an Extraparenchymal Disease | Neurosurgery, Microcirculation | Peter Vajkoczy Department of Neurosurgery, Berlin |
|
| Role of CD8+ T cells in neuroinflammation and damage in a rat model of RRMS | Immunology | Holger Reichardt Department of Cellular and Molecular Immunology, Göttingen |
|
Project Area C: Core project | Integrated Research Training Group |
|||
C1
|
Administrative office of the SFB TRR43 | Frank Heppner Department of Neuropathology, Berlin |
|
MGK
|
Integrated Research Training Group "The Brain as a Target of Inflammatory Processes" | Helmut Kettenmann Max Delbrück Center for Molecular Medicine (MDC), Berlin Uwe-Karsten Hanisch Department of Neuropathology, Göttingen |
|