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A. Referierte Originalarbeiten

1995 1996 1997 1998 1999 request reprint
2000 2001 2002 2003 2004
2005 2006 2007 2008 2009
2010 2011      

    1995
  1. Shakibaei M, Förster C, Merker H J, Stahlmann R (1995) Effects of ofloxacin on integrin expression on epiphyseal mouse chondrocytes in vitro. Toxic in vitro 9:107-116
  2. Stahlmann R, Neubert R (1995) Value of non-human primate data (Intl. Workshop on Environmental Immunotoxicology and Human Health) Hum Exp Toxicol 14:146-147
  3. Förster C, Shakibaei M, Schilcher H, Stahlmann R (1995) Expression of ß1-integrins on epiphyseal chondrocytes is reduced by ofloxacin. Drugs 49 (Suppl 2): 279-282
  4. Shakibaei M, Förster C, Merker H-J, Stahlmann R (1995) Ofloxacin alters expression of integrins on chondrocytes from mouse fetuses in vitro. Drugs 49 (Suppl 2): 293-295
  5. Stahlmann R, Förster C, Shakibaei M, Vormann J, Günther T, Merker H-J (1995) Magnesium deficiency induces joint cartilage lesions in juvenile rats which are identical to quinolone-induced arthropathy. Antimicrob Agents Chemother 39: 2013-2018
  6. Schulz TG, Stahlmann R, Edwards RJ, Debris K, Davies DS, Neubert D (1995) Enoxacin is an inducer of CYP1A2 in rat liver. Biochem Pharmacol 50: 1517-1520
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    1996

  8. Förster C, Kociok K, Shakibaei M, Merker H-J, Vormann J, Günther T, Stahlmann R (1996) Integrins on joint cartilage chondrocytes and alterations by ofloxacin or magnesium deficiency in immature rats. Arch Toxicol 70: 261-270
  9. Förster C, Kociok K, Shakibaei M, Merker H-J, Stahlmann R (1996) Quinolone-induced cartilage lesions are not reversible in rats. Arch Toxicol 70: 474-481
  10. Shakibaei M, Kociok K, Förster C, Vormann J, Günther T, Stahlmann R, Merker H-J (1996) Comparative evaluation of ultrastructural changes in articular cartilage of ofloxacin-treated and magnesium-deficient immature rats. Toxicol Pathol 24: 580-587
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    1997

  12. Günther T, Rücker M, Förster C, Vormann J, Stahlmann R (1997) In vitro evidence for a Donnan distribution of Mg2+ and Ca2+ by chondroitin sulfate in cartilage. Arch Toxicol 71: 471-475
  13. Vormann J, Förster C, Zippel U, Lozo E, Günther T, Merker HJ, Stahlmann R (1997) Effects of magnesium deficiency on magnesium and calcium content in bone and cartilage in developing rats in correlation to chondrotoxicity. Calc Tiss Intl 61: 230-238
  14. Förster C, Schwabe R, Lozo E, Zippel U,Vormann J, Günther T, Merker HJ, Stahlmann R (1997) Quinolone-induced arthropathy: Exposure of magnesium-deficient aged rats or immature rats, mineral concentrations in target tissues and pharmacokinetics. Arch Toxicol 72: 26 -32
  15. Burkhardt JE, Förster C, Lozo E, Hill MA, Stahlmann R (1997) Immunohistochemistry of articular cartilage from immature Beagle dogs dosed with difloxacin. Toxicol Pathol 25: 475-480
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    1998

  17. Stahlmann R, Zippel U, Förster C, Schwabe R, Shakibaei M, Merker HJ, Borner K (1998) Chondrotoxicity and toxicokinetics of sparfloxacin in juvenile rats. Antimicrob Agents Chemother 42: 1470-1475
  18. Förster C, Rücker M, Shakibaei M, Baumann-Wilschke I, Vormann J, Stahlmann R (1998) Effects of fluoroquinolones and magnesium deficiency in murine limb bud cultures. Arch Toxicol 72: 411-419
  19. Stahlmann R, Lode H (1998) Safety of quinolones. The Lancet (Letter) 352/9136: 1313
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    1999

