 Institute of Clinical Physiology |
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Institute of Clinical Physiology |
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PubMed list |
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2013
Krug SM, Amasheh M, Dittmann I, Christoffel I, Fromm M, Amasheh S (2013) Sodium caprate as an enhancer of macromolecule permeation across tricellular tight junctions of intestinal cells. Biomaterials 34(1): 275-282
2012
Juric M, Xiao F, Amasheh S, May O, Wahl K, Bantel H, Manns MP, Seidler U, Bachmann O (2012) Increased epithelial permeability is the primary cause for bicarbonate loss in inflamed murine colon. Inflamm. Bowel Dis. ###: ###-### (IF 4.9) [06.09.12 Accepted]
Amasheh M, Luettig J, Amasheh S, Zeitz M, Fromm M, Schulzke JD (2012) Effects of quercetin on the colonic cell culture model HT-29/B6 and rat intestine in vitro. Ann. N.Y. Acad. Sci.
Hackel D, Krug SM, Sauer RS, Mousa SA, Böcker A, Pflücke D, Wrede EJ, Kistner K, Hoffmann T, Niedermirtl B, Sommer C, Bloch L, Huber O, Blasig IE, Amasheh S, Reeh PW, Fromm M, Brack A, Rittner HL (2012) Transient opening of the perineurial barrier for analgesic drug delivery. Proc. Natl. Acad. Sci. USA 109(29): E2018-E2027
Krug SM, Günzel D, Conrad MP, Rosenthal R, Fromm A, Amasheh S, Schulzke JD, Fromm M (2012) Claudin-17 forms tight junction channels with distinct anion selectivity. Cell. Mol. Life Sci. 69(16): 2765-2778
Markov AG, Kruglova NM, Fomina YA, Fromm M, Amasheh S (2012) Altered expression of tight junction proteins in mammary epithelium after discontinued suckling in mice. Pflügers Arch. 463(2): 391-398 (IF 4.5) [PubMed] [HTML] [PDF]
Rittner HL, Amasheh S, Moshourab R, Hackel D, Yamdeu RS, Fromm M, Stein C, Brack A (2012) Modulation of tight junction proteins in the perineurium to facilitate peripheral opioid analgesia. Anesthesiology 116(6): 1323-1334
Rosenthal R*, Günzel D* (*shared first authorship), Finger C, Krug SM, Richter JF, Schulzke JD, Fromm M, Amasheh S (2012) The effect of chitosan on transcellular and paracellular mechanisms in the intestinal epithelial barrier. Biomaterials 33(9): 2791-2800 (IF 7.4) [PubMed] [HTML] [PDF] [Supplement]
Rubelt MS, Amasheh S, Grobosch T, Stein C (2012) Liquid chromatography-tandem mass spectrometry for analysis of intestinal permeability of loperamide in physiological buffer. PLoS One 7(11): e48502 (print pages 1-8) (IF 4.1)
Reviews
Krug SM, Günzel D, Conrad MP, Lee IM, Amasheh S, Fromm M, Yu ASL (2012) Charge-selective claudin channels. Ann. N.Y. Acad. Sci. 1257: 20-28
Rosenthal R, Heydt MS, Amasheh M, Stein C, Fromm M, Amasheh S (2012) Analysis of absorption enhancers in epithelial cell models. Ann. N.Y. Acad. Sci. 1258: 86-92
2011
Markov AG,
Voronkova MA, Volgin GN, Yablonsky PK, Fromm M, Amasheh S (2011)
Tight junction proteins contribute to barrier properties in human pleura.
Resp. Physiol. Neurobiol.
