Core Facility - Dieter Blottner
   
Date of Birth:
30 September 1955
Nationality:
German
 
 
EDUCATION:
 
1976-1982
Studies in Biology, English and American Literature
1988
Human Medicine (Physikum)
1986
Dr. rer.nat. degree
1992
Habilitation
PROFESSIONAL EXPERIENCE:
 
1982-1986
Research and Teaching Assistant, Anatomy Department, University of Regensburg (Dr.rer.nat.)
1986-1989
Research and Teaching Assistant, Anatomy and Cell Biology, University of Marburg
1989-2004
Associate Professor of Anatomy, Freie Universität Berlin (Habilitation)
2001
Co-founder Center of Space Medicine Berlin (cf. www.zwmb.de)
since 2005
Group Leader Neuromuscular System, Vegetative Anatomy, Charité Universitätsmedizin Berlin
 
 
RESEARCH INTERESTS:

Cell signalling pathways
Autonomic nervous system
Musculoskeletal system
Neuromuscular development and plasticity
Growth factors
Nitric oxide and related signals
Space medicine (Skeletal muscle atrophy and countermeasures, cf. www.zwmb.de)
HONORS/AWARDS:
2002
Goldener Frankie Award (for best lecture in preclinical medicine)
2003
Goldener Frankie Award (for best lecture in preclinical medicine)


TOP TEN PUBLICATIONS:

  
1. Blottner D. Nitric oxide and fibroblast growth factor in autonomic nervous system: short-and long-term messengers in autonomic pathway and target-organ control. Prog Neurobiol. 1997 Mar;51(4):423-38. Review
2. Schoser BG, Luck G, Blottner D. Partial loss of NADPH-diaphorase/nitric oxide synthase-complex in amyotrophic lateral sclerosis and human type-II myofiber atrophy. Neurosci Lett. 1997 Aug 15;231(3):163-6.
3. Vogel M, Luck G, Bachmann S, Blottner D. NOS type-1 mRNA expression and protein localization in spinal autonomic neurons. Neuroreport. 1997 Oct 20;8(15):3389-93.
4. Blottner D. Lück G. Nitric oxide synthase (NOS) in mouse skeletal muscle development and
differentiated myoblasts. Cell Tissue Res. 1998 May;292(2):293-302.

5. Blottner D.Nitric oxide and target-organ control in the autonomic nervous system: anatomical distribution, spatiotemporal signaling, and neuroeffector maintenance. J Neurosci Res. 1999 Oct 1;58(1):139-51. Review.
6. Lück G, Hoch W, Hopf C, Blottner D. Nitric oxide synthase (NOS-1) coclustered with agrin-induced
AChR-specializations on cultured skeletal myotubes. Mol Cell Neurosci. 2000 Sep;16(3):269-81.

7. Schoser BG, Wehling S, Blottner D. Cell death and apoptosis-related proteins in muscle biopsies of sporadic amyotrophic lateral sclerosis and polyneuropathy. Muscle Nerve. 2001 Aug;24(8):1083-9.
8. Leimert M, Blottner D. Neuronal nitric oxide synthase (bNOS) messenger RNA and protein expression in developing rat brainstem nuclei. Neurosci Lett. 2003 May 15;342(1-2):57-60.
9. Rudnick J, Puttmann B, Tesch PA, Alkner B, Schoser BG, Salanova M, Kirsch K,Gunga HC, Schiffl G, Lück G, Blottner D. Differential expression of nitric oxide synthases (NOS 1-3) in human skeletal muscle following exercise countermeasure during 12 weeks of bed rest. FASEB J. 2004 Aug;18(11):1228-30.
10. Püttmann B, Gerlach EM, Krüger M, Blottner D.Nitric oxide signals in skeletal myotubes induced by neuromuscular contacts in vitro. NeuroSignals (2005) 14:85-95.

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