  21. Stahlmann R, Schwabe R, Pfister K, Lozo E, Shakibaei M, Vormann J (1999) Supplementation with magnesium and tocopherol diminishes quinolone-induced chondrotoxicity in immature rats. Drugs 58 (Suppl 2): 393-394
  22. Stahlmann R, Kühner S, Shakibaei M, Schwabe R, van Sickle D (1999) Chondrotoxicity of ciprofloxacin in immature Beagle dogs. Drugs 58 (Suppl 2): 388-389
  23. Schwabe R, Lozo E, Baumann-Wilschke I, Stahlmann R (1999) Chondrotoxicity and target tissue kinetics of ofloxacin in immature rats after multiple doses. Drugs 58 (Suppl 2): 385-387
  24. Stahlmann R, Lode H (1999) Toxicity of quinolones. Drugs 58 (Suppl 2): 37-42
  25. Shakibaei M, Pfister K, Schwabe R, Stahlmann R (1999) Effects of ofloxacin on the ultrastructure of Achilles tendon in rats. Drugs 58 (Suppl 2): 390-392
  26. Riecke K, Stahlmann R, Palavinskas R, Alexi-Meskishvili V, Mathar W (1999) Polychlorinated dibenzodioxins and polychlorinated dibenzofurans in juvenile human thymus. Organohalogen Compounds 44: 233-236
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    2000

  28. Stahlmann R, Kühner S, Shakibaei M, Schwabe R, Flores J, Evander SA, van Sickle DC (2000) Chondrotoxicity of ciprofloxacin in immature Beagle dogs: immunohistochemistry, electron microscopy and drug plasma concentrations. Arch Toxicol 73: 564-572
  29. Stahlmann R, Kühner S, Shakibaei M, Flores J, Vormann J, van Sickle DC (2000) Effects of magnesium deficiency on joint cartilage in immature Beagle dogs: immunohistochemistry, electron microscopy and mineral concentrations. Arch Toxicol 73: 573-580
  30. Shakibaei M, Pfister K, Schwabe R, Vormann J, Stahlmann R (2000) Ultrastructure of Achilles tendons of rats treated with ofloxacin and fed a normal or magnesium-deficient diet. Antimicrob Agents Chemother 44/2: 261-266
  31. Riecke K, Schulz TG, Shakibaei M, Krause B, Chahoud I, Stahlmann R (2000) Developmental toxicity of the HIV-protease inhibitor indinavir in rats. Teratology 62: 291-300
  32. Riecke K, Nogueira AC, Alexi-Meskishvili V, Stahlmann R (2000) Cross reactivity of antibodies on thymic epithelial cells from humans and marmosets by flow-cytometry. J Med Primatol 29: 343-349 
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    2001

  34. Thiel R, Metzner S, Gericke C, Rahm U, Stahlmann R (2001) Effects of fluoroquinolones on the locomotor activity in rats. Arch Toxicol 75: 36-41
  35. Shakibaei M, Stahlmann R (2001) Ultrastructure of Achilles tendon from rats after treatment with fleroxacin. Arch Toxicol 75: 97-102
  36. Shakibaei M, de Souza P, van Sickle D, Stahlmann R (2001) Biochemical changes in Achilles tendon from juvenile dogs after treatment with ciprofloxacin or feeding a magnesium-deficient diet. Arch Toxicol 75: 369-374
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    2002

  38. Shakibaei M, Baumann-Wilschke I, Rücker M, Stahlmann R (2002) Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones. Arch Toxicol 75: 725-733.
    PMID: 11876506
  39. Lozo E, Riecke K, Schwabe R, Vormann J, Stahlmann R (2002) Synergistic effect of ofloxacin and magnesium deficiency on joint cartilage in immature rats. Antimicrob Agents Chemother 46: 1755-1759.
    PMID: 12019086
  40. Riecke K, Grimm D, Shakibaei M, Kossmehl P, Schulze-Tanzil G, Paul M, Stahlmann R (2002) Low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin increase transforming growth factor ß and cause myocardial fibrosis in marmosets (Callithrix jacchus). Arch Toxicol 76: 360-366.
    PMID: 12107654
     
