|
Project
5 - Michael Bader |
| |
|
| Date
of Birth: |
04
June 1958 |
| Nationality:
|
German |
| |
|
| EDUCATION: |
|
| 1984 |
Diploma
(Biology) at the University of Freiburg, Germany |
| 1989 |
Ph.D.
at the University of Freiburg, Germany |
| 1997 |
Habilitation in Pharmacology and Toxicology, Free University Berlin |
| 2003 |
Professorship
in Pharmacology and Toxicology, Charité - University Medicine
Berlin |
| |
|
PROFESSIONAL
EXPERIENCE:
|
|
| 1989-1993 |
Research
assistant in the lab of Prof. Dr. Detlev Ganten at the Department
of Pharmacology and German Institute for High Blood Pressure Research,
University of Heidelberg
|
| since
1994 |
Group
Leader in the Hypertension Research at the Max-Delbrück-Center
for Molecular Medicine (MDC), Berlin-Buch |
| 1995-1998 |
Vice-Coordinator of the Hypertension Research at the MDC |
| |
|
| RESEARCH
INTERESTS: |
Molecular biology of genes coding for cardiovascular hormones
Generation and characterization of genetically altered animal
models for the functional analysis of cardiovascular hormones
Development of transgenic technology in mouse and rat / Embryonic
stem cell technology
|
|
TOP PUBLICATIONS: |
|
| 1.
|
Walther
DJ, Peter JU, Winter S, Höltje M, Paulmann N, Grohmann M,
Vowinckel J, Alamo-Bethencourt V, Wilhelm CS, Ahnert-Hilger G,
Bader M. Serotonylation of small GTPases is a signal transduction
pathway that triggers platelet a-granule release. Cell 2003, 115:
851-862. |
| 2.
|
Walther
D, Peter JU, Bashammakh S, Hörtnagl H, Voits M, Fink H, Bader
M. Synthesis of serotonin by a second tryptophan hydroxylase isoform.
Science 2003; 299: 76 |
| 3.
|
Pesquero
JB, Araujo RC, Heppenstall PA, Stucky CL, Silva J-AJr, Walther
T, Oliveira SM, Pesquero JL, Paiva AC, Calixto JB, Lewin GR, Bader
M. Hypoalgesia and altered inflammatory responses in mice lacking
kinin B1 receptors. Proc Natl Acad Sci USA 2000; 97: 8140-8145 |
| 4. |
Silva
J-AJr, Araujo RC, Baltatu O, Oliveira SM, Tschöpe C, Fink
E, Hoffmann S, Plehm R, Chai KX, Chao L, Chao J, Ganten D, Pesquero
JB, Bader M: Reduced cardiac hypertrophy and altered blood pressure
control in transgenic rats with the human tissue kallikrein gene.
FASEB J 2000;14:1858-1860 |
| 5.
|
Schinke
M, Baltatu O, Böhm M, Peters J, Rascher W, Bricca G, Lippoldt
A, Ganten D, Bader M. Blood pressure reduction and diabetes insipidus
in transgenic rats deficient in brain angiotensinogen. Proc Natl
Acad Sci USA 1999;96:3975-3980 |
|