The Schmitzlab
at the Neuroscience Research Center (NWFZ)  -  Charité Berlin

 
     
 

Selected Publications

  • Vogt J, Glumm R, Schlüter L, Schmitz D, Rost BR, Streu N, Rister B, Suman Bharathi B, Gagiannis D, Hildebrandt H, Weinhold B, Mühlenhoff M, Naumann T, Savaskan NE, Brauer AU, Reutter W, Heimrich B, Nitsch R, Horstkorte R. (2011) Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting.
    Proc Cell Mol Life Sci. 2011 Nov 09.

  • Maier N, Tejero-Cantero A, Dorrn AL, Winterer J, Beed PS, Morris G, Kempter R, Poulet JF, Leibold C, Schmitz D.(2011) Coherent phasic excitation during hippocampal ripples.
    Neuron. 2011 Oct 6;72(1):137-52

  • Schuchmann S, Hauck S, Henning S, Grüters-Kieslich A, Vanhatalo S, Schmitz D, Kaila K.(2011) Respiratory alkalosis in children with febrile seizures.
    Epilepsia. 2011 Nov;52(11):1949-1955.

  • Maier N, Morris G, Schuchmann S, Korotkova T, Ponomarenko A, Böhm C, Wozny C, Schmitz D.(2011) Cannabinoids disrupt hippocampal sharp wave-ripples via inhibition of glutamate release.
    Hippocampus. 2011 Aug 18

  • Wiegand HF, Beed P, Bendels MH, Leibold C, Schmitz D, Johenning FW.(2011) Complementary sensory and associative microcircuitry in primary olfactory cortex.
    J. Neurosci. 2011 Aug 24;31(34):12149-58.

  • Rost BR, Nicholson P, Ahnert-Hilger G, Rummel A, Rosenmund C, Breustedt J, Schmitz D.(2011) Activation of metabotropic GABA receptors increases the energy barrier for vesicle fusion.
    J. Cell Sci. 2011 Sep 15.

  • Bähner F, Weiss EK, Birke G, Maier N, Schmitz D, Rudolph U, Frotscher M, Traub RD, Both M, Draguhn A. (2011) Cellular correlate of assembly formation in oscillating hippocampal networks in vitro.
    Proc Natl Acad Sci U S A. 2011 Jul 18.

  • Winterer J, Stempel AV, Dugladze T, Földy C, Maziashvili N, Zivkovic AR, Priller J, Soltesz I, Gloveli T, Schmitz D. (2011) Cell-type-specific modulation of feedback inhibition by serotonin in the hippocampus.
    J Neurosci. 2011 Jun 8;31(23):8464-75.

  • Heisler FF, Loebrich S, Pechmann Y, Maier N, Zivkovic AR, Tokito M, Hausrat TJ, Schweizer M, Bähring R, Holzbaur EL, Schmitz D, Kneussel M. (2011) Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons.
    Neuron. 2011 Apr 14;70(1):66-81.

  • Beed P, Bendels MH, Wiegand HF, Leibold C, Johenning FW, Schmitz D. (2010) Analysis of excitatory microcircuitry in the medial entorhinal cortex reveals cell-type-specific differences.
    Neuron. 2010 Dec 22;68(6):1059-66.

  • Schapitz IU, Behrend B, Pechmann Y, Lappe-Siefke C, Kneussel SJ, Wallace KE, Stempel AV, Buck F, Grant SG, Schweizer M, Schmitz D, Schwarz JR, Holzbaur EL, Kneussel M. (2010) Neuroligin 1 is dynamically exchanged at postsynaptic sites.
    J Neurosci. 2010 Sep 22;30(38):12733-44.

  • Sigrist SJ, Schmitz D. (2010) Structural and functional plasticity of the cytoplasmic active zone.
    Curr Opin Neurobiol. 2011 Feb;21(1):144-50. Epub 2010 Sep 9. Review.

  • Rost BR, Breustedt J, Schoenherr A, Grosse G, Ahnert-Hilger G, Schmitz (2010) D. Autaptic cultures of single hippocampal granule cells of mice and rats. Eur J Neurosci.
    2010 Sep;32(6):939-47.

