Institute of Biochemistry CCM

Projects

• Affinitätsmarkierung des aktiven Zentrums von Lipoxygenasen durch Azidofettsäuren
• Bakterielle NiFe-Hydrogenasen: Schlüsselreaktionen der biologischen Aktivierung von molekularem Wasserstoff
• Cryo-electron microscopy of the protein targeting and translocation machinery
• DFG priority programme Selenoproteins, phase 3
• Eicosanoids and nitric oxide. Mediators of cardiovascular, cerebral and neoplastic diseases.
• Entwicklung und vorklinische Testung von kleinen Molekülen als Aktivatoren des proapoptotischen Bcl-2-Analogons Bak
• Expression regulation of monoamine oxidases
• Function of proteasomes in CVB3 antigen presentation
• Functional Characterisation of the HERP Protein
• Immune adaption
• Impact of LOX-inhibitors on cellular oxidation of LDL
• Interfaces
• Investigation of the influence of cytokines and infection on proteasomal antigen processing
• Kinetic modelling of the intracellular protein degradation
• Lipoxygenases and foam cell formation
• Membrane binding of lipoxygenase
• Optimized molecular libraries
• Opt.ß-Faltblattmodul
• Oxidative Modification of LDL as pathogenetic process in Atherogenesis.
• Proteasomale Antigenprozessierung
• Protein Cofactor Interactions
• Publ. KR 1915/4-1
• Removal of nitric oxide in the vasculature by the catalytic activity of lipoxygenases
• Structure and Function of membran bound receptors
• Untersuchungen zu den strukturellen Voraussetzungen für die Penetration des Sauerstoffs bei Lipoxygenasen
• von Molekülen zu Modulen

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