  41. Riecke K, Grimm D, Shakibaei M, Kossmehl P, Schulze-Tanzil G, Paul M, Stahlmann R (2002) 2,3,7,8-Tetrachloro-dibenzo-p-dioxin induces myocardial fibrosis in marmosets (Callithrix jacchus). Organohalogen Compounds 55: 351-354. 
  42. Kappel EM, Shakibaei M, Bello A, Stahlmann R (2002) Effects of the des-F(6)-quinolone garenoxacin (BMS-284756), in comparison to those of ciprofloxacin and ofloxacin, on joint cartilage in immature rats. Antimicrob Agents Chemother 46: 3320-3322.
    PMID: 12234871
  43. Stahlmann R, Lode H (2002) Fluoroquinolones in the elderly: Safety considerations. Drugs and Aging, in press
  44. Pechere JC, Cenedese C, Muller O, Perez-Gorricho B, Ripoll M, Rossi A, Stahl JP, Stahlmann R, Tramarin A.
  45. Attitudinal classification of patients receiving antibiotic treatment for mild respiratory tract infections. Int J Antimicrob Agents. 2002 Dec;20(6):399-406.
    PMID: 12458132
  46. Stahlmann R. Clinical toxicological aspects of fluoroquinolones. Toxicol Lett. 2002 Feb 28;127(1-3):269-77.
    PMID: 12052667
  47. Platzek T, Stahlmann R, Wegener M, Lang C (2002) Allergene in kosmetischen Mitteln, Waschmitteln und Textilien. Mitt Lebensm Hyg 93: 591-616.
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    2003

  49. Stahlmann R (2002) Children as a special population at risk - quinolones as an example for xenobiotics exhibiting skeletal toxicity. Arch Toxicol. 2003 Jan;77(1):7-11.
    PMID: 12491034
  50. Schwenk M, Gundert-Remy U, Heinemeyer G, Olejniczak K, Stahlmann R, Kaufmann W, Bolt HM, Greim H, Von Keutz E, Gelbke HP. Children as a sensitive subgroup and their role in regulatory toxicology: DGPT workshop report.
  51. Arch Toxicol. 2003 Jan;77(1):2-6.
    PMID: 12491033
  52. Stahlmann R, Lode H (2003) Fluoroquinolones in the elderly: Safety considerations. Drugs and Aging 20: 289-302.
    PMID: 12641485
  53. Riecke K, Schmidt A, Stahlmann R (2003) Effects of 2,3,7,8-TCDD and PCB 126 on human thymic epithelial cells in vitro. Arch Toxicol 77: 358-364.
    PMID: 12799776
  54. Müller O, Stahlmann R (2003) Patientenerwartungen und Compliance bei der antibiotischen Therapie von Infektionen der oberen Atemwege. Chemother J 12: 13-20.
  55. Shakibaei M, Stahlmann R (2003) Ultrastructural Changes Induced by the Des-F(6)-Quinolone Garenoxacin (BMS-284756) and Two Fluoroquinolones in Achilles Tendon from Immature Rats. Arch Toxicol 77: 521-526.
    PMID: 12811465
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    2004

  57. Kastner M, Rahm U, Baumann-Wilschke I, Bello A, Stahlmann R (2004) Concentrations of the Des-F(6)-quinolone garenoxacin in plasma and joint cartilage of immature rats. Arch Toxicol 78: 61-67.
    PMID:14661070
  58. Ball P, Stahlmann R, Kubin R, Choudhri S, Owens R. (2004) Safety profile of oral and intravenous moxifloxacin: cumulative data from clinical trials and postmarketing studies. Clin Ther. 2004 Jul;26(7):940-50.
    PMID: 15336463 [PubMed - in process]
  59. Ulbrich B, Stahlmann R. (2004) Developmental toxicity of polychlorinated biphenyls (PCBs): a systematic review of experimental data. Arch Toxicol. 2004 May;78(5):252-68. Epub 2004 Apr 02. Review.
    PMID: 15064922 [PubMed - in process] - REVIEW | ELECTRONIC MATERIAL
  60. Stahlmann R, Sendzik J. (2004) [Adverse effects of anti-infectives. Undesirable effects and interactions of ketolides and oxazolidonones] Pharm Unserer Zeit. 2004;33(1):48-54. Review. German. No abstract available.
    PMID: 14968713 [PubMed - indexed for MEDLINE]
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    2005

  62. Oberemm A, Meckert C, Brandenburger L, Herzig A, Lindner Y, Kalenberg K, Krause E, Ittrich C, Kopp-Schneider A, Stahlmann R, Richter-Reichhelm HB, Gundert-Remy U. Differential signatures of protein expression in marmoset liver and thymus induced by single-dose TCDD treatment. Toxicology. 2005 Jan 5;206(1):33-48.
    PMID: 15590107 [PubMed - in process]
  63. Sendzik J, Stahlmann R (2005) Arzneimittel gegen Kopflausbefall, Toxikologie und Wirksamkeit. MMP 28:167
  64. Sendzik J, Shakibaei M, Schäfer-Korting M, Stahlmann R (2005) Fluoroquinolones cause changes in extracellular matrix, signalling proteins, metalloproteinases and caspase-3 in cultured human tendon cells. Toxicology. 2005 May 9; [Epub ahead of print]
    PMID: 15890441 [PubMed - as supplied by publisher]
  65. Kilic B, Kruse M, Stahlmann R. The in-vitro effects of quinupristin/dalfopristin, erythromycin and levofloxacin at low concentrations on the expression of different cell adhesion molecules on the surface of endothelial cells (Eahy926). Toxicology. 2006 Jan 20;218(1):30-8. Epub 2005 Nov 16.
    PMID: 16297520 [PubMed - indexed for MEDLINE]
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    2006

