Links to the world of genomics

Sequencing centers

• IMB-Jena (german sequencing center)
• The Sanger Centre (sequencing center)

  Outstanding institutes

• Cold spring habour laboratory
• EMBL
• Max Delbrück Center
• The Jackson Laboratory (mice and more)

  Data resources

• Pedro´s pages(all you need..)
• Expasy (nice swiss server!)
• Entrez (find DNA or protein at NCBI)
• Japanese genomics
• MIPS (protein data base)

  InsilicoBiology / Bioinformatics

  Sequence analysis tools:
• BLOCKS Server (highly conserved protein motifs)
• EBI (European Bioinformatics Institute)
• GeneQuiz (functional predictions of yeast genes)
• Homology search (BLAST & BEAUTY)
• Mixed tools (DNA-translation, molecular weigth calculation and more...)
• PredictProtein (protein structural predictions form sequence data)
• Sequence analysis (from IMB-jena)

General tools

• Dictionnary
• Literature search (MEDLINE from NIH)
• Hotbot (Internet search engine)
• google (Internet search engine)

SAGE-links

SAGE, which stands for serial analysis of gene expression, has been  developped by Dr. Velculescu and coworkers in the lab of Dr. K. Kinzler and Dr. B. Vogelstein at Johns Hopkins Oncology center at Baltimore. The method has been first described in 1995 (1). From the same group several SAGE-projects has been published in 1997 (2, 3, 4). The Kinzler/Vogelstein laboratory supports a (or better: "the") SAGE-Homepage, a second is supported by Genzyme, the company owning the patent rights. Recentily, a SAGE-project section with a own SAGE-Page has been initiated at the NCBI.

further links

Academic

Several ongoing SAGE projects and additional information:
• Virtual SAGE
• SAGE at the MIPS (Yeast)
• Yeast (grown on different carbon sources) 1 and 2
• NO-mediated toxicity in neurons
• Brain tumors

  
  Technical modifications:

• Enhanced concatamer cloning
• MicroSAGE
• Additional heating step

  Commercial

• Genzyme (genomic company (SAGE pat.))
• Collaboration (Bayer / Genzyme)
• Collaboration (Ontogeny / Genzyme)
   

Chip/microarray technologies

Academic

• Microarray (Brown Lab Microarray Homepage)
• Ressourcenzentrum (Ressourcenzentrum im Deutschen Humangenomprojekt)

  Commercial

• Affymetrix (chip-technology)

Companies/orders

• Biosupplynet (biomedical suppliers)
• Clontech (biotechnology supplier)
• Genetics Computer Group (GCG-supplier)
• Invitrogen (biotechnology supplier)
• Molecular Probes (fluorescent probes)

© 2002

Letzte Änderung: 27.4.02

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