Symposium

Research Unit FOR 667

Epithelial Mechanisms in Renal Volume Regulation

 


Projects

Projects Overview

No. Title Area of Expertise Project Leader(s)

1

Functional characterization of intracellular sorting receptors in transepithelial transport processes in the kidney

cell biology, endo-cytosis, intracellular protein transport, transgenic animal models, renal physiology

Thomas Willnow
Max Delbrück Center for Molecular Medicine

2 Biology of the cation-chloride-cotransporter, thick ascending limb of Henle’s loop Anatomy and cell biology, nephrology, epithelial transport

Sebastian Bachmann
Charité - Universitätsmedizin Berlin Campus Mitte
Institute of Cardiorenal Anatomy

3 Identification and characterization of proteins controlling the transport of aquaporin-2 in renal principal cells pharmacology, cell and molecular biology, biochemistry

Enno Klußmann
Research Center for Molecular Pharmacology
Berlin-Buch
Walter Rosenthal
Research Center for Molecular Pharmacology
Berlin-Buch

4 Transcriptional regulation of epithelial differentiation in the kidney Developmental biology, cell biology, nephrology

Kai Schmidt-Ott
Max-Delbrück-Centrum für Molekulare Medizin (MDC)
Robert-Rössle-Str. 10
13125 Berlin

 

5 The role of the tubular renin-angiotensin and the kallikrein kinin systems in kidney function and hypertensive nephropathy Generation of trans-genic mice and rats and knockout mice
Cardiovascular phe-notyping of animal models
Cardiovascular hor-mones (angiotensin, bradykinin, seroto-nin)

Michael Bader
Max Delbrück Center for Molecular Medicine

 

7 Role of ClC-5 and other vesicular CLC transporters in renal endocytosis
and tubular transport
Physiology, cell biology, molecular medicine, biophysics

Thomas Jentsch
Leibnitz Institute for Molecular Pharmacology

 

8 Dysfunction in epithelial sodium transport under proteinuric conditions Anatomy and cell biology, nephrology, epithelial transport

Franziska Theilig
Charité - Universitätsmedizin Berlin Campus Mitte
Institute of Cardiorenal Anatomy
Harm Peters
Charité - Universitätsmedizin Berlin Campus Mitte
Nephrological Clinic

 

Core Facilities

  Multi user group for transmission electron microscopy and scanning electron microsocopy
Ultrastructure immune electron
microscopy

Sebastian Bachmann
Charité - Universitätsmedizin Berlin Campus Virchow-Klinikum

  Confocal digital analysis Anatomy, physiology

Dieter Blottner
Charité - Universitätsmedizin Campus Benjamin Franklin

Z Administrative office of the FOR 667   Sebastian Bachmann
Coordinator of FOR 667

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