175(3): 331-335 (IF 2.2)
[PubMed] [HTML]
[PDF] Reviews
Amasheh S, Fromm M, Günzel D (2011) Claudins of intestine and nephron - a correlation of molecular tight junction structure and barrier function. Acta Physiol. 201(1): 133-140 (IF 3.1) [PubMed] [HTML] [PDF] (Review)
Markov AG, Amasheh S (2011) Barrier properties and tight junction protein expression along the longitudinal axis of rat intestine. Russ. J. Physiol. (Ross. Fiziol. Zh. Im. I. M. Sechenova) 97(10): 1066-1083 [PubMed]
2010
Amasheh M, Fromm A, Krug SM, Amasheh S, Andres S, Zeitz M, Fromm M, Schulzke JD (2010) TNFa-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, pAkt, and NFkB signaling. J. Cell Sci. 123(23): 4145-4155 (IF 6.1) [PubMed] [HTML] [PDF] [Supplements]
Becker S*, Wandel E* (*shared first authorship), Wobus M, Schneider R, Amasheh S, Sittig D, Kerner C, Naumann R, Hamann J, Aust G (2010) Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions. Plos One 5(1): e8507 (print 1-11) (IF 4.4) [PubMed] [HTML] [PDF]
Markov AG*, Veshnyakova A* (*shared first authorship), Fromm M, Amasheh M, Amasheh S (2010) Segmental expression of claudin proteins correlates with tight junction barrier properties in rat intestine. J. Comp. Physiol. B 180(4): 591-598 (IF 2.4) [PubMed] [HTML] [PDF]
Milatz S, Krug SM, Rosenthal R, Günzel D, Müller D, Schulzke JD, Amasheh S*, Fromm M* (*shared last authorship) (2010) Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes. Biochim. Biophys. Acta Biomembr. 1798: 2048-2057 (IF 4.6) [PubMed] [HTML] [PDF]
Rosenthal R, Milatz S, Krug SM,
Oelrich B, Schulzke JD, Amasheh S, Günzel D, Fromm M (2010) Claudin-2,
a component of the tight junction, forms a paracellular water channel.
J. Cell Sci. 123(11): 1913-1921
(IF 6.1)
[PubMed] [HTML]
[PDF]
[Supplement]
Review
Bücker R, Schumann M, Amasheh S, Schulzke JD (2010) Claudins in intestinal function and disease. Curr. Top. Membr. 65: 195-227 [Directory] [HTML] [PDF] (review / book chapter)
2009
Amasheh S, Dullat S, Fromm M, Schulzke JD, Buhr HJ, Kroesen AJ (2009) Inflamed pouch mucosa possesses altered tight junctions indicating recurrence of inflammatory bowel disease. Int. J. Colorectal Dis. 24(10): 1149-1156 [PubMed] [HTML] [PDF]
Amasheh S*, Milatz S* (*shared first authorship), Krug SM, Bergs M, Amasheh M, Schulzke JD, Fromm M (2009) Na+ absorption defends from paracellular back-leakage by claudin-8 upregulation. Biochem. Biophys. Res. Comm. 378(1): 45-50 [PubMed] [HTML] [PDF]
Amasheh M, Andres S, Amasheh S, Fromm M, Schulzke JD (2009) Barrier effects of nutritional factors. Ann. N.Y. Acad. Sci. 1165: 267-273 [PubMed] [HTML] [PDF]
Amasheh M, Grotjohann I, Amasheh S, Fromm A, Söderholm JD, Zeitz M, Fromm M, Schulzke JD (2009) Regulation of mucosal structure and barrier function in rat colon exposed to tumor necrosis factor alpha and interferon gamma in vitro: A novel model for studying the pathomechanisms of inflammatory bowel disease cytokines. Scand. J. Gastroent. 44: 1226-1235 [PubMed] [HTML] [PDF]
Amasheh M, Grotjohann I, Amasheh S, Fromm A, Söderholm JD, Zeitz M, Fromm M, Schulzke JD (2009) Regulation of mucosal structure and barrier function in rat colon in vitro exposed to TNFalpha and IFNgamma: a novel model for studying IBD pathomechanisms. Scand. J. Gastroent. [16.06.09: accepted]
Günzel D, Amasheh S, Pfaffenbach S, Richter JF, Kausalya PJ, Hunziker W, Fromm M (2009) Claudin-16 affects transcellular Cl- secretion in MDCK cells. J. Physiol. 587(15): 3777-3793 [PubMed] [HTML] [PDF] [Supplement]
Krug SM, Amasheh S, Richter JF, Milatz S, Günzel D, Westphal JK, Huber O, Schulzke JD, Fromm M (2009) Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability. Mol. Biol. Cell 20: 3713-3724 [PubMed] [HTML] [PDF] [Supplement text] [Supplement video]
Mankertz J*, Amasheh M* (*shared
first authorship), Krug SM, Fromm A, Amasheh S, Hillenbrand B, Tavalali
S, Fromm M, Schulzke JD (2009) TNFalpha up-regulates claudin-2 expression in
epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling.
