 Gastroenterology, Div. Nutritional Medicine |
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Gastroenterology, Div. Nutritional Medicine |
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PubMed list |
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2012
Amasheh M, Luettig J, Amasheh S, Zeitz M, Fromm M, Schulzke JD (2012) Effects of quercetin on the colonic cell culture model HT-29/B6 and rat intestine in vitro. Ann. N.Y. Acad. Sci. 1258: 100-107
Barmeyer C, Erko I, Fromm A, Bojarski C, Allers C, Moos V, Zeitz M, Fromm M, Schulzke JD (2012) Ion transport and barrier function are disturbed in microscopic colitis. Ann. N.Y. Acad. Sci. 1258: 143-148 (IF 3.2) [PubMed] [WebPage] [PDF] (Original paper)
Norman K, Stobäus N, Reiß J, Schulzke J, Valentini L, Pirlich M (2012) Effect of sexual dimorphism on muscle strength in cachexia. J. Cachexia Sarcopenia Muscle 3(2): 111-116 [PubMed] [HTML] [PDF]
Batra A, Heimesaat MM, Bereswill S, Fischer A, Glauben R, Kunkel D, Scheffold A, Erben U, Kühl A, Loddenkemper C, Lehr HA, Schumann M, Schulzke JD, Zeitz M, Siegmund B (2012) Mesenteric fat – control site for bacterial translocation in colitis? Mucosal Immunol. 5(5): 580-591 (IF 7.0) [PubMed] [HTML] [PDF]
Krug SM, Günzel D, Conrad MP, Rosenthal R, Fromm A, Amasheh S, Schulzke JD, Fromm M (2012) Claudin-17 forms tight junction channels with distinct anion selectivity. Cell. Mol. Life Sci. 69(16): 2765-2778 (IF 6.6) [PubMed] [WebPage] [PDF] [Supplement]
Kuntzsch D, Bergann T, Dames P, Fromm A, Fromm M, Davis RA, Melzig MF, Schulzke JD (2012) The plant-derived glucocorticoid receptor agonist endiandrin A acts as co-stimulator of colonic epithelial sodium channels (ENaC) via SGK-1 and MAPKs. PLoS One 7(11): e49426 (print pages 1-14) (IF 4.1) [PubMed] [WebPage] [PDF]
Norman K, Pirlich M, Schulzke JD, Smoliner C, Lochs H, Valentini L, Bühner S (2012) Increased intestinal permeability in malnourished patients with liver cirrhosis. Eur. J. Clin. Nutr. 66(10): 1116-1119 (IF 2.5) [PubMed] [WebPage]
Ménard S, Lebreton C, Schumann M, Matysiak-Budnik T, Dugave C, Bouhnik Y, Malamut G, Cellier C, Allez M, Crenn P, Schulzke JD, Cerf-Bensussan N, Heyman M (2012) Paracellular versus transcellular intestinal permeability to gliadin peptides in active celiac disease. Am. J. Pathol. 180(2): 608-615 (IF 4.9) [PubMed] [HTML] [PDF]
Rosenthal R*, Günzel D* (*shared first authorship), Finger C, Krug SM, Richter JF, Schulzke JD, Fromm M, Amasheh S (2012) The effect of chitosan on transcellular and paracellular mechanisms in the intestinal epithelial barrier. Biomaterials 33(9): 2791-2800 (IF 7.4) [PubMed] [HTML] [PDF] [Supplement]
Schmidt C, Lautenschlaeger C, Collnot EM, Schumann M, Bojarski C, Schulzke JD, Lehr CM, Stallmach A (2012) Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa - a first in vivo study in human patients. J. Control. Release ###: ###-### (IF 6.5) [PubMed] [WebPage] [PDF]
Schumann M, Günzel D, Buergel N, Richter JF, Troeger H, May C, Fromm A, Sorgenfrei D, Daum S, Bojarski C, Heyman M, Zeitz M, Fromm M, Schulzke JD (2012) Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in celiac disease. Gut 61(2): 220-228 (IF 10.1) [PubMed] [HTML] [PDF] [Supplements]
Schumann M, Kamel S, Pahlitzsch ML, Lebenheim L, May C, Krauss M, Hummel M, Daum S, Fromm M, Schulzke JD (2012) Defective tight junctions in refractory celiac disease. Ann. N.Y. Acad. Sci. 1258: 43-51
Schumann M*, Winter S* (*shared first authorship), Wichner K, May C, Kühl AA, Batra A, Siegmund B, Zeitz M, Schulzke JD, Lipp M, Höpken UE (2012) CCR7 deficiency causes diarrhea associated with altered ion transport in colonocytes in the absence of overt colitis. Mucosal Immunol. 5(4): 377-387
Valentini L, Gläser S, Schuetz T, Omar A, Kasim E, Kroencke T, Tietge UJ, Lochs H, Schulzke JD, Brabant G, Ockenga J (2012) Serum bile acids and leptin interact with glucose metabolism in patients with liver cirrhosis. Clin. Nutr. ###: ###-### (IF 3.7) [PubMed] [WebPage] [PDF]
Valentini L, Roth E, Jadrna K, Postrach E, Schulzke JD (2012)
The BASA-ROT table: An arithmetic-hypothetical concept for easy BMI-, age-,
and sex-adjusted bedside estimation of energy expenditure.
