Publications
Requests for electronic reprints (pdf) of any of the following articles may be addressed to the
authors.
2008
Fabian H, Huser H, Narzi D, Misselwitz R, Loll B, Ziegler A, Böckmann RA, Uchanska-Ziegler B, Naumann D.
HLA-B27 subtypes differentially associated with disease exhibit conformational differences in solution.
J Mol Biol.376;3, 798-810
2007
Kumar P, Vahedi-Faridi A, Merino E, Lopez de Castro JA, Volz A, Ziegler A, Saenger W, Uchanska-Ziegler B.
Expression, purification and preliminary X-ray crystallographic analysis of the human major histocompatibility antigen HLA-B*1402 in complex with a viral peptide and with a self-peptide.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 1;63, 631-4
Ziegler A, Coulie PG, Uchanska-Ziegler B.
Monoclonal and recombinant antibodies with T cell receptor-like reactivity.
Recent Results Cancer Res. 176, 229-41.
Uchanska-Ziegler B, Ziegler A.
On the reactivity of monoclonal antibodies specific for different forms of HLA class I molecules.
Rheumatology (Oxford). 46(3) 555-6; author reply 556-7.
Winkler, K., Winter, A., Rueckert C., Uchanska-Ziegler, B., and Alexiev, U.
Natural MHC class I polymorphism controls the pathway of peptide dissociation from HLA-B27 complexes
Biophys. J. Published ahead of print on June 15, (in press) (2007)
2006
Volz A. and Radeloff B.
Detecting the unusual: natural killer cells.
Prog Nucleic Acid Re 81: 473-541
Ziegler A, Uchanska-Ziegler B.
Rheumatoid arthritis etiology and HLA-linked odorant receptor gene polymorphisms: Comment on the article by Klareskog et al.
Arthritis Rheum. 54 (8):2705-2706
Laun K, Coggill P, Palmer S, Sims S, Ning Z, Ragoussis J, Volpi E, Wilson N, Beck S, Ziegler A, Volz A.
The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like loci.
PLoS Genet. 2:e73
Rückert C, Fiorillo MT, Loll B, Moretti R, Biesiadka J, Saenger W, Ziegler A, Sorrentino R, Uchanska-Ziegler B.
Conformational dimorphism of self-peptides and molecular mimicry in a disease-associated HLA-B27 subtype.
J Biol Chem. 281:2306-16
Rölleke U., Flügge G., Plehm S., Schlumbohm C., Armstrong V.W., Dressel R., Uchanska-Ziegler B., Ziegler A., Fuchs E., Czéh B., Walter L.
Differential expression of major histocompatibility complex class I molecules in the brain of a New World monkey, the common marmoset (Callithrix jacchus).
J Neuroimmunol: 176: 39-50
Uchanska-Ziegler, B., Alexiev, U., Hillig, R., Hülsmeyer, M., Pöhlmann, T., Saenger, W., Volz, A., and Ziegler, A.
X-ray crystallography and dynamic studies of HLA-B*2705 and B*2709 molecules complexed with the same peptide.
In HLA 2004: Immunobiology of the Human MHC. Proceedings of the 13th International Histocompatibility Workshop and Congress.
(Dupont, B. and Hansen, J.A., eds.), Volume I & II, IHWG Press, Seattle, WA, (ISBN 0-945278-03-9) Vol. I pp.138-147
Ziegler, A., Dohr, G., Kentenich, H., and Uchanska-Ziegler, B.
Self nonself discrimination and reproductive performance.
HLA 2004: Immunobiology of the Human MHC. Proceedings of the 13th International Histocompatibility Workshop and Congress.
(Dupont, B. and Hansen, J.A., eds.), Volume I & II, IHWG Press, Seattle, WA, (ISBN 0-945278-03-9) Vol. I pp.1534-1538
Ziegler, A., Beck, S., Ehlers, A., Younger, R. and Volz, A.
Testicular transcripts of HLA-linked olfactory receptor genes exhibit unorthodox features.
HLA 2004: Immunobiology of the Human MHC. Proceedings of the 13th International Histocompatibility Workshop and Congress.
. (Dupont, B. and Hansen, J.A., eds.), Volume I & II, IHWG Press, Seattle, WA, (ISBN 0-945278-03-9) Vol II pp.42-46
2005
Zawacka A, Loll B, Biesiadka J, Saenger W, Uchanska-Ziegler B, Ziegler A.
X-ray diffraction analysis of crystals from the human major histocompatibility antigen HLA-B*2706 in complex with a viral peptide and with a self-peptide.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 61:1097-9.
Ziegler A, Kentenich H, Uchanska-Ziegler B.
Female choice and the MHC
Trends Immunol. 26:496-502
Ziegler A, Loll B, Biesiadka J, Saenger W, Kellermann T, Misselwitz R, Uchanska-Ziegler B.
A cartilage-derived self peptide presented by HLA-B27 molecules?
Arthritis Rheum. 52:2581-2582
Radeloff, B., Nagler, L., Zirra, M., Ziegler, A., & Volz, A.
Specific amplification of cDNA ends (SPACE): A new tool for the analysis of rare transcripts and its application for the promoter analysis of killer cell receptor genes
DNA Sequence, 16: 44-52
Blaschitz A, Juch H, Volz A, Hutter H, Daxboeck C, Desoye G, Dohr G.
The soluble pool of HLA-G produced by human trophoblasts does not include detectable levels of the intron 4-containing HLA-G5 and HLA-G6 isoforms.
Mol Hum Reprod. 11:699-710
Blaschitz A, Juch H, Volz A, Hutter H, Dohr G.
Soluble HLA-G, the discussion is going on!
Mol Hum Reprod. 11:723-7
Huber M, Siegenthaler G, Mirancea N, Marenholz I, Nizetic D, Breitkreutz D, Mischke D, Hohl D.
Isolation and characterization of human repetin, a member of the fused gene family of the epidermal differentiation complex.