Cell Tiss. Res. 336(1): 67-77 [PubMed]
[HTML]
[PDF] Reviews
Amasheh S, Milatz S, Krug SM, Markov AG, Günzel D, Amasheh M, Fromm M (2009) Tight junction proteins as channel formers and barrier builders: claudin-2, -5, and -8. Ann. N.Y. Acad. Sci. 1165: 211-219 [PubMed] [HTML] [PDF]
Günzel D, Haisch L, Pfaffenbach S, Krug SM, Milatz S, Amasheh S, Hunziker W, Müller D (2009) Claudin function in the thick ascending limb of Henle's loop. Ann. N.Y. Acad. Sci. 1165: 152-162 [PubMed] [HTML] [PDF]
2008
Amasheh M, Schlichter S, Amasheh S, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2008) Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells. J. Nutr. 138(6):1067-1073 [PubMed] [HTML] [PDF]
Thumfart J, Jung S, Amasheh S, Krämer S, Peters H, Sommer K, Biber J, Murer H, Meij I, Querfeld U, Wagner CA, Müller D (2008) Magnesium stimulates renal phosphate reabsorption. Am. J. Physiol. Renal Physiol. 295(4): F1126-F1133 [PubMed] [Full paper HTML] [PDF]
2006
Kausalya PJ*, Amasheh S* (*shared first authorship, p 890), Günzel D, Wurps H, Müller D, Fromm M, Hunziker W (2006) Disease-associated mutations affect intracellular traffic and paracellular Mg2+ transport function of claudin-16. J. Clin. Invest. 116(4): 878-891 [PubMed] [HTML] [PDF]
Schierack P, Nordhoff M, Pollmann
M, Weyrauch KD, Amasheh S, Lodemann U, Jores J, Tachu B, Kleta S,
Blikslager A, Tedin K, Wieler LH (2006) Characterization of a porcine
intestinal epithelial cell line for in vitro studies of microbial pathogenesis
in swine. Histochem. Cell Biol.
125: 293-305 [PubMed]
[HTML]
[PDF] Review
Markov AG, Shadrin LV, Veshnyakova A, Amasheh S, Fromm M (2006) The tight junction proteins claudin-2 and -16 expression in mammary epithelium of mice. Russ. J. Physiol. (Ross. Fiziol. Zh. Im. I. M. Sechenova) 92(11): 1382-1386 [PubMed listing]
2005
Amasheh S, Schmidt T, Mahn M, Florian P, Mankertz J, Tavalali S, Gitter AH, Schulzke JD, Fromm M (2005) Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells. Cell Tissue Res. 321(1): 89-96 [PubMed] [HTML] [PDF]
Schulzke JD, Gitter AH, Mankertz J, Spiegel S, Seidler U, Amasheh S, Saitou M, Tsukita S, Fromm M (2005) Epithelial transport and barrier function in occludin-deficient mice. Biochim. Biophys. Acta - Biomembranes 1669(1): 34-42 [PubMed] [HTML] [PDF]
2004
Amasheh S, Barmeyer C, Koch CS, Tavalali S, Mankertz J, Epple HJ, Gehring MM, Florian P, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD (2004) Cytokine-dependent transcriptional down-regulation of epithelial sodium channel (ENaC) in ulcerative colitis. Gastroenterology 126: 1711-1720 [PubMed] [HTML] [PDF]
Barmeyer C*, Amasheh S* (*shared first authorship), Tavalali S, Mankertz J, Zeitz M, Fromm M, Schulzke JD (2004) IL-1beta and TNFalpha regulate sodium absorption in rat distal colon. Biochem. Biophys. Res. Comm. 317: 500-507 [PubMed] [HTML] [PDF]
2002 - 2003