Nutrition 28(7-8): 773-778
(IF 3.0)
[PubMed] [WebPage]
[PDF]
Reviews
Hering NA, Fromm M, Schulzke JD (2012) Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics. J. Physiol. 590(5): 1035-1044 (IF 4.7) [PubMed] [HTML] [PDF]
Schulzke JD, Günzel D, John LJ, Fromm M (2012) Perspectives in tight junction research. Ann. N.Y. Acad. Sci. 1257: 1-19
Editions
Fromm M, Schulzke JD, Volume Editors (2012)
2011
Bergann T, Fromm A, Borden SA, Fromm M, Schulzke JD (2011) Glucocorticoid receptor is indispensable for physiological responses to aldosterone in colonic epithelial Na+ channel induction via the mineralocorticoid receptor in a human colonic cell line. Eur. J. Cell Biol. 90(5): 432-439 [PubMed] [HTML] [PDF]
Bücker R, Krug SM, Rosenthal R, Günzel D, Fromm A, Zeitz M, Chakraborty T, Fromm M, Epple HJ, Schulzke JD (2011) Aerolysin from Aeromonas hydrophila perturbs tight junction integrity and cell lesion repair in intestinal epithelial HT-29/B6 cells. J. Infect. Dis. 204 (8): 1283-1292 [PubMed] [HTML] [PDF]
Günther U, Kusch D, Heller F, Bürgel N, Leonhardt S, Daum S, Siegmund B, Loddenkemper C, Grünbaum M, Buhr HJ, Schulzke JD, Zeitz M, Bojarski C (2011) Surveillance colonoscopy in patients with inflammatory bowel disease: comparison of random biopsy vs. targeted biopsy protocols. Int. J. Colorectal. Dis. 26(5): 667-672 [PubMed] [HTML] [PDF]
Hering NA*, Andres S* (*shared first authorship), Fromm A, van Tol EA, Amasheh M, Mankertz J, Fromm M, Schulzke JD (2011) Transforming growth factor b, a whey protein component, strengthens the intestinal barrier by upregulating claudin-4 in HT-29/B6 cells. J. Nutr. 141(5): 783-789 [PubMed] [HTML] [PDF]
Hering NA, Richter JF, Krug SM, Günzel D, Fromm A, Bohn E, Rosenthal R, Bücker R, Fromm M, Troeger H, Schulzke JD (2011) Yersinia enterocolitica induces epithelial barrier dysfunction through regional tight junction changes in colonic HT-29/B6 cell monolayers. Lab. Invest. 91(2): 310-324 [PubMed] [HTML] [PDF] [Supplement DOC]
Nielsen HL, Nielsen H, Ejlertsen T, Engberg J, Günzel D, Zeitz M, Hering NA, Fromm M, Schulzke JD, Bücker R (2011) Oral and fecal Campylobacter concisus strains perturb barrier function by apoptosis induction in HT-29/B6 intestinal epithelial cells. Plos One 6(8): e23858 (print pages 1-8) [PubMed] [HTML] [PDF]
Norman K, Pirlich M, Smoliner C, Kilbert A, Schulzke JD, Ockenga J, Lochs H, Reinhold T (2011) Cost-effectiveness of a 3-month intervention with oral nutritional supplements in disease-related malnutrition: a randomised controlled pilot study. Eur. J. Clin. Nutr. 65(6): 735-742 [PubMed] [HTML] [PDF]
Norman K, Schulzke JD (2011) Langzeiteffekte von ASS auf Kolonkarzinomrisiko und Mortalität [Positive impact of ASS on cancer incidence and mortality] Z. Gastroenterol. 49(4): 532-533 [PubMed] [HTML] [PDF]
Norman K, Schulzke JD (2011) [High-protein reduced-carbohydrate weight-loss diets: negative impact on colonic health.] Z. Gastroenterol. 49(11): 1487-1488 [PubMed] [HTML] [PDF]
Schulzke JD*, Andres S*, Amasheh M* (*shared first authorship), Fromm A, Günzel D (2011) Anti-diarrheal mechanism of the traditional remedy Uzara via reduction of active chloride secretion. PLoS One 6(3): e18107 (print 1-9) [PubMed] [HTML] [PDF]
Stobäus N, Pirlich M, Valentini L, Schulzke JD, Norman K (2011) Determinants of bioelectrical phase angle in disease. Br. J. Nutr. 28: 1-4
Valentini L, Schulzke JD (2011) Mundane, yet challenging: the assessment of malnutrition in inflammatory bowel disease. Eur. J. Intern. Med. 22(1): 13-15 [PubMed] [HTML] [PDF]
Reviews
John LJ, Fromm M, Schulzke JD (2011) Epithelial barriers in intestinal inflammation. Antioxid. Redox Signal. 15(5): 1255-1270 (IF 8.2) (Review) [PubMed] [HTML] [PDF for printing] [PDF with links]
Norman K, Stobäus N, Gonzalez MC, Schulzke JD, Pirlich M (2011) Hand grip strength: outcome predictor and marker of nutritional status. Clin. Nutr. 30(2): 135-142 [PubMed] [HTML] [PDF]
2010
Amasheh M, Fromm A, Krug SM, Amasheh S, Andres S, Zeitz M, Fromm M, Schulzke JD (2010) TNFa-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, pAkt, and NFkB signaling. J. Cell Sci. 123(23): 4145-4155 [PubMed] [HTML] [PDF] [Supplements]
Epple HJ, Allers K, Tröger H, Kühl
A, Erben U, Fromm M, Zeitz M, Loddenkemper C*, Schulzke JD*,
Schneider T* (*shared last authorship) (2010) Acute HIV infection induces
mucosal infiltration with CD4+ and CD8+ T cells, epithelial apoptosis, and a
mucosal barrier defect. Gastroenterology
139(4): 1289-1300 [PubMed]
[HTML]
[PDF]
[Supplement
PDF]
Hillenbrand B, Günzel D, Richter JF, Höhne, Schreier E, Schulzke JD, Mankertz J (2010) Norovirus non-structural protein p20 leads to impaired restitution of epithelial defects by inhibition of actin cytoskeleton remodelling. Scand. J. Gastroent. 45(11):1307-1319 [PubMed] [HTML] [PDF]
Milatz S, Krug SM, Rosenthal R, Günzel D, Müller D, Schulzke JD, Amasheh S*, Fromm M* (*shared last authorship) (2010) Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes. Biochim. Biophys. Acta Biomembr. 1798: 2048-2057 [PubMed] [HTML] [PDF]
Norman K, Schulzke JD, Pirlich M (2010) Frühstück verbessert die kognitive Funktion bei Patienten mit Leberzirrhose [Positive impact of breakfast on cognitive function in liver cirrhosis]. Z. Gastroenterol. 48(11): 1317-1318 [PubMed] [HTML] [PDF]
Rosenthal R, Milatz S, Krug SM,
Oelrich B, Schulzke JD, Amasheh S, Günzel D, Fromm M (2010) Claudin-2,
a component of the tight junction, forms a paracellular water channel.
J. Cell Sci. 123(11): 1913-1921 [PubMed]
[HTML] [PDF]
[Supplement]
Schulzke JD*,
Pfaffenbach S* (*shared first authorship), Fromm A, Epple HJ, Troeger H*,
Fromm M* (*shared last authorship) (2010) PGI2
sensory input into the ENS during distension-induced colonic chloride
secretion in rat colon. Acta Physiol.