  • Bendels MH, Beed P, Schmitz D, Johenning FW, Leibold C. (2010) Detection of input sites in scanning photostimulation data based on spatial correlations.
    J Neurosci Methods. 2010 Oct 15;192(2):286-95.

  • Gundlfinger A, Breustedt J, Sullivan D, Schmitz D. (2010) Natural spike trains trigger short- and long-lasting dynamics at hippocampal mossy fiber synapses in rodents.
    PLoS One. 2010 Apr 1;5(4):e9961.

  • Behr J, Wozny C, Fidzinski P, Schmitz D. (2009) Synaptic plasticity in the subiculum.
    Prog Neurobiol. 2009 Sep 19.

  • Maier N, Morris G, Johenning FW, Schmitz D. (2009) An approach for reliably investigating hippocampal sharp wave-ripples in vitro.
    PLoS One. 2009 Sep 7

  • Schmidt R, Diba K, Leibold C, Schmitz D, Buzsaki G, Kempter, R (2009) Single-trial phase precession in the hippocampus.
    J Neurosci. 2009 Oct 21;29(42)

  • Trimbuch T*, Beed P*, Vogt J*,...Schmitz D*, Nitsch R* (2009) PRG-1 is a novel player at the synapse, modulating excitatory transmission via lipid phosphate-mediated signaling.
    Cell 138, 1222–1235, September 18, 2009
    *equal contribution

  • Johenning F, Beed P, Trimbuch T, Bendels M, Winterer J, Schmitz D. (2009) Dendritic compartment and neuronal output mode determine pathway specific LTP in the piriform cortex. J Neurosci.
    J Neurosci. 2009 Oct 28;29(43)

  • Harmeier A, Wozny C, Rost BR, Munter LM, Hua H, Georgiev O, Beyermann M, Hildebrand PW, Weise C, Schaffner W, Schmitz D, Multhaup G. (2009) Amyloid-ß Glycine 33 uncouples oligomerization from toxicity and LTP inhibition. J Neurosci. 2009 Jun 10;29(23)

  • Breustedt J, Gundlfinger A, Varoqueaux F, Reim K, Brose N, Schmitz D. (2009) Munc13-2 differentially affects hippocampal synaptic transmission and plasticity. Cereb Cortex. 2009 Aug 21

  • Wozny C*, Breustedt J*, Wolk F*, Varoqueaux F, Boretius S, Zivkovic A, Neeb A, Frahm J, Schmitz D, Brose N, Ivanovic A (2009) The function of glutamatergic synapses is not perturbed by severe knock-down of 4.1N and 4.1G expression.
    J Cell Sci. 22:735-44.
    *equal contribution

  • Wozny C, Maier N, Fidzinski P, Breustedt J, Behr J, Schmitz D. (2008) Differential cyclic AMP signaling at hippocampal output synapses. J Neurosci. 31;28:14358-62

  • Wozny C, Maier N, Schmitz D*, Behr J* (2008) Two different forms of long-term potentiation at CA1-subiculum synapses. J Physiol. 586:2725- 34 *equal contribution

  • Leibold C*, Gundlfinger A*, Schmidt R, Thurley K, Schmitz D*, Kempter R* (2008) Temporal coding via synaptic facilitation. Proc Natl Acad Sci USA 105:4417-22 *equal contribution (track II)

  • Brecht M, Schmitz D (2008) Rules of plasticity.
    Science 319:39-40

  • Gundlfinger A, Leibold C, Gebert K, Moisel M, Schmitz D*, Kempter R* (2007) Differential modulation of short-term synaptic dynamics by long- term potentiation at mouse hippocampal mossy fibre synapses. J Physiol. 585:853-65. *equal contribution (see also News & Views in J Physiol.)

  • Motazacker MM, Rost BR et al. (2007) A Defect in the Ionotropic Glutamate Receptor 6 Gene (GRIK2) Is Associated with Autosomal Recessive Mental Retardation. Am J Hum Genet. 81(4):792-8.

