Institute of Laboratory Medicine and Pathobiochemistry

Projects

• biomaterial network
• Characterization of the synergistic cytotoxic effect mediated by saponins and protein toxins
• Development of a novel strategy for cancer therapy by combining chimeric adaptertoxins and triterpenoids
• Development of an Activity Assay for ADP-Ribosylating Toxins
• Fhit-mediated modulation of the ß-catenin
• Function of heterophilic interactions of PrP for the pathogenesis of TSE
• Glykostrukturfabrik2
• HbA1c biosensor
• Immunoadaptertoxins: Therapeutic Mechanism in a Mouse Model
• Involvement of Toll like receptors (TLR) in inflammatory reactions of the toxic oil syndrome (TOS)
• Molecular interactions between hemochromatosis protein HFE and proteins of iron metabolism
• Partikuläre Selektin-Inhibitoren zur Behandlung von entzündlichen Erkrankungen
• Posttranslational modulation of tight junction structure and function
• Recombinant fusions proteins for ADEPT and radio-ADEPT of colon carcinomas
• Strukturelle Grundlagen der Funktion des Rezeptors L-Selektin
• Substantial changes of cellular iron homeostasis during megakaryocytic differentiation of K562 cells
• Suppression of the immune activation in chronic rheumatoid arthritis by reduction of TNF- release from macrophages
• TFF-Peptides: Molecular mechanisms of action and potential use as diagnostic marker

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