199(3): 305-316 [PubMed]
[HTML]
[PDF] Reviews
Bücker R, Schumann M, Amasheh S, Schulzke JD (2010) Claudins in intestinal function and disease. Curr. Top. Membr. 65: 195-227 [Directory] [HTML] [PDF] (book chapter)
2009
Amasheh S, Dullat S, Fromm M, Schulzke JD, Buhr HJ, Kroesen AJ (2009) Inflamed pouch mucosa possesses altered tight junctions indicating recurrence of inflammatory bowel disease. Int. J. Colorectal Dis. 24(10): 1149-1156 [PubMed] [HTML] [PDF]
Amasheh M, Grotjohann I, Amasheh S, Fromm A, Söderholm JD, Zeitz M, Fromm M, Schulzke JD (2009) Regulation of mucosal structure and barrier function in rat colon exposed to tumor necrosis factor alpha and interferon gamma in vitro: A novel model for studying the pathomechanisms of inflammatory bowel disease cytokines. Scand. J. Gastroent. 44: 1226-1235 [PubMed] [HTML] [PDF]
Amasheh M, Kroesen AJ, Schulzke JD (2009) Short bowel syndrome: which remedy, which nutrition and which surgical options? Dtsch. Med. Wochenschr. 132: 1763-1767 [PubMed] [HTML] [PDF]
Bergann T, Plöger S, Fromm A, Zeissig S, Borden SA, Fromm M, Schulzke JD (2009) A colonic mineralocorticoid receptor cell model expressing epithelial Na+ channels. Biochem. Biophys. Res. Comm. 381(2): 280-285 [PubMed] [HTML] [PDF]
Bergann T, Zeissig S, Fromm A, Richter JF, Fromm M, Schulzke JD (2009) Glucocorticoid and tumor necrosis factor-alpha synergize to induce absorption by the epithelial sodium channel in the colon. Gastroenterology 136(3): 933-942 [PubMed] [HTML] [PDF]
Bücker R*, Troeger H* (*shared first authorship), Kleer J, Fromm M, Schulzke JD (2009) Arcobacter butzleri induces barrier dysfunction in intestinal epithelial cells. J. Infect. Dis. 200(5): 756-764 [PubMed] [HTML] [PDF]
Fromm M, Krug SM, Zeissig S, Richter JF, Rosenthal R, Schulzke JD, Günzel D (2009) High resolution analysis of barrier function. Ann. N.Y. Acad. Sci. 1165: 74-81 [PubMed] [HTML] [PDF] (Review)
Hering NA, Schulzke JD (2009) Therapeutic options to modulate barrier defects in inflammatory bowel disease. Dig. Dis. 27(4): 450-454 [PubMed] [PDF] (Review)
Krug SM, Amasheh S, Richter JF, Milatz S, Günzel D, Westphal JK, Huber O, Schulzke JD, Fromm M (2009) Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability. Mol. Biol. Cell 20: 3713-3724 [PubMed] [HTML] [PDF] [Supplement text] [Supplement video]
Kunkel J, Schmidt S, Loddenkemper C, Zeitz M, Schulzke JD (2009) Chronic diarrhea and melanosis coli caused by wellness drink. Int. J. Colorectal Dis. 24(5):595-596 (Letter) [PubMed reference] [HTML] [PDF]
Mankertz J*, Amasheh M* (*shared first authorship), Krug SM, Fromm A, Amasheh S, Hillenbrand B, Tavalali S, Fromm M, Schulzke JD (2009) TNFalpha up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling. Cell Tiss. Res. 336(1): 67-77 [PubMed] [HTML] [PDF]
Richter JF, Gitter AH, Günzel D, Weiss S, Mohamed W, Chakraborti T, Fromm M, Schulzke JD (2009) Listeriolysin O affects barrier function and induces chloride secretion in HT-29/B6 colon epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. 296(6): G1350-G1359 [PubMed] [HTML] [PDF]
Schulzke JD, Tröger H, Amasheh M (2009) Disorders of intestinal secretion and absorption. Best Pract. Res. Clin. Gastroent. 23(3): 395-406 [PubMed] [HTML] [PDF]
Troeger H, Loddenkemper C, Schneider T, Schreier E, Epple HJ, Zeitz M, Fromm M, Schulzke JD (2009) Structural and functional changes of the duodenum in human norovirus infection. Gut 58: 1070-1077 [PubMed] [HTML] [PDF]
Reviews
Amasheh M, Andres S, Amasheh S, Fromm M, Schulzke JD (2009) Barrier effects of nutritional factors. Ann. N.Y. Acad. Sci. 1165: 267-273 [PubMed] [HTML] [PDF]
Fromm M, Krug SM, Zeissig S, Richter JF, Rosenthal R, Schulzke JD, Günzel D (2009) High resolution analysis of barrier function. Ann. N.Y. Acad. Sci. 1165: 74-81 [PubMed] [HTML] [PDF]
Schulzke JD, Fromm M (2009) Tight junctions: Molecular structure meets function. Ann. N.Y. Acad. Sci. 1165: 1-6 [PubMed] [HTML] [PDF]
Schulzke JD* / Ploeger S* (*shared first authorship), Amasheh M, Fromm A, Zeissig S, Troeger H, Richter JF, Bojarski C, Schumann M, Fromm M (2009) Epithelial tight junctions in intestinal inflammation. Ann. N.Y. Acad. Sci. 1165: 294-300 [PubMed] [HTML] [PDF]
Editition
Fromm M, Schulzke JD, Volume Editors (2009) Molecular structure and function of the tight junction. Ann. N.Y. Acad. Sci. 1165, pp 1-346, 46 papers, ISBN 978-1-57331-749-8 [Contents and Full Papers] [Cover]
Textbook chapters
Fromm M, Schulzke JD (2008) Diarrhea. In: Encyclopedia of molecular mechanisms of disease. Lang F (ed), Springer, Berlin Heidelberg, ISBN 978-3-540-67136-7 (Print) 978-3-540-29676-8 (Online), Part 4, p 528-530. [Online entry] [HTML]
Schulzke JD, Fromm M (2008) Malabsorption. In: Encyclopedia of molecular mechanisms of disease. Lang F (ed), Springer, Berlin Heidelberg, ISBN 978-3-540-67136-7 (Print) 978-3-540-29676-8 (Online), Part 13, p 1250-1252. [Online entry] [HTML]
2008
Amasheh S*, Milatz S* (*shared first authorship), Krug SM, Bergs M, Amasheh M, Schulzke JD, Fromm M (2009, Epub 08.11.2008) Na+ absorption defends from paracellular back-leakage by claudin-8 upregulation. Biochem. Biophys. Res. Comm. 378(1): 45-50 [PubMed] [HTML] [PDF]
Amasheh M, Schlichter S, Amasheh S, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2008) Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells. J. Nutr. 138(6):1067-1073 [PubMed] [HTML] [PDF]
Epple HJ, Schneider T, Troeger H, Kunkel D, Allers K, Moos V, Amasheh M, Loddenkemper C, Fromm M, Zeitz M, Schulzke JD (2009, Epub 04.11.2008) Impairment of the intestinal barrier is evident in untreated but absent in suppressively treated HIV-infected patients. Gut 58: 220-227 [PubMed] [HTML] [PDF]
Heller F, Fromm A, Gitter AH, Mankertz J, Schulzke JD (2008) Epithelial apoptosis is a prominent feature of the epithelial barrier disturbance in intestinal inflammation: effect of pro-inflammatory interleukin-13 on epithelial cell function. Mucosal Immun. 1: S58-S61 [PubMed] [HTML] [PDF]
Kroesen AJ, Dullat S, Schulzke JD, Fromm M, Buhr HJ (2008) Permanently increased mucosal permeability in patients with backwashileitis after ileoanal pouch for ulcerative colitis. Scand. J. Gastroent. 43(6): 704-711 [PubMed] [HTML] [PDF]
Schumann M, Richter JF, Wedell I,
Moos V, Zimmermann-Kordmann M, Schneider T, Daum S, Zeitz M, Fromm M,
Schulzke JD
(2008) Mechanisms of epithelial translocation of the a2-gliadin-33mer
in celiac sprue.