  67. Stahlmann R, Wegner M, Riecke K, Kruse M, Platzek T. Sensitising potential of four textile dyes and some of their metabolites in a modified local lymph node assay. Toxicology. 2006 Feb 15;219(1-3):113-23.
    PMID: 16388883 [PubMed - in process]
  68. Nottebrock C, Riecke K, Kruse M, Shakibaei M, Stahlmann R. Effects of 2,3,7,8-tetrachloro-dibenzo-p-dioxin on the extracellular matrix of the thymus in juvenile marmosets (Callithrix jacchus). Toxicology. 2006 Sep 21;226(2-3):197-207. Epub 2006 Jul 14.
    PMID: 16920245 [PubMed - in process]
  69. Kruse M, Kilic B, Flick B, Stahlmann R. Effect of quinupristin/dalfopristin on 3T3 and Eahy926 cells in vitro in comparison to other antimicrobial agents with the potential to induce infusion phlebitis. Arch Toxicol. 2006 Nov 22; [Epub ahead of print]
    PMID: 17119926 [PubMed - as supplied by publisher]
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    2007

  71. Pfister K, Mazur D, Vormann J, Stahlmann R. Diminished Ciprofloxacin-Induced Chondrotoxicity by Supplementation of Magnesium and Vitamin E in Immature Rats. Antimicrob Agents Chemother. 2007 Jan 8; [Epub ahead of print]
    PMID: 17210779 [PubMed - as supplied by publisher]
  72. Schreiner M, Peiser M, Briechle D, Stahlmann R, Zuberbier T, Wanner R. A loose-fit coculture of activated keratinocytes and dendritic cell-related cells for prediction of sensitizing potential. Allergy. 2007 Dec;62(12):1419-28.
    PMID: 17983376 [PubMed - in process]
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    2008

  74. Mazur D, Stahlmann R.
    [Drug-induced adverse pulmonary reactions]
    Dtsch Med Wochenschr. 2008 Jan;133(3):81-6. German. No abstract available.
    PMID: 18186010 [PubMed - in process]
  75. Lode HM, Schmidt-Ionas M, Stahlmann R.
    Gemifloxacin for community-acquired pneumonia. Expert Opin Investig Drugs. 2008 May;17(5):779-86.
    PMID: 18447602 [PubMed - in process]
  76. Schreiner M, Peiser M, Briechle D, Stahlmann R, Zuberbier T, Wanner R.
    A new dendritic cell type suitable as sentinel of contact allergens. Toxicology. 2008 May 4. [Epub ahead of print]
    PMID: 18547706 [PubMed - as supplied by publisher]
  77. Sendzik J, Lode H, Stahlmann R.
    Quinolone-induced arthropathy: an update focusing on new mechanistic and clinical data. Int J Antimicrob Agents. 2008 Oct 1. [Epub ahead of print]
    PMID: 18835137 [PubMed - as supplied by publisher]
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    2009