J Invest Dermatol. 124: 998-1007
Bernhard Loll, Anna Zawacka, Jacek Biesiadka, Christine Rückert, Armin Volz, Wolfram Saenger, Barbara Uchanska-Ziegler and Andreas Ziegler
Purification, crystallization and preliminary X-ray diffraction analysis of the human major histocompatibility antigen HLA-B*2703 complexed with a viral peptide and with a self-peptide
Acta Crystallographica Section F61, 372-374
Fiorillo, M.T., Kozerski, C., Hülsmeyer, M., Sorrentino, R., Saenger, W., Ziegler, A., and Uchanska-Ziegler, B.
Allele-dependent similarity between viral and self-peptide presentation by HLA-B27 subtypes.
J. Biol. Chem. 280: 2962-2971
Hülsmeyer M, Welfle K, Pohlmann T, Misselwitz R, Alexiev U, Welfle H, Saenger W, Uchanska-Ziegler B, Ziegler A.
Thermodynamic and structural equivalence of two HLA-B27 subtypes complexed with a self-peptide.
J Mol Biol. 346:1367-1379
Hülsmeyer, M., Chames, P., Hillig, R.C., Stanfield, R.L., Held, G., Coulie, P.G., Alings, C., Wille, G., Saenger, W., Uchanska-Ziegler, B., Hoogenboom, H.R., and Ziegler, A.
A major histocompatibility complex:peptide-restricted antibody and T cell receptor molecules recognize their target by distinct binding modes. Crystal structure of human leukocyte antigen (HLA)-A1:MAGE-A1 in complex with Fab-Hyb3.
J. Biol. Chem. 280:2972-2980
Loll B, Zawacka A, Biesiadka J, Petter C, Ruckert C, Saenger W, Uchanska-Ziegler B, Ziegler A.
Preliminary X-ray diffraction analysis of crystals from the recombinantly expressed human major histocompatibility antigen HLA-B*2704 in complex with a viral peptide and with a self-peptide.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 61:939-41.
2004
Horton, R., Wilming, L., Rand, V., Lovering, R.C., Bruford, E.A., Khodiyar, V.K., Lush, M.J., Povey, S., Talbot, C.C., Wright, M.W., Wain, H.M.. Trowsdale, J., Ziegler, A., and Beck, S.
Gene map of the extended human MHC.
Nat. Rev. Genet. 5, 889-899 (2004)
Pohlmann T, Bockmann RA, Grubmuller H, Uchanska-Ziegler B, Ziegler A, Alexiev U.
Differential peptide dynamics is linked to major histocompatibility complex polymorphism.
J Biol Chem. 279: 28197-201 (2004)
Hülsmeyer M, Fiorillo MT, Bettosini F, Sorrentino R, Saenger W, Ziegler A, Uchanska-Ziegler B.
Dual, HLA-B27 Subtype-dependent Conformation of a Self-peptide.
J Exp Med. 199: 271-281 (2004)
Hillig RC, Hülsmeyer M, Saenger W, Welfle K, Misselwitz R, Welfle H, Kozerski C, Volz A, Uchanska-Ziegler B, Ziegler A.
Thermodynamic and structural analysis of peptide- and allele-dependent properties of two HLA-B27 subtypes exhibiting differential disease association.
J Biol Chem. 279: 652-63 (2004)
2003
Ziegler A.
Moleküle des MHC und olfaktorische Rezeptoren: Mögliche Bedeutung im Rahmen der Reproduktion
J Fertil Reprod 13): 14-18 (2003)
Amadou C, Younger RM, Sims S, Matthews LH, Rogers J, Kumanovics A, Ziegler A, Beck S, Lindahl KF.
Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex.
Hum Mol Genet. 2003 Nov 15;12(22):3025-40. Epub 2003 Sep 23
Uchanska-Ziegler B; Ziegler A
Response to Xie and Yi: Ankylosing spondylitis: a beta(2)m-deposition disease?
Trends Immunol. 24:229-230, (2003)
Radeloff B, Laun K, Zirra M, Volz A.
Killer immunoglobulin-like receptor expression on single cells: a cautionary note.
Immunology. 110 421-6 (2003)
Uchanska-Ziegler B, Ziegler A.
Ankylosing spondylitis: a beta2m-deposition disease?
Trends Immunol. 24: 73-6 (2003)
Volz A, Ehlers A, Younger R, Forbes S, Trowsdale J, Schnorr D, Beck S, Ziegler A.
Complex transcription and splicing of odorant receptor genes.
J Biol Chem. 2003 278(22):19691-701.
Dong L, Hülsmeyer M, Dürkop H, Hansen HP, Schneider-Mergener J, Ziegler A, Uchanska-Ziegler B.
Human CD30: Structural implications from epitope mapping and modeling studies
J Mol Recognit. 2003 Jan-Feb;16(1):28-36
Krauss, J., Förster, H.H., Uchanska-Ziegler, B. and Ziegler, A
Chimerization of a monoclonal antibody for treating Hodgkinxs lymphoma.
Methods Mol. Biol. 207, 63-79 (2003)
2002
Ziegler A, Dohr G, Uchanska-Ziegler B..
Possible roles for products of polymorphic MHC and linked olfactory receptor genes during selection processes in reproduction
Am J Reprod Immunol. 48: 34-42 (2002)
Hülsmeyer M, Hillig RC, Volz A, Rühl M, Schröder W, Saenger W, Ziegler A, Uchanska-Ziegler B.
HLA-B27 subtypes differentially associated with disease exhibit subtle structural alterations
J Biol Chem. 277: 47844-53 (2002)
Drysdale J, Arosio P, Invernizzi R, Cazzola M, Volz A, Corsi B, Biasiotto G, Levi S..
Mitochondrial ferritin: a new player in iron metabolism
Blood Cells Mol Dis. 29: 376-83 (2002)
Meza-Zepeda LA, Forus A, Lygren B, Dahlberg AB, Godager LH, South AP, Marenholz I, Lioumi M, Florenes VA, Maelandsmo GM, Serra M, Mischke D, Nizetic D, Ragoussis J, Tarkkanen M, Nesland JM, Knuutila S, Myklebost O. Related Articles, Links.
Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21
Oncogene. 2002 Mar 28;21(14):2261-9.
Dangoria, N.S., DeLay, M., Kingsbury, D.J., Mear, J.P., Uchanska-Ziegler, B., Ziegler, A. and Colbert, R.A.
HLA-B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum.