Zeissig S, Bergann T, Fromm A, Bojarski C, Heller F, Guenther U, Zeitz M, Fromm M, Schulzke JD (2008) Altered ENaC expression leads to impaired sodium absorption in the non-inflamed intestine in Crohn's disease. Gastroenterology 134(5): 1436-1447 [PubMed] [HTML] [PDF]
Hoffmann JC, Heller F, Faiss S, von Lampe B, Kroesen AJ, Wahnschaffe U, Schulzke JD, Zeitz M, Bojarski C (2008) Through the endoscope balloon dilation of ileocolonic strictures: prognostic factors, complications, and effectiveness. Int. J. Colorectal Dis. 23: 689-696 [PubMed] [HTML] [PDF]
Schrage A, Wechsung K, Neumann K, Schumann M, Schulzke JD, Engelhardt B, Hamann M, Klugewitz K (2008) Enhanced T cell transmigration across the murine liver sinusoidal endothelium is mediated by transcytosis and surface presentation of chemokines. Hepatology 48: 1262-1272 [PubMed] [HTML] [PDF]
2007
Troeger H*, Richter JF* (*shared first authorship), Beutin L, Günzel D, Dobrindt U, Epple HJ, Gitter AH, Zeitz M, Fromm M, Schulzke JD (2007) E. coli alpha-hemolysin induces focal leaks in colonic epithelium – a novel mechanism of bacterial translocation. Cell. Microbiol. 9(10): 2530-2540 [PubMed] [HTML] [PDF]
Troeger H, Epple HJ, Schneider T,
Wahnschaffe U, Ullrich R, Burchard GD, Jelinek T, Zeitz M, Fromm M,
Schulzke JD (2007) Effect of chronic Giardia lamblia infection
on epithelial transport and barrier function in human duodenum.
Zeissig S, Fromm A, Mankertz J, Weiske J, Zeitz M, Fromm M, Schulzke JD (2007) Butyrate induces intestinal sodium absorption via Sp3-mediated transcriptional up-regulation of epithelial sodium channels. Gastroenterology 132(1): 236-248 [PubMed] [HTML] [PDF]
Zeissig S, Bürgel N, Günzel D, Richter JF, Mankertz J, Wahnschaffe U, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD (2007) Changes in expression and distribution of claudin-2, -5 and -8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut 56(1): 61-72 [PubMed] [HTML] [PDF]
Jorgensen VL, Ibsen M, Andresen L, Schulzke JD, Perner A (2007) Effects of endotoxaemia on markers of permeability, metabolism and inflammation in the large bowel of healthy subjects. Acta Anaesthesiol. Scand. 51: 1085-1092 [PubMed] [HTML] [PDF]
Wahnschaffe U, Schulzke JD, Zeitz M, Ullrich R (2007) Predictors of clinical response to gluten-free diet in patients diagnosed with diarrhea-predominant irritable bowel syndrome. Clin. Gastroenterol. Hepatol. 5: 844-850 [PubMed] [HTML] [PDF]
Reviews
Mankertz J, Schulzke JD (2007) Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications. Curr. Opin. Gastroenterol. 23: 379-383 [PubMed] [HTML/PDF]
2006
Epple HJ*, Loddenkemper C*, Kunkel D* (*shared first authorship), Troeger H, Maul J, Moos V, Berg E, Ullrich R, Schulzke JD, Stein H, Duchmann R, Zeitz M, Schneider T (2006) Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART. Blood 108: 3072-3078 [PubMed] [HTML] [PDF]
Günzel D*, Florian P* (*shared first authorship), Richter JF, Troeger H, Schulzke JD, Fromm M, Gitter AH (2006) Restitution of single-cell defects in the mouse colon epithelium differs from that of cultured cells. Am. J. Physiol. - Reg. Integ. Comp. Physiol. 290: R1496-R1507 [PubMed] [HTML] [PDF] [Supplemental videos]
Kroesen AJ, Leistenschneider P, Lehmann K, Ransco C, Dullat S, Blaut M, Schulzke JD, Fromm M, Buhr HJ (2006) Increased bacterial permeation in long-lasting ileoanal pouches. Inflamm. Bowel Dis. 12(8): 736-744 [PubMed] [HTML and PDF]
Reiter B, Kraft R, Günzel D, Zeissig S, Schulzke JD, Fromm M, Harteneck C (2006) TRPV4-mediated regulation of epithelial permeability. FASEB J. 20: 1802-1812 [PubMed] [HTML] [PDF]
Schulzke JD, Bojarski C, Zeissig S, Heller F, Gitter AH, Fromm M (2006) Disrupted barrier function through epithelial cell apoptosis. Ann. N.Y. Acad. Sci. 1072: 288-299 [PubMed] [PDF] [Publisher's ad]
Zeissig S, Fromm A, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2006) Restoration of ENaC expression by glucocorticoid receptor transfection in human HT-29/B6 colon cells. Biochem. Biophys. Res. Commun. 344(4): 1065-1070 [PubMed] [HTML] [PDF]
2005
Bode H, Lenzner L, Kraemer OH, Bendfeldt K, Schulzke JD, Fromm M, Stoltenburg-Didinger G, Zeitz M, Ullrich R (2005) The HIV protease inhibitors saquinavir, ritonavir, and nelfinavir induce apoptosis and decrease barrier function in human intestinal epithelial cells. Antivir. Ther. 10(5): 645-655 [PubMed] [PDF]
Heller F, Florian P, Bojarski C, Richter JF, Christ M, Hillenbrand B, Mankertz J, Gitter AH, Bürgel N, Fromm M, Zeitz M, Fuss I, Strober W, Schulzke JD (2005) Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis and cell restitution. Gastroenterology 129(2): 550-564 [PubMed] [HTML] [PDF]
Schulzke JD, Gitter AH, Mankertz J, Spiegel S, Seidler U, Amasheh S, Saitou M, Tsukita S, Fromm M (2005) Epithelial transport and barrier function in occludin-deficient mice. Biochim. Biophys. Acta - Biomembranes 1669(1): 34-42 [PubMed] [HTML] [PDF]
2004
Amasheh S, Barmeyer C, Koch CS, Tavalali S, Mankertz J, Epple HJ, Gehring MM, Florian P, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD (2004) Cytokine-dependent transcriptional down-regulation of epithelial sodium channel (ENaC) in ulcerative colitis. Gastroenterology 126: 1711-1720 [PubMed] [HTML] [PDF]