  • Gundlfinger A, Bischofberger J, Johenning FW, Torvinen M, Schmitz D*, Breustedt J* (2007) Adenosine modulates transmission at the hippocampal mossy fibre synapse via direct inhibition of presynaptic calcium channels. J Physiol. 582:263-77. *equal contribution

  • Plath N, Ohana O, et al. (2006) Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. Neuron 52:437-444. (see also News & Views in Neuron)

  • Schuchmann S*, Schmitz D*, Rivera C, Vanhatalo S, Salmen B, Mackie K et al. (2006) Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis. Nature Medicine 12(7):817- 23. *equal contribution (see also News & Views in Nature Medicine)

  • Gundlfinger A, Schmitz D. (2005) Inactivity sets XL synapses in motion. Neuron 47(5):623-5. (2005)

  • Nicoll RA, Schmitz D (2005) Synaptic plasticity at hippocampal mossy fibre synapses. Nature Review Neurosciences 6(11):863-76.

  • Nimmrich V, Maier N, Schmitz D, Draguhn A. (2005) Induced sharp wave- ripple complexes in the absence of synaptic inhibition in mouse hippocampal slices. J Physiol. 563:663-70.

  • Breustedt J, Schmitz D. (2004) Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses. J Neurosci. 24(45):10093-8.

  • Breustedt J, Vogt KE, Miller RJ, Schmitz D (2004) α 1E-containing Ca2+- channels are involved in synaptic plasticity. Proc Natl Acad Sci USA 100(21):12450-12455.

  • Schmitz D et al. (2004) Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation. Nature Neuroscience 6:1058-1066.

  • Moore K, Nicoll RA, Schmitz D (2003) Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses. Proc Natl Acad Sci USA 100(24):14397-14402.

  • Mellor J, Nicoll RA, Schmitz D (2002) Presynaptic Ih channels mediate hippocampal mossy fiber long term potentiation. Science 295:143-7.

  • Schmitz D et al. (2002) Axo-axonal coupling: a novel mechanism for ultrafast neuronal communication. Neuron 31:831-840. (see also News & Views in Neuron and Nature Neuroscience)

  • Schmitz D, Mellor J, Nicoll RA (2001) Presynaptic kainate receptor mediation of frequency facilitation at hippocampal mossy fiber synapses. Science 291:1972-1976. (Science express with comment from Editor)

  • Frerking M, Schmitz D, Zhou Q, Johansen J, Nicoll RA. (2001) Kainate receptors depress excitatory synaptic transmission at CA3-CA1 synapses in the hippocampus via a direct presynaptic action. J Neurosci. 21:2958- 66.

  • Schmitz D, Mellor J, Frerking M, Nicoll RA (2001) Presynaptic kainate receptors at hippocampal mossy fiber synapses. Proc Natl Acad Sci USA 98: 11003-11008.

  • Traub RD, Bibbig R, Piechotta A, Draguhn R, Schmitz D. (2001) Synaptic and nonsynaptic contributions to giant ipsps and ectopic spikes induced by 4-aminopyridine in the hippocampus in vitro. J Neurophysiol. 85:1246- 56.

  • Nicoll RA, Mellor J, Frerking M, Schmitz D. (2000) Kainate receptors and synaptic plasticity. Nature 406:957.

  • Schmitz D, Frerking M, Nicoll RA (2000) Synaptic activation of presynaptic kainate receptors on hippocampal mossy fiber synapses. Neuron 27:327-338.

  • Nicoll RA, Frerking M, Schmitz D. (2000) AMPA receptors jump the synaptic cleft. Nature Neurosci. 6:527-9.

  • Traub RD, Schmitz D, Jefferys JG, Draguhn A. (1999) High-frequency population oscillations are predicted to occur in hippocampal pyramidal neuronal networks interconnected by axoaxonal gap junctions. Neurosci. 92:407-26.

  • Draguhn A, Traub RD, Schmitz D, Jefferys JGR (1998) Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro. Nature 394:189-192. (see also News & Views in Nature)

* equal contribution