J. Biol. Chem. 277, 23459-23468 (2002)
Wende, H., Ziegler, A. and Volz, A.
Genomic organization of the ILT11 gene, a novel member of the Leukocyte Receptor Cluster.
In Activating and inhibitory immunoglobulin-like receptors (Cooper, M.D., Takai, T. and Ravetch, J.V., eds.), pp. 17-24, Springer Verlag, Tokyo (2002)
Hemmann, S., Ziegler, A. and Uchanska-Ziegler, B.
Expression of the cysteine-rich extracellular domain of CD30 in Drosophila melanogaster S2 cells and selection of CD30-specific human single-chain Fv antibodies from a phage display library.
In Leukocyte Typing VII (Mason, D. et al., eds.), pp. 463-466 (2002)
2001
Volz A, Wende H, Laun K, Ziegler A.
Genesis of the ILT/LIR/MIR clusters within the human leukocyte receptor complex.
Immunol Rev. 2001 Jun;181:39-51.
Younger RM, Amadou C, Bethel G, Ehlers A, Lindahl KF, Forbes S, Horton R, Milne S, Mungall AJ, Trowsdale J, Volz A, Ziegler A, Beck S.
Characterization of clustered MHC-linked olfactory receptor genes in human and mouse.
Genome Res. 2001 Apr;11(4):519-30.
Levi S, Corsi B, Bosisio M, Invernizzi R, Volz A, Sanford D, Arosio P, Drysdale J.
A human mitochondrial ferritin encoded by an intronless gene.
J Biol Chem. 2001 Jul 6;276(27):24437-40.
Hillig RC, Coulie PG, Stroobant V, Saenger W, Ziegler A, Hulsmeyer M.
High-resolution structure of HLA-A*0201 in complex with a tumour-specific antigenic peptide encoded by the MAGE-A4 gene.
J Mol Biol. 2001 Jul 27;310(5):1167-76.
Marenholz I, Zirra M, Fischer DF, Backendorf C, Ziegler A, Mischke D.
Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library.
Genome Res. 2001 Mar;11(3):341-55.
2000
Wieser R, Volz A, Schnittger S, Jager U, Gruner H, Meran JG, Wimmer K, Ziegler a, Fonatsch C.
Mapping of leukaemia-associated breakpoints in chromosome band 3q21 using a newly established PAC contig.
Br J Haematol. 2000 Aug;110(2):343-50.
Wende H, Volz A, Ziegler A
Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster.
Immunogenetics. 2000 Jul;51(8-9):703-13.
Wieser R, Volz A, Vinatzer U, Gardiner K, Jager U, Mitterbauer M, Ziegler A, Fonatsch C.
Transcription factor GATA-2 gene is located near 3q21 breakpoints in myeloid leukemia.
Biochem Biophys Res Commun. 2000 Jun 24;273(1):239-45.
Uchanska-Ziegler B, Qiao X, Volz A, Nissim A, Ziegler A.
Human single-chain Fv fragments specific for natural killer cell receptors from phage display libraries.
Methods Mol Biol. 2000;121:219-37.
Ziegler A, Ehlers A, Forbes S, Trowsdale J, Volz A, Younger R, Beck S.
Polymorphisms in olfactory receptor genes: a cautionary note.
Hum Immunol. 2000 Dec;61(12):1281-4..
Ehlers A, Beck S, Forbes SA, Trowsdale J, Volz A, Younger R, Ziegler A.
MHC-linked olfactory receptor loci exhibit polymorphism and contribute to extended HLA/OR-haplotypes.
Genome Res. 2000 Dec;10(12):1968-78.
Rehm A, Rohr A, Seitz C, Wonigeit K, Ziegler A, Uchanska-Ziegler B.
Structurally diverse forms of HLA-B27 molecules are displayed in vivo in a cell type-dependent manner
Hum Immunol. 61(4):408-18, 2000
King A, Burrows TD, Hiby SE, Bowen JM, Joseph S, Verma S, Lim PB, Gardner L, Le Bouteiller P, Ziegler A, Uchanska-Ziegler B, Loke YW.
Surface expression of HLA-C antigen by human extravillous trophoblast.
Placenta. 2000 May;21(4):376-87
Maiti AK, Mattei MG, Jorissen M, Volz A, Ziegler A, Bouvagnet P.
Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.
Eur J Hum Genet. 2000 Dec;8(12):923-32.
Chames P, Hufton SE, Coulie PG, Uchanska-Ziegler B, Hoogenboom HR.
Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1-MAGE-A1 from a nonimmunized phage-Fab library.
Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7969-74.
Lamb FS, Barna TJ, Goud C, Marenholz I, Mischke D, Schutte BC.
Complex RNA processing of TDRKH, a novel gene encoding the putative RNA-binding tudor and KH domains.
Gene. 2000 Apr 4;246(1-2):209-18.
Mungall AJ, Beck S, Cann HM, Dunham I, Trowsdale J, Ziegler A.
Report of the Fourth International Chromosome 6 Workshop 1999. 10-12 June 1999. Cambridge, UK.
Cytogenet Cell Genet. 2000;88(3-4):173-96.
Ziegler, A., Ehlers, A., Forbes, S., Trowsdale, J., Uchanska-Ziegler, B., Volz, A. Younger, R., Beck, S.:
Polymorphic olfactory receptor genes and HLA loci constitute extended haplotypes.
In Major Histocompatibility Complex Evolution, Structure, and Function
(Kasahara, M., ed.), Springer Verlag, Tokyo, pp. 110-130 (2000)
Sander, T., Bockenkamp, B., Ziegler, A. and Janz, D.
Progress in mapping the gene for juvenile myoclonic epilepsy (EJM1) within the chromosomal region 6p21.3.
In Juvenile Myoclonic Epilepsy: The Janz Syndrome
(Schmitz, B. and Sander, T., eds.), pp. 173-180, Wrightson Biomedical Publishing Ltd., Petersfield, UK (2000)
1999
Ziegler A:
Basic mechanisms of monogenic inheritance.
Epilepsia.: 40 Suppl 3 4-8, 1999
Menssen R, Orth P, Ziegler A, Saenger W
Decamer-like conformation of a nona-peptide bound to HLA-B*3501 due to non-standard positioning of the C terminus.