Amasheh S, Meiri N, Gitter AH, Schöneberg T, Mankertz J, Schulzke JD, Fromm M (2002) Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells. J. Cell Sci. 115(24): 4969-4976 [PubMed] [HTML] [PDF]
Florian P, Amasheh S, Lessidrensky M, Todt I, Bloedow A, Ernst A, Fromm M, Gitter AH (2003) Claudins in the tight junctions of stria vascularis marginal cells. Biochem. Biophys. Res. Comm. 304: 5-10 [PubMed] [HTML] [PDF]
Tebbe B, Mankertz J, Schwarz C, Amasheh S, Fromm M, Schultz-Ehrenburg U, Sánchez Ruderisch H, Schulzke JD, Orfanos CE (2002) Tight junction proteins: A novel class of integral membrane proteins. Expression in human epidermis and HaCaT keratinocytes. Arch. Dermatol. Res. 294: 14-18 [PubMed] [HTML] [PDF]
1999 - 2000
Amasheh S, Weber W (1999) Further characteristics of the Ca2+-inactivated Cl- channel in Xenopus laevis oocytes. J. Membr. Biol. 172: 169-179 [PubMed summary] [PDF]
Epple HJ, Amasheh S,
Mankertz J, Goltz M, Schulzke JD, Fromm M (2000) Early aldosterone effect in
distal colon by transcriptional regulation of ENaC subunits.
Am. J. Physiol. 278(5): G718-G724 [PubMed
summary] [PDF] Reviews
Amasheh S, Epple HJ, Mankertz J, Detjen K, Goltz M, Schulzke JD, Fromm M (2000) Differential regulation of ENaC by aldosterone in rat early and late distal colon. Ann. N.Y. Acad. Sci. 915: 92-94 [PubMed reference] [Full text]
1996 - 1998
Doering F, Will J, Amasheh S, Clauss W, Ahlbrecht H, Daniel H (1998) Minimal molecular determinants of substrates for recognition by the intestinal peptide transporter. J. Biol. Chem. 273: 23211-23218 [PubMed summary]
Doering F, Walter J, Foecking M, Amasheh S, Daniel H (1998) The aminoterminal region of the renal peptide transporter PepT2 determines its high substrate affinity. Nova Acta Leopoldina 78: 269-274
Doering F, Walter J, Will J, Foecking M, Amasheh S, Clauss W, Daniel H (1998) Delta-aminolevulinic acid transport by intestinal and renal peptide transporters and its physiological and clinical implications. J. Clin. Invest. 101: 2761-2767 [PubMed summary]
Amasheh S, Weber WM, Wenzel U, Clauss W, Daniel H (1997) Electrophysiological analysis of a mammalian renal peptide transporter expressed in Xenopus laevis oocytes. J. Physiol. (Lond.) 504: 169-174 [PubMed summary]
Amasheh S, Wenzel U, Boll M, Dorn D, Weber WM, Clauss W, Daniel H (1997) Transport of charged dipeptides by the intestinal H+/peptide symporter PepT1 expressed in Xenopus laevis oocytes. J. Membr. Biol. 155: 247-256 [PubMed summary]
Reifarth FW, Amasheh S, Clauss W, Weber WM (1997) The Ca2+-inactivated Cl- channel at work: selectivity, blocker kinetics and transport visualisation. J. Membr. Biol. 155: 95-104 [PubMed summary]
Doering F, Dorn D, Bachfischer U, Amasheh S, Herget M, Daniel H (1996) Functional analysis of a chimeric mammalian peptide transporter derived from the intestinal and renal isoforms. J. Physiol. (Lond.) 497: 773-779 [PubMed summary]
