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Freie Universität Berlin Charité University Medicine Berlin Humboldt University Berlin Max-Delbrück-Center for Molecular Medicine, Berlin-Buch |
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Freie Universität Berlin Charité University Medicine Berlin Humboldt University Berlin Max-Delbrück-Center for Molecular Medicine, Berlin-Buch |
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GRK 1123: |
Cellular Mechanisms of Learning and Memory Consolidation |
This Research Training Group is funded by the German Research Council DFG
| Jochen Decker Address: Institute für Neurophysiologie Charité, Universitätsmedizin Berlin Tucholskystr. 2 D-10117 Berlin Tel +49 (30) 450-528138 Fax +49 (30) 450-528962 |
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| MD-Project "Investigation of the VILIP-1/GC-B signalling complex and its role in synaptic plasticity" Synopsis VILIP 1 is a neuronal calcium sensor protein that is prominently expressed in the hippocampus. It is known that it has a regulatory function on the surface expression and activity of neuronal receptors like the nicotinic ACh receptor and the membrane standing guanylyl cyclase B. In my project the functional implication of VILIP 1 on synaptic plasticity via the guanyly cyclase B will be investigated by whole-cell patch clamp technique of dissociated hippocampal neurons overexpressing VILIP 1.
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