J Mol Biol.: 285(2) 645-53, 1999
Wende H, Colonna M, Ziegler A, Volz A.
Organization of the leukocyte receptor cluster (LRC) on human chromosome 19q13.4.
Mamm Genome.: 10(2) 154-60, 1999
Janitz K, Wild A, Beck S, Savasta S, Beluffi G, Ziegler A, Volz A.
Genomic organisation of the HSET locus and the possible association of HLA-linked genes with Immotile Cilia Syndrome (ICS)
Immunogenetics.: 49 644-652, 1999
South AP, Cabral A, Ives JH, James CH, Mirza G, Marenholz I, Mischke D, Backendorf C, Ragoussis J, Nizetic D.
Human epidermal differentiation complex in a single 2.5 Mbp long continuum of overlapping DNA cloned in bacteria integrating physical and transcript maps.
J Invest Dermatol.: 112(6) 910-8, 1999
Sander T, Peters C, Kammer G, Samochowiec J, Zirra M, Mischke D, Ziegler A, Kaupmann K, Bettler B, Epplen JT, Riess O.
Association analysis of exonic variants of the gene encoding the GABAB receptor and idiopathic generalized epilepsy.
Am J Med Genet.: 88(4) 305-10, 1999
Lioumi M, Ferguson CA, Sharpe PT, Freeman T, Marenholz I, Mischke D, Heizmann C, Ragoussis J.
Isolation and characterization of human and mouse ZIRTL, a member of the IRT1 family of transporters, mapping within the epidermal differentiation complex.
Genomics. 62(2) 272-80, 1999
Lueders KK, Elliott RW, Marenholz I, Mischke D, DuPree M, Hamer D.
Genomic organization and mapping of the human and mouse neuronal beta2-nicotinic acetylcholine receptor genes.
Mamm Genome. 10(9):900-5, 1999
Sol, M.-A., Vacaresse, N., Lule, J., Davrinche, C., Gabriel, B., Teissie, J., Ziegler, A., Thomsen, M. and Benoist, H.
N-linked oligosaccharides can protect target cells from the lysis mediated by NK cells but not by cytotoxic T lymphocytes: role of NKG2-A.
Tissue Antigens 54, 113-121 (1999)
1998
Mischke D.
The complexity of gene families involved in epithelial differentiation. Keratin genes and the epidermal differentiation complex.
Subcell Biochem.: 31 71-104, 1998
Peters HC, Kammer G, Volz A, Kaupmann K, Ziegler A, Bettler B, Epplen JT, Sander T, Riess O.
Mapping, genomic structure and polymorphisms of the human GABABR1 receptor gene: evaluation of its involvement in idiopathic generalized epilepsy
Neurogenetics: 2 47-54, 1998
Borgmann A, von Stackelberg A, Baumgarten E, Uchanska-Ziegler B, Ziegler A, Wittig B, Henze G.
Immunotherapy of acute lymphoblastic leukemia by vaccination with autologous leukemic cells transfected with a cDNA expression plasmid coding for an allogeneic HLA class I antigen combined with interleukin-2 treatment.
J Mol Med.: 76(3-4) 215-21, 1998
Tibiletti MG, Trubia M, Ponti E, Sessa L, Acquati F, Furlan D, Bernasconi B, Fichera M, Mihalich A, Ziegler A, Volz A, Facco C, Riva C, Cremonesi L, Ferrari M, Taramelli R.
Physical map of the D6S149-D6S193 region on chromosome 6Q27 and its involvement in benign surface epithelial ovarian tumours.
Oncogene.: 16(12) 1639-42, 1998
Ziegler, A. und Volz, A.:
Geruchsbeeinflußte Partnerwahl, MHC und Fertilität
Bioforum: 21 284-291, 1998
Forus A, Berner JM, Meza-Zepeda LA, Saeter G, Mischke D, Fodstad O, Myklebost O.
Molecular characterization of a novel amplicon at 1q21-q22 frequently observed in human sarcomas.
Br J Cancer.: 78(4) 495-503, 1998
Seitz C, Uchanska-Ziegler B, Zank A, Ziegler A.
The monoclonal antibody HCA2 recognises a broadly shared epitope on selected classical as well as several non-classical HLA class I molecules.
Mol Immunol.: 35(13) 819-27, 1998
Wallace DF, Partridge J, Robertson A, Simpson VM, Worwood M, Bomford AB, Volz A, Ziegler A, Dooley JS, Walker AP.
A 6p22 reference map of leukocyte DNA: exclusion of rearrangement in four cases of atypical haemochromatosis.
Eur J Hum Genet.: 6(5) 523-6, 1998
Gregory SG, Vaudin M, Wooster R, Coleman M, Mischke D, Porter C, Schutte BC, White P, Vance JM.
Report of the fourth international workshop on human chromosome 1 mapping 1998.
Cytogenet Cell Genet. 1998;83(3-4):147-75
1997
Hammer A, Hutter H, Blaschitz A, Mahnert W, Hartmann M, Uchanska-Ziegler B, Ziegler A, Dohr G.
Amnion epithelial cells, in contrast to trophoblast cells, express all classical HLA class I molecules together with HLA-G.
Am J Reprod Immunol.: 37(2) 161-71, 1997
Garrido, F., Cabrera, T., Accolla, R.S., Bensa, J.C., Bodmer, W., Dohr, G., Drouel, M., Daucher, R., Fauchet, R., Ferrara, G.B., Ferrone, S., Giacomini, P., Kageshita, ......, Ziegler, A.:
HLA and cancer: 12th internationl histocompatibility workshop study
Int. Histocompatibility Workshop and Conference: - 445-452, 1997
Rhodes DA, Volz A, Jones T, Ziegler A, Trowsdale J
Complex duplications at 6p22.1, 6p11.2, 5q13, 5q15.1 and 5q13 revealed by fuorescent in situ hybridisation
DNA Seq.: 8 161-166, 1997
Volz A, Davies A, Ragoussis I, Laun K, Ziegler A.
Dissection of the 5.5 Mbp region directly telomeric of HLA-B including a long range restriction map, YAC and PAC contigs
DNA Seq.: 8 181-188, 1997
Volz A, Albig W, Doenecke D, Ziegler A.