Barmeyer C*, Amasheh S* (*shared first authorship), Tavalali S, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2004) IL-1beta and TNFalpha regulate sodium absorption in rat distal colon. Biochem. Biophys. Res. Comm. 317: 500-507 [PubMed] [HTML] [PDF]
Barmeyer C, Harren M, Schmitz H, Heizel-Pleines U, Mankertz J, Seidler U, Horak I, Wiedenmann B, Fromm M, Schulzke JD (2004) Mechanisms of diarrhea in the interleukin-2 deficient mouse model of colonic inflammation. Am. J. Physiol. Gastrointest. Liver Physiol. 286: G244-G252 [PubMed] [HTML] [PDF]
Bojarski C, Weiske J, Schöneberg T, Schröder W, Mankertz J, Schulzke JD, Florian P, Fromm M, Tauber R, Huber O (2004) The specific fate of tight junction proteins in apoptotic epithelial cells. J. Cell Sci. 117: 2097-2107 [PubMed] [HTML] [PDF]
Epple HJ, Mankertz J, Ignatius R, Liesenfeld O, Fromm M, Zeitz M, Chakraborty T, Schulzke JD (2004) Aeromonas hydrophila beta-hemolysin induces active chloride secretion in colon epithelial cells (HT-29/B6). Infect. Immun. 72(8): 4848-4858 [PubMed] [HTML] [PDF]
Mankertz J*, Hillenbrand B* (*shared first authorship), Tavalali S, Huber O, Fromm M, Schulzke JD (2004) Functional crosstalk between Wnt signaling and Cdx-related transcriptional activation in the regulation of the claudin-2 promoter activity. Biochem. Biophys. Res. Comm. 314(4): 1001-1007 [PubMed] [HTML] [PDF]
Zeissig S*, Bojarski C* (*shared first authorship), Bürgel N, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2004) Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by TNFalpha antibody treatment. Gut 53: 1295-1302 [PubMed] [HTML] [PDF]
Jansen A, Beyer A, Brandt C, Höhne M, Schreier E, Schulzke JD, Zeitz M, Schneider T (2004) The norovirus-epidemic in Berlin - Clinic, epidemiology, and prevention. Z. Gastroenterol. 42: 311-316 [PubMed] [HTML] [PDF]
Kersting S, Bruewer M, Schuermann G, Klotz A, Utech M, Hansmerten M, Krieglstein CF, Senninger N, Schulzke JD, Naim NY, Zimmer KP (2004). Antigen transport and cytoskeletal characteristics of a distinct enterocyte population in inflammatory bowel diseases. Am. J. Pathol. 165: 425-437 [PubMed] [HTML] [PDF]
2003
Barmeyer C, Horak I, Zeitz M, Fromm M, Schulzke JD (2003) The Interleukin-2-deficient mouse model. Pathobiology 70(3): 139-142 [PubMed] [Full text]
2002
Amasheh S, Meiri N, Gitter AH, Schöneberg T, Mankertz J, Schulzke JD, Fromm M (2002) Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells. J. Cell Sci. 115(24): 4969-4976 [PubMed] [HTML] [PDF]
Bürgel N, Bojarski C, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2002) Mechanisms of diarrhea in collagenous colitis. Gastroenterology 123(2): 433-443 [PubMed] [HTML] [PDF]
Florian P, Schöneberg T, Schulzke JD, Fromm M, Gitter AH (2002) Single-cell epithelial defects close rapidly by an actinomyosin purse string mechanism with functional tight junctions. J. Physiol. (Lond.) 545(2): 485-499 [PubMed] [HTML] [PDF] [Supplementary movies]
Kroesen AJ, Stockmann M, Ransco C, Schulzke JD, Fromm M, Buhr HJ (2002) Impairment of epithelial transport but not of barrier function in idiopathic pouchitis after ulcerative colitis. Gut 50(6): 821-826 [PubMed] [HTML] [PDF]
Mankertz J, Waller JS, Hillenbrand B, Tavalali S, Florian P, Schöneberg T, Fromm M, Schulzke JD (2002) Gene expression of the tight junction protein occludin includes differential splicing and alternative promoter usage. Biochem. Biophys. Res. Comm. 298: 657-666 [PubMed] [PDF]
Schmitz H, Rokos K, Florian P, Gitter AH, Fromm M, Scholz P, Ullrich R, Zeitz M, Pauli G, Schulzke JD (2002) Supernatants of HIV-infected immune cells affect the barrier function of human HT-29/B6 intestinal epithelial cells. AIDS 16(7): 983-991 [PubMed] [HTML or PDF]
Tebbe B, Mankertz J, Schwarz C, Amasheh S, Fromm M, Schultz-Ehrenburg U, Sánchez Ruderisch H, Schulzke JD, Orfanos CE (2002) Tight junction proteins: A novel class of integral membrane proteins. Expression in human epidermis and HaCaT keratinocytes. Arch. Dermatol. Res. 294: 14-18 [PubMed] [HTML] [PDF]
Buergel N, Schulzke JD, Zeitz M (2002) Appendectomy reduces the risk of development of ulcerative colitis. Chirurg 73: 805-808 [PubMed] [HTML] [PDF]
2001
Bojarski C, Gitter AH, Bendfeldt K, Mankertz J, Schmitz H, Wagner S, Fromm M, Schulzke JD (2001) Permeability of HT-29/B6 colonic epithelium as a function of apoptosis. J. Physiol. (Lond.) 535(2): 541-552 [PubMed] [HTML] [PDF]
Epple HJ, Fromm M, Riecken EO, Schulzke JD (2001) Antisecretory effect of loperamide in colon epithelial cells by inhibition of basolateral K+ conductance. Scand. J. Gastroent. 36: 731-737 [PubMed] [PDF]
Gitter AH, Wullstein F, Fromm M, Schulzke JD (2001) Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging. Gastroenterology 121: 1320-1328 [PubMed] [HTML] [PDF]
Wahnschaffe U, Ullrich R, Riecken EO, Schulzke JD (2001). Celiac disease-like abnormalities in a subgroup of patients with irritable bowel syndrome. Gastroenterology 121:1329-1338 [PubMed] [HTML] [PDF]
Book chapter
Schulzke JD, Fromm M (2001) Tight junctions in intestinal inflammation. In: Tight junctions, 2nd edn., Anderson J, Cereijido M, eds., CRC Press, Boca Raton, ISBN 0-8493-2383-5, p 553-574 [Publisher's ad] [Retailer's ad]
2000
