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Evaluation of androgen effects of organotin compounds
| Support: |
Bundesinstitut für Risikobewertung |
| Aim: |
Organotin compounds (OTC) are used as industrial catalysators and stabilizers
and as industrial or agricultural biocides. OTCs induce effects in male
and female reproductive organs of rodents. They also cause tumors in these
organs and it is theorized that they result from endocrine disruption. The
aim of this project was to investigate the effects of two organotin compounds
(tributyltin and triphenyltin) on sexual development of male and female
pubertal rats. |
| Publication: |
Grote K; Stahlschmidt B; Talsness C; Gericke C; Appel K; Chahoud I
(2004) Effects of organotin compounds on pubertal male rats Toxicology
202 (3): 145-158
PMID:
15337578 [PubMed - indexed for MEDLINE]
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