Physical mapping of two histone gene clusters on human chromosome 6p22.1-22.2
DNA Seq.: 8 173-180, 1997
Malfroy L, Roth MP, Carrington M, Borot N, Volz A, Ziegler A, Coppin H.
Heterogeneity in rates of recombination in the 6-Mb region telomeric to the human major histocompatibility complex.
Genomics.: 43(2) 226-31, 1997
Beck S, Cann HM, Campbell RD, Dunham I, Inoko H, Jazwinska EC, Ragoussis J, Trowsdale J, Ziegler A.
Third single chromosome 6 workshop: meeting report
DNA Seq.: 8 113-129, 1997
Ziegler A.
Biology of Chromosome 6
DNA Seq.: 8 189-201, 1997
Sander T, Bockenkamp B, Hildmann T, Blasczyk R, Kretz R, Wienker TF, Volz A, Schmitz B, Beck-Mannagetta G, Riess O, Epplen JT, Janz D, Ziegler A.
Refined mapping of the epilepsy susceptibility locus EJM1 on chromosome 6.
Neurology.: 49(3) 842-7, 1997
B. Uchanska-Ziegler, M. Colonna, L. Granziero, A. Lanzavecchia, and A. Ziegler:
Leucocyte Typing VI
Garland Publishing: NK10.5 : CD158a and b Workshop: A novel monoclonal antibody (TÜ143) reactive with activated cells and those with low HLA 300-302, 1997
Grabbe J, Karau L, Welker P, Ziegler A, Henz BM.
Induction of MHC class II antigen expression on human HMC-1 mast cells.
J Dermatol Sci.: 16(1) 67-73, 1997
Wanner R, Zhang J, Dorbic T, Mischke D, Henz BM, Wittig B, Rosenbach T.
The promoter of the HaCaT keratinocyte differentiation-related gene keratin 4 contains a functional AP-2 binding site.
Arch Dermatol Res.: 289(12) 705-8, 1997
1996
Weith A, Brodeur GM, Bruns GA, Matise TC, Mischke D, Nizetic D, Seldin MF, van Roy N, Vance J.
Report of the second international workshop on human chromosome 1 mapping 1995.
Cytogenet Cell Genet.: 72(2-3) 114-44, 1996
Volz A, Ziegler A
Physical mapping of a 6 Mbp region directly telomeric of the HLA-complex.
DNA Seq.: 7(1) 61-2, 1996
Haas N, Iwen W, Grabbe J, Uchanska-Ziegler B, Czarnetzki BM.:
MHC class II antigen expression is increased in different forms of urticaria.
Int Arch Allergy Immunol.: 109(2) 177-82, 1996
Mischke D, Korge BP, Marenholz I, Volz A, Ziegler A.
Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ( epidermal differentiation complex ) on human chromosome 1q21.
J Invest Dermatol.: 106(5) 989-92, 1996
Carmichael P, Kerr LA, Kelly A, Lombardi G, Zeigler BU, Ziegler A, Trowsdale J, Lechler R.
The TAP complex influences allorecognition of class II MHC molecules.
Hum Immunol.: 50(1) 70-7, 1996
Marenholz I, Volz A, Ziegler A, Davies A, Ragoussis I, Korge BP, Mischke D
Genetic analysis of the epidermal differentiation complex (EDC) on human chromosome 1q21: chromosomal orientation, new markers, and a 6-Mb YAC contig.
Genomics.: 37(3) 295-302, 1996
Hutter H, Hammer A, Blaschitz A, Hartmann M, Ebbesen P, Dohr G, Ziegler A, Uchanska-Ziegler B.
Expression of HLA class I molecules in human first trimester and term placenta trophoblast [published erratum appears in Cell Tissue Res 1997 Mar;287(3):625]
Cell Tissue Res.: 286(3) 439-47, 1996
Wicki R, Marenholz I, Mischke D, Schafer BW, Heizmann CW.
Characterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21.
Cell Calcium.: 20(6) 459-64, 1996
Cann, H.M., Campbell, R.D. and Ziegler, A.
Report of the committee on the genetic constitution of chromosome 6.
In Human Gene Mapping, 1995: A Compendium (Cuticchia, A.J., Chipperfield, M.A. and Foster, P.A., eds.), pp. 473-515, Johns Hopkins University Press, Baltimore (1996)
1995
Cann, H.M., Campbell, R.D., Volz, A. Ziegler, A.:
Human Gene Mapping 1994 (A.J. Cuticchia, ed.)
Johns Hopkins Univ. Press: Report of the the committee on the genetic constitution of chromosome 6 353-358, 1995
Hennies HC, Kuster W, Mischke D, Reis A.
Localization of a locus for the striated form of palmoplantar keratoderma to chromosome 18q near the desmosomal cadherin gene cluster.
Hum Mol Genet.: 4(6) 1015-20, 1995
Mischke, D., Marenholz, I., Volz, A., Ziegler, A. and Korge, B.:
Physikalische Kartierung und molekulare Charakterisierung eines funktionellen Clusters epidermaler Differenzierungsgene auf Chromosom 1q21
Med Genetik: 2 302-303, 1995
Sander T., Janz D., Ramel C., Ross C.A., Paschen W., Hildmann T., Wienker T.F., Bianchi A., Bauer G., Sailer U., Berek K., Neitzel H., Volz A., Ziegler A., Schmitz B., Beck-Mannagetta G.:
Refinement of the map position of the human GluR6 Kainate Receptor Gene (GRIK2) and lack of association and linkage with idiopathic generalized epilepsies
Neurology.: 45 1713-20, 1995
Förster HH, Wäsch R, Kretschmar T, Mischke D, Uchanska-Ziegler B, Ziegler A, Schmitt M, Wahn HU.
Genetic markers on chromosome 19p and prenatal diagnosis of HLA class II-deficient combined immunodeficiency.
Pediatr Res.: 38(5) 812-6, 1995
Uchanska-Ziegler, B., Hirsch, T., Wille, G., Zank, A. and Ziegler, A.
Spermatozoa as tools to group leukocyte-directed monoclonal antibodies.