Bojarski C, Epple HJ, Kirstein FW, Fromm M, Bisson S, Riecken EO, Schulzke JD (2000) Patients with dyspepsia benefit from eradication of Helicobacter pylori if other organic causes for dyspepsia were carefully ruled out. Z. Gastroenterol. 38(3): 211-219 [PubMed]
Epple HJ, Amasheh S, Mankertz J, Goltz M, Schulzke JD, Fromm M (2000) Early aldosterone effect in distal colon by transcriptional regulation of ENaC subunits. Am. J. Physiol. 278(5): G718-G724 [PubMed] [HTML] [PDF]
Gitter AH, Bendfeldt K, Schmitz H, Schulzke JD, Bentzel CJ, Fromm M (2000) Epithelial barrier defects in HT-29/B6 colonic cell monolayers induced by tumor necrosis factor-alpha. Ann. N.Y. Acad. Sci. 915: 193-203. [PubMed] [Full text]
Gitter AH, Bendfeldt K, Schulzke JD, Fromm M (2000a) Trans-/paracellular, surface/crypt, and epithelial/subepithelial resistances of mammalian colonic epithelia. Pflügers Arch. 439(4): 477-482. [PubMed] [PDF] [Related articles]
Gitter AH, Bendfeldt K, Schulzke JD, Fromm M (2000b) Leaks in the epithelial barrier caused by spontaneous and TNFa-induced single-cell apoptosis. FASEB J. 14(12): 1749-1753 [PubMed] [HTML] [PDF]
Mankertz J, Tavalali S, Schmitz H, Mankertz A, Riecken EO, Fromm M, Schulzke JD (2000) Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma. J. Cell Sci. 113(Pt 11): 2085-2090 [PubMed] [PDF] [GenBank: Homo sapiens occludin gene, partial sequence]
Saitou M, Furuse M, Sasaki H, Schulzke JD, Fromm M, Takano H, Noda T, Tsukita S (2000) Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol. Biol. Cell 11(12): 4131-4142 [PubMed] [HTML] [PDF]
Radenhausen M, Schulzke JD, Geilen CC, Mansmann U, Treudler R, Bojarski C, Orfanos CE, Tebbe B (2000) Frequent presence of Helicobacter pylori infection in chronic urticaria. Acta Derm. Venerol. 80: 48-49 [PubMed] [HTML] [PDF]
Mullin JM, Russell WR, Reindl DV, Schulzke JD (2000) Electrophysiological differences in normal mucosa from divertivular disease versus cancer. Dig. Dis. Sci. 45: 2374-2375 [PubMed] [HTML] [PDF]
Wahnschaffe U, Riecken EO, Schulzke JD (2001) Diagnostik der Sprue. Dtsch. Med. Wschr. 126: 638-642 [PubMed] [HTML] [PDF]
Ann. N.Y. Acad. Sci. 915
Schulzke JD, Fromm M, Riecken EO, Binder H, Volume Editors (2000) Epithelial transport and barrier function: pathomechanisms in gastrointestinal disorders. Ann. N.Y. Acad. Sci. 915: 375 pp. [Contents & links]
Amasheh S, Epple HJ, Mankertz J, Detjen K, Goltz M, Schulzke JD, Fromm M (2000) Differential regulation of ENaC by aldosterone in rat early and late distal colon. Ann. N.Y. Acad. Sci. 915: 92-94. [PubMed reference] [Full text]
Bode H, Schmidt W, Schulzke JD, Fromm M, Riecken EO, Ullrich R (2000) Effects of HIV protease inhibitors on barrier function in the human intestinal cell line HT-29/B6. Ann. N.Y. Acad. Sci. 915: 117-122. [PubMed reference] [Full text]
Bojarski C, Bendfeldt K, Gitter AH, Mankertz J, Fromm M, Wagner S, Riecken EO, Schulzke JD (2000) Apoptosis and intestinal barrier function. Ann. N.Y. Acad. Sci. 915: 270-274. [PubMed summary] [Full text]
Bühner S, Mayr B, Bode H, Schmitz H, Schulzke JD, Fromm M, Lochs H (2000) Effects of endotoxin on human large intestine. Ann. N.Y. Acad. Sci. 915: 264-266. [PubMed reference] [Full text]
Gitter AH, Bendfeldt K, Schmitz H, Schulzke JD, Bentzel CJ, Fromm M (2000) Epithelial barrier defects in HT-29/B6 colonic cell monolayers induced by tumor necrosis factor-alpha. Ann. N.Y. Acad. Sci. 915: 193-203. [PubMed summary] [Full text]
Grotjohann I, Schmitz H, Fromm M, Schulzke JD (2000) Effect of TNF alpha and IFN gamma on epithelial barrier function in rat rectum in vitro. Ann. N.Y. Acad. Sci. 915: 282-286. [PubMed reference] [Full text]
Harren M, Barmeyer C, Schmitz H, Fromm M, Horak I, Dignass A, John M, Wiedenmann B, Schulzke JD (2000) Enhanced expression of iNOS in inflamed colons of IL-2-deficient mice does not impair colonic epithelial barrier function. Ann. N.Y. Acad. Sci. 915: 204-213. [PubMed summary] [Full text]
Kroesen AJ, Stockmann M, Schulzke JD, Fromm M, Buhr HJ (2000) Colectomy and ileal pouch. Transport and barrier in pouchitis. Ann. N.Y. Acad. Sci. 915: 287-292. [PubMed reference] [Full text]
Schmitz H, Barmeyer C, Gitter AH, Wullstein F, Bentzel CJ, Fromm M, Riecken EO, Schulzke JD (2000) Epithelial barrier and transport function of the colon in ulcerative colitis. Ann. N.Y. Acad. Sci. 915: 312-326. [PubMed reference] [Full text]
Stockmann M, Schmitz H, Fromm M, Schmidt W, Pauli G, Scholz P, Riecken EO, Schulzke JD (2000) Mechanisms of epithelial barrier impairment in HIV infection. Ann. N.Y. Acad. Sci. 915: 293-303. [PubMed summary] [Full text]
1999
Bode H, Schmidt W, Schulzke JD, Fromm M, Zippel T, Wahnschaffe U, Bendfeldt K, Riecken EO, Ullrich R (1999) The HIV protease inhibitors saquinavir, ritonavir, and nelfinavir, but not indinavir, impair the epithelial barrier in the human intestinal cell line HT-29/B6. AIDS 13(18): 2595-2597. [PubMed reference] [PDF] [Related articles]
Grotjohann I, Schulzke JD, Fromm M (1999) Electrogenic Na+ transport in rat late distal colon by natural and synthetic glucocorticosteroids and their metabolites. Am. J. Physiol. 276: G491-G498. [PubMed] [HTML] [PDF]
Schmitz H, Barmeyer C, Fromm M, Runkel N, Foss HD, Bentzel CJ, Riecken EO, Schulzke JD (1999) Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology 116: 301-309. [PubMed] [HTML] [PDF] [DCCV-Preis 1999 / award of the DCCV]