  79. Ahuja V, Schreiber C, Platzek T, Stahlmann R.
    Investigation of the sensitising and cross-sensitising potential of textile dyes and beta-lactam antibiotics using a biphasic mice local lymph node assay. Arch Toxicol. 2009 Feb 11. [Epub ahead of print]
    PMID: 19212757 [PubMed - as supplied by publisher]
  80. Ahuja V, Wanner R, Platzek T, Stahlmann R.
    Appraisal of the sensitising potential of orally and dermally administered Mercaptobenzothiazol by a biphasic protocol of the local lymph node assay. Arch Toxicol. 2009 Apr 19. [Epub ahead of print]
    PMID: 19381614 [PubMed - as supplied by publisher]
  81. Millrose M, Kruse M, Flick B, Stahlmann R.
    Effects of macrolides on proinflammatory epitops on endothelial cells in vitro. Arch Toxicol. 2009 May;83(5):469-76. Epub 2008 Dec 4. [Epub ahead of print]
    PMID: 19052724 [PubMed - as supplied by publisher]
  82. Ahuja V, Eisenblätter M, Ignatius R, Stahlmann R.
    Ammonium perfluorooctanoate substantially alters phenotype and cytokine secretion of human monocyte-derived dendritic cells in vitro. Immunopharmacol Immunotoxicol. 2009;31(4):641-6.
    PMID: 19874235 [PubMed - in process]
  83. Breitschaft A, Stahlmann R.
    [Nephrogenic systemic fibrosis]. Med Monatsschr Pharm. 2009 Oct;32(10):377-82. Review. German.
    PMID: 19886227 [PubMed - indexed for MEDLINE]
  84. Bode K, Kunz A, Baumann-Wilschke I, Shakibaei M, Stahlmann R.
    Effects of moxifloxacin and clinafloxacin on murine limb buds cultured in regular and in magnesium-deficient medium. Arch Toxicol. 2009 Dec 1. [Epub ahead of print]
    PMID: 19949773 [PubMed - as supplied by publisher]
  85. Sendzik J, Shakibaei M, Schäfer-Korting M, Lode H, Stahlmann R.
    Synergistic effects of dexamethasone and quinolones on human-derived tendon cells. Int J Antimicrob Agents. 2009 Dec 22. [Epub ahead of print]
    PMID: 20034766 [PubMed - as supplied by publisher]
  86. go top Anfang/top

    2010

  87. Eckardt K, Stahlmann R.
    Use of two validated in vitro tests to assess the embryotoxic potential of mycophenolic acid. Arch Toxicol. 2010 Jan;84(1):37-43. Epub 2009 Oct 25.
    PMID: 19856175 [PubMed - in process]
  88. Wanner R, Sonnenburg A, Quatchadze M, Schreiner M, Peiser M, Zuberbier T, Stahlmann R.
    Classification of sensitizing and irritative potential in a combined in-vitro assay. Toxicol Appl Pharmacol. 2010 Mar 8. [Epub ahead of print]
    PMID: 20219181 [PubMed - as supplied by publisher]
  89. Stahlmann R, Lode H.
    Safety considerations of fluoroquinolones in the elderly: an update. Drugs Aging. 2010 Mar 1;27(3):193-209. doi: 10.2165/11531490-000000000-00000.
    PMID: 20210367 [PubMed - in process]
  90. Bode K, Kunz A, Baumann-Wilschke I, Shakibaei M, Stahlmann R. Effects of moxifloxacin and clinafloxacin on murine limb buds cultured in regular and in magnesium-deficient medium. Arch Toxicol. 2010 Mar;84(3):221-6. Epub 2009 Dec 1. PubMed
    PMID: 19949773.
  91. Ahuja V, Platzek T, Fink H, Sonnenburg A, Stahlmann R. Study of the sensitising potential of various textile dyes using a biphasic murine local lymph node assay. Arch Toxicol. 2010 Sep;84(9):709-18. Epub 2010 Jun 29.
    PubMed PMID: 20585758
    .
  92. Sendzik J, Shakibaei M, Schäfer-Korting M, Lode H, Stahlmann R. Synergistic effects of dexamethasone and quinolones on human-derived tendon cells. Int J Antimicrob Agents. 2010 Apr;35(4):366-74. Epub 2010 Jan 19.
    PubMed PMID: 20034766
    .
  93. Breitschaft A, Stahlmann R. [Nephrogenic systemic fibrosis]. Med Monatsschr Pharm. 2009 Oct;32(10):377-82. Review. German.
    PubMed PMID: 19886227.
  94. Mielke H, Anger LT, Schug M, Hengstler JG, Stahlmann R, Gundert-Remy U. A physiologically based toxicokinetic modelling approach to predict relevant concentrations for in vitro testing. Arch Toxicol. 2010 Nov 3. [Epub ahead of print]
    PubMed PMID: 21046363
    .
  95. Ahuja V, Quatchadze M, Ahuja V, Stelter D, Albrecht A, Stahlmann R. Evaluation of biotechnology-derived novel proteins for the risk of food-allergic potential: advances in the development of animal models and future challenges. Arch Toxicol. 2010 Dec;84(12):909-17. Epub 2010 Sep 15. Review.
    PubMed PMID: 20842347
    .
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    2011

  97. Ju Q, Fimmel S, Hinz N, Stahlmann R, Xia L, Zouboulis CC. 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters sebaceous gland cell differentiation in vitro. Exp Dermatol. 2011 Apr;20(4):320-5. doi: 10.1111/j.1600-0625.2010.01204.x.
    PubMed PMID: 21410761
    .

 



 

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