In Leukocyte Typing V: White Cell Differentiation Antigens (Schlossman, S., Boumsell, L., Gilks, W., Harlan, J., Kishimoto, T., Morimoto, C., Ritz, J., Shaw, S., Silverstein, R., Springer, T., Tedder, T. and Todd, R., eds.), Oxford University Press, Oxford, pp. 220-229 (1995)
Cann, H.M., Campbell, R.D., Volz, A. and Ziegler, A.
Report of the committee on the genetic constitution of chromosome 6.
In Human Gene Mapping, 1994: A Compendium (Cuticchia, A.J., ed.), pp. 353-385, Johns Hopkins University Press, Baltimore (1995)
1994
Volz A, Weiss E, Trowsdale J, Ziegler A.
Presence of an expressed beta-tubulin gene (TUBB) in the HLA class I region may provide the genetic basis for HLA-linked microtubule dysfunction.
Hum Genet.: 93(1) 42-6, 1994
Reis A, Hennies HC, Langbein L, Digweed M, Mischke D, Drechsler M, Schrock E, Royer-Pokora B, Franke WW, Sperling K, et al.
Keratin 9 gene mutations in epidermolytic palmoplantar keratoderma (EPPK).
Nat Genet.: 6(2) 174-9, 1994
Urban RG, Chicz RM, Lane WS, Strominger JL, Rehm A, Kenter MJ, UytdeHaag FG, Ploegh H, Uchanska-Ziegler B, Ziegler A.
A subset of HLA-B27 molecules contains peptides much longer than nonamers.
Proc Natl Acad Sci U S A.: 91(4) 1534-8, 1994
Volz A, Boyle JM, Cann HM, Cottingham RW, Orr HT, Ziegler A
Report of the Second International Workshop on Human Chromosome 6.
Genomics.: 21(2) 464-72, 1994
Zheng H, Bhavsar D, Volz A, Ziegler A, Drysdale J.
Exclusion of ferritins and iron-responsive element (IRE)-binding proteins as candidates for the hemochromatosis gene.
Hum Genet.: 94(2) 159-64, 1994
Zouboulis CC, Krieter A, Gollnick H, Mischke D, Orfanos CE.
Progressive differentiation of human sebocytes in vitro is characterized by increasing cell size and altering antigen expression and is regulated by culture duration and retinoids.
Exp Dermatol.: 3(4) 151-60, 1994
Cann, H.M., Campbell, R.D., Volz, A. und Ziegler, A.:
Human Gene Mapping, 1993: A Compendium (Cuticchia, A.J. and Pearson, P.L., eds.)
Johns Hopkins Univ. Press: Report of the committee on the genetic constitution of chromosome 6 302-325, (1994)
1993
Trent JM, Ziegler A.
Report of the First International Workshop on Human Chromosome 6 Mapping. Ann Arbor, Michigan, June 7-9, 1992.
Cytogenet Cell Genet.: 62(2-3) 67-87, 1993
Uchanska-Ziegler B, Nossner E, Schenk A, Ziegler A, Schendel DJ.
Soluble T cell receptor-like properties of an HLA-B35-specific monoclonal antibody (TU165).
Eur J Immunol.: 23(3) 734-8, 1993
Mischke D.
Frequencies of human keratin 10 alleles.
Hum Mol Genet.: 2(5) 618, 1993
Wanner R, Forster HH, Tilmans I, Mischke D.
Allelic variations of human keratins K4 and K5 provide polymorphic markers within the type II keratin gene cluster on chromosome 12.
J Invest Dermatol.: 100(6) 735-41, 1993
Shortle VP, Malaspina P, Fox M, Dooley JS, Volz A, Ziegler A, Trowsdale J, Morrison KM, Edwards YH
A cosmid library specific for human chromosome regions 6p21.3 and 6q27.
Mamm Genome.: 4(9) 493-8, 1993
Zouboulis CC, Korge BP, Mischke D, Orfanos CE.
Altered proliferation, synthetic activity, and differentiation of cultured human sebocytes in the absence of vitamin A and their modulation by synthetic retinoids.
J Invest Dermatol.: 101(4) 628-33, 1993
Volz A, Korge BP, Compton JG, Ziegler A, Steinert PM, Mischke D.
Physical mapping of a functional cluster of epidermal differentiation genes on chromosome 1q21.
Genomics.: 18(1) 92-9, 1993
Steinle A, Reinhardt C, Nossner E, Uchanska-Ziegler B, Ziegler A, Schendel DJ.
Microheterogeneity in HLA-B35 alleles influences peptide-dependent allorecognition by cytotoxic T cells but not binding of a peptide-restricted monoclonal antibody.
Hum Immunol.: 38(4) 261-9, 1993
Schaller G, Lengyel E, Pantel K, Hardt W, Mischke D.
Keratin expression reveals mosaic differentiation in vaginal epithelium.
Am J Obstet Gynecol.: 169(6) 1603-7, 1993
Ziegler, A., Campbell, R.D., Trent, J.M. and Cann, H.M.
Report of the committee on the genetic constitution of chromosome 6.
In Chromosome Coordinating Meeting (1992) (Cuticchia, A.J., Pearson, P.L. and Klinger, H.P., eds.)
Genome Priority Reports 1, 269-294 (1993)
Ziegler, A. and Orr, H.T.
Report on the Second International Chromosome 6 Workshop.
HUGO Newsletter 1, 2-3 (1993)
1992
Volz A, Fonatsch C, Ziegler A.
Regional mapping of the gene for autosomal dominant spinocerebellar ataxia (SCA1) by localizing the closely linked D6S89 locus to 6p24.2----p23.05.
Cytogenet Cell Genet.: 60(1) 37-9, 1992
Korge BP, Gan SQ, McBride OW, Mischke D, Steinert PM.
Extensive size polymorphism of the human keratin 10 chain resides in the C-terminal V2 subdomain due to variable numbers and sizes of glycine loops.
Proc Natl Acad Sci U S A.: 89(3) 910-4, 1992
Wanner R, Tilmans I, Mischke D.
Avoiding strand reassociation in direct sequencing of double-stranded PCR products with thermolabile polymerases.
PCR Methods Appl.: 1(3) 193-4, 1992
Kelly A, Powis SH, Kerr LA, Mockridge I, Elliott T, Bastin J, Uchanska-Ziegler B, Ziegler A, Trowsdale J, Townsend A.
Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex.
Nature.: 355(6361) 641-4, 1992
Ziegler, A. und Volz, A.:
Pulsed field gel electrophoresis, Methods in Molecular Biology
Humana Press: Rotating field gel electrophoresis (ROFE) 63-72, 1992
Asada M, Schaart FM, Detmar M, Mischke D, de Almeida HL Jr, Gollnick H, Orfanos CE.
Growth characteristics and differentiation of basal cell carcinoma in vitro--immunohistochemical, gel electrophoretic, and ultrastructural analysis.
J Invest Dermatol.: 99(4) 474-81, 1992
Korge BP, Compton JG, Steinert PM, Mischke D.
The two size alleles of human keratin 1 are due to a deletion in the glycine-rich carboxyl-terminal V2 subdomain.
J Invest Dermatol.: 99(6) 697-702, 1992
Ziegler, A., Geiger, K.-H. and Volz, A.
Technik und Anwendung der Makrorestriktionsanalyse in der Mikrobiologie.
BIOforum 1, 29-30 (1992)
1991
Huschenbett J, Volz A, Pfeifer L, Speer A
Possibilities and limitations of carrier diagnosis in families with Duchenne muscular dystrophy caused by deletions in the major hot spot region using pulsed-field gel electrophoresis.
Biomed Biochim Acta.: 50(12) 1205-12, 1991
Thewes M, Stadler R, Korge B, Mischke D.
Normal psoriatic epidermis expression of hyperproliferation-associated keratins.
Arch Dermatol Res.: 283(7) 465-71, 1991
Mischke D, Genka T, Wille G, Lobeck H, Wild AG.
Keratins as molecular markers of epithelial differentiation: differential expression in crypt epithelium of human palatine tonsils.
Ann Otol Rhinol Laryngol.: 100(5 Pt 1) 372-7, 1991
Ragoussis J, Jones TA, Sheer D, Shrimpton AE, Goodfellow PN, Trowsdale J, Ziegler A
Isolation of probes specific to human chromosomal region 6p21 from immunoselected irradiation-fusion gene transfer hybrids.
Genomics.: 10(3) 598-607, 1991
Braun J, Hirsch T, Krause W, Ziegler A
Evaluation of the acrosome reaction using monoclonal antibodies against different acrosomal antigens--comparison with the triple stain technique.
Int J Androl.: 14(6) 431-6, 1991
Ziegler, A.
Immuntherapie.
In Bronchialkarzinom (Dorow, P., Rühle, K.-H. and Thalhofer, S., eds.), Walter de Gruyter, Berlin, pp. 201-205 (1991)
Ragoussis, J., Jones, T., Monaco, A., Sheer, D., Ziegler, A., Boyle, J., Kendall, E., Campbell, R.D. and Trowsdale, J.
Irradiation-fusion-gene transfer hybrids, new probes and YACs for the 6p21 region.
BioTech Forum 6, "Advances in Molecular Genetics 4", 257-261(1991)
Desoye, G., Dohr, G.A. and Ziegler, A.
Biology of disease: Expression of human major histocompatibility antigens on germ cells and early preimplantation embryos.
Lab. Invest. 64, 306-312 (1991)
Ziegler, A. Field, L.L. and Sakaguchi, A.Y.
Report of the committee on the genetic constitution of chromosome 6.
Cytogenet. Cell Genet. 58, 295-336 (1991)
1990
Dohr G, Blaschitz A, Hirsch T, Kohlstadt S, Uchanska-Ziegler B, Ziegler A.
Immunoelectron microscopy of human spermatozoa.
Andrologia.: 22 Suppl 1 92-100, 1990
Ziegler A, Hirsch T, Krause W, Neumann K, Schieferstein G, Dohr G, Kohlstadt S, Uchanska-Ziegler B.
Monoclonal antibodies against antigens expressed by human sperm.
Andrologia.: 22 Suppl 1 101-9, 1990
Feenstra O, Dohr G, Siwetz G, Hirsch T, Ziegler A
Sperm detection using monoclonal antibodies
Beitr Gerichtl Med.: 48 17-20, 1990
Feenstra, O., Dohr, G., Siwetz, G., Hirsch, T. and Ziegler, A.
Monoclonal antibodies detect sperm antigens in seminal stains.
Adv. Forensic Haemogenet. 3, 358-360 (1990)
Mischke D, Wille G, Wild AG.
Allele frequencies and segregation of human polymorphic keratins K4 and K5.
Am J Hum Genet.: 46(3) 548-52, 1990
Schaller G, Mischke D, Wild AG.
[Differentiation behavior of human vaginal epithelium exemplified by keratin expression]
Geburtshilfe Frauenheilkd.: 50(5) 397-402, 1990
Korge B, Stadler R, Mischke D.
Effect of retinoids on hyperproliferation-associated keratins K6 and K16 in cultured human keratinocytes: a quantitative analysis.
J Invest Dermatol.: 95(4) 450-5, 1990
Ziegler, A., Field, L.L. and Sakaguchi, A.Y.
Report of the committee on the genetic constitution of chromosome 6.
Cytogenet. Cell Genet. 55, 118-121 (1990)
1989
Momburg F, Ziegler A, Harpprecht J, Moller P, Moldenhauer G, Hammerling GJ.
Selective loss of HLA-A or HLA-B antigen expression in colon carcinoma.
J Immunol.: 142(1) 352-8, 1989
Schobel WA, Schieferstein G, Knapp R, Uchanska-Ziegler B, Ziegler A.
Identification of human spermatozoa antigens using monoclonal antibodies and the alkaline phosphatase anti-alkaline phosphatase-technique.
Andrologia.: 21(1) 35-41, 1989
Muller CP, Ziegler A, Steinke B, Horny HP, Waller HD
Myelosarcomatosis of the skin preceding leukemic generalization of acute myelomonocytic leukemia.
Blut.: 58(3) 165-7, 1989
Ragoussis J, Bloemer K, Pohla H, Messer G, Weiss EH, Ziegler A.
A physical map including a new class I gene (cda12) of the human major histocompatibility complex (A2/B13 haplotype) derived from a monosomy 6 mutant cell line.
