Institute of Clinical Physiology
Chair:  Prof. Dr. Michael Fromm

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Our profile
  

Main research topics of the Institute of Clinical Physiology are the tight junction and membrane channel molecules of the "intelligent borders of the body", the epithelia.
  

We perform basic research as well as research related to diseases of the intestines, kidneys, and eyes.
  

Methods are molecular biological, electrophysiological, biophysical, laser scanning fluorescence microscopical, and freeze fracture EM.

  

Our main grants are from the German Reseach Foundation (Deutsche Forschungsgemeinschaft): Research Unit FOR 721 (Coordinator and 4 projects), Collaborative Research Center SFB 852 (1 project), and Personal Research Grants.
  

We perform numerous joint research projects with colleagues from clinical departments, some of which are fulltime in our lab (Fulltime associates*).
 

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Research topics     Clinical
Physiology		   Lab cooperation (* = Fulltime associates)
Tight Junction:
claudin-1 to -24,
occludin, tricellulin

DFG Research Unit 721

   Michael Fromm,
Dorothee Günzel,
Salah Amasheh,
Rita Rosenthal,
Susanne Krug,
Susanne Milatz,
Marcel Conrad		   Gastroenterology, Div. Nutritional Med.: Joerg Schulzke,
Maren Amasheh*, Nina Hering*
Gastroenterology: Michael Schumann*
Neurosurgery: Kinga Blecharz
Univ. partnership Berlin - St. Petersburg:
Alexander Markov
Nutrition and
intestinal barrier

DFG SFB 852, project B2

   Michael Fromm,
Dorothee Günzel,
Silke Zakrzewski		   Gastroenterology, Div. Nutritional Med.: Joerg Schulzke,
Maren Amasheh*, Dana Kuntzsch*, Julia Luettig*
Gastroenterology: Michael Schumann*
Inflammatory
bowel diseases
cytokines & interleukins		   Michael Fromm,
Salah Amasheh,
Susanne Krug		   Gastroenterology, Div. Nutritional Med.: Joerg Schulzke,
Maren Amasheh*, Lena John*
Gastroenterology: Michael Schumann*, Christian Barmeyer
Christian Bojarski
Veterinary Physiol. FU Berlin: Svenja Ploeger
Claudins in renal epithelia   Dorothee Günzel,
Susanne Milatz		  
Macromolecular
permeation

Absorption enhancers

   Michael Fromm,
Jan Richter,
Susanne Krug

Salah Amasheh,
Rita Rosenthal

   Gastroenterology, Div. Nutritional Med.: Joerg Schulzke
Gastroenterology: Michael Schumann*

Anesthesiology:
 Miriam Heydt
Intestinal Infectiology   Michael Fromm,
Dorothee Günzel,
Silke Zakrzewski		   Gastroenterology, Div. Nutritional Med.:
 Joerg Schulzke, Roland Bücker*, Nina Hering*,
Gastroenterology: Hans-Joerg Epple, Hanno Troeger
Epithelial sodium channel
 (ENaC)		   Michael Fromm,
Salah Amasheh,
Susanne Milatz		   Gastroenterology, Div. Nutritional Med.: Joerg Schulzke,
Petra Dames*
Physiology of the eye   Rita Rosenthal  
Method: Impedance
spectroscopy		   Dorothee Günzel,
Susanne Krug		  
Method: Freeze fracture
electron microscopy		   Susanne Krug,
In-Fah Lee		  

Overview:  Staff   Research topics   News & Events 
Doctoral fellows    Alumni doctoral fellows  

  Publications:  The Institute   Fromm   Günzel 
S. Amasheh   Rosenthal   Krug   Milatz 

 
History

The institute was founded in 1969 and chaired until 1995 by Prof. Klaus Hierholzer († 11.02.2007),
followed by Prof. Michael Wiederholt. Other retired professors are Prof. Ulrich Hegel and Prof. Hans Ebel.
Since 2002 the institute is chaired by Prof. Michael Fromm.
 

Address
The main building of the Campus Benjamin Franklin (CBF)
of the Charité - Universitaetsmedizin Berlin, a joint institution of the
Freie Universitaet Berlin and the Humboldt-Universitaet Berlin		    University Hospital Benjamin Franklin (UKBF) pics
Postal address:  Institute of Clinical Physiology
Charité, Campus Benjamin Franklin
12200 Berlin
Germany
Physical address: Hindenburgdamm 30
12203 Berlin (Steglitz)
  Street Map    GoogleEarth-Map
Public transportation: Subway (U-Bahn "U9") or local train (S-Bahn "S1") 
to "Rathaus Steglitz", then change for bus 285 or M85, 
exit bus stop "Universitätsklinikum Benjamin Franklin"  Local map
Fares: Single ticket for 2 hrs, unlimited changes: "AB" 2.30 Euro
or, ONLY bus 285 or M85 from Rathaus Steglitz: "Kurzstrecke" 1.40 Euro  
Location within the hospital: Elevator No. 17 or 18,  5th floor,  turn right
   
Chair:
 		 Prof. Dr. med. Michael Fromm
michael.fromm@charite.de
Representative of the German Research Foundation
(DFG) at the Charité:		   Hints & requirements for applying at the DFG
Phone direct:
Phone M.F. via secretary:		 +49 30 8445 2787
+49 30 8445 2535 (9:30–16:30, Fri –15:30)
Secretary:
Phone of secretary:		 Elisabeth Schultze
+49 30 8445 2534 (9:30–16:30, Fri –15:30)
elisabeth.schultze@charite.de
FAX: +49 30 8445-4239

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