Schmitz H, Fromm M, Bentzel CJ, Scholz P, Detjen K, Mankertz J, Bode H, Epple HJ, Riecken EO, Schulzke JD (1999) Tumor necrosis factor-alpha (TNFa) regulates the epithelial barrier in the human intestinal cell line HT-29/B6. J. Cell Sci. 112: 137-146. [PubMed] [PDF]
Stockmann M, Gitter AH, Sorgenfrei D, Fromm M, Schulzke JD (1999) Low edge damage container insert that adjusts intestinal forceps biopsies into Ussing chamber systems. Pflügers Arch. 438: 107-112. [PubMed] [PDF]
1998
Bode H, Schmitz H, Fromm M, Scholz P, Riecken EO, Schulzke JD (1998) IL1b and TNFa, but not IFNa, IFNg, IL6 or IL8, are secretory mediators in human distal colon. Cytokine 10: 457-465. [PubMed] [PDF]
Gitter AH, Fromm M, Schulzke JD (1998) Impedance analysis for determination of epithelial and subepithelial resistance in intestinal tissues. J. Biochem. Biophys. Meth. 37: 35-46. [PubMed] [PDF]
Gitter AH, Victor L, Bertog M, Foss HD, Schulzke JD, Fromm M (1998) Cartography of barrier defects in human colon by low-resolution conductance scanning. Ann. N.Y. Acad. Sci. 859: 285-928. [PubMed reference] [HTML] [PDF]
Grotjohann I, Gitter AH, Köckerling A, Bertog M, Schulzke JD, Fromm M (1998) Localization of cAMP- and aldosterone-induced K+ secretion in rat distal colon by conductance scanning. J. Physiol. (Lond.) 507: 561-570. [PubMed] [HTML] [PDF]
Grotjohann I, Gitter AH, Hoppe B, Schulzke JD, Fromm M (1998) Ion transport in rat colon measured by medium-resolution conductance scanning. Ann. N.Y. Acad. Sci. 859: 300-303. [PubMed reference] [HTML] [PDF]
Hotz HG, Foitzik T, Rohweder J, Schulzke JD, Fromm M, Runkel NSF, Buhr HJ (1998) Intestinal microcirculation and gut permeability in acute pancreatitits: early changes and therapeutic implications. J. Gastrointest. Surg. 2: 518-525. [PubMed] [PDF]
Kirstein FW, Epple HJ, Bojarski C, Victor L, Fromm M, Riecken EO, Schulzke JD (1998) Dual versus triple therapy: comparison of 5 antibiotic regimens for eradication of Helicobacter pylori in a prospective, randomized study. Z. Gastroenterol. 36: 803-809. [PubMed] [PDF]
Schulzke JD, Bentzel CJ, Schulzke I, Riecken EO, Fromm M (1998) Epithelial tight junction structure in the jejunum of children with acute and treated celiac sprue. Pediatric Res. 43: 435-441. [PubMed] [HTML]
Schulzke JD, Schmitz H, Fromm M, Bentzel CJ, Riecken EO (1998) Clinical models of intestinal adaptation. Ann. N.Y. Acad. Sci. 859: 127-138. [PubMed summary] [HTML] [PDF]
Stockmann M, Fromm M, Riecken EO, Schulzke JD (1998) Non-malabsorptive mechanisms of diarrhea in HIV infection. Pathobiology 66: 165-169. [PubMed] [PDF]
Stockmann M, Fromm M, Schmitz H, Schmidt W, Riecken EO, Schulzke JD (1998) Duodenal biopsies of HIV infected patients with diarrhea show epithelial barrier defects but no secretion. AIDS 12(1): 43-51. [PubMed] [HTML] [PDF]
Stockmann M, Schmitz H, Fromm M, Schmidt W, Rokos K, Pauli G, Scholz P, Riecken EO, Schulzke JD (1998) The mechanism of diarrhea in HIV is based on an impaired epithelial barrier function that could be induced by a specific cytokine pattern. Ann. N.Y. Acad. Sci. 859: 267-270. [PubMed reference] [HTML] [PDF]
Wahnschaffe U, Zippel T, Schmidt W, Schneider T, Schulzke JD, Riecken EO, Ullrich R (1998) Serum antibodies to dietary antigens in patients with HIV-1 infection. AIDS 12(12): 1553-1555 [PubMed reference] [HTML]
Riecken EO, Daum S, Schulzke JD, Dieterich W, Schuppan D (1998) [Tissue transglutaminase as autoantigen in endemic sprue. New aspects in diagnosis and etiopathogenesis] Dtsch. Med. Wschr. 123: 1454-1460 [PubMed reference] [PDF]
1997
Epple HJ, Kirstein FW, Bojarski C, Frege J, Fromm M, Riecken EO, Schulzke JD (1997) 13C-urea breath test in Helicobacter pylori diagnosis and eradication: correlation to histology, origin of "false" results, and influence of food intake. Scand. J. Gastroent. 32: 308-314. [PubMed] [PDF]
Epple HJ, Kreusel KM, Hanski C, Schulzke JD, Riecken EO, Fromm M (1997) Differential stimulation of intestinal mucin secretion by cholera toxin and carbachol. Pflügers Arch. 433: 638-647. [PubMed] [PDF]
Foitzik T, Stufler M, Hotz HG, Klinnert J, Wagner J, Warshaw AL, Schulzke JD, Fromm M, Buhr HJ (1997) Glutamine stabilizes intestinal permeability and reduces pancreatic infection in acute experimental pancreatitis. J. Gastrointest. Surg. 1: 40-47. [PubMed] [PDF]
Gitter AH, Bertog M, Schulzke JD, Fromm M (1997) Measurement of paracellular epithelial conductivity by conductance scanning. Pflügers Arch. 434: 830-840. [PubMed] [PDF]
Gitter AH, Schulzke JD, Sorgenfrei D, Fromm M (1997) Ussing chamber for high-frequency transmural impedance analysis of epithelial tissues. J. Biochem. Biophys. Meth. 35(2): 81-88. [PubMed] [HTML] [PDF]
Schmidt W, Schneider T, Heise W, Schulzke JD, Weinke T, Ignatius R, Owen RL, Zeitz M, Riecken EO, Ullrich R (1997) Mucosal abnormalities in microsporidiosis. AIDS 11(13): 1589-1594 [PubMed] [HTML] [PDF]
1995 - 1996
Epple HJ, Schulzke JD, Schmitz H, Fromm M (1995) Enzyme and mineralocorticoid receptor controlled electrogenic Na+ absorption in the human rectum, in vitro. Am. J. Physiol. 269: G42-G48. [PubMed] [PDF]
Schmitz H, Fromm M, Bode H, Scholz P, Riecken EO, Schulzke JD (1996) Tumor necrosis factor alpha induces Cl- and K+ secretion in human distal colon driven by prostaglandin E2. Am. J. Physiol. 271: G669-G674. [PubMed] [PDF]