Genomics.: 4(3) 301-8, 1989
Weiss EH, Ziegler A
HLA-genes and function.
Immunol Today.: 10(8) S16-8, 1989
Schulz P, Wachter E, Hochstrasser K, Wild AG, Mischke D.
Sequence of a human keratin 13 specific cDNA encompassing coil 1B through the 3' end.
Biochem Biophys Res Commun.: 162(3) 1522-7, 1989
Mischke D, Wachter E, Hochstrasser K, Wild AG, Schulz P
The N-, but not the C-terminal domains of human keratins 13 and 15 are closely related.
Nucleic Acids Res.: 17(19) 7984, 1989
1988
Schendel DJ, Ziegler A.
Serological and biochemical characterization of HLA-A molecules bearing a public epitope.
Immunogenetics.: 27(1) 61-5, 1988
Ragoussis J, Bloemer K, Weiss EH, Ziegler A.
Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis.
Immunogenetics.: 27(1) 66-9, 1988
Lobeck H, Hollandt J, Mischke D, Wild G.
[Heterogeneity of cytokeratins of epithelial cells in relation to cell differentiation (the example of laryngeal epithelium)]
Verh Dtsch Ges Pathol.: 72 229-32, 1988
Desoye G, Dohr GA, Motter W, Winter R, Urdl W, Pusch H, Uchanska-Ziegler B, Ziegler A.
Lack of HLA class I and class II antigens on human preimplantation embryos.
J Immunol.: 140(12) 4157-9, 1988
Wild GA, Wille G, Mischke D.
Lateral cervical (branchial) cyst epithelia express upper digestive tract-type cytokeratins. Polyclonal antibody studies.
Ann Otol Rhinol Laryngol.: 97(4 Pt 1) 365-72, 1988
1987
Schwarting R, Gerdes J, Ziegler A, Stein H.
Immunoprecipitation of the interleukin-2 receptor from Hodgkin's disease derived cell lines by monoclonal antibodies.
Hematol Oncol.: 5(1) 57-64, 1987
Fonatsch C, Gradl G, Ragoussis J, Ziegler A.
Assignment of the TCP1 locus to the long arm of human chromosome 6 by in situ hybridization.
Cytogenet Cell Genet.: 45(2) 109-12, 1987
Toffenetti J, Mischke D, Pardue ML
Isolation and characterization of the gene for myosin light chain two of Drosophila melanogaster.
J Cell Biol.: 104(1) 19-28, 1987
Lobeck H, Beiswenger M, Reichelt A, Zuschneid W, Mischke D, Wild G.
[Intermediate filaments and carcinoembryonic antigen (CEA) in cancers of the head of the pancreas and Vater's ampulla and their precursors (a semiquantitative immunohistochemical study)]
Verh Dtsch Ges Pathol.: 71 294-8, 1987
Mischke D, Wild G
Polymorphic keratins in human epidermis.
J Invest Dermatol.: 88(2) 191-7, 1987
Busch FW, Langer M, Pawelec G, Ziegler A, Wernet P, Buhring HJ, Meyer P, Muller C:
HLA-class II antigens on human hematopoietic progenitors.
Blut.: 54(3) 179-88, 1987
Koscielniak E, Bruchelt G, Treuner J, Uchanska-Ziegler B, Dopfer R, Vallbracht A, Niethammer D.
Kinetics of restoration of interferon production after bone marrow transplantation in man.
Bone Marrow Transplant.: 1(4) 379-87, 1987
Wild G, Mischke D, Lobeck H, Kastenbauer E.
The lateral cyst of the neck: congenital or acquired?
Acta Otolaryngol Stockh.: 103(5-6) 546-50, 1987
Dohr GA, Motter W, Leitinger S, Desoye G, Urdl W, Winter R, Wilders-Truschnig MM, Uchanska-Ziegler B, Ziegler A.
Lack of expression of HLA [corrected] class I and class II molecules on the human oocyte [published erratum appears in J Immunol 1987 Nov 15;139(10):3550]
J Immunol.: 138(11) 3766-70, 1987
Wild GA, Lobeck H, Mischke D.
[Keratin expression in normal and malignant transformed squamous epithelium of the digestive mucosa of the head]
Laryngol Rhinol Otol Stuttg.: 66(12) 615-21, 1987
1986
Feller AC, Parwaresch MR, Stein H, Ziegler A, Herbst H, Lennert K
Immunophenotyping of T-lymphoblastic lymphoma/leukemia: correlation with normal T-cell maturation.
Leuk Res.: 10(8) 1025-31, 1986
Lobeck H, Haase U, Pfannkuch F, Mischke D, Wild G
[Patterns of defined cytokeratins in normal epithelium, hyperplasia and carcinomas of the mucosa in the upper digestive tract (an immunohistochemical study)]
Verh Dtsch Ges Pathol.: 70 238-42, 1986
Wild GA, Mischke D.
Variation and frequency of cytokeratin polypeptide patterns in human squamous non-keratinizing epithelium.
Exp Cell Res.: 162(1) 114-26, 1986
Ziegler A, Heinig J, Muller C, Gotz H, Thinnes FP, Uchanska-Ziegler B, Wernet P.
Analysis by sequential immunoprecipitations of the specificities of the monoclonal antibodies TU22,34,35,36,37,39,43,58 and YD1/63.HLK directed against human HLA class II antigens.
Immunobiology.: 171(1-2) 77-92, 1986
Kuhlmann D, Dohr G, Pusch HH, Scherbaum W, Schieferstein G, Uchanska-Ziegler B, Ziegler A.
Absence of HLA class I and class II antigens as well as beta 2-microglobulin from normal and pathological human spermatozoa.
Tissue Antigens.: 27(3) 179-84, 1986
Spring B, Pawelec G, Ziegler A.
Gamma ray-induced mutants as a tool for the production and characterisation of monoclonal antibodies against HLA-alloantigens.
Tissue Antigens.: 27(4) 201-8, 1986
Ragoussis J, van der Bliek A, Trowsdale J, Ziegler A.
Mapping of HLA genes using pulsed-field gradient electrophoresis.
FEBS Lett.: 204(1) 1-4, 1986
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