 Institute of Clinical Physiology |
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Institute of Clinical Physiology |
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Publications: Anja Fromm
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PubMed list |
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2012
Barmeyer C, Erko I, Fromm A, Bojarski C, Allers C, Moos V, Zeitz M, Fromm M, Schulzke JD (2012) Ion transport and barrier function are disturbed in microscopic colitis. Ann. N.Y. Acad. Sci. 1258: 143-148
Krug SM, Günzel D, Conrad MP, Rosenthal R, Fromm A, Amasheh S, Schulzke JD, Fromm M (2012) Claudin-17 forms tight junction channels with distinct anion selectivity. Cell. Mol. Life Sci. 69(16): 2765-2778
Kuntzsch D, Bergann T, Dames P, Fromm A, Fromm M, Davis RA, Melzig MF, Schulzke JD (2012) The plant-derived glucocorticoid receptor agonist endiandrin A acts as co-stimulator of colonic epithelial sodium channels (ENaC) via SGK-1 and MAPKs. PLoS One 7(11): e49426 (print pages 1-14) (IF 4.1) [PubMed] [WebPage] [PDF]
Schumann M, Günzel D, Buergel N, Richter JF, Troeger H, May C, Fromm A, Sorgenfrei D, Daum S, Bojarski C, Heyman M, Zeitz M, Fromm M, Schulzke JD (2012) Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in celiac disease. Gut 61(2): 220-228 (IF 10.1) [PubMed] [HTML] [PDF] [Supplements]
2011
Bergann T, Fromm A, Borden SA, Fromm M, Schulzke JD (2011) Glucocorticoid receptor is indispensable for physiological responses to aldosterone in colonic epithelial Na+ channel induction via the mineralocorticoid receptor in a human colonic cell line. Eur. J. Cell Biol. 90(5): 432-439 (IF 2.8) [PubMed] [HTML] [PDF]
Bücker R, Krug SM, Rosenthal R, Günzel D, Fromm A, Zeitz M, Chakraborty T, Fromm M, Epple HJ, Schulzke JD (2011) Aerolysin from Aeromonas hydrophila perturbs tight junction integrity and cell lesion repair in intestinal epithelial HT-29/B6 cells. J. Infect. Dis. 204 (8): 1283-1292 (IF 6.4) [PubMed] [HTML] [PDF]
Hering NA*, Andres S* (*shared first authorship), Fromm A, van Tol EA, Amasheh M, Mankertz J, Fromm M, Schulzke JD (2011)
Hering NA, Richter JF, Krug SM, Günzel D, Fromm A, Bohn E, Rosenthal R, Bücker R, Fromm M, Troeger H, Schulzke JD (2011) Yersinia enterocolitica induces epithelial barrier dysfunction through regional tight junction changes in colonic HT-29/B6 cell monolayers. Lab. Invest. 91(2): 310-324 (IF 3.6) [PubMed] [HTML] [PDF] [Supplement DOC]
Schulzke JD*, Andres S*, Amasheh M* (*shared first authorship), Fromm A, Günzel D (2011) Anti-diarrheal mechanism of the traditional remedy Uzara via reduction of active chloride secretion. PLoS One 6(3): e18107 (print 1-9) (IF 4.1) [PubMed] [HTML] [PDF]
2010
Amasheh M, Fromm A, Krug SM, Amasheh S, Andres S, Zeitz M, Fromm M, Schulzke JD (2010) TNFa-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, pAkt, and NFkB signaling. J. Cell Sci. 123(23): 4145-4155 (IF 6.3) [PubMed] [HTML] [PDF] [Supplements]
Schulzke JD*, Pfaffenbach S* (*shared first authorship), Fromm A, Epple HJ, Troeger H*, Fromm M* (*shared last authorship) (2010) PGI2 sensory input into the ENS during distension-induced colonic chloride secretion in rat colon. Acta Physiol. 199(3): 305-316 (IF 3.2) [PubMed] [HTML] [PDF]
2009
Amasheh M, Grotjohann I, Amasheh S, Fromm A, Söderholm JD, Zeitz M, Fromm M, Schulzke JD (2009) Regulation of mucosal structure and barrier function in rat colon exposed to tumor necrosis factor alpha and interferon gamma in vitro: A novel model for studying the pathomechanisms of inflammatory bowel disease cytokines. Scand. J. Gastroent. 44: 1226-1235 [PubMed] [HTML] [PDF]
Bergann T, Plöger S, Fromm A, Zeissig S, Borden SA, Fromm M, Schulzke JD (2009) A colonic mineralocorticoid receptor cell model expressing epithelial Na+ channels. Biochem. Biophys. Res. Comm. 381(2): 280-285 [PubMed] [HTML] [PDF]
Bergann T, Zeissig S, Fromm A, Richter JF, Fromm M, Schulzke JD (2009) Glucocorticoid and tumor necrosis factor-alpha synergize to induce absorption by the epithelial sodium channel in the colon. Gastroenterology 136(3): 933-942 [PubMed] [HTML] [PDF]
Mankertz J*, Amasheh M* (*shared first authorship), Krug SM, Fromm A, Amasheh S, Hillenbrand B, Tavalali S, Fromm M, Schulzke JD (2009) TNFalpha up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling. Cell Tiss. Res. 336(1): 67-77 [PubMed] [HTML] [PDF]
Ziera T, Irlbacher H, Fromm A, Latouche C, Krug SM, Fromm M, Jaisser F, Borden SA (2009) Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel. FASEB J. 23(11): 3936-3946 [PubMed] [HTML] [PDF]
Schulzke JD*, Ploeger S* (*shared first authorship), Amasheh M, Fromm A, Zeissig S, Troeger H, Richter JF, Bojarski C, Schumann M, Fromm M (2009) Epithelial tight junctions in intestinal inflammation. Ann. N.Y. Acad. Sci. 1165: 294-300 [PubMed] [HTML] [PDF] (Review)
2008
Heller F, Fromm A, Gitter AH, Mankertz J, Schulzke JD (2008) Epithelial apoptosis is a prominent feature of the epithelial barrier disturbance in intestinal inflammation: effect of pro-inflammatory interleukin-13 on epithelial cell function. Mucosal Immun. 1: S58-S61 [PubMed] [HTML] [PDF]
Zeissig S, Bergann T, Fromm A, Bojarski C, Heller F, Guenther U, Zeitz M, Fromm M, Schulzke JD (2008) Altered ENaC expression leads to impaired sodium absorption in the non-inflamed intestine in Crohn's disease. Gastroenterology 134(5): 1436-1447 [PubMed] [HTML] [PDF]
2007
Zeissig S, Fromm A, Mankertz J, Weiske J, Zeitz M, Fromm M, Schulzke JD (2007) Butyrate induces intestinal sodium absorption via Sp3-mediated transcriptional up-regulation of epithelial sodium channels. Gastroenterology 132(1): 236-248 [PubMed] [HTML+links] [PDF]
2006
Zeissig S, Fromm A, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2006) Restoration of ENaC expression by glucocorticoid receptor transfection in human HT-29/B6 colon cells. Biochem. Biophys. Res. Commun. 344(4): 1065-1070 [PubMed] [HTML] [PDF]