Schulzke JD, Riecken EO, Fromm M (1995) Distension-induced electrogenic Cl- secretion is mediated via VIP-ergic neurons in rat rectal colon. Am. J. Physiol. 268: G725-G731. [PubMed] [PDF]
Schulzke JD, Schulzke I, Fromm M, Riecken EO (1995) Epithelial barrier and ion transport in celiac sprue: electrical measurements on intestinal aspiration biopsies. Gut 37: 777-782. [PubMed] [Gut abstract+citations] [PDF]
Tebbe B, Geilen CC, Schulzke JD, Bojarski C, Radenhausen M, Orfanos CE (1996) Helicobacter pylori infection and chronic urticaria. J. Am. Acad. Dermatol. 34(4): 685-686 [PubMed reference] [PDF]
1994 - 1995
Fromm M, Schulzke JD (1994) Parazellulärer Nährstofftransport: Fakten und Irrtümer [Paracellular sugar transport: facts and doubts]. Z. Gastroent. 32: 30-34 [Review article] [Summary]
Gogarten W, Köckerling A, Fromm M, Riecken EO, Schulzke JD (1994) Effect of acute Yersinia Enterocolitica infection on intestinal barrier function in the mouse. Scand. J. Gastroent. 29: 814-819. [PubMed] [PDF]
Fromm M, Schulzke JD, Hegel U (1993) Control of electrogenic Na+ absorption in rat late distal colon by nanomolar aldosterone added in vitro. Am. J. Physiol. 264: E68-E73. [PubMed] [PDF]
Schulzke JD, Fromm M, Gogarten W, Gebhard H, Schröder P, Riecken EO (1993) Epithelial ion transport in the ileal J-pouch after proctocolectomy in the rat. Scand. J. Gastroent. 28: 533-539. [PubMed] [PDF]
1991 - 1992
Schulzke JD, Fromm M, Bentzel CJ, Zeitz M, Menge H, Riecken EO (1992) Ion transport in the experimental short bowel syndrome of the rat: increased glucose-dependent Na-absorption is the main adaptive response. Gastroenterology 102: 497-504. [PubMed] [PDF]
Kreusel KM, Fromm M, Schulzke JD, Hegel U (1991) Cl- secretion in epithelial monolayers of mucus-forming human colon cells (HT-29/B6). Am. J. Physiol. 261: C574-C582. [PubMed] [PDF]
1990
Fromm M, Schulzke JD, Hegel U (1990) Aldosterone low dose, short term action in adrenalectomized glucocorticoid-substituted rats: Na, K, Cl, HCO3, osmolyte, and water transport in proximal and rectal colon. Pflügers Arch. 416: 573-579. [PubMed] [PDF]
Fromm M, Tykocinski M, Schulzke JD, Hegel U, Bentzel CJ (1990) pH-dependence of protamine action on apical membrane permeability in Necturus gallbladder epithelium. Biochim. Biophys. Acta 1027: 179-184. [PubMed] [PDF]
Schulzke JD, Fromm M, von Hippel C, Sandforth W, Menge H, Bentzel CJ, Riecken EO (1990) Adaptation of epithelial ion transport in the short bowel syndrome. Digestion 46: 467-471. [PubMed]
Schulzke JD, Fromm M, Riecken EO, Reutter W (1990) Enkephalin affects ion transport via the enteric nervous system in guinea pig ileum. Eur. J. Clin. Invest. 20: 182-191. [PubMed]
Schulzke JD, Fromm M, Zeitz M, Menge H, Riecken EO, Bentzel CJ (1990) Tight junction regulation during impaired ion transport in blind loops of rat jejunum. Res. Exp. Med. 190: 59-68. [PubMed]
1989
Schulzke JD, Fromm M, Hegel U, Riecken EO (1989) Ion transport and enteric nervous system (ENS) in rat rectal colon: Mechanical stretch causes electrogenic Cl-secretion via Plexus Meissner and amiloride-sensitive electrogenic Na-absorption is not affected by intramural neurons. Pflügers Arch. 414: 216-221. [PubMed] [PDF]
Riecken EO, Stallmach A, Zeitz M, Schulzke JD, Menge H, Gregor M (1989) Growth and transformation of the small intestinal mucosa - importance of connective tissue, gut-associated lymphoid tissue and gastrointestinal regulary peptides. Gut 30: 1630-1640 [PubMed] [PDF]
Schulzke JD, Riecken EO (1989) [Principles of epithelial transport mechanisms: importance for pathophysiologic understanding, differential diagnosis and treatment of diarrheal diseases.] Z. Gastroenterol. 27(11): 693-700 [PubMed]
1988 - 1987
Josic D, Hofmann W, Habermann R, Schulzke JD, Reutter W (1988) Isolation of Immunglobulins and their use in Immunoaffinity HPLC. J. Clin. Chem. Clin. Biochem. 26: 559-568 [PubMed]
Schulzke JD, Tauber R, Reutter W (1988) Incorporation of non-acetylated hexosamines into plasma membrane glycoproteins of liver cells after galactosamine injection. Biol. Chem. Hoppe Seyler 369: 957-964 [PubMed]
Schulzke JD, Fromm M, Bentzel CJ, Menge H, Riecken EO (1987) Adaptation of the jejunal mucosa in the experimental blind loop syndrome: changes in paracellular conductance and tight junction structure. Gut 28: 159-164. [PubMed] [PDF]
Schulzke JD, Fromm M, Menge H, Riecken EO (1987) Impaired intestinal sodium and chloride transport in the blind loop syndrome of the rat. Gastroenterology 92: 693-698. [PubMed] [PDF]
1986 - 1985
Schulzke JD, Fromm M, Hegel U (1986) Epithelial and subepithelial resistance of rat large intestine: Segmental differences, effect of stripping, time course, and action of aldosterone. Pflügers Arch. 407: 632-637. [PubMed] [PDF]
Schulzke JD, Fromm M, Menge H, Reutter W, Riecken EO (1986) Die neurogene Steuerung der Chlorid-Sekretion der Ileumschleimhaut [Neurogenic control of chloride secretion of the ileal mucosa]. Z. Gastroent. 24: 62-69. [PubMed reference]
Fromm M, Schulzke JD, Hegel U (1985) Epithelial and subepithelial contributions to transmural electrical resistance of intact rat jejunum, in vitro. Pflügers Arch. 405: 400-402. [PubMed] [PDF]
